sequence (NextProt isoform, UniProt entry, common name, gene name)COFACTOR (MF in red, BP in blue, CC in green)UniProt GO (reviewed in black; IEA-only in grey)
UniProt annotation score (1 to 5)
NextProt GO (GOLD in black; SILVER in grey)
Tissue-specific protein expression
(Human Protein Atlas)
Tissue-specific RNA expression
(GTEx Portal)
1>NX_Q8TBR7-2|FA57A_HUMAN FAM57A GN=FAM57A
MLLTLAGGALFFPGLFALCTWALRRSQPGWSRTDCVMISTRLVSSVHAVL
ATGSGIVIIRSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTR
DQNRAPSLTLRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCI
FTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTLATFLSCRILLFPFMY
WSYGRQQGLSLLQVPFSIPFYCNVANAFLVAPQIYWFCLLCRKAVRLFDT
PQAKKDG


chromosome location: 732412-742972 (17p13.3)

Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0016740_(1.00)_transferase_activity
    GO:0050291_(0.99)_sphingosine_N-acyltransferase
    activity
    GO:0042277_(0.21)_peptide_binding
    GO:0004985_(0.21)_opioid_receptor_activity
    GO:1901338_(0.20)_catecholamine_binding
    GO:0050780_(0.20)_dopamine_receptor_binding
    GO:0008227_(0.20)_G-protein_coupled_amine_receptor
    activity
    GO:0004952_(0.20)_dopamine_neurotransmitter
    receptor_activity
    GO:0042802_(0.18)_identical_protein_binding
    GO:0020037_(0.18)_heme_binding
    GO:0019899_(0.18)_enzyme_binding
    GO:0009055_(0.18)_electron_carrier_activity
    GO:0005506_(0.18)_iron_ion_binding
    GO:0003796_(0.18)_lysozyme_activity
    GO:0001609_(0.18)_G-protein_coupled_adenosine
    receptor_activity
    BP:
    GO:0044763_(0.99)_single-organism_cellular_process
    GO:0032502_(0.69)_developmental_process
    GO:0044767_(0.64)_single-organism_developmental
    process
    GO:0048856_(0.59)_anatomical_structure_development
    GO:1901564_(0.57)_organonitrogen_compound
    metabolic_process
    GO:0044237_(0.57)_cellular_metabolic_process
    GO:0006629_(0.57)_lipid_metabolic_process
    GO:0048869_(0.55)_cellular_developmental_process
    GO:0016043_(0.54)_cellular_component_organization
    GO:0007420_(0.54)_brain_development
    GO:0021952_(0.53)_central_nervous_system
    projection_neuron_axonogenesis
    GO:0001654_(0.53)_eye_development
    GO:0006672_(0.46)_ceramide_metabolic_process
    GO:0046467_(0.42)_membrane_lipid_biosynthetic
    process
    GO:0046513_(0.41)_ceramide_biosynthetic_process
    CC:
    GO:0005887_(1.00)_integral_component_of_plasma
    membrane
    GO:0005886_(1.00)_plasma_membrane
    GO:0044444_(0.99)_cytoplasmic_part
    GO:0043229_(0.99)_intracellular_organelle
    GO:0043227_(0.99)_membrane-bounded_organelle
    GO:0005783_(0.98)_endoplasmic_reticulum
    GO:0097458_(0.37)_neuron_part
    GO:0042995_(0.37)_cell_projection
    GO:0098590_(0.29)_plasma_membrane_region
    GO:0044463_(0.29)_cell_projection_part
    GO:0005794_(0.29)_Golgi_apparatus
    GO:0005737_(0.29)_cytoplasm
    GO:0043005_(0.25)_neuron_projection
    GO:0030430_(0.25)_host_cell_cytoplasm
    GO:0044456_(0.22)_synapse_part
    UniProt annotation:
    GO:0005886_plasma_membrane
    GO:0005515_protein_binding
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005515_protein_binding
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_100.10
  • Skin_-_Sun_Exposed_(Lower_leg):_82.99
  • Cells_-_Transformed_fibroblasts:_40.88
  • Esophagus_-_Mucosa:_31.07
  • Vagina:_30.35
  • Cells_-_EBV-transformed_lymphocytes:_25.44
  • Testis:_19.01
  • Cervix_-_Ectocervix:_18.05
  • Pituitary:_16.76
  • Prostate:_16.61
  • Bladder:_16.54
  • Cervix_-_Endocervix:_16.34
  • Stomach:_15.38
  • Minor_Salivary_Gland:_15.32
  • Nerve_-_Tibial:_14.37
  • Brain_-_Cerebellum:_13.71
  • Brain_-_Cerebellar_Hemisphere:_13.55
  • Fallopian_Tube:_13.53
  • Uterus:_12.82
  • Thyroid:_12.66
  • Lung:_11.68
  • Ovary:_11.06
  • Artery_-_Aorta:_10.85
  • Adipose_-_Visceral_(Omentum):_10.33
  • Artery_-_Coronary:_10.08
  • Breast_-_Mammary_Tissue:_8.65
  • Small_Intestine_-_Terminal_Ileum:_8.53
  • Adipose_-_Subcutaneous:_8.52
  • Esophagus_-_Gastroesophageal_Junction:_7.72
  • Esophagus_-_Muscularis:_7.70
  • Colon_-_Transverse:_7.62
  • Artery_-_Tibial:_7.52
  • Colon_-_Sigmoid:_7.13
  • Brain_-_Hypothalamus:_6.04
  • Brain_-_Frontal_Cortex_(BA9):_5.93
  • Brain_-_Cortex:_5.89
  • Brain_-_Anterior_cingulate_cortex_(BA24):_5.04
  • Spleen:_5.00
  • Brain_-_Amygdala:_4.96
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_4.93
  • Kidney_-_Cortex:_4.79
  • Pancreas:_4.79
  • Brain_-_Caudate_(basal_ganglia):_4.42
  • Brain_-_Hippocampus:_4.20
  • Brain_-_Substantia_nigra:_4.05
  • Heart_-_Atrial_Appendage:_3.92
  • Adrenal_Gland:_3.82
  • Brain_-_Putamen_(basal_ganglia):_3.78
  • Brain_-_Spinal_cord_(cervical_c-1):_3.61
  • Heart_-_Left_Ventricle:_1.89
  • Liver:_1.20
  • Muscle_-_Skeletal:_1.12
  • Whole_Blood:_0.50
  • 2>NX_A6NGC4-1|TLCD2_HUMAN TLC domain-containing protein 2 GN=TLCD2
    MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSL
    LSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQ
    TLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKL
    LLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALV
    TLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDN
    GPVTSNSSTLSLKD


    chromosome location: 1702790-1710438 (17p13.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0016740_(0.86)_transferase_activity
    GO:0050291_(0.76)_sphingosine_N-acyltransferase
    activity
    GO:0005216_(0.59)_ion_channel_activity
    GO:0009881_(0.55)_photoreceptor_activity
    GO:0051377_(0.05)_mannose-ethanolamine
    phosphotransferase_activity
    GO:0008757_(0.05)_S-adenosylmethionine-dependent
    methyltransferase_activity
    BP:
    GO:0044763_(0.97)_single-organism_cellular_process
    GO:0008152_(0.90)_metabolic_process
    GO:0071704_(0.89)_organic_substance_metabolic
    process
    GO:0044238_(0.89)_primary_metabolic_process
    GO:0044237_(0.89)_cellular_metabolic_process
    GO:0006643_(0.76)_membrane_lipid_metabolic_process
    GO:0006672_(0.73)_ceramide_metabolic_process
    GO:0044765_(0.61)_single-organism_transport
    GO:0050794_(0.60)_regulation_of_cellular_process
    GO:0006811_(0.60)_ion_transport
    GO:0034220_(0.58)_ion_transmembrane_transport
    GO:0019538_(0.58)_protein_metabolic_process
    GO:0044267_(0.56)_cellular_protein_metabolic
    process
    GO:0050896_(0.55)_response_to_stimulus
    GO:0006464_(0.54)_cellular_protein_modification
    process
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0016021_(1.00)_integral_component_of_membrane
    GO:0016020_(1.00)_membrane
    GO:0044424_(0.81)_intracellular_part
    GO:0044444_(0.77)_cytoplasmic_part
    GO:0005783_(0.75)_endoplasmic_reticulum
    GO:0005886_(0.55)_plasma_membrane
    GO:0005793_(0.24)_endoplasmic_reticulum-Golgi
    intermediate_compartment
    GO:0005794_(0.04)_Golgi_apparatus
    GO:0005789_(0.03)_endoplasmic_reticulum_membrane
    GO:0005737_(0.03)_cytoplasm
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

  • Adrenal_Gland:_8.64
  • Adipose_-_Subcutaneous:_7.79
  • Cells_-_Transformed_fibroblasts:_7.48
  • Colon_-_Transverse:_7.12
  • Small_Intestine_-_Terminal_Ileum:_6.85
  • Nerve_-_Tibial:_5.68
  • Adipose_-_Visceral_(Omentum):_5.52
  • Lung:_5.01
  • Bladder:_4.88
  • Cervix_-_Ectocervix:_4.74
  • Esophagus_-_Mucosa:_4.72
  • Fallopian_Tube:_4.37
  • Vagina:_4.35
  • Breast_-_Mammary_Tissue:_4.20
  • Cervix_-_Endocervix:_3.85
  • Ovary:_3.33
  • Artery_-_Tibial:_3.31
  • Minor_Salivary_Gland:_3.27
  • Artery_-_Coronary:_2.82
  • Esophagus_-_Muscularis:_2.69
  • Uterus:_2.66
  • Artery_-_Aorta:_2.66
  • Esophagus_-_Gastroesophageal_Junction:_2.50
  • Colon_-_Sigmoid:_2.48
  • Liver:_2.46
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_2.17
  • Stomach:_2.07
  • Skin_-_Sun_Exposed_(Lower_leg):_2.03
  • Thyroid:_2.01
  • Prostate:_1.76
  • Spleen:_1.09
  • Heart_-_Atrial_Appendage:_1.05
  • Pituitary:_0.99
  • Kidney_-_Cortex:_0.82
  • Testis:_0.77
  • Heart_-_Left_Ventricle:_0.57
  • Muscle_-_Skeletal:_0.56
  • Pancreas:_0.52
  • Brain_-_Spinal_cord_(cervical_c-1):_0.39
  • Brain_-_Cortex:_0.26
  • Brain_-_Hypothalamus:_0.25
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.25
  • Brain_-_Frontal_Cortex_(BA9):_0.24
  • Brain_-_Caudate_(basal_ganglia):_0.23
  • Brain_-_Hippocampus:_0.23
  • Brain_-_Substantia_nigra:_0.22
  • Brain_-_Putamen_(basal_ganglia):_0.22
  • Brain_-_Amygdala:_0.22
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.20
  • Brain_-_Cerebellum:_0.20
  • Brain_-_Cerebellar_Hemisphere:_0.14
  • Whole_Blood:_0.09
  • Cells_-_EBV-transformed_lymphocytes:_0.07
  • 3>NX_O43149-1|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 GN=ZZEF1
    MGNAPSHSSEDEAAAAGGEGWGPHQDWAAVSGTTPGPGVAAPALPPAAAL
    LEPARLREAAAALLPTPPCESLVSRHRGALFRWLEERLGRGEESVTLEQF
    RELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQG
    ELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVM
    PYPMLEHCNNMCTMRSSVLKESLDQLVQKEKESPGDLTRSPEMDKLKSVA
    KCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRH
    LSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENA
    NVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYW
    SLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSP
    NVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHL
    DTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLL
    VEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGL
    VFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDD
    PIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTIS
    GYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQ
    KESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSC
    FSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPME
    ILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMNVTEQEHKQSLQLTFRSL
    CTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLS
    GAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQ
    FLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIP
    HCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQEQPVVLHTWTKESA
    HNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRY
    DTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAV
    SWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLW
    KPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPA
    QNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPD
    LYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEA
    EEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADET
    SHLQPLNKRQRTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPKLPSS
    SGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTV
    KEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAE
    SLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQ
    LVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDI
    QLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEA
    WYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQC
    SDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCD
    DFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSW
    LLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKA
    HQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKKAVQGAEL
    SEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASP
    PTGLPDAEDSEVSSQKPIEEKAVTPSPEQVFAECSQKRILGLLAAMLPPL
    KSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPA
    EVDAAVIKVLSAKHNLFAAGDSSIVPDGWKTTHLLFSLGAVCLDSRVGLD
    WACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVG
    FPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKD
    YQLVQKGGGQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATW
    VLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLL
    RDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSSPGDPEQ
    KKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQ
    KRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRP
    ARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSK
    RAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMT
    YILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQ
    VRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSD
    FQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLG
    RFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLL
    LRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALT
    ELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYP
    NKATRLWNVEC


    chromosome location: 4004445-4143020 (17p13.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.56)_catalytic_activity
    GO:0016740_(0.53)_transferase_activity
    GO:0004842_(0.32)_ubiquitin-protein_transferase
    activity
    GO:0004672_(0.13)_protein_kinase_activity
    GO:0044877_(0.12)_macromolecular_complex_binding
    GO:0043169_(0.12)_cation_binding
    GO:0009931_(0.12)_calcium-dependent_protein
    serine/threonine_kinase_activity
    GO:0005516_(0.12)_calmodulin_binding
    GO:0004683_(0.12)_calmodulin-dependent_protein
    kinase_activity
    GO:0046872_(0.11)_metal_ion_binding
    GO:0043130_(0.11)_ubiquitin_binding
    GO:0005509_(0.10)_calcium_ion_binding
    GO:0042802_(0.09)_identical_protein_binding
    GO:0008092_(0.09)_cytoskeletal_protein_binding
    GO:0003700_(0.09)_transcription_factor_activity,
    sequence-specific_DNA_binding
    BP:
    GO:0009987_(0.84)_cellular_process
    GO:0043170_(0.64)_macromolecule_metabolic_process
    GO:0044238_(0.63)_primary_metabolic_process
    GO:0044260_(0.61)_cellular_macromolecule_metabolic
    process
    GO:0019538_(0.61)_protein_metabolic_process
    GO:0065007_(0.50)_biological_regulation
    GO:0006464_(0.50)_cellular_protein_modification
    process
    GO:0050789_(0.49)_regulation_of_biological_process
    GO:0050794_(0.44)_regulation_of_cellular_process
    GO:0032446_(0.36)_protein_modification_by_small
    protein_conjugation
    GO:0016567_(0.35)_protein_ubiquitination
    GO:0044699_(0.31)_single-organism_process
    GO:0048518_(0.24)_positive_regulation_of
    biological_process
    GO:0042787_(0.23)_protein_ubiquitination_involved
    in_ubiquitin-dependent_protein_catabolic_process
    GO:0048522_(0.21)_positive_regulation_of_cellular
    process
    CC:
    GO:0044464_(0.91)_cell_part
    GO:0044424_(0.83)_intracellular_part
    GO:0043226_(0.65)_organelle
    GO:0043229_(0.62)_intracellular_organelle
    GO:0043227_(0.62)_membrane-bounded_organelle
    GO:0043231_(0.58)_intracellular_membrane-bounded
    organelle
    GO:0005634_(0.47)_nucleus
    GO:0005737_(0.46)_cytoplasm
    GO:0032991_(0.28)_macromolecular_complex
    GO:0043234_(0.27)_protein_complex
    GO:0044422_(0.24)_organelle_part
    GO:0044446_(0.23)_intracellular_organelle_part
    GO:0044444_(0.21)_cytoplasmic_part
    GO:0016020_(0.19)_membrane
    GO:0044428_(0.17)_nuclear_part
    UniProt annotation:
    GO:0008270_zinc_ion_binding
    GO:0005509_calcium_ion_binding
    GO:0046872_metal_ion_binding

    UniProt annotation score: ◉◉◉◉◉

    NextProt annotation:
    GO:0005509_calcium_ion_binding
    GO:0008270_zinc_ion_binding
  • Small_Intestine_-_Terminal_Ileum:_43.22
  • Esophagus_-_Muscularis:_31.11
  • Colon_-_Transverse:_28.12
  • Esophagus_-_Gastroesophageal_Junction:_27.03
  • Spleen:_27.02
  • Thyroid:_25.73
  • Uterus:_25.32
  • Bladder:_25.27
  • Brain_-_Cerebellum:_25.15
  • Artery_-_Tibial:_24.35
  • Ovary:_23.78
  • Lung:_23.66
  • Brain_-_Cerebellar_Hemisphere:_23.14
  • Pituitary:_23.03
  • Colon_-_Sigmoid:_22.73
  • Artery_-_Aorta:_22.63
  • Fallopian_Tube:_22.41
  • Nerve_-_Tibial:_22.25
  • Prostate:_21.86
  • Skin_-_Sun_Exposed_(Lower_leg):_21.84
  • Cervix_-_Endocervix:_21.42
  • Testis:_20.41
  • Cells_-_EBV-transformed_lymphocytes:_20.20
  • Artery_-_Coronary:_20.08
  • Cervix_-_Ectocervix:_20.04
  • Adipose_-_Subcutaneous:_19.91
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_19.85
  • Breast_-_Mammary_Tissue:_19.05
  • Muscle_-_Skeletal:_17.50
  • Esophagus_-_Mucosa:_17.39
  • Vagina:_17.06
  • Stomach:_16.68
  • Adrenal_Gland:_15.86
  • Minor_Salivary_Gland:_15.42
  • Cells_-_Transformed_fibroblasts:_15.19
  • Adipose_-_Visceral_(Omentum):_14.74
  • Pancreas:_10.72
  • Whole_Blood:_10.16
  • Brain_-_Cortex:_9.82
  • Heart_-_Atrial_Appendage:_9.15
  • Brain_-_Spinal_cord_(cervical_c-1):_8.98
  • Brain_-_Frontal_Cortex_(BA9):_8.79
  • Kidney_-_Cortex:_8.35
  • Brain_-_Hypothalamus:_7.76
  • Heart_-_Left_Ventricle:_7.27
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_6.99
  • Brain_-_Substantia_nigra:_6.88
  • Brain_-_Caudate_(basal_ganglia):_6.35
  • Liver:_6.34
  • Brain_-_Hippocampus:_6.33
  • Brain_-_Anterior_cingulate_cortex_(BA24):_6.28
  • Brain_-_Putamen_(basal_ganglia):_5.75
  • Brain_-_Amygdala:_5.46
  • 4>NX_Q2TAL5-1|SMTL2_HUMAN Smoothelin-like protein 2 GN=SMTNL2
    MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAM
    RLAGPLARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTP
    SPPPAPGVPDRAPRLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSN
    SCIMENGHQPGAGPGDGPPEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAI
    TRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTPSPSEKNSSFT
    WSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRREL
    VRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASA
    SSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDY
    NSLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYV
    QSLYNHLRRFE


    chromosome location: 4583999-4608319 (17p13.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0008092_(0.77)_cytoskeletal_protein_binding
    GO:0003779_(0.42)_actin_binding
    GO:1901363_(0.40)_heterocyclic_compound_binding
    GO:0097159_(0.40)_organic_cyclic_compound_binding
    GO:0050660_(0.37)_flavin_adenine_dinucleotide
    binding
    GO:0046983_(0.30)_protein_dimerization_activity
    GO:0042802_(0.30)_identical_protein_binding
    GO:0042803_(0.29)_protein_homodimerization
    activity
    GO:0003824_(0.29)_catalytic_activity
    GO:0019899_(0.28)_enzyme_binding
    GO:0017166_(0.28)_vinculin_binding
    GO:0051393_(0.25)_alpha-actinin_binding
    GO:0019904_(0.22)_protein_domain_specific_binding
    GO:0017016_(0.22)_Ras_GTPase_binding
    GO:0016705_(0.22)_oxidoreductase_activity,_acting
    on_paired_donors,_with_incorporation_or_reduction
    of_molecular_oxygen
    BP:
    GO:0044699_(0.86)_single-organism_process
    GO:0009987_(0.82)_cellular_process
    GO:0044763_(0.76)_single-organism_cellular_process
    GO:0016043_(0.70)_cellular_component_organization
    GO:0032502_(0.69)_developmental_process
    GO:0044767_(0.63)_single-organism_developmental
    process
    GO:0048856_(0.59)_anatomical_structure_development
    GO:0065007_(0.51)_biological_regulation
    GO:0050789_(0.47)_regulation_of_biological_process
    GO:0006996_(0.47)_organelle_organization
    GO:0007010_(0.45)_cytoskeleton_organization
    GO:0050794_(0.44)_regulation_of_cellular_process
    GO:1902589_(0.42)_single-organism_organelle
    organization
    GO:0048869_(0.41)_cellular_developmental_process
    GO:0030029_(0.41)_actin_filament-based_process
    CC:
    GO:0044464_(0.99)_cell_part
    GO:0044424_(0.97)_intracellular_part
    GO:0044422_(0.75)_organelle_part
    GO:0043226_(0.73)_organelle
    GO:0044446_(0.71)_intracellular_organelle_part
    GO:0043229_(0.70)_intracellular_organelle
    GO:0044444_(0.68)_cytoplasmic_part
    GO:0005737_(0.66)_cytoplasm
    GO:0016020_(0.52)_membrane
    GO:0043232_(0.51)_intracellular_non-membrane-
    bounded_organelle
    GO:0044430_(0.50)_cytoskeletal_part
    GO:0044425_(0.44)_membrane_part
    GO:0005856_(0.43)_cytoskeleton
    GO:0043227_(0.42)_membrane-bounded_organelle
    GO:0005886_(0.42)_plasma_membrane

    UniProt annotation score: ◉◉○○○

  • Muscle_-_Skeletal:_280.65
  • Kidney_-_Cortex:_25.27
  • Fallopian_Tube:_14.21
  • Ovary:_9.72
  • Adipose_-_Visceral_(Omentum):_9.01
  • Esophagus_-_Muscularis:_8.62
  • Heart_-_Left_Ventricle:_7.63
  • Lung:_6.71
  • Cervix_-_Ectocervix:_6.30
  • Cervix_-_Endocervix:_5.88
  • Nerve_-_Tibial:_5.83
  • Heart_-_Atrial_Appendage:_5.61
  • Uterus:_5.14
  • Esophagus_-_Gastroesophageal_Junction:_5.07
  • Bladder:_4.64
  • Vagina:_3.63
  • Prostate:_3.11
  • Breast_-_Mammary_Tissue:_2.85
  • Pituitary:_2.68
  • Adipose_-_Subcutaneous:_2.48
  • Esophagus_-_Mucosa:_2.43
  • Testis:_2.14
  • Artery_-_Coronary:_1.79
  • Thyroid:_1.63
  • Colon_-_Sigmoid:_1.38
  • Spleen:_1.22
  • Small_Intestine_-_Terminal_Ileum:_1.22
  • Minor_Salivary_Gland:_1.18
  • Skin_-_Sun_Exposed_(Lower_leg):_1.01
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.88
  • Stomach:_0.86
  • Colon_-_Transverse:_0.78
  • Artery_-_Tibial:_0.78
  • Artery_-_Aorta:_0.62
  • Brain_-_Hippocampus:_0.61
  • Brain_-_Cerebellum:_0.54
  • Brain_-_Cortex:_0.52
  • Brain_-_Caudate_(basal_ganglia):_0.42
  • Brain_-_Frontal_Cortex_(BA9):_0.40
  • Brain_-_Cerebellar_Hemisphere:_0.39
  • Brain_-_Spinal_cord_(cervical_c-1):_0.37
  • Brain_-_Putamen_(basal_ganglia):_0.36
  • Brain_-_Substantia_nigra:_0.33
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.32
  • Brain_-_Amygdala:_0.32
  • Brain_-_Hypothalamus:_0.32
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.27
  • Pancreas:_0.27
  • Adrenal_Gland:_0.14
  • Cells_-_EBV-transformed_lymphocytes:_0.08
  • Liver:_0.08
  • Whole_Blood:_0.08
  • Cells_-_Transformed_fibroblasts:_0.06
  • 5>NX_O14894-1|T4S5_HUMAN Transmembrane 4 L6 family member 5 GN=TM4SF5
    MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLM
    GGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLG
    AIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPR
    VVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH


    chromosome location: 4771884-4783213 (17p13.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0015370_(0.50)_solute:sodium_symporter_activity
    GO:0005326_(0.50)_neurotransmitter_transporter
    activity
    BP:
    GO:0048856_(1.00)_anatomical_structure_development
    GO:0044767_(1.00)_single-organism_developmental
    process
    GO:0044763_(0.76)_single-organism_cellular_process
    GO:2000227_(0.64)_negative_regulation_of
    pancreatic_A_cell_differentiation
    GO:2000077_(0.64)_negative_regulation_of_type_B
    pancreatic_cell_development
    GO:0090104_(0.64)_pancreatic_epsilon_cell
    differentiation
    GO:0031018_(0.64)_endocrine_pancreas_development
    GO:0042246_(0.36)_tissue_regeneration
    GO:0044765_(0.34)_single-organism_transport
    CC:
    GO:0016021_(1.00)_integral_component_of_membrane
    GO:0005887_(0.05)_integral_component_of_plasma
    membrane
    UniProt annotation:
    GO:0005887_integral_component_of_plasma_membrane
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

  • Liver:_126.20
  • Small_Intestine_-_Terminal_Ileum:_53.03
  • Colon_-_Transverse:_10.47
  • Stomach:_8.42
  • Kidney_-_Cortex:_8.34
  • Pancreas:_0.33
  • Testis:_0.20
  • Adrenal_Gland:_0.12
  • Colon_-_Sigmoid:_0.11
  • Cervix_-_Endocervix:_0.09
  • 6>NX_Q7Z5L0-1|VMO1_HUMAN Vitelline membrane outer layer protein 1 homolog GN=VMO1
    MERGAGAKLLPLLLLLRATGFTCAQTDGRNGYTAVIEVTSGGPWGDWAWP
    EMCPDGFFASGFSLKVEPPQGIPGDDTALNGIRLHCARGNVLGNTHVVES
    QSGSWGEWSEPLWCRGGAYLVAFSLRVEAPTTLGDNTAANNVRFRCSDGE
    ELQGPGLSWGDFGDWSDHCPKGACGLQTKIQGPRGLGDDTALNDARLFCC
    RS


    chromosome location: 4785285-4786433 (17p13.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0016787_(0.53)_hydrolase_activity
    GO:0008061_(0.36)_chitin_binding
    GO:0004568_(0.36)_chitinase_activity
    GO:0004551_(0.17)_nucleotide_diphosphatase
    activity
    GO:0004035_(0.17)_alkaline_phosphatase_activity
    GO:0030246_(0.15)_carbohydrate_binding
    GO:0004930_(0.14)_G-protein_coupled_receptor
    activity
    BP:
    GO:0065007_(0.36)_biological_regulation
    GO:0048856_(0.35)_anatomical_structure_development
    GO:0050794_(0.32)_regulation_of_cellular_process
    GO:0071711_(0.25)_basement_membrane_organization
    GO:0033334_(0.25)_fin_morphogenesis
    GO:0033333_(0.25)_fin_development
    GO:0006032_(0.25)_chitin_catabolic_process
    GO:0043569_(0.12)_negative_regulation_of_insulin-
    like_growth_factor_receptor_signaling_pathway
    GO:0051965_(0.10)_positive_regulation_of_synapse
    assembly
    GO:0007422_(0.10)_peripheral_nervous_system
    development
    GO:0007186_(0.10)_G-protein_coupled_receptor
    signaling_pathway
    GO:0001895_(0.07)_retina_homeostasis
    CC:
    GO:0070062_(1.00)_extracellular_exosome
    UniProt annotation:
    GO:0070062_extracellular_exosome
    GO:0005576_extracellular_region

    UniProt annotation score: ◉◉◉○○

  • Pituitary:_36.65
  • Spleen:_27.55
  • Lung:_12.54
  • Artery_-_Aorta:_11.17
  • Artery_-_Coronary:_7.36
  • Nerve_-_Tibial:_6.98
  • Cervix_-_Endocervix:_6.64
  • Liver:_5.87
  • Minor_Salivary_Gland:_5.44
  • Brain_-_Spinal_cord_(cervical_c-1):_5.05
  • Adipose_-_Visceral_(Omentum):_4.66
  • Prostate:_4.35
  • Adipose_-_Subcutaneous:_3.86
  • Artery_-_Tibial:_3.81
  • Vagina:_3.72
  • Brain_-_Cerebellum:_3.67
  • Brain_-_Cerebellar_Hemisphere:_3.66
  • Brain_-_Hypothalamus:_3.39
  • Small_Intestine_-_Terminal_Ileum:_3.22
  • Cells_-_Transformed_fibroblasts:_3.14
  • Skin_-_Sun_Exposed_(Lower_leg):_3.11
  • Uterus:_3.09
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_3.00
  • Breast_-_Mammary_Tissue:_2.77
  • Brain_-_Frontal_Cortex_(BA9):_2.72
  • Brain_-_Cortex:_2.68
  • Kidney_-_Cortex:_2.65
  • Brain_-_Substantia_nigra:_2.64
  • Adrenal_Gland:_2.63
  • Colon_-_Sigmoid:_2.57
  • Fallopian_Tube:_2.49
  • Cervix_-_Ectocervix:_2.43
  • Brain_-_Hippocampus:_2.40
  • Thyroid:_2.35
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_2.33
  • Brain_-_Anterior_cingulate_cortex_(BA24):_2.28
  • Whole_Blood:_2.10
  • Esophagus_-_Mucosa:_2.06
  • Colon_-_Transverse:_1.99
  • Brain_-_Amygdala:_1.98
  • Brain_-_Caudate_(basal_ganglia):_1.89
  • Bladder:_1.85
  • Esophagus_-_Gastroesophageal_Junction:_1.77
  • Brain_-_Putamen_(basal_ganglia):_1.67
  • Esophagus_-_Muscularis:_1.63
  • Ovary:_1.59
  • Testis:_1.50
  • Stomach:_1.40
  • Heart_-_Atrial_Appendage:_1.31
  • Pancreas:_0.69
  • Muscle_-_Skeletal:_0.60
  • Heart_-_Left_Ventricle:_0.45
  • Cells_-_EBV-transformed_lymphocytes:_0.14
  • 7>NX_A8MU93-1|CQ100_HUMAN Uncharacterized protein C17orf100 GN=C17orf100
    MASARGAKQSSPRVGTTRYTETSTVRVETSSHRVETSSRRVETSQRRSEG
    PSLSPSGKRLPRILEASSRHVESSSQRTETTSRHVRASSLRVETSLHCAE
    SPTPRPSRPPARTKKRPDEMLLPKGHQGARALSQDRKASSCQPASQLPGG
    PIIFGFMETNHKSM


    chromosome location: 6651718-6693202 (17p13.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.46)_catalytic_activity
    GO:0016787_(0.27)_hydrolase_activity
    GO:0016740_(0.25)_transferase_activity
    GO:0052689_(0.23)_carboxylic_ester_hydrolase
    activity
    GO:0033040_(0.22)_sour_taste_receptor_activity
    GO:0005262_(0.22)_calcium_channel_activity
    GO:1901363_(0.20)_heterocyclic_compound_binding
    GO:0097159_(0.20)_organic_cyclic_compound_binding
    GO:0003881_(0.20)_CDP-diacylglycerol-inositol
    3-phosphatidyltransferase_activity
    GO:0044822_(0.15)_poly(A)_RNA_binding
    GO:0008134_(0.15)_transcription_factor_binding
    GO:0003712_(0.15)_transcription_cofactor_activity
    GO:0001078_(0.15)_transcriptional_repressor
    activity,_RNA_polymerase_II_core_promoter_proximal
    region_sequence-specific_binding
    GO:0001047_(0.15)_core_promoter_binding
    GO:0000978_(0.15)_RNA_polymerase_II_core_promoter
    proximal_region_sequence-specific_DNA_binding
    BP:
    GO:0050794_(0.87)_regulation_of_cellular_process
    GO:0030308_(0.84)_negative_regulation_of_cell
    growth
    GO:0009987_(0.20)_cellular_process
    GO:0044699_(0.17)_single-organism_process
    GO:0044763_(0.14)_single-organism_cellular_process
    GO:0071704_(0.09)_organic_substance_metabolic
    process
    GO:0044710_(0.09)_single-organism_metabolic
    process
    GO:0044238_(0.09)_primary_metabolic_process
    GO:0044237_(0.09)_cellular_metabolic_process
    GO:0006810_(0.09)_transport
    GO:0048856_(0.08)_anatomical_structure_development
    GO:0006928_(0.08)_movement_of_cell_or_subcellular
    component
    GO:0051716_(0.06)_cellular_response_to_stimulus
    GO:0051017_(0.05)_actin_filament_bundle_assembly
    GO:0030048_(0.05)_actin_filament-based_movement
    CC:
    GO:0044464_(0.99)_cell_part
    GO:0044424_(0.98)_intracellular_part
    GO:0043226_(0.96)_organelle
    GO:0043227_(0.95)_membrane-bounded_organelle
    GO:0043229_(0.93)_intracellular_organelle
    GO:0043231_(0.92)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.88)_cytoplasm
    GO:0005634_(0.81)_nucleus
    GO:0043234_(0.77)_protein_complex
    GO:0016459_(0.76)_myosin_complex
    GO:0044444_(0.68)_cytoplasmic_part
    GO:0031988_(0.60)_membrane-bounded_vesicle
    GO:0016020_(0.59)_membrane
    GO:0042995_(0.44)_cell_projection
    GO:0016023_(0.44)_cytoplasmic,_membrane-bounded
    vesicle

    UniProt annotation score: ◉○○○○

  • Pituitary:_3.85
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_2.29
  • Skin_-_Sun_Exposed_(Lower_leg):_2.19
  • Testis:_2.12
  • Thyroid:_1.96
  • Esophagus_-_Mucosa:_1.91
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_1.24
  • Spleen:_1.17
  • Cells_-_EBV-transformed_lymphocytes:_1.11
  • Brain_-_Cerebellum:_0.78
  • Brain_-_Hypothalamus:_0.77
  • Brain_-_Cerebellar_Hemisphere:_0.77
  • Brain_-_Frontal_Cortex_(BA9):_0.74
  • Brain_-_Cortex:_0.73
  • Brain_-_Caudate_(basal_ganglia):_0.72
  • Vagina:_0.65
  • Prostate:_0.64
  • Fallopian_Tube:_0.60
  • Minor_Salivary_Gland:_0.60
  • Small_Intestine_-_Terminal_Ileum:_0.58
  • Brain_-_Putamen_(basal_ganglia):_0.52
  • Cervix_-_Ectocervix:_0.52
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.50
  • Cervix_-_Endocervix:_0.47
  • Brain_-_Spinal_cord_(cervical_c-1):_0.44
  • Bladder:_0.43
  • Lung:_0.40
  • Brain_-_Hippocampus:_0.38
  • Pancreas:_0.33
  • Brain_-_Amygdala:_0.30
  • Brain_-_Substantia_nigra:_0.30
  • Breast_-_Mammary_Tissue:_0.24
  • Kidney_-_Cortex:_0.21
  • Uterus:_0.20
  • Liver:_0.19
  • Ovary:_0.19
  • Colon_-_Transverse:_0.17
  • Cells_-_Transformed_fibroblasts:_0.15
  • Stomach:_0.14
  • Colon_-_Sigmoid:_0.14
  • Adipose_-_Visceral_(Omentum):_0.13
  • Adrenal_Gland:_0.11
  • Esophagus_-_Muscularis:_0.10
  • 8>NX_Q8N2U0-1|TM256_HUMAN Transmembrane protein 256 GN=TMEM256
    MAGPAAAFRRLGALSGAAALGFASYGAHGAQFPDAYGKELFDKANKHHFL
    HSLALLGVPHCRKPLWAGLLLASGTTLFCTSFYYQALSGDPSIQTLAPAG
    GTLLLLGWLALAL


    chromosome location: 7402975-7404137 (17p13.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0022892_(0.57)_substrate-specific_transporter
    activity
    GO:0017128_(0.55)_phospholipid_scramblase_activity
    GO:0003824_(0.47)_catalytic_activity
    GO:0008865_(0.45)_fructokinase_activity
    GO:0004454_(0.45)_ketohexokinase_activity
    GO:0042803_(0.04)_protein_homodimerization
    activity
    GO:0030955_(0.04)_potassium_ion_binding
    GO:0015081_(0.04)_sodium_ion_transmembrane
    transporter_activity
    GO:0009678_(0.04)_hydrogen-translocating
    pyrophosphatase_activity
    GO:0005509_(0.04)_calcium_ion_binding
    GO:0004427_(0.04)_inorganic_diphosphatase_activity
    GO:0000287_(0.04)_magnesium_ion_binding
    BP:
    GO:0009987_(0.59)_cellular_process
    GO:0046835_(0.57)_carbohydrate_phosphorylation
    GO:0006810_(0.46)_transport
    GO:0044351_(0.43)_macropinocytosis
    GO:0035725_(0.05)_sodium_ion_transmembrane
    transport
    GO:0015992_(0.05)_proton_transport
    CC:
    GO:0043227_(0.61)_membrane-bounded_organelle
    GO:0044464_(0.52)_cell_part
    GO:0070062_(0.51)_extracellular_exosome
    GO:0044424_(0.44)_intracellular_part
    GO:0016020_(0.41)_membrane
    GO:0044444_(0.34)_cytoplasmic_part
    GO:0044446_(0.26)_intracellular_organelle_part
    GO:0031090_(0.25)_organelle_membrane
    GO:0005743_(0.24)_mitochondrial_inner_membrane
    GO:0016021_(0.23)_integral_component_of_membrane
    GO:0043231_(0.10)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.10)_cytoplasm
    GO:0005783_(0.08)_endoplasmic_reticulum
    GO:0005886_(0.04)_plasma_membrane
    GO:0044437_(0.03)_vacuolar_part
    UniProt annotation:
    GO:0070062_extracellular_exosome
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

  • Cells_-_EBV-transformed_lymphocytes:_125.35
  • Nerve_-_Tibial:_114.20
  • Cervix_-_Endocervix:_101.50
  • Cervix_-_Ectocervix:_98.81
  • Ovary:_92.08
  • Fallopian_Tube:_88.67
  • Prostate:_86.75
  • Breast_-_Mammary_Tissue:_85.71
  • Adipose_-_Visceral_(Omentum):_83.41
  • Cells_-_Transformed_fibroblasts:_83.03
  • Uterus:_82.64
  • Small_Intestine_-_Terminal_Ileum:_81.49
  • Brain_-_Spinal_cord_(cervical_c-1):_80.98
  • Adipose_-_Subcutaneous:_77.24
  • Bladder:_75.93
  • Vagina:_74.54
  • Artery_-_Coronary:_71.48
  • Stomach:_68.31
  • Adrenal_Gland:_68.28
  • Spleen:_67.69
  • Liver:_67.41
  • Thyroid:_64.81
  • Esophagus_-_Gastroesophageal_Junction:_63.55
  • Colon_-_Sigmoid:_63.34
  • Artery_-_Aorta:_63.07
  • Kidney_-_Cortex:_63.00
  • Colon_-_Transverse:_61.34
  • Lung:_61.31
  • Esophagus_-_Mucosa:_60.46
  • Artery_-_Tibial:_59.78
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_58.70
  • Esophagus_-_Muscularis:_57.78
  • Minor_Salivary_Gland:_53.10
  • Brain_-_Substantia_nigra:_52.04
  • Pituitary:_51.26
  • Heart_-_Atrial_Appendage:_50.73
  • Skin_-_Sun_Exposed_(Lower_leg):_50.32
  • Pancreas:_45.33
  • Brain_-_Frontal_Cortex_(BA9):_39.32
  • Brain_-_Amygdala:_38.91
  • Brain_-_Anterior_cingulate_cortex_(BA24):_38.31
  • Brain_-_Hippocampus:_37.89
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_36.63
  • Brain_-_Hypothalamus:_36.63
  • Brain_-_Cerebellar_Hemisphere:_35.70
  • Brain_-_Caudate_(basal_ganglia):_34.95
  • Brain_-_Cerebellum:_33.35
  • Brain_-_Cortex:_33.01
  • Brain_-_Putamen_(basal_ganglia):_32.99
  • Heart_-_Left_Ventricle:_30.76
  • Muscle_-_Skeletal:_26.04
  • Testis:_17.31
  • Whole_Blood:_13.33
  • 9>NX_Q0P670-1|SPEM2_HUMAN Uncharacterized protein SPEM2 GN=SPEM2
    MENQLWHNTVRCCNQYQESPHDAEDILLLLLGLIVLVNIGINVATMMWHG
    LQNALDKMIDWATQKNEIQASESPPSGPPDKAQDVHIHCILDPVQVKMSR
    PTQYSSFSCHHFSNHHSSSLLRCVRRRRRRHRRCRRRCCNHQQRPQNYRQ
    IPHSHSVFRNPHRSQKMSQLHRVPFFDQEDPDSYLEEEDNLPFPYPKYPR
    RGWGGFYQRAGLPSNVGLWGHQGGILASLPPPSLYLSPELRCMPKRVEAR
    SELRLQSYGRHGSQSRLWGNVEAEQWASSPPPPHRLPPNPSWVPVGHSPY
    PSVGWMLYDSWDQRRRGTEGFERPPASVSRNARPEAQGCREHHSPQSHQQ
    SLLGHAYGQSHRSPHPSTEPLGYSSQDPREVRRRAADWAEALPAWRPLTT
    SASLTVLDEASHQRTPAPSSVLVPHSSQPWPKVQAADPAPPPTMFVPLSR
    NPGGNANYQVYDSLELKRQVQKSRARSSSLPPASTSTLRPSLHRSQTEKL
    N


    chromosome location: 7425615-7427568 (17p13.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • MF:
    GO:0003824_(0.43)_catalytic_activity
    GO:0005215_(0.25)_transporter_activity
    GO:0022892_(0.24)_substrate-specific_transporter
    activity
    GO:0008324_(0.23)_cation_transmembrane_transporter
    activity
    GO:0005261_(0.21)_cation_channel_activity
    GO:0046873_(0.19)_metal_ion_transmembrane
    transporter_activity
    GO:0022836_(0.18)_gated_channel_activity
    GO:0022843_(0.17)_voltage-gated_cation_channel
    activity
    GO:0005245_(0.16)_voltage-gated_calcium_channel
    activity
    GO:0016740_(0.13)_transferase_activity
    GO:1901363_(0.11)_heterocyclic_compound_binding
    GO:0097159_(0.11)_organic_cyclic_compound_binding
    GO:0016772_(0.11)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0019899_(0.10)_enzyme_binding
    GO:0003676_(0.10)_nucleic_acid_binding
    BP:
    GO:0009987_(0.72)_cellular_process
    GO:0044699_(0.62)_single-organism_process
    GO:0065007_(0.57)_biological_regulation
    GO:0044763_(0.54)_single-organism_cellular_process
    GO:0050789_(0.48)_regulation_of_biological_process
    GO:0050794_(0.47)_regulation_of_cellular_process
    GO:0044767_(0.36)_single-organism_developmental
    process
    GO:0051179_(0.29)_localization
    GO:0065008_(0.28)_regulation_of_biological_quality
    GO:0006810_(0.28)_transport
    GO:0016043_(0.23)_cellular_component_organization
    GO:0008152_(0.22)_metabolic_process
    GO:0071704_(0.21)_organic_substance_metabolic
    process
    GO:0044238_(0.21)_primary_metabolic_process
    GO:0044237_(0.21)_cellular_metabolic_process
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.95)_intracellular_part
    GO:0032991_(0.58)_macromolecular_complex
    GO:0043234_(0.57)_protein_complex
    GO:0005737_(0.53)_cytoplasm
    GO:0043226_(0.52)_organelle
    GO:0043229_(0.49)_intracellular_organelle
    GO:0044444_(0.46)_cytoplasmic_part
    GO:0044422_(0.40)_organelle_part
    GO:0044446_(0.39)_intracellular_organelle_part
    GO:0043227_(0.35)_membrane-bounded_organelle
    GO:0044428_(0.31)_nuclear_part
    GO:0043232_(0.31)_intracellular_non-membrane-
    bounded_organelle
    GO:0043231_(0.31)_intracellular_membrane-bounded
    organelle
    GO:0016020_(0.31)_membrane
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

    10>NX_Q96T59-1|CDRTF_HUMAN CMT1A duplicated region transcript 15 protein GN=CDRT15
    MFSCCFPTSRGCCFRNGGSESLFRRCRRRLIPHPRRLSPVVIRRIQVPQD
    SLGQALAGQATPEIPLGLQLHTVLVQEIQELIEAQTLAPGPCAEVRALPA
    PAAEPEPAWEEAPPERALELEGAPAKDQTNEELPEITEVPESIKRRLGRR
    VPAATPAPRGNLLLQAWMRVHSWASRLFAPNVLPGTGP


    chromosome location: 14235673-14236862 (17p12)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.69)_catalytic_activity
    GO:0030234_(0.57)_enzyme_regulator_activity
    GO:0016887_(0.55)_ATPase_activity
    GO:0003777_(0.55)_microtubule_motor_activity
    GO:0043178_(0.49)_alcohol_binding
    GO:0032934_(0.49)_sterol_binding
    GO:0015248_(0.49)_sterol_transporter_activity
    GO:0008047_(0.49)_enzyme_activator_activity
    GO:0071814_(0.40)_protein-lipid_complex_binding
    GO:0070405_(0.40)_ammonium_ion_binding
    GO:0042277_(0.40)_peptide_binding
    GO:0070325_(0.30)_lipoprotein_particle_receptor
    binding
    GO:0034190_(0.30)_apolipoprotein_receptor_binding
    GO:0004857_(0.30)_enzyme_inhibitor_activity
    GO:0071889_(0.19)_14-3-3_protein_binding
    BP:
    GO:0009987_(0.87)_cellular_process
    GO:0044699_(0.83)_single-organism_process
    GO:0044763_(0.79)_single-organism_cellular_process
    GO:0006810_(0.68)_transport
    GO:0050794_(0.64)_regulation_of_cellular_process
    GO:0016043_(0.57)_cellular_component_organization
    GO:0071702_(0.55)_organic_substance_transport
    GO:0006928_(0.55)_movement_of_cell_or_subcellular
    component
    GO:0007165_(0.54)_signal_transduction
    GO:0065008_(0.53)_regulation_of_biological_quality
    GO:0044707_(0.53)_single-multicellular_organism
    process
    GO:0051239_(0.52)_regulation_of_multicellular
    organismal_process
    GO:0055092_(0.49)_sterol_homeostasis
    GO:0045940_(0.49)_positive_regulation_of_steroid
    metabolic_process
    GO:0042157_(0.49)_lipoprotein_metabolic_process
    CC:
    GO:0044464_(0.97)_cell_part
    GO:0044424_(0.91)_intracellular_part
    GO:0016020_(0.79)_membrane
    GO:0044446_(0.73)_intracellular_organelle_part
    GO:0032991_(0.71)_macromolecular_complex
    GO:0044425_(0.62)_membrane_part
    GO:0044444_(0.60)_cytoplasmic_part
    GO:0043234_(0.54)_protein_complex
    GO:0043226_(0.54)_organelle
    GO:0016021_(0.54)_integral_component_of_membrane
    GO:0043229_(0.49)_intracellular_organelle
    GO:0043227_(0.49)_membrane-bounded_organelle
    GO:0044430_(0.47)_cytoskeletal_part
    GO:0005886_(0.47)_plasma_membrane
    GO:0043231_(0.44)_intracellular_membrane-bounded
    organelle

    UniProt annotation score: ◉○○○○

  • Testis:_18.64
  • Spleen:_0.41
  • Small_Intestine_-_Terminal_Ileum:_0.30
  • Brain_-_Cerebellum:_0.24
  • Cells_-_EBV-transformed_lymphocytes:_0.24
  • Esophagus_-_Mucosa:_0.23
  • Prostate:_0.20
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.20
  • Skin_-_Sun_Exposed_(Lower_leg):_0.19
  • Brain_-_Cerebellar_Hemisphere:_0.19
  • Cervix_-_Ectocervix:_0.17
  • Cells_-_Transformed_fibroblasts:_0.17
  • Lung:_0.17
  • Fallopian_Tube:_0.16
  • Vagina:_0.16
  • Colon_-_Transverse:_0.16
  • Liver:_0.15
  • Thyroid:_0.14
  • Minor_Salivary_Gland:_0.14
  • Artery_-_Aorta:_0.14
  • Cervix_-_Endocervix:_0.13
  • Stomach:_0.11
  • Ovary:_0.11
  • Pituitary:_0.11
  • Adrenal_Gland:_0.10
  • Uterus:_0.09
  • Heart_-_Atrial_Appendage:_0.09
  • Heart_-_Left_Ventricle:_0.08
  • Esophagus_-_Gastroesophageal_Junction:_0.08
  • Artery_-_Coronary:_0.08
  • Esophagus_-_Muscularis:_0.08
  • Brain_-_Spinal_cord_(cervical_c-1):_0.07
  • Breast_-_Mammary_Tissue:_0.07
  • Nerve_-_Tibial:_0.07
  • Kidney_-_Cortex:_0.07
  • Colon_-_Sigmoid:_0.06
  • Bladder:_0.06
  • Whole_Blood:_0.06
  • Adipose_-_Subcutaneous:_0.06
  • Adipose_-_Visceral_(Omentum):_0.06
  • Artery_-_Tibial:_0.05
  • Pancreas:_0.05
  • Brain_-_Frontal_Cortex_(BA9):_0.04
  • Muscle_-_Skeletal:_0.04
  • Brain_-_Cortex:_0.04
  • Brain_-_Hippocampus:_0.03
  • Brain_-_Substantia_nigra:_0.03
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.03
  • Brain_-_Hypothalamus:_0.03
  • 11>NX_Q8NAA5-1|LR75A_HUMAN Leucine-rich repeat-containing protein 75A GN=LRRC75A
    MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGMPP
    YHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYAS
    FRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQW
    RRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRC
    GEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRAVLRDL
    TDILKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILE
    LGEGPGSGEEVREGTVGQEDPGGGPVAPAEDHHEGKETVAAAQT


    chromosome location: 16441577-16492153 (17p11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • MF:
    GO:0030234_(0.37)_enzyme_regulator_activity
    GO:0004857_(0.36)_enzyme_inhibitor_activity
    GO:0005102_(0.20)_receptor_binding
    GO:0008134_(0.19)_transcription_factor_binding
    GO:0042974_(0.17)_retinoic_acid_receptor_binding
    GO:0003824_(0.16)_catalytic_activity
    GO:0097159_(0.14)_organic_cyclic_compound_binding
    GO:1901363_(0.13)_heterocyclic_compound_binding
    GO:0097367_(0.11)_carbohydrate_derivative_binding
    GO:0019899_(0.10)_enzyme_binding
    GO:0016740_(0.10)_transferase_activity
    GO:0019904_(0.09)_protein_domain_specific_binding
    GO:0004872_(0.08)_receptor_activity
    GO:0003676_(0.08)_nucleic_acid_binding
    GO:0008092_(0.07)_cytoskeletal_protein_binding
    BP:
    GO:0065007_(0.73)_biological_regulation
    GO:0050789_(0.73)_regulation_of_biological_process
    GO:0009987_(0.67)_cellular_process
    GO:0044699_(0.61)_single-organism_process
    GO:0050794_(0.54)_regulation_of_cellular_process
    GO:0071704_(0.48)_organic_substance_metabolic
    process
    GO:0044767_(0.48)_single-organism_developmental
    process
    GO:0044238_(0.47)_primary_metabolic_process
    GO:0043170_(0.47)_macromolecule_metabolic_process
    GO:0065009_(0.45)_regulation_of_molecular_function
    GO:0050790_(0.44)_regulation_of_catalytic_activity
    GO:0044237_(0.44)_cellular_metabolic_process
    GO:0051239_(0.43)_regulation_of_multicellular
    organismal_process
    GO:0044260_(0.43)_cellular_macromolecule_metabolic
    process
    GO:0019222_(0.40)_regulation_of_metabolic_process
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.89)_intracellular_part
    GO:0043226_(0.76)_organelle
    GO:0043227_(0.72)_membrane-bounded_organelle
    GO:0005737_(0.69)_cytoplasm
    GO:0043229_(0.63)_intracellular_organelle
    GO:0044444_(0.60)_cytoplasmic_part
    GO:0044446_(0.59)_intracellular_organelle_part
    GO:0043234_(0.58)_protein_complex
    GO:0016020_(0.57)_membrane
    GO:0043231_(0.56)_intracellular_membrane-bounded
    organelle
    GO:0005886_(0.45)_plasma_membrane
    GO:0044421_(0.38)_extracellular_region_part
    GO:0005634_(0.37)_nucleus
    GO:0031988_(0.36)_membrane-bounded_vesicle

    UniProt annotation score: ◉◉○○○

    12>NX_Q5M775-1|CYTSB_HUMAN Cytospin-B GN=SPECC1
    MRSAAKPWNPAIRAGGHGPDRVRPLPAASSGMKSSKSSTSLAFESRLSRL
    KRASSEDTLNKPGSTAASGVVRLKKTATAGAISELTESRLRSGTGAFTTT
    KRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTP
    STKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTL
    NAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVL
    KEKLIYLEHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEY
    KKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPF
    KSSKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSD
    QQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQER
    VKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEE
    ENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLEGLKME
    NGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNE
    LRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEK
    ASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQK
    SDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVK
    RKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAGR
    WPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQNISVHKTPRSPLS
    GIPVRTAPAAAVSPMQRHSTYSSVRPASRGVTQRLDLPDLPLSDILKGRT
    ETLKPDPHLRKSPSLESLSRPPSLGFGDTRLLSASTRAWKPQSKLSVERK
    DPLAALAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCAL
    LHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLYTDRP
    DWQSVMQYVAQIYKYFET


    chromosome location: 20009344-20319026 (17p11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0008092_(0.53)_cytoskeletal_protein_binding
    GO:0046983_(0.45)_protein_dimerization_activity
    GO:0042802_(0.45)_identical_protein_binding
    GO:0019899_(0.45)_enzyme_binding
    GO:0003779_(0.43)_actin_binding
    GO:0042805_(0.42)_actinin_binding
    GO:0005198_(0.41)_structural_molecule_activity
    GO:1901363_(0.40)_heterocyclic_compound_binding
    GO:0097367_(0.40)_carbohydrate_derivative_binding
    GO:0097159_(0.40)_organic_cyclic_compound_binding
    GO:0032403_(0.40)_protein_complex_binding
    GO:0003824_(0.39)_catalytic_activity
    GO:0051015_(0.38)_actin_filament_binding
    GO:0044389_(0.38)_ubiquitin-like_protein_ligase
    binding
    GO:0003676_(0.38)_nucleic_acid_binding
    BP:
    GO:0009987_(0.84)_cellular_process
    GO:0044699_(0.82)_single-organism_process
    GO:0044763_(0.74)_single-organism_cellular_process
    GO:0016043_(0.67)_cellular_component_organization
    GO:0032502_(0.62)_developmental_process
    GO:0044767_(0.60)_single-organism_developmental
    process
    GO:0006996_(0.55)_organelle_organization
    GO:0065007_(0.51)_biological_regulation
    GO:0048856_(0.51)_anatomical_structure_development
    GO:1902589_(0.49)_single-organism_organelle
    organization
    GO:0050789_(0.48)_regulation_of_biological_process
    GO:0007010_(0.48)_cytoskeleton_organization
    GO:0050794_(0.47)_regulation_of_cellular_process
    GO:0048869_(0.46)_cellular_developmental_process
    GO:0051179_(0.45)_localization
    CC:
    GO:0044464_(0.98)_cell_part
    GO:0044424_(0.97)_intracellular_part
    GO:0044422_(0.78)_organelle_part
    GO:0044446_(0.76)_intracellular_organelle_part
    GO:0043226_(0.75)_organelle
    GO:0043229_(0.71)_intracellular_organelle
    GO:0044430_(0.66)_cytoskeletal_part
    GO:0044444_(0.64)_cytoplasmic_part
    GO:0016020_(0.59)_membrane
    GO:0043232_(0.54)_intracellular_non-membrane-
    bounded_organelle
    GO:0044425_(0.52)_membrane_part
    GO:0030054_(0.51)_cell_junction
    GO:0005856_(0.51)_cytoskeleton
    GO:0005886_(0.48)_plasma_membrane
    GO:0044459_(0.47)_plasma_membrane_part
    UniProt annotation:
    GO:0016020_membrane
    GO:0005634_nucleus

    UniProt annotation score: ◉◉◉◉◉

    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • epididymis_(glandular_cells)
  • gallbladder_(glandular_cells)
  • rectum_(glandular_cells)
  • cervix,_uterine_(glandular_cells)
    Medium:
  • colon_(endothelial_cells;_glandular_cells)
  • kidney_(cells_in_glomeruli;_cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • caudate_(neuronal_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(cells_in_endometrial_stroma;
    glandular_cells)
  • endometrium_2_(cells_in_endometrial_stroma;
    glandular_cells)
  • salivary_gland_(glandular_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • duodenum_(glandular_cells)
  • cerebral_cortex_(neuronal_cells;_neuropil)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • placenta_(trophoblastic_cells)
  • hippocampus_(neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • breast_(glandular_cells;_myoepithelial_cells)
  • prostate_(glandular_cells)
  • pancreas_(exocrine_glandular_cells)
  • cerebellum_(cells_in_granular_layer)
  • spleen_(cells_in_red_pulp)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(adipocytes;_peripheral_nerve)
  • small_intestine_(glandular_cells)
  • soft_tissue_1_(chondrocytes;_fibroblasts;
    peripheral_nerve)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages;_pneumocytes)
  • ovary_(ovarian_stroma_cells)
  • skin_1_(fibroblasts)
  • skin_2_(epidermal_cells)
    Low:
  • cerebellum_(cells_in_molecular_layer)
  • hippocampus_(glial_cells)
  • fallopian_tube_(glandular_cells)
  • skin_1_(keratinocytes)
  • soft_tissue_2_(fibroblasts)
  • tonsil_(squamous_epithelial_cells)
  • skeletal_muscle_(myocytes)
  • thyroid_gland_(glandular_cells)
  • colon_(peripheral_nerve/ganglion)
  • soft_tissue_1_(adipocytes)
  • esophagus_(squamous_epithelial_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • cerebral_cortex_(glial_cells)
  • pancreas_(islets_of_Langerhans)
  • Brain_-_Spinal_cord_(cervical_c-1):_19.62
  • Testis:_17.61
  • Artery_-_Aorta:_17.25
  • Artery_-_Coronary:_13.11
  • Ovary:_12.19
  • Brain_-_Frontal_Cortex_(BA9):_12.16
  • Artery_-_Tibial:_12.14
  • Brain_-_Cortex:_11.96
  • Brain_-_Substantia_nigra:_11.32
  • Brain_-_Hippocampus:_10.12
  • Spleen:_9.58
  • Uterus:_9.46
  • Brain_-_Cerebellum:_9.33
  • Brain_-_Hypothalamus:_9.04
  • Adipose_-_Subcutaneous:_8.87
  • Brain_-_Cerebellar_Hemisphere:_8.75
  • Nerve_-_Tibial:_8.36
  • Brain_-_Amygdala:_8.30
  • Brain_-_Anterior_cingulate_cortex_(BA24):_8.08
  • Brain_-_Putamen_(basal_ganglia):_7.33
  • Brain_-_Caudate_(basal_ganglia):_7.25
  • Cells_-_EBV-transformed_lymphocytes:_7.20
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_6.97
  • Fallopian_Tube:_6.90
  • Colon_-_Transverse:_6.28
  • Adipose_-_Visceral_(Omentum):_6.27
  • Breast_-_Mammary_Tissue:_6.24
  • Stomach:_5.76
  • Adrenal_Gland:_5.70
  • Pituitary:_5.08
  • Small_Intestine_-_Terminal_Ileum:_4.84
  • Lung:_4.49
  • Cervix_-_Endocervix:_4.44
  • Thyroid:_4.40
  • Prostate:_4.26
  • Minor_Salivary_Gland:_3.74
  • Esophagus_-_Mucosa:_3.60
  • Cervix_-_Ectocervix:_3.59
  • Esophagus_-_Gastroesophageal_Junction:_3.15
  • Vagina:_2.95
  • Bladder:_2.83
  • Colon_-_Sigmoid:_2.51
  • Skin_-_Sun_Exposed_(Lower_leg):_2.44
  • Esophagus_-_Muscularis:_2.42
  • Whole_Blood:_2.18
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_2.10
  • Cells_-_Transformed_fibroblasts:_1.92
  • Kidney_-_Cortex:_1.75
  • Pancreas:_1.33
  • Heart_-_Atrial_Appendage:_1.23
  • Heart_-_Left_Ventricle:_1.06
  • Muscle_-_Skeletal:_0.97
  • Liver:_0.23
  • 13>NX_Q8N6N6-1|NATD1_HUMAN NATD1 GN=NATD1
    MAHSAAAVPLGALEQGCPIRVEHDRRRRQFTVRLNGCHDRAVLLYEYVGK
    RIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVK
    ENPLPQYLERLQP


    chromosome location: 21238870-21253410 (17p11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • MF:
    GO:0004402_(0.33)_histone_acetyltransferase
    activity
    BP:
    GO:0006473_(0.68)_protein_acetylation
    GO:0018393_(0.44)_internal_peptidyl-lysine
    acetylation
    GO:0001702_(0.37)_gastrulation_with_mouth_forming
    second
    GO:0016573_(0.35)_histone_acetylation
    GO:0006474_(0.35)_N-terminal_protein_amino_acid
    acetylation
    GO:0050794_(0.33)_regulation_of_cellular_process
    GO:0048523_(0.27)_negative_regulation_of_cellular
    process
    GO:0048518_(0.20)_positive_regulation_of
    biological_process
    GO:0007162_(0.17)_negative_regulation_of_cell
    adhesion
    GO:0050435_(0.14)_beta-amyloid_metabolic_process
    GO:0043066_(0.14)_negative_regulation_of_apoptotic
    process
    GO:0018003_(0.14)_peptidyl-lysine_N6-acetylation
    GO:0010628_(0.14)_positive_regulation_of_gene
    expression
    GO:0006749_(0.10)_glutathione_metabolic_process
    GO:0051586_(0.06)_positive_regulation_of_dopamine
    uptake_involved_in_synaptic_transmission
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0043227_(0.78)_membrane-bounded_organelle
    GO:0043231_(0.70)_intracellular_membrane-bounded
    organelle
    GO:0043234_(0.64)_protein_complex
    GO:0031248_(0.55)_protein_acetyltransferase
    complex
    GO:0044444_(0.53)_cytoplasmic_part
    GO:0044446_(0.46)_intracellular_organelle_part
    GO:0005737_(0.36)_cytoplasm
    GO:0044428_(0.33)_nuclear_part
    GO:0044427_(0.33)_chromosomal_part
    GO:0044425_(0.30)_membrane_part
    GO:0005634_(0.30)_nucleus
    GO:0005777_(0.28)_peroxisome
    GO:0016021_(0.26)_integral_component_of_membrane
    GO:0044454_(0.22)_nuclear_chromosome_part
    UniProt annotation:
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉○○○

    NextProt annotation:
    GO:0005515_protein_binding
    14>NX_A8MSI8-1|LYRM9_HUMAN LYR motif-containing protein 9 GN=LYRM9
    MAPLPGAELVRRPLQLYRYLLRCCQQLPTKGIQQHYKHAVRQSFRVHSDE
    DNPERIQQIIKRAIEDADWIMNKYKKQN


    chromosome location: 27878314-27894752 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.63)_catalytic_activity
    GO:0008137_(0.52)_NADH_dehydrogenase_(ubiquinone)
    activity
    GO:0031071_(0.11)_cysteine_desulfurase_activity
    GO:0051536_(0.06)_iron-sulfur_cluster_binding
    BP:
    GO:0009987_(0.71)_cellular_process
    GO:0044699_(0.50)_single-organism_process
    GO:0044763_(0.42)_single-organism_cellular_process
    GO:0022607_(0.41)_cellular_component_assembly
    GO:0043623_(0.36)_cellular_protein_complex
    assembly
    GO:0008152_(0.33)_metabolic_process
    GO:0070271_(0.32)_protein_complex_biogenesis
    GO:0033108_(0.32)_mitochondrial_respiratory_chain
    complex_assembly
    GO:0050794_(0.31)_regulation_of_cellular_process
    GO:0050896_(0.29)_response_to_stimulus
    GO:0044237_(0.28)_cellular_metabolic_process
    GO:0034553_(0.28)_mitochondrial_respiratory_chain
    complex_II_assembly
    GO:0016192_(0.28)_vesicle-mediated_transport
    GO:0051716_(0.26)_cellular_response_to_stimulus
    GO:0044710_(0.26)_single-organism_metabolic
    process
    CC:
    GO:0044424_(0.88)_intracellular_part
    GO:0044444_(0.83)_cytoplasmic_part
    GO:0043227_(0.82)_membrane-bounded_organelle
    GO:0043231_(0.75)_intracellular_membrane-bounded
    organelle
    GO:0044446_(0.65)_intracellular_organelle_part
    GO:0005737_(0.56)_cytoplasm
    GO:0005739_(0.53)_mitochondrion
    GO:0044421_(0.42)_extracellular_region_part
    GO:0070062_(0.40)_extracellular_exosome
    GO:0016020_(0.40)_membrane
    GO:0005576_(0.40)_extracellular_region
    GO:0031090_(0.26)_organelle_membrane
    GO:0005829_(0.26)_cytosol
    GO:0098805_(0.25)_whole_membrane
    GO:0098588_(0.25)_bounding_membrane_of_organelle

    UniProt annotation score: ◉◉○○○

  • Brain_-_Nucleus_accumbens_(basal_ganglia):_49.65
  • Brain_-_Anterior_cingulate_cortex_(BA24):_47.32
  • Brain_-_Frontal_Cortex_(BA9):_43.70
  • Nerve_-_Tibial:_43.53
  • Brain_-_Cortex:_39.62
  • Brain_-_Amygdala:_35.88
  • Thyroid:_33.59
  • Adrenal_Gland:_32.92
  • Pituitary:_31.76
  • Brain_-_Hippocampus:_31.04
  • Brain_-_Hypothalamus:_30.89
  • Ovary:_29.91
  • Brain_-_Caudate_(basal_ganglia):_29.16
  • Testis:_24.35
  • Brain_-_Putamen_(basal_ganglia):_24.18
  • Cervix_-_Endocervix:_22.66
  • Brain_-_Cerebellar_Hemisphere:_22.33
  • Brain_-_Cerebellum:_21.83
  • Brain_-_Substantia_nigra:_21.66
  • Uterus:_21.61
  • Fallopian_Tube:_19.71
  • Brain_-_Spinal_cord_(cervical_c-1):_19.26
  • Prostate:_18.25
  • Adipose_-_Subcutaneous:_17.05
  • Breast_-_Mammary_Tissue:_16.66
  • Cervix_-_Ectocervix:_16.07
  • Spleen:_15.59
  • Artery_-_Tibial:_14.87
  • Kidney_-_Cortex:_14.54
  • Colon_-_Sigmoid:_14.42
  • Artery_-_Coronary:_13.84
  • Esophagus_-_Gastroesophageal_Junction:_13.79
  • Artery_-_Aorta:_13.42
  • Skin_-_Sun_Exposed_(Lower_leg):_13.34
  • Esophagus_-_Muscularis:_12.98
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_12.23
  • Bladder:_11.92
  • Vagina:_10.48
  • Minor_Salivary_Gland:_10.30
  • Lung:_10.10
  • Small_Intestine_-_Terminal_Ileum:_8.73
  • Adipose_-_Visceral_(Omentum):_8.69
  • Stomach:_8.44
  • Pancreas:_8.09
  • Cells_-_Transformed_fibroblasts:_8.01
  • Cells_-_EBV-transformed_lymphocytes:_7.20
  • Muscle_-_Skeletal:_7.04
  • Colon_-_Transverse:_6.99
  • Heart_-_Atrial_Appendage:_6.89
  • Liver:_5.42
  • Heart_-_Left_Ventricle:_4.19
  • Esophagus_-_Mucosa:_3.77
  • Whole_Blood:_3.06
  • 15>NX_P0DI83-1|NARR_HUMAN Ras-related protein Rab-34, isoform NARR GN=RAB34
    MVGQPQPRDDVGSPRPRVIVGTIRPRVIVGTIRPRVIVGSARARPPPDGT
    PRPQLAAEESPRPRVIFGTPRARVILGSPRPRVIVSSPWPAVVVASPRPR
    TPVGSPWPRVVVGTPRPRVIVGSPRARVADADPASAPSQGALQGRRQDEH
    SGTRAEGSRPGGAAPVPEEGGRFARAQRLPPPRHLRLPGAPDRHRGQI


    chromosome location: 28714281-28718429 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003824_(0.33)_catalytic_activity
    GO:0003700_(0.25)_transcription_factor_activity,
    sequence-specific_DNA_binding
    GO:0000981_(0.23)_RNA_polymerase_II_transcription
    factor_activity,_sequence-specific_DNA_binding
    GO:1901363_(0.19)_heterocyclic_compound_binding
    GO:0097159_(0.19)_organic_cyclic_compound_binding
    GO:0016740_(0.19)_transferase_activity
    GO:0016787_(0.18)_hydrolase_activity
    GO:0016772_(0.17)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0003676_(0.17)_nucleic_acid_binding
    GO:0003723_(0.14)_RNA_binding
    GO:0005198_(0.12)_structural_molecule_activity
    GO:0044877_(0.10)_macromolecular_complex_binding
    GO:0016779_(0.10)_nucleotidyltransferase_activity
    GO:0034062_(0.09)_RNA_polymerase_activity
    GO:0008092_(0.09)_cytoskeletal_protein_binding
    BP:
    GO:0009987_(0.59)_cellular_process
    GO:0065007_(0.56)_biological_regulation
    GO:0032502_(0.51)_developmental_process
    GO:0050794_(0.50)_regulation_of_cellular_process
    GO:0044699_(0.49)_single-organism_process
    GO:0044763_(0.41)_single-organism_cellular_process
    GO:0016043_(0.32)_cellular_component_organization
    GO:0080090_(0.31)_regulation_of_primary_metabolic
    process
    GO:0060255_(0.31)_regulation_of_macromolecule
    metabolic_process
    GO:0031323_(0.31)_regulation_of_cellular_metabolic
    process
    GO:0031326_(0.30)_regulation_of_cellular
    biosynthetic_process
    GO:2000112_(0.29)_regulation_of_cellular
    macromolecule_biosynthetic_process
    GO:0019219_(0.29)_regulation_of_nucleobase-
    containing_compound_metabolic_process
    GO:0006355_(0.28)_regulation_of_transcription,
    DNA-templated
    GO:0008152_(0.27)_metabolic_process
    CC:
    GO:0044464_(0.88)_cell_part
    GO:0044424_(0.73)_intracellular_part
    GO:0044422_(0.50)_organelle_part
    GO:0044446_(0.48)_intracellular_organelle_part
    GO:0032991_(0.46)_macromolecular_complex
    GO:0016020_(0.46)_membrane
    GO:0044425_(0.44)_membrane_part
    GO:0043234_(0.43)_protein_complex
    GO:0043226_(0.42)_organelle
    GO:0043229_(0.41)_intracellular_organelle
    GO:0043227_(0.38)_membrane-bounded_organelle
    GO:0044444_(0.36)_cytoplasmic_part
    GO:0031224_(0.36)_intrinsic_component_of_membrane
    GO:0043231_(0.35)_intracellular_membrane-bounded
    organelle
    GO:0016021_(0.31)_integral_component_of_membrane
    UniProt annotation:
    GO:0005730_nucleolus
    GO:0005634_nucleus

    UniProt annotation score: ◉◉◉◉◉

    High:
  • stomach_2_(glandular_cells)
  • testis_(Leydig_cells)
  • stomach_1_(glandular_cells)
  • parathyroid_gland_(glandular_cells)
  • small_intestine_(glandular_cells)
  • duodenum_(glandular_cells)
  • prostate_(glandular_cells)
  • pancreas_(islets_of_Langerhans)
    Medium:
  • colon_(glandular_cells;_peripheral
    nerve/ganglion)
  • gallbladder_(glandular_cells)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts)
  • thyroid_gland_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • cerebral_cortex_(neuronal_cells;_neuropil)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • bronchus_(respiratory_epithelial_cells)
  • skeletal_muscle_(myocytes)
  • urinary_bladder_(urothelial_cells)
  • liver_(hepatocytes)
  • rectum_(glandular_cells)
  • cervix,_uterine_(glandular_cells)
  • cerebellum_(cells_in_granular_layer)
  • soft_tissue_1_(adipocytes;_peripheral_nerve)
  • soft_tissue_2_(adipocytes)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages)
  • heart_muscle_(myocytes)
    Low:
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_glomeruli)
  • caudate_(glial_cells;_neuronal_cells)
  • tonsil_(non-germinal_center_cells;_squamous
    epithelial_cells)
  • epididymis_(glandular_cells)
  • vagina_(squamous_epithelial_cells)
  • salivary_gland_(glandular_cells)
  • cerebral_cortex_(endothelial_cells;_glial
    cells)
  • lymph_node_(non-germinal_center_cells)
  • hippocampus_(glial_cells;_neuronal_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • breast_(glandular_cells;_myoepithelial_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • pancreas_(exocrine_glandular_cells)
  • cerebellum_(cells_in_molecular_layer)
  • fallopian_tube_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(fibroblasts)
  • soft_tissue_1_(chondrocytes;_fibroblasts)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • skin_2_(epidermal_cells)
  • Artery_-_Aorta:_196.70
  • Ovary:_190.40
  • Cervix_-_Endocervix:_177.00
  • Cervix_-_Ectocervix:_173.35
  • Uterus:_170.70
  • Cells_-_Transformed_fibroblasts:_166.80
  • Fallopian_Tube:_147.30
  • Artery_-_Tibial:_142.70
  • Artery_-_Coronary:_136.20
  • Nerve_-_Tibial:_130.30
  • Bladder:_117.40
  • Colon_-_Sigmoid:_117.20
  • Prostate:_117.05
  • Esophagus_-_Gastroesophageal_Junction:_116.50
  • Thyroid:_107.70
  • Esophagus_-_Muscularis:_105.00
  • Vagina:_100.00
  • Adrenal_Gland:_87.36
  • Lung:_77.58
  • Breast_-_Mammary_Tissue:_71.19
  • Adipose_-_Subcutaneous:_69.75
  • Adipose_-_Visceral_(Omentum):_61.37
  • Skin_-_Sun_Exposed_(Lower_leg):_55.01
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_47.97
  • Kidney_-_Cortex:_47.63
  • Spleen:_47.18
  • Colon_-_Transverse:_44.55
  • Pituitary:_43.43
  • Heart_-_Atrial_Appendage:_37.84
  • Minor_Salivary_Gland:_36.18
  • Esophagus_-_Mucosa:_35.27
  • Small_Intestine_-_Terminal_Ileum:_30.18
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_21.15
  • Stomach:_21.11
  • Testis:_19.46
  • Brain_-_Anterior_cingulate_cortex_(BA24):_19.30
  • Brain_-_Substantia_nigra:_18.07
  • Brain_-_Amygdala:_17.55
  • Brain_-_Cortex:_17.46
  • Brain_-_Caudate_(basal_ganglia):_16.67
  • Brain_-_Cerebellum:_16.17
  • Brain_-_Hypothalamus:_15.61
  • Brain_-_Frontal_Cortex_(BA9):_14.73
  • Brain_-_Putamen_(basal_ganglia):_13.82
  • Brain_-_Spinal_cord_(cervical_c-1):_12.90
  • Brain_-_Hippocampus:_12.38
  • Cells_-_EBV-transformed_lymphocytes:_11.47
  • Brain_-_Cerebellar_Hemisphere:_10.55
  • Whole_Blood:_10.32
  • Heart_-_Left_Ventricle:_10.13
  • Muscle_-_Skeletal:_5.79
  • Pancreas:_4.07
  • Liver:_2.95
  • 16>NX_Q8WU58-1|F222B_HUMAN FAM222B GN=FAM222B
    MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAK
    KVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAG
    LLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQ
    ALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQ
    PMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIP
    LSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISR
    SLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGIS
    RVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAG
    PGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYF
    QPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTG
    GGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTE
    SRSLHIQHPGYR


    chromosome location: 28755978-28855232 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003676_(0.52)_nucleic_acid_binding
    GO:0003824_(0.48)_catalytic_activity
    GO:0043169_(0.32)_cation_binding
    GO:0003712_(0.20)_transcription_cofactor_activity
    GO:0003723_(0.18)_RNA_binding
    GO:0016787_(0.14)_hydrolase_activity
    GO:0016740_(0.14)_transferase_activity
    GO:0003713_(0.14)_transcription_coactivator
    activity
    GO:0044822_(0.12)_poly(A)_RNA_binding
    GO:0003677_(0.10)_DNA_binding
    GO:0016772_(0.09)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0008134_(0.07)_transcription_factor_binding
    GO:0003700_(0.07)_transcription_factor_activity,
    sequence-specific_DNA_binding
    GO:0001104_(0.07)_RNA_polymerase_II_transcription
    cofactor_activity
    GO:0044877_(0.06)_macromolecular_complex_binding
    BP:
    GO:0009987_(0.61)_cellular_process
    GO:0065007_(0.55)_biological_regulation
    GO:0050789_(0.52)_regulation_of_biological_process
    GO:0050794_(0.49)_regulation_of_cellular_process
    GO:0044699_(0.41)_single-organism_process
    GO:0019222_(0.33)_regulation_of_metabolic_process
    GO:0060255_(0.32)_regulation_of_macromolecule
    metabolic_process
    GO:0031323_(0.32)_regulation_of_cellular_metabolic
    process
    GO:0044763_(0.31)_single-organism_cellular_process
    GO:0080090_(0.30)_regulation_of_primary_metabolic
    process
    GO:0071704_(0.30)_organic_substance_metabolic
    process
    GO:0044238_(0.30)_primary_metabolic_process
    GO:0044237_(0.30)_cellular_metabolic_process
    GO:0010468_(0.30)_regulation_of_gene_expression
    GO:0051171_(0.29)_regulation_of_nitrogen_compound
    metabolic_process
    CC:
    GO:0005654_(1.00)_nucleoplasm
    UniProt annotation:
    GO:0005654_nucleoplasm

    UniProt annotation score: ◉◉○○○

    High:
  • stomach_2_(glandular_cells)
  • fallopian_tube_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • small_intestine_(glandular_cells)
  • colon_(glandular_cells)
  • gallbladder_(glandular_cells)
  • rectum_(glandular_cells)
  • duodenum_(glandular_cells)
    Medium:
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • lung_(macrophages)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_glomeruli;_cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • endometrium_2_(cells_in_endometrial_stroma;
    glandular_cells)
  • epididymis_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • vagina_(squamous_epithelial_cells)
  • cerebral_cortex_(neuronal_cells)
  • hippocampus_(glial_cells;_neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • appendix_(glandular_cells)
  • breast_(glandular_cells;_myoepithelial_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
  • cerebellum_(Purkinje_cells)
  • nasopharynx_(respiratory_epithelial_cells)
    Low:
  • cerebellum_(cells_in_granular_layer)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • placenta_(decidual_cells)
  • caudate_(neuronal_cells)
  • bone_marrow_(hematopoietic_cells)
  • adrenal_gland_(glandular_cells)
  • colon_(endothelial_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • lung_(pneumocytes)
  • oral_mucosa_(squamous_epithelial_cells)
  • cerebral_cortex_(endothelial_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • skin_2_(epidermal_cells)
  • Testis:_48.34
  • Brain_-_Cerebellar_Hemisphere:_22.43
  • Muscle_-_Skeletal:_21.75
  • Brain_-_Cerebellum:_20.01
  • Esophagus_-_Muscularis:_19.35
  • Bladder:_17.00
  • Esophagus_-_Gastroesophageal_Junction:_15.90
  • Pituitary:_15.48
  • Cervix_-_Endocervix:_15.15
  • Minor_Salivary_Gland:_14.29
  • Prostate:_14.15
  • Vagina:_13.69
  • Artery_-_Tibial:_13.63
  • Thyroid:_13.61
  • Cervix_-_Ectocervix:_12.95
  • Colon_-_Sigmoid:_12.72
  • Ovary:_12.24
  • Small_Intestine_-_Terminal_Ileum:_12.15
  • Lung:_12.14
  • Artery_-_Aorta:_12.04
  • Uterus:_12.01
  • Artery_-_Coronary:_11.92
  • Esophagus_-_Mucosa:_11.85
  • Colon_-_Transverse:_11.76
  • Breast_-_Mammary_Tissue:_11.73
  • Nerve_-_Tibial:_11.37
  • Adipose_-_Subcutaneous:_11.36
  • Cells_-_Transformed_fibroblasts:_11.08
  • Fallopian_Tube:_10.93
  • Adipose_-_Visceral_(Omentum):_10.01
  • Skin_-_Sun_Exposed_(Lower_leg):_9.92
  • Brain_-_Frontal_Cortex_(BA9):_9.73
  • Cells_-_EBV-transformed_lymphocytes:_9.47
  • Kidney_-_Cortex:_9.39
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_9.21
  • Spleen:_8.99
  • Brain_-_Spinal_cord_(cervical_c-1):_8.69
  • Brain_-_Cortex:_8.41
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_7.63
  • Brain_-_Hypothalamus:_7.60
  • Brain_-_Caudate_(basal_ganglia):_7.27
  • Stomach:_7.10
  • Brain_-_Substantia_nigra:_6.84
  • Adrenal_Gland:_6.82
  • Brain_-_Anterior_cingulate_cortex_(BA24):_6.80
  • Brain_-_Putamen_(basal_ganglia):_6.19
  • Heart_-_Atrial_Appendage:_6.19
  • Brain_-_Hippocampus:_6.04
  • Brain_-_Amygdala:_5.93
  • Heart_-_Left_Ventricle:_5.21
  • Pancreas:_4.18
  • Liver:_4.02
  • Whole_Blood:_3.59
  • 17>NX_A4FU69-1|EFCB5_HUMAN EF-hand calcium-binding domain-containing protein 5 GN=EFCAB5
    MNESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTN
    SVVEKAMDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFA
    LDETELKSKPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKK
    LPRDNLAKEWFNTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLT
    EADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQRLMKEVTEDLKIYVP
    DTICNRVSKMKENVKQNRKQRESIDKIIVKVANTRKQALQEQFDEWILDP
    KGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYI
    SSHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGK
    VGFLDRQRTLALLELFYDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGD
    MDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTST
    PSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHT
    ESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR
    ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQK
    SEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEK
    RSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQK
    IEGKSWSGEFFTCNWKMKYVTFEDEEQANLIYGNSRFTDLHSIIRNIQSC
    KEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVSETLTSFFKEGYVET
    EQEKMNALEQFSQNAFQVRQRLLLEAIFQKWDSDGSGFLDLKEVDELLYT
    YKEGMEKESMKKAKLHIQFPKPHPGHEVRLSSKQFQNYIELVVSELRGNE
    DQVLESVVEFLMNALERSHIESLRNSARRKWLHQIQCAAETSGVSLEPVY
    SETFKALMQDAEAHGNKKISAHISLLEENLLLPEKGNVLLRNVACTLDDA
    QFVLNRVLYRDMKGISFTVVDEGKPIHVPQVQYHGNIFFWNQSRNKHDYN
    GSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIRFYQGVANVFST
    AYHYVHSREHILHIVITGIGWLYDVTSSITSITTYFVEPSPAQDSDYVLR
    NMMVTGQLGLTEIHKNPPTIHRKSCIFRDFLFKCTDSSEVVLASACGETH
    IVVPLRERTGEALGVLDFNIGQNRMLLCQEYKDLQKMMKVVQVACYEILG
    EFSGEIKKKYILEIENVREVQRAGILFFRIMLLELQESIQLLNSMEFVSL
    LLYDHTLVTEPNSPQDSKSMELEANVKLVRDILKAVILFFHPELEFSSDF
    GSWDKCKFYVNKYLVNNICAFDPTAKHVEVNVQLIDEYIRDHSRTEVWKF
    GNVVIEHLYHWIHICSALMKITKQLNSGITPPLPSKTDNYMYAKMPGEGL
    QEK


    chromosome location: 29929200-30108452 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.32)_catalytic_activity
    GO:0005198_(0.19)_structural_molecule_activity
    GO:1901363_(0.17)_heterocyclic_compound_binding
    GO:0097159_(0.17)_organic_cyclic_compound_binding
    GO:0016787_(0.16)_hydrolase_activity
    GO:0016740_(0.16)_transferase_activity
    GO:0008092_(0.16)_cytoskeletal_protein_binding
    GO:0005102_(0.14)_receptor_binding
    GO:0003676_(0.14)_nucleic_acid_binding
    GO:0016887_(0.13)_ATPase_activity
    GO:0046789_(0.10)_host_cell_surface_receptor
    binding
    GO:0044877_(0.10)_macromolecular_complex_binding
    GO:0004674_(0.10)_protein_serine/threonine_kinase
    activity
    GO:0032403_(0.09)_protein_complex_binding
    GO:0003774_(0.09)_motor_activity
    BP:
    GO:0009987_(0.71)_cellular_process
    GO:0044699_(0.66)_single-organism_process
    GO:0044763_(0.50)_single-organism_cellular_process
    GO:0016043_(0.40)_cellular_component_organization
    GO:0065007_(0.38)_biological_regulation
    GO:0032502_(0.32)_developmental_process
    GO:0050789_(0.31)_regulation_of_biological_process
    GO:0044767_(0.31)_single-organism_developmental
    process
    GO:0050794_(0.30)_regulation_of_cellular_process
    GO:0048856_(0.23)_anatomical_structure_development
    GO:0008152_(0.23)_metabolic_process
    GO:0006996_(0.23)_organelle_organization
    GO:1902589_(0.21)_single-organism_organelle
    organization
    GO:0007010_(0.21)_cytoskeleton_organization
    GO:0071704_(0.20)_organic_substance_metabolic
    process
    CC:
    GO:0044464_(0.81)_cell_part
    GO:0044424_(0.74)_intracellular_part
    GO:0044422_(0.46)_organelle_part
    GO:0043226_(0.42)_organelle
    GO:0044446_(0.41)_intracellular_organelle_part
    GO:0043229_(0.40)_intracellular_organelle
    GO:0043227_(0.34)_membrane-bounded_organelle
    GO:0043231_(0.29)_intracellular_membrane-bounded
    organelle
    GO:0044430_(0.26)_cytoskeletal_part
    GO:0032991_(0.26)_macromolecular_complex
    GO:0044444_(0.25)_cytoplasmic_part
    GO:0043234_(0.24)_protein_complex
    GO:0005634_(0.22)_nucleus
    GO:0005737_(0.21)_cytoplasm
    GO:0043232_(0.17)_intracellular_non-membrane-
    bounded_organelle
    UniProt annotation:
    GO:0005509_calcium_ion_binding
    GO:0046872_metal_ion_binding

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005509_calcium_ion_binding
  • Testis:_11.52
  • Brain_-_Cerebellar_Hemisphere:_0.96
  • Brain_-_Cerebellum:_0.90
  • Brain_-_Frontal_Cortex_(BA9):_0.36
  • Nerve_-_Tibial:_0.31
  • Brain_-_Substantia_nigra:_0.30
  • Brain_-_Cortex:_0.29
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.24
  • Colon_-_Transverse:_0.23
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.21
  • Brain_-_Hypothalamus:_0.20
  • Brain_-_Spinal_cord_(cervical_c-1):_0.20
  • Brain_-_Hippocampus:_0.20
  • Thyroid:_0.19
  • Small_Intestine_-_Terminal_Ileum:_0.19
  • Bladder:_0.17
  • Brain_-_Caudate_(basal_ganglia):_0.16
  • Spleen:_0.15
  • Brain_-_Amygdala:_0.15
  • Colon_-_Sigmoid:_0.14
  • Cells_-_Transformed_fibroblasts:_0.14
  • Lung:_0.14
  • Brain_-_Putamen_(basal_ganglia):_0.13
  • Kidney_-_Cortex:_0.11
  • Skin_-_Sun_Exposed_(Lower_leg):_0.11
  • Stomach:_0.10
  • Adipose_-_Subcutaneous:_0.09
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.09
  • Esophagus_-_Gastroesophageal_Junction:_0.09
  • Cervix_-_Endocervix:_0.09
  • Esophagus_-_Muscularis:_0.09
  • Artery_-_Aorta:_0.08
  • Minor_Salivary_Gland:_0.08
  • Prostate:_0.08
  • Artery_-_Coronary:_0.08
  • Vagina:_0.08
  • Breast_-_Mammary_Tissue:_0.08
  • Uterus:_0.08
  • Cervix_-_Ectocervix:_0.08
  • Fallopian_Tube:_0.06
  • Artery_-_Tibial:_0.06
  • Cells_-_EBV-transformed_lymphocytes:_0.06
  • Pituitary:_0.06
  • Adipose_-_Visceral_(Omentum):_0.05
  • Whole_Blood:_0.05
  • Adrenal_Gland:_0.05
  • Muscle_-_Skeletal:_0.05
  • Heart_-_Atrial_Appendage:_0.04
  • Esophagus_-_Mucosa:_0.04
  • Pancreas:_0.04
  • Ovary:_0.03
  • Heart_-_Left_Ventricle:_0.03
  • Liver:_0.01
  • 18>NX_P34910-1|EVI2B_HUMAN EVI2B GN=EVI2B
    MDPKYFILILFCGHLNNTFFSKTETITTEKQSQPTLFTSSMSQVLANSQN
    TTGNPLGQPTQFSDTFSGQSISPAKVTAGQPTPAVYTSSEKPEAHTSAGQ
    PLAYNTKQPTPIANTSSQQAVFTSARQLPSARTSTTQPPKSFVYTFTQQS
    SSVQIPSRKQITVHNPSTQPTSTVKNSPRSTPGFILDTTSNKQTPQKNNY
    NSIAAILIGVLLTSMLVAIIIIVLWKCLRKPVLNDQNWAGRSPFADGETP
    DICMDNIRENEISTKRTSIISLTPWKPSKSTLLADDLEIKLFESSENIED
    SNNPKTEKIKDQVNGTSEDSADGSTVGTAVSSSDDADLPPPPPLLDLEGQ
    ESNQSDKPTMTIVSPLPNDSTSLPPSLDCLNQDCGDHKSEIIQSFPPLDS
    LNLPLPPVDFMKNQEDSNLEIQCQEFSIPPNSDQDLNESLPPPPAELL


    chromosome location: 31303766-31314112 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0005198_(0.37)_structural_molecule_activity
    GO:0003824_(0.30)_catalytic_activity
    GO:0016740_(0.17)_transferase_activity
    GO:1901363_(0.13)_heterocyclic_compound_binding
    GO:0097159_(0.13)_organic_cyclic_compound_binding
    GO:0016787_(0.12)_hydrolase_activity
    GO:0016772_(0.11)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0003676_(0.11)_nucleic_acid_binding
    GO:0008092_(0.09)_cytoskeletal_protein_binding
    GO:0005215_(0.08)_transporter_activity
    GO:0016773_(0.06)_phosphotransferase_activity,
    alcohol_group_as_acceptor
    GO:0016301_(0.06)_kinase_activity
    GO:0008190_(0.06)_eukaryotic_initiation_factor_4E
    binding
    GO:0005201_(0.06)_extracellular_matrix_structural
    constituent
    GO:0003779_(0.06)_actin_binding
    BP:
    GO:0009987_(0.62)_cellular_process
    GO:0044699_(0.48)_single-organism_process
    GO:0065007_(0.45)_biological_regulation
    GO:0051179_(0.43)_localization
    GO:0051234_(0.42)_establishment_of_localization
    GO:0006810_(0.41)_transport
    GO:0051649_(0.39)_establishment_of_localization_in
    cell
    GO:0051641_(0.39)_cellular_localization
    GO:0050789_(0.39)_regulation_of_biological_process
    GO:0050794_(0.37)_regulation_of_cellular_process
    GO:0046907_(0.37)_intracellular_transport
    GO:0044763_(0.36)_single-organism_cellular_process
    GO:0071702_(0.34)_organic_substance_transport
    GO:0051169_(0.33)_nuclear_transport
    GO:0050658_(0.32)_RNA_transport
    CC:
    GO:0005887_(1.00)_integral_component_of_plasma
    membrane
    UniProt annotation:
    Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells. {ECO:0000269|PubMed:28186500}.

    GO:2000035_regulation_of_stem_cell_division
    GO:0030854_positive_regulation_of_granulocyte
    differentiation
    GO:0061515_myeloid_cell_development
    GO:0005887_integral_component_of_plasma_membrane
    GO:0043066_negative_regulation_of_apoptotic
    process
    GO:0071157_negative_regulation_of_cell_cycle
    arrest
    GO:0045660_positive_regulation_of_neutrophil
    differentiation
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉◉◉

    NextProt annotation:
    Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells.

    GO:0030854_positive_regulation_of_granulocyte
    differentiation
    GO:0043066_negative_regulation_of_apoptotic
    process
    GO:0045660_positive_regulation_of_neutrophil
    differentiation
    GO:0061515_myeloid_cell_development
    GO:0071157_negative_regulation_of_cell_cycle
    arrest
    GO:2000035_regulation_of_stem_cell_division
    High:
  • cerebellum_(cells_in_molecular_layer;_Purkinje
    cells)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • hippocampus_(neuronal_cells)
  • caudate_(neuronal_cells)
  • spleen_(cells_in_red_pulp;_cells_in_white
    pulp)
  • bone_marrow_(hematopoietic_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells)
  • salivary_gland_(glandular_cells)
  • appendix_(lymphoid_tissue)
  • colon_(peripheral_nerve/ganglion)
  • lung_(macrophages)
  • cerebral_cortex_(neuronal_cells)
    Medium:
  • stomach_2_(glandular_cells)
  • small_intestine_(glandular_cells)
  • stomach_1_(glandular_cells)
  • liver_(hepatocytes)
  • bronchus_(respiratory_epithelial_cells)
  • testis_(cells_in_seminiferous_ducts)
  • epididymis_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • appendix_(glandular_cells)
  • colon_(glandular_cells)
  • breast_(glandular_cells;_myoepithelial_cells)
  • seminal_vesicle_(glandular_cells)
  • rectum_(glandular_cells)
  • pancreas_(exocrine_glandular_cells)
  • skin_1_(Langerhans)
  • kidney_(cells_in_tubules)
  • duodenum_(glandular_cells)
    Low:
  • placenta_(trophoblastic_cells)
  • caudate_(glial_cells)
  • fallopian_tube_(glandular_cells)
  • skin_1_(keratinocytes)
  • tonsil_(squamous_epithelial_cells)
  • skeletal_muscle_(myocytes)
  • urinary_bladder_(urothelial_cells)
  • adrenal_gland_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • colon_(endothelial_cells)
  • gallbladder_(glandular_cells)
  • lung_(pneumocytes)
  • ovary_(ovarian_stroma_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells)
  • heart_muscle_(myocytes)
  • Whole_Blood:_618.20
  • Spleen:_186.30
  • Cells_-_EBV-transformed_lymphocytes:_162.50
  • Lung:_65.21
  • Small_Intestine_-_Terminal_Ileum:_30.21
  • Cells_-_Transformed_fibroblasts:_25.41
  • Brain_-_Spinal_cord_(cervical_c-1):_19.71
  • Adipose_-_Visceral_(Omentum):_18.33
  • Adipose_-_Subcutaneous:_15.60
  • Colon_-_Transverse:_13.51
  • Minor_Salivary_Gland:_13.36
  • Artery_-_Coronary:_13.18
  • Bladder:_12.37
  • Artery_-_Aorta:_10.57
  • Nerve_-_Tibial:_9.02
  • Cervix_-_Endocervix:_8.99
  • Breast_-_Mammary_Tissue:_8.41
  • Brain_-_Substantia_nigra:_8.33
  • Fallopian_Tube:_7.94
  • Prostate:_7.57
  • Stomach:_7.00
  • Vagina:_6.57
  • Thyroid:_6.39
  • Colon_-_Sigmoid:_6.14
  • Adrenal_Gland:_5.75
  • Artery_-_Tibial:_5.56
  • Uterus:_5.52
  • Esophagus_-_Muscularis:_5.44
  • Esophagus_-_Gastroesophageal_Junction:_5.38
  • Brain_-_Hippocampus:_5.26
  • Cervix_-_Ectocervix:_5.15
  • Brain_-_Hypothalamus:_5.05
  • Esophagus_-_Mucosa:_4.86
  • Brain_-_Amygdala:_3.90
  • Skin_-_Sun_Exposed_(Lower_leg):_3.75
  • Brain_-_Caudate_(basal_ganglia):_3.66
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_3.44
  • Brain_-_Putamen_(basal_ganglia):_3.39
  • Liver:_3.35
  • Heart_-_Atrial_Appendage:_3.14
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_2.77
  • Kidney_-_Cortex:_2.70
  • Ovary:_2.58
  • Pituitary:_2.47
  • Testis:_2.44
  • Brain_-_Frontal_Cortex_(BA9):_2.37
  • Brain_-_Cortex:_2.06
  • Brain_-_Anterior_cingulate_cortex_(BA24):_1.94
  • Heart_-_Left_Ventricle:_1.46
  • Brain_-_Cerebellar_Hemisphere:_1.42
  • Pancreas:_1.29
  • Brain_-_Cerebellum:_1.12
  • Muscle_-_Skeletal:_0.85
  • 19>NX_Q96QE4-1|LR37B_HUMAN Leucine-rich repeat-containing protein 37B GN=LRRC37B
    MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSS
    RSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKE
    LDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLP
    RLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERW
    SLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPG
    PPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ
    QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEV
    TMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPP
    SDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPG
    LAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQD
    SLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEP
    DTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFE
    GLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAW
    HGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILT
    MTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEE
    ASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEI
    QLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLM
    KLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGD
    DYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA


    chromosome location: 32007872-32053504 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0005215_(0.35)_transporter_activity
    GO:0022892_(0.34)_substrate-specific_transporter
    activity
    GO:0098772_(0.28)_molecular_function_regulator
    GO:0004857_(0.27)_enzyme_inhibitor_activity
    GO:0004860_(0.26)_protein_kinase_inhibitor
    activity
    GO:0005102_(0.16)_receptor_binding
    GO:0097367_(0.15)_carbohydrate_derivative_binding
    GO:0004872_(0.15)_receptor_activity
    GO:0005539_(0.14)_glycosaminoglycan_binding
    GO:0008201_(0.13)_heparin_binding
    GO:0048495_(0.12)_Roundabout_binding
    GO:0004871_(0.12)_signal_transducer_activity
    GO:0003824_(0.12)_catalytic_activity
    GO:1901363_(0.11)_heterocyclic_compound_binding
    GO:0097159_(0.11)_organic_cyclic_compound_binding
    BP:
    GO:0065007_(0.62)_biological_regulation
    GO:0050789_(0.61)_regulation_of_biological_process
    GO:0009987_(0.60)_cellular_process
    GO:0050794_(0.59)_regulation_of_cellular_process
    GO:0044699_(0.53)_single-organism_process
    GO:0044763_(0.48)_single-organism_cellular_process
    GO:0007165_(0.45)_signal_transduction
    GO:0032502_(0.42)_developmental_process
    GO:0044767_(0.41)_single-organism_developmental
    process
    GO:0051179_(0.35)_localization
    GO:0016043_(0.35)_cellular_component_organization
    GO:0051641_(0.34)_cellular_localization
    GO:0006810_(0.34)_transport
    GO:0051649_(0.33)_establishment_of_localization_in
    cell
    GO:0008104_(0.33)_protein_localization
    CC:
    GO:0044464_(0.72)_cell_part
    GO:0044424_(0.53)_intracellular_part
    GO:0005737_(0.49)_cytoplasm
    GO:0044421_(0.30)_extracellular_region_part
    GO:0005615_(0.25)_extracellular_space
    GO:0005578_(0.23)_proteinaceous_extracellular
    matrix
    GO:0044425_(0.17)_membrane_part
    GO:0031224_(0.15)_intrinsic_component_of_membrane
    GO:0044459_(0.14)_plasma_membrane_part
    GO:0016021_(0.14)_integral_component_of_membrane
    GO:0031226_(0.13)_intrinsic_component_of_plasma
    membrane
    GO:0005887_(0.12)_integral_component_of_plasma
    membrane
    GO:0016020_(0.11)_membrane
    GO:0005886_(0.09)_plasma_membrane
    GO:0043227_(0.06)_membrane-bounded_organelle
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    Medium:
  • lymph_node_(non-germinal_center_cells)
  • placenta_(decidual_cells)
  • small_intestine_(glandular_cells)
  • stomach_1_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • bronchus_(respiratory_epithelial_cells)
  • tonsil_(non-germinal_center_cells)
  • parathyroid_gland_(glandular_cells)
  • skeletal_muscle_(myocytes)
  • vagina_(squamous_epithelial_cells)
  • salivary_gland_(glandular_cells)
  • colon_(glandular_cells)
  • gallbladder_(glandular_cells)
  • stomach_2_(glandular_cells)
  • heart_muscle_(myocytes)
  • esophagus_(squamous_epithelial_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • rectum_(glandular_cells)
  • duodenum_(glandular_cells)
    Low:
  • placenta_(trophoblastic_cells)
  • testis_(Leydig_cells)
  • seminal_vesicle_(glandular_cells)
  • tonsil_(squamous_epithelial_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • appendix_(glandular_cells)
  • colon_(peripheral_nerve/ganglion)
  • cervix,_uterine_(squamous_epithelial_cells)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages)
  • smooth_muscle_(smooth_muscle_cells)
  • pancreas_(exocrine_glandular_cells)
  • skin_1_(keratinocytes;_melanocytes)
  • kidney_(cells_in_tubules)
  • liver_(hepatocytes)
  • Testis:_27.32
  • Brain_-_Cerebellar_Hemisphere:_26.18
  • Brain_-_Cerebellum:_23.46
  • Ovary:_12.76
  • Skin_-_Sun_Exposed_(Lower_leg):_11.04
  • Pituitary:_10.86
  • Uterus:_10.43
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_10.34
  • Cervix_-_Endocervix:_9.71
  • Nerve_-_Tibial:_9.69
  • Fallopian_Tube:_8.79
  • Cervix_-_Ectocervix:_8.51
  • Vagina:_8.05
  • Bladder:_7.34
  • Brain_-_Frontal_Cortex_(BA9):_7.12
  • Lung:_7.06
  • Brain_-_Cortex:_6.87
  • Brain_-_Spinal_cord_(cervical_c-1):_6.51
  • Artery_-_Aorta:_6.49
  • Artery_-_Tibial:_6.39
  • Breast_-_Mammary_Tissue:_6.38
  • Colon_-_Sigmoid:_6.25
  • Spleen:_6.25
  • Prostate:_6.21
  • Adipose_-_Subcutaneous:_6.05
  • Artery_-_Coronary:_6.00
  • Thyroid:_5.98
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_5.89
  • Brain_-_Anterior_cingulate_cortex_(BA24):_5.79
  • Brain_-_Hippocampus:_5.66
  • Brain_-_Caudate_(basal_ganglia):_5.59
  • Small_Intestine_-_Terminal_Ileum:_5.57
  • Brain_-_Hypothalamus:_5.49
  • Brain_-_Amygdala:_5.48
  • Esophagus_-_Gastroesophageal_Junction:_5.39
  • Esophagus_-_Muscularis:_4.83
  • Cells_-_EBV-transformed_lymphocytes:_4.82
  • Minor_Salivary_Gland:_4.70
  • Brain_-_Putamen_(basal_ganglia):_4.63
  • Adipose_-_Visceral_(Omentum):_4.31
  • Brain_-_Substantia_nigra:_4.18
  • Colon_-_Transverse:_3.98
  • Esophagus_-_Mucosa:_3.86
  • Whole_Blood:_3.75
  • Cells_-_Transformed_fibroblasts:_3.49
  • Adrenal_Gland:_3.37
  • Stomach:_3.18
  • Kidney_-_Cortex:_2.01
  • Muscle_-_Skeletal:_1.77
  • Heart_-_Atrial_Appendage:_1.53
  • Pancreas:_1.45
  • Liver:_0.96
  • Heart_-_Left_Ventricle:_0.82
  • 20>NX_Q9Y2Y6-1|TMM98_HUMAN Transmembrane protein 98 GN=TMEM98
    METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLI
    GAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKI
    CHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPL
    DPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVL
    REAALASEPDKGLPGPEGFLQEQSAI


    chromosome location: 32927910-32945106 (17q11.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0046914_(0.50)_transition_metal_ion_binding
    GO:0046906_(0.50)_tetrapyrrole_binding
    GO:0016676_(0.50)_oxidoreductase_activity,_acting
    on_a_heme_group_of_donors,_oxygen_as_acceptor
    GO:0015078_(0.50)_hydrogen_ion_transmembrane
    transporter_activity
    GO:0015002_(0.50)_heme-copper_terminal_oxidase
    activity
    GO:0009055_(0.50)_electron_carrier_activity
    BP:
    GO:0098662_(0.50)_inorganic_cation_transmembrane
    transport
    GO:0046034_(0.50)_ATP_metabolic_process
    GO:0045333_(0.50)_cellular_respiration
    GO:0016310_(0.50)_phosphorylation
    GO:0015672_(0.50)_monovalent_inorganic_cation
    transport
    GO:0006818_(0.50)_hydrogen_transport
    GO:0050794_(0.35)_regulation_of_cellular_process
    CC:
    GO:0043231_(1.00)_intracellular_membrane-bounded
    organelle
    GO:0005634_(0.52)_nucleus
    GO:0005783_(0.48)_endoplasmic_reticulum
    GO:0005654_(0.07)_nucleoplasm
    GO:0005737_(0.04)_cytoplasm
    UniProt annotation:
    GO:0005783_endoplasmic_reticulum
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

  • Ovary:_109.90
  • Nerve_-_Tibial:_62.17
  • Uterus:_60.80
  • Fallopian_Tube:_51.22
  • Cells_-_Transformed_fibroblasts:_45.72
  • Cervix_-_Endocervix:_45.38
  • Artery_-_Aorta:_39.12
  • Cervix_-_Ectocervix:_36.70
  • Prostate:_35.99
  • Brain_-_Spinal_cord_(cervical_c-1):_30.36
  • Vagina:_28.84
  • Thyroid:_28.33
  • Small_Intestine_-_Terminal_Ileum:_27.55
  • Stomach:_27.26
  • Colon_-_Transverse:_26.89
  • Lung:_26.77
  • Artery_-_Coronary:_23.72
  • Adipose_-_Visceral_(Omentum):_23.69
  • Minor_Salivary_Gland:_23.41
  • Adrenal_Gland:_21.43
  • Breast_-_Mammary_Tissue:_20.57
  • Bladder:_19.68
  • Esophagus_-_Gastroesophageal_Junction:_19.62
  • Colon_-_Sigmoid:_17.97
  • Artery_-_Tibial:_17.88
  • Esophagus_-_Muscularis:_16.57
  • Pancreas:_15.51
  • Brain_-_Hippocampus:_14.59
  • Adipose_-_Subcutaneous:_14.33
  • Testis:_14.08
  • Brain_-_Putamen_(basal_ganglia):_14.08
  • Brain_-_Substantia_nigra:_13.37
  • Brain_-_Caudate_(basal_ganglia):_13.34
  • Skin_-_Sun_Exposed_(Lower_leg):_12.79
  • Pituitary:_12.41
  • Heart_-_Atrial_Appendage:_11.45
  • Brain_-_Amygdala:_11.04
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_10.78
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_10.29
  • Kidney_-_Cortex:_9.96
  • Brain_-_Hypothalamus:_9.90
  • Spleen:_9.64
  • Esophagus_-_Mucosa:_9.29
  • Brain_-_Cerebellum:_8.78
  • Brain_-_Cerebellar_Hemisphere:_8.26
  • Brain_-_Cortex:_7.10
  • Brain_-_Frontal_Cortex_(BA9):_6.37
  • Brain_-_Anterior_cingulate_cortex_(BA24):_6.33
  • Liver:_3.73
  • Heart_-_Left_Ventricle:_2.88
  • Muscle_-_Skeletal:_1.00
  • Whole_Blood:_0.11
  • Cells_-_EBV-transformed_lymphocytes:_0.10
  • 21>NX_Q8TC99-1|FNDC8_HUMAN Fibronectin type III domain-containing protein 8 GN=FNDC8
    MASEALHQVGDGEEAVLKKENFNMMNALDQLPKPFSNPKSMNRTVTTKGL
    PLASKGNLVNFLEDDTINLLKPLPVEDSDCSSDETSISAFSSTLLNPIKL
    AVTQPNSSFFAGMLEGELNKLSFSPMAKNAENEDLALGPCPCPSKSQMAT
    RGLLDLDNPELETETSSTHSESSVVVDLPDTPFIFEHTVNNSTAVISWTY
    ALGKQPVSFYQLLLQEVAKTQENELPEAKNRPWIFNKILGTTVKLMELKP
    NTCYCLSVRAANTAGVGKWCKPYKFATLATDFSSFPENYPIQITVRRKEP
    RQKIVSIGPEEMRRLEDLEYLFPC


    chromosome location: 35121579-35130732 (17q12)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003824_(0.61)_catalytic_activity
    GO:0097367_(0.51)_carbohydrate_derivative_binding
    GO:1901363_(0.50)_heterocyclic_compound_binding
    GO:0097159_(0.50)_organic_cyclic_compound_binding
    GO:0035639_(0.49)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.49)_adenyl_ribonucleotide_binding
    GO:0032550_(0.49)_purine_ribonucleoside_binding
    GO:0016740_(0.37)_transferase_activity
    GO:0004872_(0.37)_receptor_activity
    GO:0016787_(0.35)_hydrolase_activity
    GO:0004888_(0.35)_transmembrane_signaling_receptor
    activity
    GO:0004672_(0.35)_protein_kinase_activity
    GO:0008186_(0.31)_RNA-dependent_ATPase_activity
    GO:0008026_(0.31)_ATP-dependent_helicase_activity
    GO:0003724_(0.31)_RNA_helicase_activity
    BP:
    GO:0044699_(0.83)_single-organism_process
    GO:0009987_(0.83)_cellular_process
    GO:0044763_(0.77)_single-organism_cellular_process
    GO:0065007_(0.72)_biological_regulation
    GO:0050789_(0.72)_regulation_of_biological_process
    GO:0050794_(0.69)_regulation_of_cellular_process
    GO:0032502_(0.67)_developmental_process
    GO:0044767_(0.63)_single-organism_developmental
    process
    GO:0048856_(0.54)_anatomical_structure_development
    GO:0048869_(0.52)_cellular_developmental_process
    GO:0071704_(0.41)_organic_substance_metabolic
    process
    GO:0044238_(0.40)_primary_metabolic_process
    GO:0044237_(0.40)_cellular_metabolic_process
    GO:0043170_(0.40)_macromolecule_metabolic_process
    GO:0006928_(0.40)_movement_of_cell_or_subcellular
    component
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0005634_(0.96)_nucleus
    GO:0005887_(0.04)_integral_component_of_plasma
    membrane
    UniProt annotation:
    GO:0005634_nucleus

    UniProt annotation score: ◉◉○○○

    High:
  • testis_(elongated_or_late_spermatids)
    Medium:
  • testis_(round_or_early_spermatids)
    Low:
  • testis_(Leydig_cells;_pachytene_spermatocytes;
    preleptotene_spermatocytes;_sertoli_cells;
    spermatogonia)
  • Testis:_172.80
  • Cervix_-_Ectocervix:_0.37
  • Fallopian_Tube:_0.36
  • Cells_-_Transformed_fibroblasts:_0.34
  • Cells_-_EBV-transformed_lymphocytes:_0.30
  • Brain_-_Cerebellum:_0.25
  • Ovary:_0.23
  • Brain_-_Cerebellar_Hemisphere:_0.21
  • Cervix_-_Endocervix:_0.17
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.17
  • Skin_-_Sun_Exposed_(Lower_leg):_0.17
  • Spleen:_0.14
  • Brain_-_Frontal_Cortex_(BA9):_0.14
  • Brain_-_Cortex:_0.14
  • Adipose_-_Subcutaneous:_0.14
  • Prostate:_0.12
  • Nerve_-_Tibial:_0.12
  • Thyroid:_0.12
  • Esophagus_-_Mucosa:_0.11
  • Breast_-_Mammary_Tissue:_0.11
  • Uterus:_0.11
  • Small_Intestine_-_Terminal_Ileum:_0.11
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.11
  • Adipose_-_Visceral_(Omentum):_0.10
  • Vagina:_0.10
  • Bladder:_0.10
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.09
  • Lung:_0.09
  • Artery_-_Coronary:_0.08
  • Artery_-_Tibial:_0.08
  • Colon_-_Transverse:_0.08
  • Colon_-_Sigmoid:_0.07
  • Brain_-_Caudate_(basal_ganglia):_0.07
  • Minor_Salivary_Gland:_0.07
  • Brain_-_Amygdala:_0.07
  • Artery_-_Aorta:_0.07
  • Stomach:_0.06
  • Brain_-_Hypothalamus:_0.06
  • Esophagus_-_Muscularis:_0.06
  • Esophagus_-_Gastroesophageal_Junction:_0.06
  • Kidney_-_Cortex:_0.06
  • Pituitary:_0.06
  • Brain_-_Substantia_nigra:_0.06
  • Brain_-_Spinal_cord_(cervical_c-1):_0.05
  • Brain_-_Putamen_(basal_ganglia):_0.05
  • Muscle_-_Skeletal:_0.04
  • Brain_-_Hippocampus:_0.04
  • Pancreas:_0.04
  • 22>NX_Q8WW18-1|CQ050_HUMAN Uncharacterized protein C17orf50 GN=C17orf50
    MDKHGVKTPLWKKETEELRAEDAEQEEGKEGSEDEDEDNQRPLEDSATEG
    EEPPRVAEEGEGRERRSVSYCPLRQESSTQQVALLRRADSGFWGWLGPLA
    LLGGLTAPTDRKRSLPEEPCVLEIRRRPPRRGGCACCELLFCKKCRSLHS
    HPAYVAHCVLDHPDLGKAGAAGNS


    chromosome location: 35760897-35765079 (17q12)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0046982_(0.12)_protein_heterodimerization
    activity
    GO:0008601_(0.12)_protein_phosphatase_type_2A
    regulator_activity
    GO:0004722_(0.12)_protein_serine/threonine
    phosphatase_activity
    GO:0003823_(0.12)_antigen_binding
    BP:
    GO:2001241_(0.12)_positive_regulation_of_extrinsic
    apoptotic_signaling_pathway_in_absence_of_ligand
    GO:1903538_(0.12)_regulation_of_meiotic_cell_cycle
    process_involved_in_oocyte_maturation
    GO:0070262_(0.12)_peptidyl-serine
    dephosphorylation
    GO:0051754_(0.12)_meiotic_sister_chromatid
    cohesion,_centromeric
    GO:0051306_(0.12)_mitotic_sister_chromatid
    separation
    GO:0051232_(0.12)_meiotic_spindle_elongation
    GO:0042518_(0.12)_negative_regulation_of_tyrosine
    phosphorylation_of_Stat3_protein
    GO:0034047_(0.12)_regulation_of_protein
    phosphatase_type_2A_activity
    GO:0030308_(0.12)_negative_regulation_of_cell
    growth
    GO:0030155_(0.12)_regulation_of_cell_adhesion
    GO:0030111_(0.12)_regulation_of_Wnt_signaling
    pathway
    GO:0019932_(0.12)_second-messenger-mediated
    signaling
    GO:0010033_(0.12)_response_to_organic_substance
    GO:0008380_(0.12)_RNA_splicing
    GO:0007143_(0.12)_female_meiotic_division
    CC:
    GO:0044446_(1.00)_intracellular_organelle_part
    GO:0005737_(1.00)_cytoplasm
    GO:0043657_(0.90)_host_cell
    GO:0070062_(0.77)_extracellular_exosome
    GO:0016020_(0.77)_membrane
    GO:0005829_(0.77)_cytosol
    GO:0005634_(0.77)_nucleus
    GO:0044428_(0.56)_nuclear_part
    GO:0072372_(0.37)_primary_cilium
    GO:0034399_(0.37)_nuclear_periphery
    GO:0031965_(0.37)_nuclear_membrane
    GO:0015630_(0.37)_microtubule_cytoskeleton
    GO:0005739_(0.37)_mitochondrion
    GO:0005694_(0.37)_chromosome
    GO:0000775_(0.37)_chromosome,_centromeric_region

    UniProt annotation score: ◉○○○○

  • Testis:_203.00
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_1.74
  • Brain_-_Caudate_(basal_ganglia):_1.10
  • Brain_-_Cerebellar_Hemisphere:_1.07
  • Brain_-_Cerebellum:_1.04
  • Brain_-_Putamen_(basal_ganglia):_0.88
  • Brain_-_Hypothalamus:_0.82
  • Brain_-_Frontal_Cortex_(BA9):_0.77
  • Brain_-_Cortex:_0.72
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.65
  • Pituitary:_0.64
  • Nerve_-_Tibial:_0.58
  • Thyroid:_0.57
  • Brain_-_Amygdala:_0.51
  • Brain_-_Hippocampus:_0.46
  • Brain_-_Substantia_nigra:_0.41
  • Bladder:_0.37
  • Fallopian_Tube:_0.30
  • Colon_-_Transverse:_0.27
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.26
  • Lung:_0.25
  • Small_Intestine_-_Terminal_Ileum:_0.25
  • Brain_-_Spinal_cord_(cervical_c-1):_0.23
  • Cervix_-_Endocervix:_0.23
  • Esophagus_-_Muscularis:_0.22
  • Esophagus_-_Gastroesophageal_Junction:_0.21
  • Skin_-_Sun_Exposed_(Lower_leg):_0.21
  • Artery_-_Coronary:_0.17
  • Spleen:_0.17
  • Stomach:_0.17
  • Pancreas:_0.17
  • Adipose_-_Visceral_(Omentum):_0.15
  • Breast_-_Mammary_Tissue:_0.15
  • Prostate:_0.15
  • Adrenal_Gland:_0.15
  • Colon_-_Sigmoid:_0.15
  • Kidney_-_Cortex:_0.14
  • Vagina:_0.13
  • Adipose_-_Subcutaneous:_0.13
  • Esophagus_-_Mucosa:_0.13
  • Cervix_-_Ectocervix:_0.11
  • Artery_-_Tibial:_0.11
  • Minor_Salivary_Gland:_0.10
  • Uterus:_0.06
  • Ovary:_0.05
  • Artery_-_Aorta:_0.05
  • Whole_Blood:_0.04
  • Heart_-_Atrial_Appendage:_0.04
  • Muscle_-_Skeletal:_0.04
  • 23>NX_A8MV24-1|CQ098_HUMAN Uncharacterized protein C17orf98 GN=C17orf98
    MAYLSECRLRLEKGFILDGVAVSTAARAYGRSRPKLWSAIPPYNAQQDYH
    ARSYFQSHVVPPLLRKTDQDHGGTGRDGWIVDYIHIFGQGQRYLNRRNWA
    GTGHSLQQVTGHDHYNADLKPIDGFNGRFGYRRNTPALRQSTSVFGEVTH
    FPLF


    chromosome location: 38835088-38841455 (17q12)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0015926_(0.48)_glucosidase_activity
    BP:
    GO:0051275_(0.37)_beta-glucan_catabolic_process
    GO:0030243_(0.37)_cellulose_metabolic_process
    CC:
    GO:0005576_(0.75)_extracellular_region
    GO:0009507_(0.25)_chloroplast

    UniProt annotation score: ◉○○○○

  • Testis:_39.71
  • Cells_-_EBV-transformed_lymphocytes:_0.12
  • Adrenal_Gland:_0.10
  • Adipose_-_Visceral_(Omentum):_0.09
  • Thyroid:_0.09
  • Prostate:_0.09
  • Ovary:_0.09
  • Pituitary:_0.09
  • Breast_-_Mammary_Tissue:_0.08
  • Adipose_-_Subcutaneous:_0.07
  • 24>NX_Q9BQS6-1|HSPB9_HUMAN Heat shock protein beta-9 GN=HSPB9
    MQRVGNTFSNESRVASRCPSVGLAERNRVATMPVRLLRDSPAAQEDNDHA
    RDGFQMKLDAHGFAPEELVVQVDGQWLMVTGQQQLDVRDPERVSYRMSQK
    VHRKMLPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTGPSPRLGSL
    GSKASNLTR


    chromosome location: 42121431-42123352 (17q21.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0042802_(0.76)_identical_protein_binding
    GO:0042803_(0.63)_protein_homodimerization
    activity
    GO:0051082_(0.52)_unfolded_protein_binding
    GO:0005212_(0.50)_structural_constituent_of_eye
    lens
    GO:0032182_(0.39)_ubiquitin-like_protein_binding
    GO:0030291_(0.39)_protein_serine/threonine_kinase
    inhibitor_activity
    GO:0019900_(0.39)_kinase_binding
    GO:0003723_(0.37)_RNA_binding
    GO:0043169_(0.35)_cation_binding
    GO:0043130_(0.07)_ubiquitin_binding
    GO:0008426_(0.07)_protein_kinase_C_inhibitor
    activity
    GO:0005080_(0.07)_protein_kinase_C_binding
    GO:0044822_(0.05)_poly(A)_RNA_binding
    GO:0008017_(0.03)_microtubule_binding
    GO:0008022_(0.02)_protein_C-terminus_binding
    BP:
    GO:0050896_(0.82)_response_to_stimulus
    GO:0006950_(0.80)_response_to_stress
    GO:0009987_(0.75)_cellular_process
    GO:0009628_(0.71)_response_to_abiotic_stimulus
    GO:0065007_(0.63)_biological_regulation
    GO:0050789_(0.63)_regulation_of_biological_process
    GO:0044699_(0.63)_single-organism_process
    GO:0042221_(0.60)_response_to_chemical
    GO:0009408_(0.60)_response_to_heat
    GO:0050794_(0.58)_regulation_of_cellular_process
    GO:0016043_(0.56)_cellular_component_organization
    GO:0044763_(0.53)_single-organism_cellular_process
    GO:0044767_(0.52)_single-organism_developmental
    process
    GO:0048523_(0.51)_negative_regulation_of_cellular
    process
    GO:0042981_(0.51)_regulation_of_apoptotic_process
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0005634_(0.97)_nucleus
    GO:0005737_(0.96)_cytoplasm
    GO:0044422_(0.10)_organelle_part
    GO:0044444_(0.09)_cytoplasmic_part
    GO:0070062_(0.08)_extracellular_exosome
    GO:0044449_(0.07)_contractile_fiber_part
    GO:0043232_(0.07)_intracellular_non-membrane-
    bounded_organelle
    GO:0044446_(0.06)_intracellular_organelle_part
    GO:0043292_(0.06)_contractile_fiber
    GO:0016020_(0.06)_membrane
    GO:0030018_(0.05)_Z_disc
    GO:0005829_(0.05)_cytosol
    GO:0005886_(0.04)_plasma_membrane
    GO:0005654_(0.04)_nucleoplasm
    UniProt annotation:
    GO:0005737_cytoplasm
    GO:0005634_nucleus
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005515_protein_binding
  • Testis:_94.63
  • Liver:_5.04
  • Pancreas:_2.31
  • Pituitary:_2.14
  • Ovary:_2.10
  • Prostate:_1.32
  • Fallopian_Tube:_1.08
  • Colon_-_Sigmoid:_1.07
  • Spleen:_1.07
  • Uterus:_1.03
  • Bladder:_0.98
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.92
  • Esophagus_-_Gastroesophageal_Junction:_0.90
  • Brain_-_Cerebellar_Hemisphere:_0.88
  • Brain_-_Cerebellum:_0.85
  • Esophagus_-_Muscularis:_0.85
  • Stomach:_0.82
  • Cervix_-_Endocervix:_0.78
  • Kidney_-_Cortex:_0.76
  • Vagina:_0.73
  • Breast_-_Mammary_Tissue:_0.72
  • Nerve_-_Tibial:_0.71
  • Brain_-_Caudate_(basal_ganglia):_0.70
  • Thyroid:_0.70
  • Minor_Salivary_Gland:_0.69
  • Adipose_-_Visceral_(Omentum):_0.68
  • Lung:_0.68
  • Brain_-_Putamen_(basal_ganglia):_0.61
  • Small_Intestine_-_Terminal_Ileum:_0.61
  • Brain_-_Hypothalamus:_0.59
  • Adipose_-_Subcutaneous:_0.58
  • Cervix_-_Ectocervix:_0.54
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.53
  • Colon_-_Transverse:_0.53
  • Skin_-_Sun_Exposed_(Lower_leg):_0.52
  • Adrenal_Gland:_0.51
  • Brain_-_Spinal_cord_(cervical_c-1):_0.47
  • Whole_Blood:_0.44
  • Esophagus_-_Mucosa:_0.43
  • Brain_-_Frontal_Cortex_(BA9):_0.42
  • Artery_-_Coronary:_0.41
  • Brain_-_Cortex:_0.40
  • Artery_-_Aorta:_0.36
  • Cells_-_EBV-transformed_lymphocytes:_0.35
  • Brain_-_Hippocampus:_0.35
  • Brain_-_Substantia_nigra:_0.33
  • Brain_-_Amygdala:_0.29
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.29
  • Muscle_-_Skeletal:_0.25
  • Heart_-_Atrial_Appendage:_0.24
  • Artery_-_Tibial:_0.24
  • Cells_-_Transformed_fibroblasts:_0.20
  • Heart_-_Left_Ventricle:_0.14
  • 25>NX_Q96A25-1|T106A_HUMAN Transmembrane protein 106A GN=TMEM106A
    MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEG
    TADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAV
    LICLVTSSFIVFFLFPRSVIVQPAGLNSSTVAFDEADIYLNITNILNISN
    GNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLHIGPLASEQMFYAVATKIR
    DENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGN
    ASVPHQLTPHPP


    chromosome location: 43211835-43220041 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0008236_(0.36)_serine-type_peptidase_activity
    GO:0004175_(0.36)_endopeptidase_activity
    BP:
    GO:0048813_(1.00)_dendrite_morphogenesis
    GO:0032418_(1.00)_lysosome_localization
    GO:0007041_(0.93)_lysosomal_transport
    GO:0007040_(0.93)_lysosome_organization
    GO:0019538_(0.22)_protein_metabolic_process
    GO:1900006_(0.07)_positive_regulation_of_dendrite
    development
    CC:
    GO:0016020_(0.97)_membrane
    GO:0044424_(0.28)_intracellular_part
    GO:0005765_(0.26)_lysosomal_membrane
    GO:0043227_(0.13)_membrane-bounded_organelle
    GO:0070062_(0.11)_extracellular_exosome
    GO:0043231_(0.06)_intracellular_membrane-bounded
    organelle
    GO:0005764_(0.02)_lysosome
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

  • Cells_-_EBV-transformed_lymphocytes:_15.57
  • Spleen:_14.54
  • Cervix_-_Endocervix:_9.18
  • Ovary:_8.45
  • Lung:_8.28
  • Cervix_-_Ectocervix:_8.23
  • Thyroid:_8.00
  • Kidney_-_Cortex:_7.20
  • Testis:_7.16
  • Uterus:_7.11
  • Artery_-_Aorta:_6.58
  • Nerve_-_Tibial:_6.52
  • Fallopian_Tube:_6.50
  • Adipose_-_Subcutaneous:_6.14
  • Artery_-_Coronary:_6.06
  • Adipose_-_Visceral_(Omentum):_5.77
  • Breast_-_Mammary_Tissue:_5.08
  • Small_Intestine_-_Terminal_Ileum:_4.79
  • Prostate:_4.74
  • Cells_-_Transformed_fibroblasts:_4.29
  • Whole_Blood:_4.14
  • Vagina:_4.09
  • Minor_Salivary_Gland:_4.07
  • Bladder:_3.97
  • Artery_-_Tibial:_3.87
  • Colon_-_Sigmoid:_3.50
  • Esophagus_-_Gastroesophageal_Junction:_3.36
  • Colon_-_Transverse:_3.28
  • Adrenal_Gland:_3.10
  • Esophagus_-_Muscularis:_3.04
  • Pituitary:_2.81
  • Stomach:_2.76
  • Brain_-_Spinal_cord_(cervical_c-1):_2.70
  • Pancreas:_2.05
  • Heart_-_Atrial_Appendage:_1.75
  • Skin_-_Sun_Exposed_(Lower_leg):_1.60
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_1.32
  • Esophagus_-_Mucosa:_1.27
  • Brain_-_Substantia_nigra:_1.25
  • Liver:_1.20
  • Brain_-_Hypothalamus:_1.02
  • Brain_-_Caudate_(basal_ganglia):_0.82
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.79
  • Heart_-_Left_Ventricle:_0.77
  • Brain_-_Hippocampus:_0.77
  • Brain_-_Amygdala:_0.69
  • Brain_-_Putamen_(basal_ganglia):_0.59
  • Brain_-_Frontal_Cortex_(BA9):_0.53
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.52
  • Brain_-_Cortex:_0.51
  • Muscle_-_Skeletal:_0.51
  • Brain_-_Cerebellum:_0.44
  • Brain_-_Cerebellar_Hemisphere:_0.42
  • 26>NX_B2RV13-1|CF97D_HUMAN Uncharacterized protein C17orf105 GN=C17orf105
    MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKPTVDTKP
    PVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNE
    YFSKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRR
    YIRNTTRYLLSQNE


    chromosome location: 43780435-43787612 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003824_(0.95)_catalytic_activity
    GO:0016740_(0.44)_transferase_activity
    GO:0004842_(0.41)_ubiquitin-protein_transferase
    activity
    GO:0004185_(0.36)_serine-type_carboxypeptidase
    activity
    GO:0004181_(0.36)_metallocarboxypeptidase_activity
    GO:0003755_(0.19)_peptidyl-prolyl_cis-trans
    isomerase_activity
    GO:0043565_(0.09)_sequence-specific_DNA_binding
    GO:0030412_(0.09)_formimidoyltetrahydrofolate
    cyclodeaminase_activity
    GO:0003690_(0.09)_double-stranded_DNA_binding
    GO:0030409_(0.05)_glutamate_formimidoyltransferase
    activity
    GO:0019903_(0.05)_protein_phosphatase_binding
    GO:0019215_(0.05)_intermediate_filament_binding
    GO:0008017_(0.05)_microtubule_binding
    GO:0005542_(0.05)_folic_acid_binding
    GO:0005102_(0.05)_receptor_binding
    BP:
    GO:0044238_(1.00)_primary_metabolic_process
    GO:0044237_(1.00)_cellular_metabolic_process
    GO:0043170_(1.00)_macromolecule_metabolic_process
    GO:0019538_(0.94)_protein_metabolic_process
    GO:0044260_(0.58)_cellular_macromolecule_metabolic
    process
    GO:0034641_(0.53)_cellular_nitrogen_compound
    metabolic_process
    GO:0006464_(0.51)_cellular_protein_modification
    process
    GO:0042787_(0.49)_protein_ubiquitination_involved
    in_ubiquitin-dependent_protein_catabolic_process
    GO:1901564_(0.47)_organonitrogen_compound
    metabolic_process
    GO:0043603_(0.47)_cellular_amide_metabolic_process
    GO:0016485_(0.44)_protein_processing
    GO:0006518_(0.44)_peptide_metabolic_process
    GO:1901360_(0.10)_organic_cyclic_compound
    metabolic_process
    GO:0046483_(0.10)_heterocycle_metabolic_process
    GO:0042592_(0.10)_homeostatic_process
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.90)_intracellular_part
    GO:0043231_(0.88)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.88)_cytoplasm
    GO:0005634_(0.81)_nucleus
    GO:0005829_(0.76)_cytosol
    GO:0044446_(0.65)_intracellular_organelle_part
    GO:0044428_(0.54)_nuclear_part
    GO:0016020_(0.51)_membrane
    GO:0005654_(0.51)_nucleoplasm
    GO:0044421_(0.48)_extracellular_region_part
    GO:0044454_(0.45)_nuclear_chromosome_part
    GO:0032991_(0.45)_macromolecular_complex
    GO:0005615_(0.44)_extracellular_space
    GO:0000790_(0.41)_nuclear_chromatin

    UniProt annotation score: ◉◉○○○

    High:
  • testis_(cells_in_seminiferous_ducts)
  • Testis:_36.54
  • Brain_-_Cerebellar_Hemisphere:_0.30
  • Brain_-_Cerebellum:_0.28
  • Spleen:_0.12
  • Brain_-_Frontal_Cortex_(BA9):_0.09
  • Brain_-_Cortex:_0.08
  • Nerve_-_Tibial:_0.06
  • Artery_-_Coronary:_0.06
  • Artery_-_Aorta:_0.06
  • Pituitary:_0.06
  • Brain_-_Hypothalamus:_0.06
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.05
  • Skin_-_Sun_Exposed_(Lower_leg):_0.05
  • Cervix_-_Ectocervix:_0.05
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.05
  • Brain_-_Spinal_cord_(cervical_c-1):_0.05
  • Adipose_-_Subcutaneous:_0.05
  • Brain_-_Substantia_nigra:_0.05
  • Brain_-_Amygdala:_0.05
  • Lung:_0.04
  • Breast_-_Mammary_Tissue:_0.04
  • Thyroid:_0.04
  • Artery_-_Tibial:_0.04
  • Cervix_-_Endocervix:_0.04
  • Bladder:_0.04
  • Brain_-_Hippocampus:_0.04
  • Fallopian_Tube:_0.04
  • Brain_-_Caudate_(basal_ganglia):_0.04
  • Cells_-_Transformed_fibroblasts:_0.03
  • Brain_-_Putamen_(basal_ganglia):_0.03
  • Uterus:_0.03
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.03
  • Prostate:_0.03
  • Colon_-_Sigmoid:_0.03
  • Adrenal_Gland:_0.03
  • Muscle_-_Skeletal:_0.03
  • Adipose_-_Visceral_(Omentum):_0.02
  • Esophagus_-_Gastroesophageal_Junction:_0.02
  • Esophagus_-_Muscularis:_0.02
  • Vagina:_0.02
  • Liver:_0.02
  • Minor_Salivary_Gland:_0.02
  • Small_Intestine_-_Terminal_Ileum:_0.02
  • Whole_Blood:_0.02
  • Kidney_-_Cortex:_0.02
  • Cells_-_EBV-transformed_lymphocytes:_0.02
  • Ovary:_0.02
  • Stomach:_0.02
  • Esophagus_-_Mucosa:_0.01
  • Heart_-_Atrial_Appendage:_0.01
  • Colon_-_Transverse:_0.01
  • Heart_-_Left_Ventricle:_0.01
  • 27>NX_Q3MHD2-1|LSM12_HUMAN Protein LSM12 homolog GN=LSM12
    MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKP
    NHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLS
    QAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVEN
    CKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS


    chromosome location: 44034635-44067619 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003723_(0.59)_RNA_binding
    GO:0003729_(0.13)_mRNA_binding
    GO:0046872_(0.11)_metal_ion_binding
    GO:0008810_(0.06)_cellulase_activity
    BP:
    GO:0009987_(1.00)_cellular_process
    GO:0044238_(0.80)_primary_metabolic_process
    GO:0044237_(0.80)_cellular_metabolic_process
    GO:0043170_(0.80)_macromolecule_metabolic_process
    GO:0090304_(0.79)_nucleic_acid_metabolic_process
    GO:0044260_(0.74)_cellular_macromolecule_metabolic
    process
    GO:0016070_(0.73)_RNA_metabolic_process
    GO:0022618_(0.39)_ribonucleoprotein_complex
    assembly
    GO:0000387_(0.32)_spliceosomal_snRNP_assembly
    GO:0051170_(0.11)_nuclear_import
    GO:0000398_(0.11)_mRNA_splicing,_via_spliceosome
    GO:0033962_(0.07)_cytoplasmic_mRNA_processing_body
    assembly
    GO:0031087_(0.07)_deadenylation-independent
    decapping_of_nuclear-transcribed_mRNA
    GO:0030245_(0.05)_cellulose_catabolic_process
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0044444_(0.75)_cytoplasmic_part
    GO:0043229_(0.64)_intracellular_organelle
    GO:0032991_(0.60)_macromolecular_complex
    GO:0005576_(0.55)_extracellular_region
    GO:0005829_(0.47)_cytosol
    GO:0005634_(0.33)_nucleus
    GO:0036464_(0.31)_cytoplasmic_ribonucleoprotein
    granule
    GO:0034719_(0.29)_SMN-Sm_protein_complex
    GO:0032797_(0.29)_SMN_complex
    GO:0044422_(0.26)_organelle_part
    GO:0005737_(0.26)_cytoplasm
    GO:0010494_(0.25)_cytoplasmic_stress_granule
    GO:0005840_(0.25)_ribosome
    GO:0016604_(0.19)_nuclear_body

    UniProt annotation score: ◉◉◉○○

    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells;
    peripheral_nerve/ganglion)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • breast_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • cerebral_cortex_(neuronal_cells)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • bronchus_(respiratory_epithelial_cells)
  • skeletal_muscle_(myocytes)
  • urinary_bladder_(urothelial_cells)
  • small_intestine_(glandular_cells)
  • liver_(hepatocytes)
  • rectum_(glandular_cells)
  • cervix,_uterine_(glandular_cells)
  • duodenum_(glandular_cells)
  • cerebellum_(cells_in_molecular_layer;_Purkinje
    cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • nasopharynx_(respiratory_epithelial_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_2_(epidermal_cells)
    Medium:
  • cerebellum_(cells_in_granular_layer)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • testis_(Leydig_cells)
  • caudate_(neuronal_cells)
  • fallopian_tube_(glandular_cells)
  • prostate_(glandular_cells)
  • vagina_(squamous_epithelial_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • lung_(macrophages;_pneumocytes)
  • heart_muscle_(myocytes)
  • ovary_(follicle_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • cerebral_cortex_(endothelial_cells)
  • kidney_(cells_in_glomeruli)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
    Low:
  • spleen_(cells_in_white_pulp)
  • bone_marrow_(hematopoietic_cells)
  • parathyroid_gland_(glandular_cells)
  • endometrium_1_(cells_in_endometrial_stroma)
  • liver_(bile_duct_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • ovary_(ovarian_stroma_cells)
  • cerebral_cortex_(glial_cells;_neuropil)
  • cervix,_uterine_(squamous_epithelial_cells)
  • breast_(myoepithelial_cells)
  • Cells_-_EBV-transformed_lymphocytes:_16.88
  • Cells_-_Transformed_fibroblasts:_16.69
  • Testis:_13.62
  • Esophagus_-_Mucosa:_7.91
  • Uterus:_7.03
  • Lung:_6.80
  • Fallopian_Tube:_6.73
  • Vagina:_6.67
  • Bladder:_6.56
  • Cervix_-_Ectocervix:_6.50
  • Cervix_-_Endocervix:_6.42
  • Brain_-_Cerebellar_Hemisphere:_6.34
  • Adipose_-_Visceral_(Omentum):_6.34
  • Thyroid:_6.29
  • Adrenal_Gland:_6.21
  • Breast_-_Mammary_Tissue:_6.11
  • Ovary:_5.97
  • Adipose_-_Subcutaneous:_5.96
  • Esophagus_-_Muscularis:_5.96
  • Prostate:_5.93
  • Colon_-_Sigmoid:_5.91
  • Artery_-_Coronary:_5.88
  • Artery_-_Aorta:_5.87
  • Artery_-_Tibial:_5.85
  • Spleen:_5.68
  • Esophagus_-_Gastroesophageal_Junction:_5.62
  • Nerve_-_Tibial:_5.58
  • Muscle_-_Skeletal:_5.54
  • Minor_Salivary_Gland:_5.49
  • Colon_-_Transverse:_5.46
  • Brain_-_Spinal_cord_(cervical_c-1):_5.25
  • Brain_-_Cerebellum:_5.07
  • Small_Intestine_-_Terminal_Ileum:_5.05
  • Skin_-_Sun_Exposed_(Lower_leg):_5.04
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_5.00
  • Brain_-_Frontal_Cortex_(BA9):_4.97
  • Pituitary:_4.89
  • Stomach:_4.69
  • Whole_Blood:_4.65
  • Brain_-_Hypothalamus:_4.58
  • Brain_-_Anterior_cingulate_cortex_(BA24):_3.88
  • Heart_-_Atrial_Appendage:_3.80
  • Kidney_-_Cortex:_3.61
  • Brain_-_Substantia_nigra:_3.55
  • Brain_-_Cortex:_3.50
  • Liver:_3.46
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_3.44
  • Pancreas:_3.33
  • Brain_-_Amygdala:_3.29
  • Brain_-_Hippocampus:_3.14
  • Brain_-_Caudate_(basal_ganglia):_3.04
  • Heart_-_Left_Ventricle:_2.72
  • Brain_-_Putamen_(basal_ganglia):_2.44
  • 28>NX_Q8N3J3-1|CQ053_HUMAN Uncharacterized protein C17orf53 GN=C17orf53
    MACSLQKLFAVEEEFEDEDFLSAVEDAENRFTGSLPVNAGRLRPVSSRPQ
    ETVQAQSSRLLLLHPTAPSEALGLPDLDLCLPASSTPSADSRPSCIGAAP
    LRPVSTSSSWIGNQRRVTVTEVLRETARPQSSALHPLLTFESQQQQVGGF
    EGPEQDEFDKVLASMELEEPGMELECGVSSEAIPILPAQQREGSVLAKKA
    RVVDLSGSCQKGPVPAIHKAGIMSAQDESLDPVIQCRTPRPPLRPGAVGH
    LPVPTALTVPTQQLHWEVCPQRSPVQALQPLQAARGTIQSSPQNRFPCQP
    FQSPSSWLSGKAHLPRPRTPNSSCSTPSRTSSGLFPRIPLQPQAPVSSIG
    SPVGTPKGPQGALQTPIVTNHLVQLVTAASRTPQQPTHPSTRAKTRRFPG
    PAGILPHQQSGRSLEDIMVSAPQTPTHGALAKFQTEIVASSQASVEEDFG
    RGPWLTMKSTLGLDERDPSCFLCTYSIVMVLRKQAALKQLPRNKVPNMAV
    MIKSLTRSTMDASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQI
    GVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSFLKPSQPFPKDSGSFQHDV
    AAKPEEGFRTAQNLEAEASPEEELPEADDLDGLLSELPEDFFCGTSS


    chromosome location: 44141906-44162476 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.54)_catalytic_activity
    GO:0016787_(0.43)_hydrolase_activity
    GO:0004175_(0.37)_endopeptidase_activity
    GO:0004252_(0.36)_serine-type_endopeptidase
    activity
    GO:1901363_(0.18)_heterocyclic_compound_binding
    GO:0097159_(0.18)_organic_cyclic_compound_binding
    GO:0016740_(0.17)_transferase_activity
    GO:0003676_(0.16)_nucleic_acid_binding
    GO:0016772_(0.12)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0005215_(0.11)_transporter_activity
    GO:0015075_(0.09)_ion_transmembrane_transporter
    activity
    GO:0004672_(0.09)_protein_kinase_activity
    GO:0003723_(0.09)_RNA_binding
    GO:0019899_(0.08)_enzyme_binding
    GO:0005261_(0.08)_cation_channel_activity
    BP:
    GO:0009987_(0.80)_cellular_process
    GO:0065007_(0.75)_biological_regulation
    GO:0050789_(0.72)_regulation_of_biological_process
    GO:0044699_(0.71)_single-organism_process
    GO:0050794_(0.70)_regulation_of_cellular_process
    GO:0044763_(0.67)_single-organism_cellular_process
    GO:0071704_(0.62)_organic_substance_metabolic
    process
    GO:0044237_(0.62)_cellular_metabolic_process
    GO:0016043_(0.62)_cellular_component_organization
    GO:0044260_(0.61)_cellular_macromolecule_metabolic
    process
    GO:0048518_(0.60)_positive_regulation_of
    biological_process
    GO:0051179_(0.58)_localization
    GO:0048519_(0.58)_negative_regulation_of
    biological_process
    GO:0065008_(0.57)_regulation_of_biological_quality
    GO:0048523_(0.57)_negative_regulation_of_cellular
    process
    CC:
    GO:0005576_(0.91)_extracellular_region
    GO:0044464_(0.90)_cell_part
    GO:0044424_(0.77)_intracellular_part
    GO:0044421_(0.70)_extracellular_region_part
    GO:0043226_(0.70)_organelle
    GO:0005615_(0.67)_extracellular_space
    GO:0043227_(0.66)_membrane-bounded_organelle
    GO:0031982_(0.55)_vesicle
    GO:0031988_(0.54)_membrane-bounded_vesicle
    GO:0070062_(0.53)_extracellular_exosome
    GO:0016020_(0.53)_membrane
    GO:0044422_(0.48)_organelle_part
    GO:0044446_(0.47)_intracellular_organelle_part
    GO:0044444_(0.42)_cytoplasmic_part
    GO:0043229_(0.39)_intracellular_organelle

    UniProt annotation score: ◉◉○○○

  • Testis:_29.93
  • Cells_-_EBV-transformed_lymphocytes:_14.84
  • Esophagus_-_Mucosa:_3.92
  • Skin_-_Sun_Exposed_(Lower_leg):_3.21
  • Esophagus_-_Muscularis:_3.14
  • Cells_-_Transformed_fibroblasts:_2.75
  • Adipose_-_Subcutaneous:_2.71
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_2.66
  • Breast_-_Mammary_Tissue:_2.61
  • Spleen:_2.40
  • Nerve_-_Tibial:_2.33
  • Vagina:_2.31
  • Adipose_-_Visceral_(Omentum):_1.98
  • Ovary:_1.85
  • Cervix_-_Endocervix:_1.76
  • Cervix_-_Ectocervix:_1.74
  • Uterus:_1.62
  • Brain_-_Cerebellum:_1.57
  • Fallopian_Tube:_1.57
  • Brain_-_Cerebellar_Hemisphere:_1.54
  • Prostate:_1.51
  • Small_Intestine_-_Terminal_Ileum:_1.50
  • Bladder:_1.34
  • Colon_-_Transverse:_1.29
  • Lung:_1.28
  • Whole_Blood:_1.17
  • Minor_Salivary_Gland:_1.15
  • Esophagus_-_Gastroesophageal_Junction:_0.94
  • Artery_-_Tibial:_0.93
  • Pituitary:_0.92
  • Artery_-_Coronary:_0.90
  • Colon_-_Sigmoid:_0.87
  • Thyroid:_0.84
  • Adrenal_Gland:_0.78
  • Stomach:_0.76
  • Heart_-_Atrial_Appendage:_0.62
  • Brain_-_Hypothalamus:_0.60
  • Artery_-_Aorta:_0.57
  • Brain_-_Spinal_cord_(cervical_c-1):_0.49
  • Kidney_-_Cortex:_0.48
  • Brain_-_Cortex:_0.46
  • Muscle_-_Skeletal:_0.44
  • Brain_-_Frontal_Cortex_(BA9):_0.43
  • Heart_-_Left_Ventricle:_0.42
  • Liver:_0.42
  • Brain_-_Substantia_nigra:_0.32
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.32
  • Brain_-_Hippocampus:_0.30
  • Brain_-_Amygdala:_0.29
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.29
  • Pancreas:_0.25
  • Brain_-_Caudate_(basal_ganglia):_0.24
  • Brain_-_Putamen_(basal_ganglia):_0.20
  • 29>NX_Q71RG4-1|TMUB2_HUMAN Transmembrane and ubiquitin-like domain-containing protein 2 GN=TMUB2
    MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALV
    LAWLSTYVADSGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELP
    HPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDIQGLPKRQAGA
    GSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALK
    SKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVP
    GPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPA
    TVSLVGVTVFFSFLVFGMYGR


    chromosome location: 44186970-44191731 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:1990841_(0.41)_promoter-specific_chromatin
    binding
    GO:0051718_(0.41)_DNA
    (cytosine-5-)-methyltransferase_activity,_acting
    on_CpG_substrates
    GO:0045322_(0.41)_unmethylated_CpG_binding
    GO:0042826_(0.41)_histone_deacetylase_binding
    GO:0030331_(0.41)_estrogen_receptor_binding
    GO:0019904_(0.41)_protein_domain_specific_binding
    GO:0008327_(0.41)_methyl-CpG_binding
    GO:0008270_(0.41)_zinc_ion_binding
    GO:0003723_(0.41)_RNA_binding
    GO:0003690_(0.41)_double-stranded_DNA_binding
    BP:
    GO:0009987_(0.92)_cellular_process
    GO:0044260_(0.90)_cellular_macromolecule_metabolic
    process
    GO:0044238_(0.90)_primary_metabolic_process
    GO:0019538_(0.78)_protein_metabolic_process
    GO:0019941_(0.63)_modification-dependent_protein
    catabolic_process
    GO:0006511_(0.62)_ubiquitin-dependent_protein
    catabolic_process
    GO:0065007_(0.57)_biological_regulation
    GO:0043412_(0.56)_macromolecule_modification
    GO:0050789_(0.55)_regulation_of_biological_process
    GO:0071840_(0.54)_cellular_component_organization
    or_biogenesis
    GO:0050794_(0.54)_regulation_of_cellular_process
    GO:0016043_(0.53)_cellular_component_organization
    GO:0048519_(0.49)_negative_regulation_of
    biological_process
    GO:0080090_(0.48)_regulation_of_primary_metabolic
    process
    GO:0060255_(0.48)_regulation_of_macromolecule
    metabolic_process
    CC:
    GO:0005634_(1.00)_nucleus
    GO:0044446_(0.91)_intracellular_organelle_part
    GO:0044428_(0.89)_nuclear_part
    GO:0005737_(0.81)_cytoplasm
    GO:0005654_(0.79)_nucleoplasm
    GO:0032991_(0.67)_macromolecular_complex
    GO:0043234_(0.64)_protein_complex
    GO:0044427_(0.44)_chromosomal_part
    GO:0043025_(0.44)_neuronal_cell_body
    GO:0005721_(0.43)_pericentric_heterochromatin
    GO:0005657_(0.43)_replication_fork
    GO:0044444_(0.39)_cytoplasmic_part
    GO:0005829_(0.27)_cytosol
    GO:0044445_(0.13)_cytosolic_part
    GO:0016020_(0.11)_membrane
    UniProt annotation:
    GO:0005515_protein_binding
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005515_protein_binding
    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells;
    peripheral_nerve/ganglion)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • caudate_(neuronal_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • heart_muscle_(myocytes)
  • duodenum_(glandular_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • skeletal_muscle_(myocytes)
  • appendix_(glandular_cells)
  • liver_(hepatocytes)
  • rectum_(glandular_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • pancreas_(exocrine_glandular_cells)
  • placenta_(trophoblastic_cells)
  • fallopian_tube_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(fibroblasts)
  • small_intestine_(glandular_cells)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages)
  • skin_1_(fibroblasts;_Langerhans;_melanocytes)
  • breast_(glandular_cells)
    Medium:
  • lung_(pneumocytes)
  • kidney_(cells_in_glomeruli)
  • liver_(bile_duct_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • thyroid_gland_(glandular_cells)
  • endometrium_1_(cells_in_endometrial_stroma)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • vagina_(squamous_epithelial_cells)
  • cerebral_cortex_(glial_cells;_neuronal_cells;
    neuropil)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • hippocampus_(neuronal_cells)
  • urinary_bladder_(urothelial_cells)
  • appendix_(lymphoid_tissue)
  • breast_(myoepithelial_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells)
  • pancreas_(islets_of_Langerhans)
  • cerebellum_(cells_in_granular_layer;_Purkinje
    cells)
  • spleen_(cells_in_red_pulp;_cells_in_white
    pulp)
  • soft_tissue_1_(fibroblasts;_peripheral_nerve)
  • soft_tissue_2_(adipocytes;_chondrocytes)
  • ovary_(ovarian_stroma_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(keratinocytes)
  • skin_2_(epidermal_cells)
    Low:
  • cerebellum_(cells_in_molecular_layer)
  • hippocampus_(glial_cells)
  • caudate_(glial_cells)
  • soft_tissue_1_(adipocytes)
  • breast_(adipocytes)
  • cerebral_cortex_(endothelial_cells)
  • Testis:_66.97
  • Spleen:_65.14
  • Thyroid:_64.86
  • Cervix_-_Endocervix:_60.76
  • Prostate:_53.27
  • Brain_-_Cerebellum:_52.39
  • Brain_-_Cerebellar_Hemisphere:_51.70
  • Uterus:_49.60
  • Nerve_-_Tibial:_47.60
  • Bladder:_47.01
  • Fallopian_Tube:_46.91
  • Artery_-_Tibial:_46.59
  • Ovary:_46.54
  • Whole_Blood:_46.43
  • Cervix_-_Ectocervix:_44.28
  • Lung:_44.10
  • Artery_-_Aorta:_43.17
  • Artery_-_Coronary:_43.08
  • Vagina:_42.80
  • Breast_-_Mammary_Tissue:_41.12
  • Colon_-_Sigmoid:_40.81
  • Cells_-_Transformed_fibroblasts:_40.20
  • Adipose_-_Subcutaneous:_40.17
  • Esophagus_-_Gastroesophageal_Junction:_39.79
  • Esophagus_-_Muscularis:_39.21
  • Pituitary:_39.13
  • Small_Intestine_-_Terminal_Ileum:_39.02
  • Minor_Salivary_Gland:_38.84
  • Colon_-_Transverse:_38.81
  • Skin_-_Sun_Exposed_(Lower_leg):_36.38
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_35.60
  • Adipose_-_Visceral_(Omentum):_34.73
  • Esophagus_-_Mucosa:_33.80
  • Stomach:_32.60
  • Adrenal_Gland:_32.27
  • Brain_-_Cortex:_27.66
  • Cells_-_EBV-transformed_lymphocytes:_27.56
  • Brain_-_Frontal_Cortex_(BA9):_26.92
  • Kidney_-_Cortex:_24.72
  • Brain_-_Spinal_cord_(cervical_c-1):_20.10
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_18.90
  • Brain_-_Hypothalamus:_18.27
  • Brain_-_Anterior_cingulate_cortex_(BA24):_17.97
  • Brain_-_Caudate_(basal_ganglia):_16.79
  • Pancreas:_16.54
  • Heart_-_Atrial_Appendage:_15.94
  • Liver:_15.32
  • Brain_-_Hippocampus:_15.07
  • Brain_-_Substantia_nigra:_15.04
  • Muscle_-_Skeletal:_14.46
  • Brain_-_Amygdala:_14.13
  • Brain_-_Putamen_(basal_ganglia):_13.66
  • Heart_-_Left_Ventricle:_11.81
  • 30>NX_A8MVW0-1|F1712_HUMAN FAM171A2 GN=FAM171A2
    MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVS
    GELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARP
    GFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARS
    QPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSG
    NGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSI
    PAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGL
    VTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQ
    HRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHS
    AFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGP
    GGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLL
    SQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLG
    GEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGG
    GEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPH
    PRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARR
    RPAREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLT
    PLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAE
    VGDEAGDKKSPWQRREERPLMVFNVK


    chromosome location: 44353215-44363875 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:1901363_(0.58)_heterocyclic_compound_binding
    GO:0097159_(0.58)_organic_cyclic_compound_binding
    GO:0003676_(0.56)_nucleic_acid_binding
    GO:0019899_(0.54)_enzyme_binding
    GO:0017016_(0.52)_Ras_GTPase_binding
    GO:0022892_(0.47)_substrate-specific_transporter
    activity
    GO:0003824_(0.27)_catalytic_activity
    GO:0016740_(0.16)_transferase_activity
    GO:0022857_(0.10)_transmembrane_transporter
    activity
    GO:0008092_(0.10)_cytoskeletal_protein_binding
    GO:0022891_(0.09)_substrate-specific_transmembrane
    transporter_activity
    GO:0016772_(0.09)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0005198_(0.09)_structural_molecule_activity
    GO:0016787_(0.08)_hydrolase_activity
    GO:0005261_(0.08)_cation_channel_activity
    BP:
    GO:0009987_(0.74)_cellular_process
    GO:0065007_(0.66)_biological_regulation
    GO:0050789_(0.60)_regulation_of_biological_process
    GO:0050794_(0.58)_regulation_of_cellular_process
    GO:0016043_(0.52)_cellular_component_organization
    GO:0051179_(0.49)_localization
    GO:0071704_(0.47)_organic_substance_metabolic
    process
    GO:0044238_(0.47)_primary_metabolic_process
    GO:0044699_(0.46)_single-organism_process
    GO:0043170_(0.46)_macromolecule_metabolic_process
    GO:0006810_(0.46)_transport
    GO:0060255_(0.42)_regulation_of_macromolecule
    metabolic_process
    GO:0006996_(0.42)_organelle_organization
    GO:0080090_(0.41)_regulation_of_primary_metabolic
    process
    GO:0031323_(0.41)_regulation_of_cellular_metabolic
    process
    CC:
    GO:0043226_(0.90)_organelle
    GO:0044464_(0.89)_cell_part
    GO:0043227_(0.88)_membrane-bounded_organelle
    GO:0044424_(0.87)_intracellular_part
    GO:0044422_(0.75)_organelle_part
    GO:0043229_(0.75)_intracellular_organelle
    GO:0044446_(0.74)_intracellular_organelle_part
    GO:0043231_(0.73)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.66)_cytoplasm
    GO:0032991_(0.65)_macromolecular_complex
    GO:0044444_(0.64)_cytoplasmic_part
    GO:0043234_(0.64)_protein_complex
    GO:0031982_(0.53)_vesicle
    GO:0031988_(0.52)_membrane-bounded_vesicle
    GO:0044421_(0.51)_extracellular_region_part
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

  • Brain_-_Cerebellar_Hemisphere:_35.12
  • Brain_-_Cerebellum:_35.00
  • Brain_-_Frontal_Cortex_(BA9):_25.35
  • Brain_-_Cortex:_24.67
  • Brain_-_Anterior_cingulate_cortex_(BA24):_16.97
  • Pituitary:_16.93
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_14.72
  • Cervix_-_Endocervix:_11.60
  • Brain_-_Hypothalamus:_11.41
  • Brain_-_Caudate_(basal_ganglia):_10.03
  • Brain_-_Amygdala:_9.89
  • Brain_-_Hippocampus:_8.84
  • Brain_-_Putamen_(basal_ganglia):_7.61
  • Ovary:_7.54
  • Uterus:_6.81
  • Cervix_-_Ectocervix:_6.51
  • Vagina:_3.94
  • Thyroid:_3.59
  • Brain_-_Substantia_nigra:_3.51
  • Esophagus_-_Mucosa:_3.14
  • Fallopian_Tube:_2.85
  • Brain_-_Spinal_cord_(cervical_c-1):_2.28
  • Nerve_-_Tibial:_1.87
  • Prostate:_1.74
  • Cells_-_Transformed_fibroblasts:_1.57
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_1.26
  • Testis:_1.20
  • Colon_-_Sigmoid:_1.20
  • Adipose_-_Visceral_(Omentum):_1.16
  • Lung:_1.08
  • Skin_-_Sun_Exposed_(Lower_leg):_0.99
  • Kidney_-_Cortex:_0.88
  • Breast_-_Mammary_Tissue:_0.81
  • Esophagus_-_Gastroesophageal_Junction:_0.76
  • Adipose_-_Subcutaneous:_0.76
  • Heart_-_Atrial_Appendage:_0.71
  • Esophagus_-_Muscularis:_0.67
  • Small_Intestine_-_Terminal_Ileum:_0.65
  • Minor_Salivary_Gland:_0.63
  • Colon_-_Transverse:_0.57
  • Spleen:_0.54
  • Adrenal_Gland:_0.53
  • Bladder:_0.48
  • Cells_-_EBV-transformed_lymphocytes:_0.38
  • Stomach:_0.36
  • Artery_-_Coronary:_0.32
  • Heart_-_Left_Ventricle:_0.27
  • Pancreas:_0.20
  • Artery_-_Aorta:_0.17
  • Artery_-_Tibial:_0.13
  • Liver:_0.13
  • Whole_Blood:_0.10
  • Muscle_-_Skeletal:_0.10
  • 31>NX_Q96MW1-1|CCD43_HUMAN Coiled-coil domain-containing protein 43 GN=CCDC43
    MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQE
    EEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEV
    QAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDD
    SGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRE
    RDKLAKQERKEKEKKRTQRGERKR


    chromosome location: 44673069-44689779 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0008565_(0.13)_protein_transporter_activity
    GO:0008139_(0.13)_nuclear_localization_sequence
    binding
    GO:0005509_(0.10)_calcium_ion_binding
    GO:0005198_(0.10)_structural_molecule_activity
    GO:0004871_(0.10)_signal_transducer_activity
    GO:0004435_(0.10)_phosphatidylinositol
    phospholipase_C_activity
    GO:0098641_(0.05)_cadherin_binding_involved_in
    cell-cell_adhesion
    GO:0005516_(0.05)_calmodulin_binding
    BP:
    GO:0044699_(0.77)_single-organism_process
    GO:0009987_(0.53)_cellular_process
    GO:0006810_(0.44)_transport
    GO:0046907_(0.41)_intracellular_transport
    GO:0044763_(0.39)_single-organism_cellular_process
    GO:0006886_(0.38)_intracellular_protein_transport
    GO:0006606_(0.35)_protein_import_into_nucleus
    GO:0050794_(0.32)_regulation_of_cellular_process
    GO:0006607_(0.32)_NLS-bearing_protein_import_into
    nucleus
    GO:0016043_(0.29)_cellular_component_organization
    GO:0071704_(0.25)_organic_substance_metabolic
    process
    GO:0044238_(0.25)_primary_metabolic_process
    GO:0006928_(0.25)_movement_of_cell_or_subcellular
    component
    GO:0032502_(0.23)_developmental_process
    GO:0080090_(0.20)_regulation_of_primary_metabolic
    process
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.97)_intracellular_part
    GO:0044422_(0.88)_organelle_part
    GO:0044446_(0.84)_intracellular_organelle_part
    GO:0044444_(0.71)_cytoplasmic_part
    GO:0005829_(0.70)_cytosol
    GO:0044428_(0.66)_nuclear_part
    GO:0043226_(0.56)_organelle
    GO:0005737_(0.53)_cytoplasm
    GO:0005654_(0.51)_nucleoplasm
    GO:0016020_(0.50)_membrane
    GO:0043229_(0.49)_intracellular_organelle
    GO:0043227_(0.46)_membrane-bounded_organelle
    GO:0032991_(0.46)_macromolecular_complex
    GO:0043231_(0.44)_intracellular_membrane-bounded
    organelle
    UniProt annotation:
    GO:0005829_cytosol
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005515_protein_binding
    Medium:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(glandular_cells)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • caudate_(neuronal_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • duodenum_(glandular_cells)
  • cerebral_cortex_(neuronal_cells;_neuropil)
  • vagina_(squamous_epithelial_cells)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • breast_(glandular_cells;_myoepithelial_cells)
  • rectum_(glandular_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • pancreas_(exocrine_glandular_cells)
  • cerebellum_(Purkinje_cells)
  • fallopian_tube_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(fibroblasts;_peripheral_nerve)
  • small_intestine_(glandular_cells)
  • soft_tissue_1_(fibroblasts)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_2_(epidermal_cells)
    Low:
  • cerebellum_(cells_in_molecular_layer)
  • hippocampus_(neuronal_cells)
  • caudate_(glial_cells)
  • spleen_(cells_in_red_pulp)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • skeletal_muscle_(myocytes)
  • colon_(endothelial_cells)
  • heart_muscle_(myocytes)
  • soft_tissue_1_(peripheral_nerve)
  • lung_(macrophages)
  • ovary_(follicle_cells)
  • cerebral_cortex_(endothelial_cells;_glial
    cells)
  • kidney_(cells_in_glomeruli)
  • pancreas_(islets_of_Langerhans)
  • Muscle_-_Skeletal:_27.17
  • Cells_-_Transformed_fibroblasts:_26.08
  • Cells_-_EBV-transformed_lymphocytes:_26.07
  • Brain_-_Cerebellar_Hemisphere:_24.00
  • Brain_-_Cerebellum:_18.54
  • Nerve_-_Tibial:_18.03
  • Brain_-_Spinal_cord_(cervical_c-1):_17.89
  • Brain_-_Frontal_Cortex_(BA9):_15.66
  • Thyroid:_14.89
  • Uterus:_14.86
  • Fallopian_Tube:_14.42
  • Cervix_-_Ectocervix:_14.17
  • Vagina:_14.12
  • Esophagus_-_Mucosa:_14.08
  • Cervix_-_Endocervix:_13.91
  • Lung:_13.67
  • Prostate:_13.16
  • Artery_-_Coronary:_13.11
  • Breast_-_Mammary_Tissue:_13.10
  • Testis:_12.93
  • Adrenal_Gland:_12.88
  • Adipose_-_Subcutaneous:_12.87
  • Spleen:_12.79
  • Adipose_-_Visceral_(Omentum):_12.58
  • Bladder:_12.54
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_12.27
  • Ovary:_12.27
  • Colon_-_Sigmoid:_12.19
  • Skin_-_Sun_Exposed_(Lower_leg):_11.97
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_11.91
  • Brain_-_Anterior_cingulate_cortex_(BA24):_11.82
  • Minor_Salivary_Gland:_11.78
  • Brain_-_Cortex:_11.76
  • Artery_-_Tibial:_11.65
  • Brain_-_Hippocampus:_11.29
  • Brain_-_Amygdala:_11.23
  • Esophagus_-_Muscularis:_11.03
  • Artery_-_Aorta:_11.01
  • Small_Intestine_-_Terminal_Ileum:_10.96
  • Brain_-_Hypothalamus:_10.85
  • Brain_-_Caudate_(basal_ganglia):_10.84
  • Esophagus_-_Gastroesophageal_Junction:_10.76
  • Colon_-_Transverse:_10.73
  • Brain_-_Substantia_nigra:_10.01
  • Heart_-_Left_Ventricle:_9.47
  • Stomach:_9.44
  • Brain_-_Putamen_(basal_ganglia):_9.42
  • Heart_-_Atrial_Appendage:_9.29
  • Kidney_-_Cortex:_8.87
  • Pituitary:_7.79
  • Pancreas:_6.02
  • Liver:_3.87
  • Whole_Blood:_2.59
  • 32>NX_Q9P298-1|HIG1B_HUMAN HIG1 domain family member 1B GN=HIGD1B
    MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLR
    SRGSTKMSIHLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK


    chromosome location: 44846353-44850480 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0016740_(0.79)_transferase_activity
    GO:0061630_(0.71)_ubiquitin_protein_ligase
    activity
    GO:1901265_(0.28)_nucleoside_phosphate_binding
    GO:0036094_(0.28)_small_molecule_binding
    GO:0034061_(0.28)_DNA_polymerase_activity
    GO:0004527_(0.28)_exonuclease_activity
    BP:
    GO:0009987_(0.57)_cellular_process
    GO:0065007_(0.51)_biological_regulation
    GO:0043066_(0.32)_negative_regulation_of_apoptotic
    process
    GO:0043623_(0.31)_cellular_protein_complex
    assembly
    GO:0044699_(0.29)_single-organism_process
    GO:0044260_(0.26)_cellular_macromolecule_metabolic
    process
    GO:0044238_(0.26)_primary_metabolic_process
    GO:0033617_(0.25)_mitochondrial_respiratory_chain
    complex_IV_assembly
    GO:0034654_(0.24)_nucleobase-containing_compound
    biosynthetic_process
    GO:0034645_(0.24)_cellular_macromolecule
    biosynthetic_process
    GO:0006259_(0.24)_DNA_metabolic_process
    GO:0055070_(0.19)_copper_ion_homeostasis
    GO:0048149_(0.19)_behavioral_response_to_ethanol
    GO:0090201_(0.10)_negative_regulation_of_release
    of_cytochrome_c_from_mitochondria
    GO:0071902_(0.10)_positive_regulation_of_protein
    serine/threonine_kinase_activity
    CC:
    GO:0044464_(0.95)_cell_part
    GO:0044424_(0.94)_intracellular_part
    GO:0032991_(0.90)_macromolecular_complex
    GO:0044446_(0.88)_intracellular_organelle_part
    GO:0043234_(0.88)_protein_complex
    GO:0043229_(0.86)_intracellular_organelle
    GO:0044444_(0.85)_cytoplasmic_part
    GO:0043231_(0.80)_intracellular_membrane-bounded
    organelle
    GO:0005634_(0.71)_nucleus
    GO:0044429_(0.53)_mitochondrial_part
    GO:0005737_(0.46)_cytoplasm
    GO:0044428_(0.45)_nuclear_part
    GO:0044427_(0.45)_chromosomal_part
    GO:0044425_(0.43)_membrane_part
    GO:0005739_(0.42)_mitochondrion
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

  • Lung:_40.38
  • Brain_-_Substantia_nigra:_21.38
  • Brain_-_Putamen_(basal_ganglia):_20.96
  • Brain_-_Caudate_(basal_ganglia):_19.61
  • Brain_-_Frontal_Cortex_(BA9):_17.02
  • Brain_-_Anterior_cingulate_cortex_(BA24):_16.71
  • Brain_-_Hippocampus:_15.77
  • Brain_-_Cortex:_15.70
  • Brain_-_Hypothalamus:_15.58
  • Heart_-_Left_Ventricle:_15.38
  • Brain_-_Amygdala:_15.24
  • Uterus:_14.89
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_13.81
  • Brain_-_Spinal_cord_(cervical_c-1):_11.42
  • Prostate:_10.93
  • Adipose_-_Visceral_(Omentum):_10.42
  • Brain_-_Cerebellum:_9.27
  • Brain_-_Cerebellar_Hemisphere:_8.86
  • Esophagus_-_Muscularis:_8.42
  • Breast_-_Mammary_Tissue:_8.37
  • Esophagus_-_Gastroesophageal_Junction:_7.51
  • Cervix_-_Endocervix:_6.25
  • Nerve_-_Tibial:_6.01
  • Fallopian_Tube:_5.65
  • Muscle_-_Skeletal:_5.64
  • Thyroid:_4.90
  • Vagina:_4.53
  • Colon_-_Sigmoid:_4.38
  • Esophagus_-_Mucosa:_4.24
  • Small_Intestine_-_Terminal_Ileum:_3.92
  • Ovary:_3.49
  • Cervix_-_Ectocervix:_3.06
  • Adipose_-_Subcutaneous:_2.96
  • Heart_-_Atrial_Appendage:_2.79
  • Bladder:_2.67
  • Stomach:_2.65
  • Artery_-_Coronary:_2.30
  • Colon_-_Transverse:_2.17
  • Testis:_2.07
  • Minor_Salivary_Gland:_1.47
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_1.42
  • Pancreas:_1.34
  • Kidney_-_Cortex:_1.19
  • Skin_-_Sun_Exposed_(Lower_leg):_1.12
  • Pituitary:_0.95
  • Artery_-_Aorta:_0.71
  • Artery_-_Tibial:_0.60
  • Spleen:_0.32
  • Adrenal_Gland:_0.29
  • Liver:_0.23
  • Cells_-_EBV-transformed_lymphocytes:_0.17
  • Cells_-_Transformed_fibroblasts:_0.12
  • Whole_Blood:_0.07
  • 33>NX_A6NFU0-1|F187A_HUMAN Ig-like V-type domain-containing protein FAM187A GN=FAM187A
    MHLALTTVLLWAWGLQAFEIVEKENIFQRTPCPAFLMFENAAYLADMSFE
    LPCHCKPEEVPAVVWFYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDML
    TRFSIRMFSLLVFRAQSEDSGLYFCGTRKGDYFYAYDVDIQNSEGMVATF
    QDKGQEPFADEYYGHLHVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDL
    SPRYLKAVPDVVSCGSRAVPRKLRTKARDHTPEVLVRSCLVPCEKTKTIR
    EGVLAIINYVSKVGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAW
    DKDRQHLYRTQYLKGVNRSMRVFIDHGNQLHIRFTQLDDRGIYYCWRQGV
    LVAGFRLGVTSHGHYPASFSDPETRSAVELTLIGYLLITAVFVTIHFCRC
    CCYLFHCCPSFSP


    chromosome location: 44899712-44905390 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • Human Protein Atlas
  • MF:
    GO:0004872_(0.55)_receptor_activity
    GO:0042802_(0.50)_identical_protein_binding
    GO:0046983_(0.48)_protein_dimerization_activity
    GO:0004888_(0.46)_transmembrane_signaling_receptor
    activity
    GO:0097367_(0.42)_carbohydrate_derivative_binding
    GO:0098632_(0.30)_protein_binding_involved_in
    cell-cell_adhesion
    GO:0042803_(0.21)_protein_homodimerization
    activity
    GO:0005102_(0.21)_receptor_binding
    GO:0050839_(0.14)_cell_adhesion_molecule_binding
    GO:0003824_(0.14)_catalytic_activity
    GO:0016740_(0.12)_transferase_activity
    GO:0004672_(0.11)_protein_kinase_activity
    GO:0005198_(0.09)_structural_molecule_activity
    GO:0003823_(0.09)_antigen_binding
    GO:0008046_(0.08)_axon_guidance_receptor_activity
    BP:
    GO:0044699_(0.82)_single-organism_process
    GO:0009987_(0.80)_cellular_process
    GO:0044763_(0.79)_single-organism_cellular_process
    GO:0065007_(0.65)_biological_regulation
    GO:0050789_(0.65)_regulation_of_biological_process
    GO:0006928_(0.64)_movement_of_cell_or_subcellular
    component
    GO:0050794_(0.63)_regulation_of_cellular_process
    GO:0032502_(0.63)_developmental_process
    GO:0044767_(0.60)_single-organism_developmental
    process
    GO:0007411_(0.59)_axon_guidance
    GO:0048856_(0.55)_anatomical_structure_development
    GO:0048869_(0.53)_cellular_developmental_process
    GO:0016043_(0.53)_cellular_component_organization
    GO:0051239_(0.52)_regulation_of_multicellular
    organismal_process
    GO:0007155_(0.52)_cell_adhesion
    CC:
    GO:0044464_(0.98)_cell_part
    GO:0031224_(0.93)_intrinsic_component_of_membrane
    GO:0016020_(0.92)_membrane
    GO:0016021_(0.82)_integral_component_of_membrane
    GO:0005886_(0.71)_plasma_membrane
    GO:0044459_(0.66)_plasma_membrane_part
    GO:0097458_(0.59)_neuron_part
    GO:0044421_(0.55)_extracellular_region_part
    GO:0043005_(0.53)_neuron_projection
    GO:0030424_(0.52)_axon
    GO:0031226_(0.51)_intrinsic_component_of_plasma
    membrane
    GO:0005887_(0.50)_integral_component_of_plasma
    membrane
    GO:0044424_(0.48)_intracellular_part
    GO:0030054_(0.43)_cell_junction
    GO:0043025_(0.40)_neuronal_cell_body
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

    High:
  • heart_muscle_(myocytes)
  • smooth_muscle_(smooth_muscle_cells)
    Medium:
  • testis_(Leydig_cells)
  • cerebral_cortex_(neuronal_cells)
  • skeletal_muscle_(myocytes)
  • caudate_(neuronal_cells)
    Low:
  • cerebellum_(Purkinje_cells)
  • placenta_(trophoblastic_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • hippocampus_(neuronal_cells)
  • thyroid_gland_(glandular_cells)
  • small_intestine_(glandular_cells)
  • colon_(glandular_cells)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • duodenum_(glandular_cells)
  • kidney_(cells_in_tubules)
  • breast_(myoepithelial_cells)
  • 34>NX_A6NMS7-1|L37A1_HUMAN Leucine-rich repeat-containing protein 37A GN=LRRC37A
    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT
    SNPLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ
    ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL
    KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR
    VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL
    EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
    PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP
    MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHH
    QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE
    PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA
    EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG
    FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
    PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ
    VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL
    PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD
    LGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA
    QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ
    RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
    LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT
    ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV
    PLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSAC
    LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINL
    SGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS
    LAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
    AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP
    FSKGTPSTSSPAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVH
    ARKKYRFHKTRSHVTHRTTKVKKSPKVRKKSYLSRLMLANRLPFSAAKSL
    INSPSQGAFSSLGDLSPQENPFLEVSALSEHFIEKNNTKHTTARNAFEEN
    DFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNV
    GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
    LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIEN
    YINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFC
    LIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWF
    KDLYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP


    chromosome location: 46292733-46337794 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0098772_(0.27)_molecular_function_regulator
    GO:0030234_(0.26)_enzyme_regulator_activity
    GO:0004860_(0.25)_protein_kinase_inhibitor
    activity
    GO:0005102_(0.16)_receptor_binding
    GO:0097367_(0.15)_carbohydrate_derivative_binding
    GO:0004872_(0.15)_receptor_activity
    GO:0005539_(0.14)_glycosaminoglycan_binding
    GO:0008201_(0.13)_heparin_binding
    GO:0097159_(0.12)_organic_cyclic_compound_binding
    GO:0003824_(0.12)_catalytic_activity
    GO:0048495_(0.11)_Roundabout_binding
    GO:0038023_(0.11)_signaling_receptor_activity
    GO:0003676_(0.11)_nucleic_acid_binding
    GO:0004888_(0.08)_transmembrane_signaling_receptor
    activity
    GO:0003723_(0.08)_RNA_binding
    BP:
    GO:0065007_(0.61)_biological_regulation
    GO:0050789_(0.59)_regulation_of_biological_process
    GO:0009987_(0.59)_cellular_process
    GO:0050794_(0.58)_regulation_of_cellular_process
    GO:0044699_(0.53)_single-organism_process
    GO:0044763_(0.47)_single-organism_cellular_process
    GO:0032502_(0.44)_developmental_process
    GO:0007165_(0.44)_signal_transduction
    GO:0044767_(0.42)_single-organism_developmental
    process
    GO:0016043_(0.35)_cellular_component_organization
    GO:0048583_(0.32)_regulation_of_response_to
    stimulus
    GO:0007166_(0.30)_cell_surface_receptor_signaling
    pathway
    GO:0019222_(0.29)_regulation_of_metabolic_process
    GO:0009653_(0.29)_anatomical_structure
    morphogenesis
    GO:0031323_(0.28)_regulation_of_cellular_metabolic
    process
    CC:
    GO:0044464_(0.78)_cell_part
    GO:0044424_(0.59)_intracellular_part
    GO:0005737_(0.38)_cytoplasm
    GO:0044421_(0.24)_extracellular_region_part
    GO:0044425_(0.19)_membrane_part
    GO:0043226_(0.19)_organelle
    GO:0031012_(0.19)_extracellular_matrix
    GO:0005615_(0.18)_extracellular_space
    GO:0043229_(0.16)_intracellular_organelle
    GO:0005578_(0.16)_proteinaceous_extracellular
    matrix
    GO:0044459_(0.15)_plasma_membrane_part
    GO:0044444_(0.15)_cytoplasmic_part
    GO:0043227_(0.15)_membrane-bounded_organelle
    GO:0032991_(0.15)_macromolecular_complex
    GO:0031224_(0.15)_intrinsic_component_of_membrane
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    High:
  • testis_(elongated_or_late_spermatids;_round_or
    early_spermatids)
    Low:
  • testis_(pachytene_spermatocytes;_preleptotene
    spermatocytes)
  • Testis:_2.25
  • Brain_-_Cerebellar_Hemisphere:_1.21
  • Pituitary:_1.17
  • Brain_-_Cerebellum:_1.05
  • Cervix_-_Endocervix:_1.02
  • Prostate:_1.01
  • Thyroid:_0.94
  • Uterus:_0.87
  • Nerve_-_Tibial:_0.86
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.86
  • Spleen:_0.80
  • Skin_-_Sun_Exposed_(Lower_leg):_0.79
  • Vagina:_0.74
  • Lung:_0.72
  • Ovary:_0.72
  • Bladder:_0.70
  • Cervix_-_Ectocervix:_0.67
  • Colon_-_Sigmoid:_0.65
  • Cells_-_EBV-transformed_lymphocytes:_0.61
  • Esophagus_-_Gastroesophageal_Junction:_0.60
  • Adipose_-_Subcutaneous:_0.58
  • Minor_Salivary_Gland:_0.57
  • Breast_-_Mammary_Tissue:_0.57
  • Artery_-_Tibial:_0.57
  • Artery_-_Coronary:_0.57
  • Artery_-_Aorta:_0.56
  • Small_Intestine_-_Terminal_Ileum:_0.56
  • Esophagus_-_Muscularis:_0.55
  • Brain_-_Cortex:_0.55
  • Brain_-_Frontal_Cortex_(BA9):_0.54
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.53
  • Adipose_-_Visceral_(Omentum):_0.50
  • Esophagus_-_Mucosa:_0.50
  • Brain_-_Caudate_(basal_ganglia):_0.48
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.48
  • Colon_-_Transverse:_0.47
  • Brain_-_Spinal_cord_(cervical_c-1):_0.44
  • Brain_-_Hypothalamus:_0.43
  • Brain_-_Hippocampus:_0.42
  • Fallopian_Tube:_0.41
  • Brain_-_Amygdala:_0.40
  • Stomach:_0.39
  • Whole_Blood:_0.38
  • Cells_-_Transformed_fibroblasts:_0.38
  • Adrenal_Gland:_0.38
  • Brain_-_Putamen_(basal_ganglia):_0.36
  • Kidney_-_Cortex:_0.32
  • Brain_-_Substantia_nigra:_0.30
  • Muscle_-_Skeletal:_0.28
  • Pancreas:_0.24
  • Heart_-_Atrial_Appendage:_0.23
  • Liver:_0.22
  • Heart_-_Left_Ventricle:_0.12
  • 35>NX_A6NM11-1|L37A2_HUMAN Leucine-rich repeat-containing protein 37A2 GN=LRRC37A2
    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT
    SNPLGPPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ
    ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL
    KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR
    VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL
    EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
    PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP
    MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHH
    QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE
    PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA
    EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG
    FTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
    PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ
    VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL
    PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD
    LGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA
    QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ
    RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
    LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT
    ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV
    PLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSAC
    LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINL
    SGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS
    LAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
    AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP
    FSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVH
    ARKKYRFHKTRSHVTHRTPKVKKSPKVRKKSYLSRLMLANRLPFSAAKSL
    INSPSQGAFSSLGDLSPQENPFLEVSAPSEHFIENNNTKHTTARNAFEEN
    DFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQTETKWEYNNV
    GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
    LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIEN
    YINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFC
    LIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWF
    KDMYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP


    chromosome location: 46511511-46555650 (17q21.31)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0098772_(0.27)_molecular_function_regulator
    GO:0004857_(0.26)_enzyme_inhibitor_activity
    GO:0004860_(0.25)_protein_kinase_inhibitor
    activity
    GO:0097367_(0.16)_carbohydrate_derivative_binding
    GO:0005102_(0.16)_receptor_binding
    GO:0004872_(0.16)_receptor_activity
    GO:0005539_(0.14)_glycosaminoglycan_binding
    GO:0008201_(0.13)_heparin_binding
    GO:0048495_(0.12)_Roundabout_binding
    GO:1901363_(0.11)_heterocyclic_compound_binding
    GO:0097159_(0.11)_organic_cyclic_compound_binding
    GO:0038023_(0.11)_signaling_receptor_activity
    GO:0003824_(0.11)_catalytic_activity
    GO:0003676_(0.10)_nucleic_acid_binding
    GO:0004888_(0.08)_transmembrane_signaling_receptor
    activity
    BP:
    GO:0065007_(0.61)_biological_regulation
    GO:0050789_(0.60)_regulation_of_biological_process
    GO:0009987_(0.59)_cellular_process
    GO:0050794_(0.58)_regulation_of_cellular_process
    GO:0044699_(0.53)_single-organism_process
    GO:0044763_(0.47)_single-organism_cellular_process
    GO:0007165_(0.45)_signal_transduction
    GO:0032502_(0.44)_developmental_process
    GO:0044767_(0.42)_single-organism_developmental
    process
    GO:0016043_(0.35)_cellular_component_organization
    GO:0048583_(0.32)_regulation_of_response_to
    stimulus
    GO:0007166_(0.30)_cell_surface_receptor_signaling
    pathway
    GO:0031323_(0.29)_regulation_of_cellular_metabolic
    process
    GO:0009653_(0.29)_anatomical_structure
    morphogenesis
    GO:0080090_(0.28)_regulation_of_primary_metabolic
    process
    CC:
    GO:0044464_(0.78)_cell_part
    GO:0044424_(0.58)_intracellular_part
    GO:0005737_(0.37)_cytoplasm
    GO:0044421_(0.24)_extracellular_region_part
    GO:0044425_(0.19)_membrane_part
    GO:0043226_(0.19)_organelle
    GO:0031012_(0.19)_extracellular_matrix
    GO:0005615_(0.18)_extracellular_space
    GO:0005578_(0.17)_proteinaceous_extracellular
    matrix
    GO:0044459_(0.16)_plasma_membrane_part
    GO:0043229_(0.16)_intracellular_organelle
    GO:0044444_(0.15)_cytoplasmic_part
    GO:0043227_(0.15)_membrane-bounded_organelle
    GO:0031224_(0.15)_intrinsic_component_of_membrane
    GO:0016020_(0.15)_membrane
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    High:
  • testis_(elongated_or_late_spermatids;_round_or
    early_spermatids)
    Low:
  • testis_(pachytene_spermatocytes;_preleptotene
    spermatocytes)
  • Testis:_12.15
  • Pituitary:_7.56
  • Brain_-_Cerebellar_Hemisphere:_7.45
  • Brain_-_Cerebellum:_7.00
  • Prostate:_5.92
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_5.70
  • Thyroid:_5.67
  • Uterus:_5.59
  • Skin_-_Sun_Exposed_(Lower_leg):_5.47
  • Nerve_-_Tibial:_5.36
  • Vagina:_5.28
  • Cervix_-_Ectocervix:_5.08
  • Ovary:_5.00
  • Bladder:_4.96
  • Spleen:_4.55
  • Cervix_-_Endocervix:_4.54
  • Lung:_4.52
  • Colon_-_Sigmoid:_3.93
  • Artery_-_Aorta:_3.72
  • Breast_-_Mammary_Tissue:_3.70
  • Brain_-_Cortex:_3.62
  • Esophagus_-_Gastroesophageal_Junction:_3.62
  • Adipose_-_Subcutaneous:_3.60
  • Artery_-_Tibial:_3.59
  • Cells_-_EBV-transformed_lymphocytes:_3.58
  • Artery_-_Coronary:_3.57
  • Minor_Salivary_Gland:_3.55
  • Brain_-_Frontal_Cortex_(BA9):_3.44
  • Esophagus_-_Muscularis:_3.38
  • Small_Intestine_-_Terminal_Ileum:_3.32
  • Esophagus_-_Mucosa:_3.15
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_3.11
  • Adipose_-_Visceral_(Omentum):_3.10
  • Fallopian_Tube:_3.07
  • Brain_-_Spinal_cord_(cervical_c-1):_2.92
  • Colon_-_Transverse:_2.83
  • Brain_-_Hypothalamus:_2.68
  • Adrenal_Gland:_2.54
  • Brain_-_Caudate_(basal_ganglia):_2.54
  • Whole_Blood:_2.48
  • Brain_-_Hippocampus:_2.48
  • Cells_-_Transformed_fibroblasts:_2.48
  • Stomach:_2.37
  • Brain_-_Anterior_cingulate_cortex_(BA24):_2.24
  • Brain_-_Amygdala:_2.17
  • Muscle_-_Skeletal:_2.01
  • Brain_-_Substantia_nigra:_1.83
  • Brain_-_Putamen_(basal_ganglia):_1.78
  • Kidney_-_Cortex:_1.77
  • Pancreas:_1.50
  • Heart_-_Atrial_Appendage:_1.45
  • Liver:_1.20
  • Heart_-_Left_Ventricle:_0.84
  • 36>NX_Q9BU68-1|PR15L_HUMAN Proline-rich protein 15-like protein GN=PRR15L
    MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSD
    FNTRLEKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGR
    SSK


    chromosome location: 47951967-47957878 (17q21.32)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0044877_(0.31)_macromolecular_complex_binding
    GO:0005524_(0.31)_ATP_binding
    GO:0004672_(0.31)_protein_kinase_activity
    BP:
    GO:0018108_(0.42)_peptidyl-tyrosine
    phosphorylation
    GO:0008283_(0.42)_cell_proliferation
    GO:0006955_(0.42)_immune_response
    GO:0006952_(0.42)_defense_response
    GO:2001236_(0.31)_regulation_of_extrinsic
    apoptotic_signaling_pathway
    GO:2001234_(0.31)_negative_regulation_of_apoptotic
    signaling_pathway
    GO:0043068_(0.31)_positive_regulation_of
    programmed_cell_death
    GO:0022610_(0.31)_biological_adhesion
    CC:
    GO:0044464_(0.95)_cell_part
    GO:0044424_(0.89)_intracellular_part
    GO:0005737_(0.84)_cytoplasm
    GO:0016020_(0.74)_membrane
    GO:0044425_(0.68)_membrane_part
    GO:0044444_(0.63)_cytoplasmic_part
    GO:0044459_(0.58)_plasma_membrane_part
    GO:0043226_(0.58)_organelle
    GO:0005829_(0.58)_cytosol
    GO:0043227_(0.53)_membrane-bounded_organelle
    GO:0043231_(0.47)_intracellular_membrane-bounded
    organelle
    GO:0098590_(0.37)_plasma_membrane_region
    GO:0005886_(0.37)_plasma_membrane
    GO:0044446_(0.32)_intracellular_organelle_part
    GO:0043234_(0.32)_protein_complex

    UniProt annotation score: ◉○○○○

    High:
  • cerebellum_(Purkinje_cells)
  • lymph_node_(non-germinal_center_cells)
  • small_intestine_(glandular_cells)
  • placenta_(decidual_cells)
  • seminal_vesicle_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • bronchus_(respiratory_epithelial_cells)
  • tonsil_(non-germinal_center_cells)
  • testis_(Leydig_cells)
  • endometrium_2_(glandular_cells)
  • appendix_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells)
  • gallbladder_(glandular_cells)
  • stomach_2_(glandular_cells)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages)
  • rectum_(glandular_cells)
  • skin_2_(epidermal_cells)
  • kidney_(cells_in_glomeruli;_cells_in_tubules)
  • duodenum_(glandular_cells)
    Medium:
  • stomach_1_(glandular_cells)
  • colon_(peripheral_nerve/ganglion)
  • smooth_muscle_(smooth_muscle_cells)
  • testis_(cells_in_seminiferous_ducts)
  • tonsil_(germinal_center_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • heart_muscle_(myocytes)
  • cerebral_cortex_(endothelial_cells)
  • lymph_node_(germinal_center_cells)
  • parathyroid_gland_(glandular_cells)
  • skeletal_muscle_(myocytes)
  • urinary_bladder_(urothelial_cells)
  • appendix_(lymphoid_tissue)
  • liver_(bile_duct_cells)
  • prostate_(glandular_cells)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
  • placenta_(trophoblastic_cells)
  • fallopian_tube_(glandular_cells)
  • spleen_(cells_in_red_pulp)
  • soft_tissue_1_(adipocytes;_fibroblasts)
  • soft_tissue_2_(adipocytes;_fibroblasts)
  • ovary_(follicle_cells;_ovarian_stroma_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • breast_(glandular_cells;_myoepithelial_cells)
    Low:
  • cerebellum_(cells_in_granular_layer;_cells_in
    molecular_layer)
  • hippocampus_(glial_cells;_neuronal_cells)
  • caudate_(glial_cells)
  • spleen_(cells_in_white_pulp)
  • soft_tissue_1_(peripheral_nerve)
  • soft_tissue_2_(peripheral_nerve)
  • tonsil_(squamous_epithelial_cells)
  • endometrium_2_(cells_in_endometrial_stroma)
  • salivary_gland_(glandular_cells)
  • lung_(pneumocytes)
  • breast_(adipocytes)
  • esophagus_(squamous_epithelial_cells)
  • cerebral_cortex_(glial_cells;_neuronal_cells;
    neuropil)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • Stomach:_125.00
  • Thyroid:_107.95
  • Small_Intestine_-_Terminal_Ileum:_100.50
  • Colon_-_Transverse:_100.50
  • Minor_Salivary_Gland:_84.31
  • Pancreas:_72.31
  • Lung:_42.94
  • Prostate:_30.08
  • Kidney_-_Cortex:_27.38
  • Esophagus_-_Mucosa:_17.34
  • Breast_-_Mammary_Tissue:_15.47
  • Skin_-_Sun_Exposed_(Lower_leg):_14.59
  • Pituitary:_13.06
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_9.46
  • Vagina:_9.20
  • Bladder:_6.10
  • Testis:_5.57
  • Fallopian_Tube:_4.72
  • Adipose_-_Visceral_(Omentum):_1.17
  • Liver:_0.97
  • Colon_-_Sigmoid:_0.56
  • Cervix_-_Endocervix:_0.44
  • Cervix_-_Ectocervix:_0.30
  • Ovary:_0.29
  • Brain_-_Cerebellum:_0.29
  • Cells_-_EBV-transformed_lymphocytes:_0.26
  • Uterus:_0.25
  • Cells_-_Transformed_fibroblasts:_0.23
  • Brain_-_Cerebellar_Hemisphere:_0.21
  • Nerve_-_Tibial:_0.20
  • Esophagus_-_Gastroesophageal_Junction:_0.19
  • Esophagus_-_Muscularis:_0.19
  • Artery_-_Aorta:_0.19
  • Artery_-_Coronary:_0.17
  • Spleen:_0.15
  • Artery_-_Tibial:_0.15
  • Adrenal_Gland:_0.13
  • Adipose_-_Subcutaneous:_0.12
  • Heart_-_Atrial_Appendage:_0.12
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.11
  • Brain_-_Cortex:_0.11
  • Brain_-_Frontal_Cortex_(BA9):_0.10
  • Brain_-_Spinal_cord_(cervical_c-1):_0.10
  • Brain_-_Caudate_(basal_ganglia):_0.09
  • Brain_-_Hypothalamus:_0.09
  • Brain_-_Putamen_(basal_ganglia):_0.08
  • Muscle_-_Skeletal:_0.08
  • Brain_-_Substantia_nigra:_0.07
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.07
  • Whole_Blood:_0.07
  • Brain_-_Hippocampus:_0.07
  • Brain_-_Amygdala:_0.06
  • Heart_-_Left_Ventricle:_0.05
  • 37>NX_Q9C073-1|F117A_HUMAN FAM117A GN=FAM117A
    MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPF
    QLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYL
    LGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTD
    HRKEISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSG
    SPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPP
    QSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTP
    NDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVF
    EEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRN
    CPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSS
    LMV


    chromosome location: 49710332-49789180 (17q21.33)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0022891_(0.51)_substrate-specific_transmembrane
    transporter_activity
    GO:0005459_(0.40)_UDP-galactose_transmembrane
    transporter_activity
    GO:0003824_(0.23)_catalytic_activity
    GO:0072341_(0.17)_modified_amino_acid_binding
    GO:0033218_(0.17)_amide_binding
    GO:0019842_(0.17)_vitamin_binding
    GO:0005261_(0.10)_cation_channel_activity
    GO:0022843_(0.09)_voltage-gated_cation_channel
    activity
    GO:0005262_(0.09)_calcium_channel_activity
    GO:0005245_(0.08)_voltage-gated_calcium_channel
    activity
    GO:0016740_(0.06)_transferase_activity
    GO:0008092_(0.06)_cytoskeletal_protein_binding
    GO:0016772_(0.05)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0008331_(0.05)_high_voltage-gated_calcium
    channel_activity
    GO:0008332_(0.04)_low_voltage-gated_calcium
    channel_activity
    BP:
    GO:0044699_(0.84)_single-organism_process
    GO:0009987_(0.62)_cellular_process
    GO:0044763_(0.55)_single-organism_cellular_process
    GO:0032501_(0.48)_multicellular_organismal_process
    GO:0044767_(0.46)_single-organism_developmental
    process
    GO:0048856_(0.44)_anatomical_structure_development
    GO:0048869_(0.42)_cellular_developmental_process
    GO:0003008_(0.40)_system_process
    GO:0051179_(0.37)_localization
    GO:0072015_(0.36)_glomerular_visceral_epithelial
    cell_development
    GO:0006810_(0.36)_transport
    GO:0003094_(0.36)_glomerular_filtration
    GO:0044765_(0.28)_single-organism_transport
    GO:0071702_(0.26)_organic_substance_transport
    GO:0065007_(0.26)_biological_regulation
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.96)_intracellular_part
    GO:0044444_(0.62)_cytoplasmic_part
    GO:0005737_(0.57)_cytoplasm
    GO:0044422_(0.38)_organelle_part
    GO:0044446_(0.36)_intracellular_organelle_part
    GO:0043229_(0.35)_intracellular_organelle
    GO:0032991_(0.29)_macromolecular_complex
    GO:0043234_(0.28)_protein_complex
    GO:0044425_(0.25)_membrane_part
    GO:0043227_(0.25)_membrane-bounded_organelle
    GO:0043231_(0.24)_intracellular_membrane-bounded
    organelle
    GO:0016021_(0.22)_integral_component_of_membrane
    GO:0044431_(0.21)_Golgi_apparatus_part
    GO:0030176_(0.21)_integral_component_of
    endoplasmic_reticulum_membrane

    UniProt annotation score: ◉◉○○○

    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells;
    peripheral_nerve/ganglion)
  • gallbladder_(glandular_cells)
  • kidney_(cells_in_tubules)
  • testis_(Leydig_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • duodenum_(glandular_cells)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells)
  • breast_(glandular_cells;_myoepithelial_cells)
  • rectum_(glandular_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • pancreas_(exocrine_glandular_cells)
  • cerebellum_(Purkinje_cells)
  • fallopian_tube_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(fibroblasts)
  • small_intestine_(glandular_cells)
  • soft_tissue_1_(fibroblasts)
  • lung_(pneumocytes)
  • skin_1_(fibroblasts)
    Medium:
  • lung_(macrophages)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_glomeruli)
  • testis_(cells_in_seminiferous_ducts)
  • caudate_(glial_cells;_neuronal_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • breast_(adipocytes)
  • vagina_(squamous_epithelial_cells)
  • endometrium_1_(cells_in_endometrial_stroma)
  • endometrium_2_(cells_in_endometrial_stroma)
  • smooth_muscle_(smooth_muscle_cells)
  • heart_muscle_(myocytes)
  • cerebral_cortex_(endothelial_cells;_glial
    cells;_neuronal_cells)
  • lymph_node_(non-germinal_center_cells)
  • hippocampus_(glial_cells;_neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • skeletal_muscle_(myocytes)
  • appendix_(lymphoid_tissue)
  • liver_(bile_duct_cells;_hepatocytes)
  • cervix,_uterine_(glandular_cells)
  • pancreas_(islets_of_Langerhans)
  • cerebellum_(cells_in_granular_layer;_cells_in
    molecular_layer)
  • soft_tissue_1_(adipocytes;_chondrocytes;
    peripheral_nerve)
  • soft_tissue_2_(peripheral_nerve)
  • ovary_(follicle_cells;_ovarian_stroma_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(keratinocytes;_Langerhans;
    melanocytes)
  • skin_2_(epidermal_cells)
    Low:
  • lymph_node_(germinal_center_cells)
  • cerebral_cortex_(neuropil)
  • Spleen:_45.19
  • Cells_-_EBV-transformed_lymphocytes:_41.30
  • Uterus:_35.30
  • Whole_Blood:_34.07
  • Testis:_33.86
  • Artery_-_Tibial:_32.15
  • Colon_-_Sigmoid:_30.59
  • Ovary:_30.38
  • Bladder:_29.34
  • Fallopian_Tube:_27.13
  • Skin_-_Sun_Exposed_(Lower_leg):_23.26
  • Artery_-_Coronary:_23.02
  • Esophagus_-_Gastroesophageal_Junction:_22.82
  • Thyroid:_22.63
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_22.63
  • Artery_-_Aorta:_21.55
  • Pituitary:_21.19
  • Esophagus_-_Muscularis:_20.98
  • Small_Intestine_-_Terminal_Ileum:_20.40
  • Cervix_-_Endocervix:_18.95
  • Nerve_-_Tibial:_18.16
  • Adipose_-_Subcutaneous:_16.77
  • Brain_-_Cerebellum:_16.15
  • Breast_-_Mammary_Tissue:_16.10
  • Vagina:_15.19
  • Cervix_-_Ectocervix:_15.01
  • Brain_-_Cerebellar_Hemisphere:_14.06
  • Prostate:_14.03
  • Lung:_13.81
  • Colon_-_Transverse:_12.93
  • Minor_Salivary_Gland:_12.73
  • Adipose_-_Visceral_(Omentum):_12.46
  • Stomach:_10.55
  • Esophagus_-_Mucosa:_9.50
  • Pancreas:_7.96
  • Heart_-_Atrial_Appendage:_7.74
  • Kidney_-_Cortex:_7.69
  • Adrenal_Gland:_7.50
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_6.59
  • Liver:_5.75
  • Heart_-_Left_Ventricle:_5.11
  • Brain_-_Caudate_(basal_ganglia):_4.78
  • Cells_-_Transformed_fibroblasts:_4.31
  • Brain_-_Hypothalamus:_3.70
  • Brain_-_Putamen_(basal_ganglia):_3.61
  • Brain_-_Cortex:_3.48
  • Brain_-_Amygdala:_3.44
  • Brain_-_Frontal_Cortex_(BA9):_3.38
  • Brain_-_Anterior_cingulate_cortex_(BA24):_3.32
  • Brain_-_Hippocampus:_2.92
  • Brain_-_Spinal_cord_(cervical_c-1):_2.36
  • Brain_-_Substantia_nigra:_2.33
  • Muscle_-_Skeletal:_2.04
  • 38>NX_Q8IZD0-1|SAM14_HUMAN Sterile alpha motif domain-containing protein 14 GN=SAMD14
    MASSKLREPVDEVFDLDLAVPETARLDSSLHKARAQLLAKGRRHRPSRSR
    LRDSASSAEDGEGSDGPGGKVTDGCGSPLHRLRSPLHSGPGSPAGGSFCL
    DPPGLRRSLDEDEPPPSPLTRYRPLHNAASHEGLAAASCSPPRSAPSSDS
    SPSFVRRHPRAEPHSEDDSRDASPPEPASPTIGLDKKTRRKFLDLGVTLR
    RASTGKSRKEKGSNRLSMGSRESVEGSGRSGGSPFLPFSWFTDSGKGSAS
    SGSTTSPTCSPKHEGFSPKKSASQESTLSDDSTPPSSSPKIPSGPWQEAK
    CSYPYHTLSQSSDEFLDEPLPPVHHWTSQQVGQWLQSLNLEQYAAEFAAR
    QVDGPQLLQLDGSKLKSLGLSNSHDRALVKRKLKEMAAAAEKERKAQEKA
    ARQREKLRRREQEAKKS


    chromosome location: 50110040-50129882 (17q21.33)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.55)_catalytic_activity
    GO:0044877_(0.48)_macromolecular_complex_binding
    GO:0032403_(0.47)_protein_complex_binding
    GO:0051015_(0.45)_actin_filament_binding
    GO:1901363_(0.43)_heterocyclic_compound_binding
    GO:0097159_(0.43)_organic_cyclic_compound_binding
    GO:0043169_(0.42)_cation_binding
    GO:0097367_(0.41)_carbohydrate_derivative_binding
    GO:0017076_(0.41)_purine_nucleotide_binding
    GO:0035639_(0.40)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.40)_adenyl_ribonucleotide_binding
    GO:0032550_(0.40)_purine_ribonucleoside_binding
    GO:0016879_(0.40)_ligase_activity,_forming_carbon-
    nitrogen_bonds
    GO:0016421_(0.25)_CoA_carboxylase_activity
    GO:0016740_(0.13)_transferase_activity
    BP:
    GO:0044699_(0.84)_single-organism_process
    GO:0009987_(0.83)_cellular_process
    GO:0065007_(0.80)_biological_regulation
    GO:0050789_(0.78)_regulation_of_biological_process
    GO:0044763_(0.75)_single-organism_cellular_process
    GO:0050794_(0.73)_regulation_of_cellular_process
    GO:0016043_(0.64)_cellular_component_organization
    GO:0007165_(0.61)_signal_transduction
    GO:0030030_(0.49)_cell_projection_organization
    GO:0035556_(0.47)_intracellular_signal
    transduction
    GO:0019932_(0.46)_second-messenger-mediated
    signaling
    GO:0031175_(0.45)_neuron_projection_development
    GO:0019722_(0.45)_calcium-mediated_signaling
    GO:0007015_(0.44)_actin_filament_organization
    GO:0071704_(0.37)_organic_substance_metabolic
    process
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0043226_(0.84)_organelle
    GO:0043229_(0.83)_intracellular_organelle
    GO:0044444_(0.81)_cytoplasmic_part
    GO:0005737_(0.81)_cytoplasm
    GO:0044446_(0.64)_intracellular_organelle_part
    GO:0043232_(0.61)_intracellular_non-membrane-
    bounded_organelle
    GO:0043231_(0.61)_intracellular_membrane-bounded
    organelle
    GO:0097458_(0.53)_neuron_part
    GO:0042995_(0.51)_cell_projection
    GO:0044456_(0.50)_synapse_part
    GO:0043005_(0.50)_neuron_projection
    GO:0016020_(0.50)_membrane
    GO:0005856_(0.50)_cytoskeleton
    GO:0015629_(0.42)_actin_cytoskeleton

    UniProt annotation score: ◉◉○○○

  • Brain_-_Cerebellum:_129.40
  • Brain_-_Cerebellar_Hemisphere:_128.30
  • Brain_-_Cortex:_37.99
  • Brain_-_Frontal_Cortex_(BA9):_34.44
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_32.69
  • Brain_-_Anterior_cingulate_cortex_(BA24):_30.72
  • Brain_-_Amygdala:_24.09
  • Brain_-_Caudate_(basal_ganglia):_22.49
  • Brain_-_Putamen_(basal_ganglia):_20.32
  • Brain_-_Hippocampus:_19.82
  • Brain_-_Hypothalamus:_17.52
  • Brain_-_Substantia_nigra:_10.44
  • Lung:_8.99
  • Artery_-_Aorta:_8.57
  • Brain_-_Spinal_cord_(cervical_c-1):_6.31
  • Artery_-_Coronary:_6.27
  • Pituitary:_6.23
  • Prostate:_5.28
  • Testis:_4.72
  • Uterus:_4.63
  • Artery_-_Tibial:_3.76
  • Cervix_-_Ectocervix:_3.42
  • Esophagus_-_Gastroesophageal_Junction:_3.35
  • Kidney_-_Cortex:_2.77
  • Spleen:_2.65
  • Ovary:_2.59
  • Bladder:_2.54
  • Cervix_-_Endocervix:_2.53
  • Vagina:_2.25
  • Esophagus_-_Muscularis:_2.19
  • Cells_-_Transformed_fibroblasts:_2.05
  • Thyroid:_2.00
  • Colon_-_Sigmoid:_1.95
  • Adrenal_Gland:_1.80
  • Adipose_-_Subcutaneous:_1.66
  • Small_Intestine_-_Terminal_Ileum:_1.47
  • Nerve_-_Tibial:_1.46
  • Adipose_-_Visceral_(Omentum):_1.44
  • Fallopian_Tube:_1.42
  • Colon_-_Transverse:_1.26
  • Whole_Blood:_1.22
  • Stomach:_1.21
  • Heart_-_Atrial_Appendage:_1.18
  • Cells_-_EBV-transformed_lymphocytes:_0.95
  • Breast_-_Mammary_Tissue:_0.91
  • Muscle_-_Skeletal:_0.81
  • Skin_-_Sun_Exposed_(Lower_leg):_0.72
  • Esophagus_-_Mucosa:_0.71
  • Heart_-_Left_Ventricle:_0.65
  • Liver:_0.57
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.55
  • Minor_Salivary_Gland:_0.31
  • Pancreas:_0.19
  • 39>NX_Q6AI12-1|ANR40_HUMAN Ankyrin repeat domain-containing protein 40 GN=ANKRD40
    MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHW
    ACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDD
    DDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPST
    PPASPPADGSPPLLPPGEPPLLGTFPRDHTSLALVQNGDVSAPSAILRTP
    ESTKPGPVCQPPVSQSRSLFSSVPSKPPMSLEPQNGTYAGPAPAFQPFFF
    TGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCEL
    GVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAA
    STLTERPCYNRRASKLTY


    chromosome location: 50693190-50707924 (17q21.33)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0019899_(0.64)_enzyme_binding
    GO:0044389_(0.62)_ubiquitin-like_protein_ligase
    binding
    GO:0008092_(0.62)_cytoskeletal_protein_binding
    GO:0030507_(0.57)_spectrin_binding
    GO:0008093_(0.57)_cytoskeletal_adaptor_activity
    GO:0044877_(0.51)_macromolecular_complex_binding
    GO:0008134_(0.51)_transcription_factor_binding
    GO:0005048_(0.50)_signal_sequence_binding
    GO:0005200_(0.49)_structural_constituent_of
    cytoskeleton
    GO:0051117_(0.48)_ATPase_binding
    GO:0003824_(0.33)_catalytic_activity
    GO:0016740_(0.30)_transferase_activity
    GO:0044325_(0.29)_ion_channel_binding
    GO:0019901_(0.29)_protein_kinase_binding
    GO:0004842_(0.26)_ubiquitin-protein_transferase
    activity
    BP:
    GO:0065007_(0.82)_biological_regulation
    GO:0050789_(0.78)_regulation_of_biological_process
    GO:0050794_(0.77)_regulation_of_cellular_process
    GO:0009987_(0.76)_cellular_process
    GO:0044699_(0.72)_single-organism_process
    GO:0044763_(0.66)_single-organism_cellular_process
    GO:0060255_(0.62)_regulation_of_macromolecule
    metabolic_process
    GO:0007165_(0.62)_signal_transduction
    GO:0080090_(0.61)_regulation_of_primary_metabolic
    process
    GO:0031323_(0.61)_regulation_of_cellular_metabolic
    process
    GO:0051179_(0.60)_localization
    GO:0048522_(0.60)_positive_regulation_of_cellular
    process
    GO:0016043_(0.60)_cellular_component_organization
    GO:0065008_(0.58)_regulation_of_biological_quality
    GO:0050896_(0.58)_response_to_stimulus
    CC:
    GO:0044464_(0.99)_cell_part
    GO:0044424_(0.94)_intracellular_part
    GO:0043229_(0.86)_intracellular_organelle
    GO:0043227_(0.80)_membrane-bounded_organelle
    GO:0043231_(0.79)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.77)_cytoplasm
    GO:0044444_(0.66)_cytoplasmic_part
    GO:0005634_(0.65)_nucleus
    GO:0016020_(0.63)_membrane
    GO:0044425_(0.56)_membrane_part
    GO:0005886_(0.55)_plasma_membrane
    GO:0032991_(0.53)_macromolecular_complex
    GO:0044459_(0.51)_plasma_membrane_part
    GO:0044422_(0.51)_organelle_part
    GO:0043234_(0.51)_protein_complex
    UniProt annotation:
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005515_protein_binding
    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells;
    peripheral_nerve/ganglion)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_glomeruli;_cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts)
  • caudate_(glial_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(cells_in_endometrial_stroma;
    glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
  • cerebral_cortex_(endothelial_cells;_glial
    cells;_neuronal_cells)
  • vagina_(squamous_epithelial_cells)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • hippocampus_(glial_cells;_neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • breast_(glandular_cells)
  • rectum_(glandular_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • duodenum_(glandular_cells)
  • cerebellum_(cells_in_granular_layer;_cells_in
    molecular_layer;_Purkinje_cells)
  • spleen_(cells_in_red_pulp;_cells_in_white
    pulp)
  • bone_marrow_(hematopoietic_cells)
  • small_intestine_(glandular_cells)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages;_pneumocytes)
  • ovary_(follicle_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_2_(epidermal_cells)
    Medium:
  • testis_(Leydig_cells)
  • caudate_(neuronal_cells)
  • fallopian_tube_(glandular_cells)
  • soft_tissue_1_(adipocytes;_chondrocytes;
    fibroblasts;_peripheral_nerve)
  • soft_tissue_2_(fibroblasts;_peripheral_nerve)
  • breast_(myoepithelial_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • smooth_muscle_(smooth_muscle_cells)
    Low:
  • soft_tissue_2_(adipocytes)
  • skeletal_muscle_(myocytes)
  • endometrium_2_(cells_in_endometrial_stroma)
  • heart_muscle_(myocytes)
  • ovary_(ovarian_stroma_cells)
  • liver_(bile_duct_cells)
  • Brain_-_Spinal_cord_(cervical_c-1):_197.80
  • Brain_-_Substantia_nigra:_113.60
  • Brain_-_Hippocampus:_73.81
  • Nerve_-_Tibial:_67.70
  • Brain_-_Putamen_(basal_ganglia):_66.50
  • Brain_-_Amygdala:_63.30
  • Muscle_-_Skeletal:_59.04
  • Brain_-_Hypothalamus:_57.57
  • Brain_-_Caudate_(basal_ganglia):_50.84
  • Artery_-_Tibial:_48.09
  • Brain_-_Cerebellar_Hemisphere:_47.72
  • Adipose_-_Subcutaneous:_47.52
  • Colon_-_Sigmoid:_44.85
  • Brain_-_Cerebellum:_44.44
  • Uterus:_44.05
  • Bladder:_43.69
  • Cervix_-_Ectocervix:_42.92
  • Esophagus_-_Muscularis:_42.48
  • Brain_-_Frontal_Cortex_(BA9):_41.18
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_40.39
  • Adipose_-_Visceral_(Omentum):_39.59
  • Esophagus_-_Gastroesophageal_Junction:_38.53
  • Cells_-_Transformed_fibroblasts:_38.36
  • Artery_-_Coronary:_37.69
  • Cervix_-_Endocervix:_37.63
  • Breast_-_Mammary_Tissue:_36.41
  • Artery_-_Aorta:_36.09
  • Fallopian_Tube:_35.75
  • Brain_-_Cortex:_35.33
  • Lung:_33.29
  • Brain_-_Anterior_cingulate_cortex_(BA24):_33.24
  • Ovary:_31.67
  • Thyroid:_29.28
  • Prostate:_25.90
  • Vagina:_25.37
  • Colon_-_Transverse:_22.83
  • Adrenal_Gland:_22.68
  • Spleen:_22.29
  • Skin_-_Sun_Exposed_(Lower_leg):_19.69
  • Minor_Salivary_Gland:_18.99
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_18.60
  • Cells_-_EBV-transformed_lymphocytes:_18.14
  • Small_Intestine_-_Terminal_Ileum:_17.79
  • Testis:_17.55
  • Stomach:_16.54
  • Heart_-_Atrial_Appendage:_16.20
  • Esophagus_-_Mucosa:_15.85
  • Heart_-_Left_Ventricle:_15.73
  • Pituitary:_15.13
  • Kidney_-_Cortex:_13.69
  • Pancreas:_11.10
  • Liver:_8.64
  • Whole_Blood:_2.91
  • 40>NX_Q0P5P2-1|CQ067_HUMAN Uncharacterized protein C17orf67 GN=C17orf67
    MASFKLADSVWEDSLSKRQRNQGRMKTLPVLVLSLTLLTVFSETSPILTE
    KQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNP
    HCKPHCDRNRIHPV


    chromosome location: 56791913-56838773 (17q22)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0043169_(0.58)_cation_binding
    GO:0004112_(0.58)_cyclic-nucleotide
    phosphodiesterase_activity
    GO:0032561_(0.48)_guanyl_ribonucleotide_binding
    GO:0030551_(0.48)_cyclic_nucleotide_binding
    BP:
    GO:0046068_(0.48)_cGMP_metabolic_process
    GO:0009214_(0.48)_cyclic_nucleotide_catabolic
    process
    GO:0009154_(0.48)_purine_ribonucleotide_catabolic
    process
    GO:2000243_(0.37)_positive_regulation_of
    reproductive_process
    GO:1900542_(0.37)_regulation_of_purine_nucleotide
    metabolic_process
    GO:0090075_(0.37)_relaxation_of_muscle
    GO:0071902_(0.37)_positive_regulation_of_protein
    serine/threonine_kinase_activity
    GO:0060281_(0.37)_regulation_of_oocyte_development
    GO:0055117_(0.37)_regulation_of_cardiac_muscle
    contraction
    GO:0050868_(0.37)_negative_regulation_of_T_cell
    activation
    GO:0050672_(0.37)_negative_regulation_of
    lymphocyte_proliferation
    GO:0045988_(0.37)_negative_regulation_of_striated
    muscle_contraction
    GO:0045822_(0.37)_negative_regulation_of_heart
    contraction
    GO:0043902_(0.37)_positive_regulation_of_multi-
    organism_process
    GO:0043410_(0.37)_positive_regulation_of_MAPK
    cascade
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.87)_intracellular_part
    GO:0044444_(0.73)_cytoplasmic_part
    GO:0005829_(0.53)_cytosol
    GO:0043226_(0.47)_organelle
    GO:0005737_(0.47)_cytoplasm
    GO:0043229_(0.33)_intracellular_organelle
    GO:0016020_(0.33)_membrane
    GO:0044446_(0.27)_intracellular_organelle_part
    GO:0043227_(0.27)_membrane-bounded_organelle
    GO:0097458_(0.20)_neuron_part
    GO:0043231_(0.20)_intracellular_membrane-bounded
    organelle
    GO:0005886_(0.20)_plasma_membrane
    GO:0098590_(0.13)_plasma_membrane_region
    GO:0044421_(0.13)_extracellular_region_part
    UniProt annotation:
    GO:0005515_protein_binding
    GO:0005576_extracellular_region

    UniProt annotation score: ◉◉○○○

    NextProt annotation:
    GO:0005515_protein_binding
  • Uterus:_5.22
  • Testis:_5.08
  • Spleen:_4.93
  • Nerve_-_Tibial:_4.40
  • Prostate:_4.36
  • Ovary:_3.82
  • Cervix_-_Ectocervix:_3.81
  • Cervix_-_Endocervix:_3.79
  • Vagina:_3.75
  • Fallopian_Tube:_3.56
  • Thyroid:_3.24
  • Lung:_3.03
  • Cells_-_EBV-transformed_lymphocytes:_2.90
  • Small_Intestine_-_Terminal_Ileum:_2.83
  • Colon_-_Sigmoid:_2.81
  • Pituitary:_2.80
  • Bladder:_2.73
  • Artery_-_Aorta:_2.70
  • Esophagus_-_Muscularis:_2.51
  • Esophagus_-_Gastroesophageal_Junction:_2.46
  • Adipose_-_Visceral_(Omentum):_2.40
  • Artery_-_Coronary:_2.39
  • Brain_-_Hypothalamus:_2.32
  • Breast_-_Mammary_Tissue:_2.26
  • Brain_-_Cerebellar_Hemisphere:_2.15
  • Brain_-_Cerebellum:_2.12
  • Brain_-_Spinal_cord_(cervical_c-1):_2.08
  • Adipose_-_Subcutaneous:_1.90
  • Liver:_1.87
  • Artery_-_Tibial:_1.85
  • Colon_-_Transverse:_1.73
  • Cells_-_Transformed_fibroblasts:_1.71
  • Brain_-_Frontal_Cortex_(BA9):_1.48
  • Pancreas:_1.38
  • Brain_-_Anterior_cingulate_cortex_(BA24):_1.37
  • Minor_Salivary_Gland:_1.37
  • Brain_-_Substantia_nigra:_1.36
  • Stomach:_1.35
  • Brain_-_Cortex:_1.35
  • Esophagus_-_Mucosa:_1.34
  • Brain_-_Hippocampus:_1.31
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_1.23
  • Brain_-_Amygdala:_1.18
  • Skin_-_Sun_Exposed_(Lower_leg):_1.09
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_1.05
  • Brain_-_Caudate_(basal_ganglia):_1.05
  • Kidney_-_Cortex:_0.96
  • Whole_Blood:_0.89
  • Brain_-_Putamen_(basal_ganglia):_0.83
  • Heart_-_Atrial_Appendage:_0.81
  • Adrenal_Gland:_0.49
  • Heart_-_Left_Ventricle:_0.48
  • Muscle_-_Skeletal:_0.33
  • 41>NX_Q9NWM3-1|CUED1_HUMAN CUE domain-containing protein 1 GN=CUEDC1
    MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQA
    MDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYE
    DSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPP
    TPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNA
    GGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQ
    RNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSE
    DALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAA
    STANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ


    chromosome location: 57861243-57955323 (17q22)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0022892_(0.35)_substrate-specific_transporter
    activity
    GO:0019899_(0.32)_enzyme_binding
    GO:0008331_(0.26)_high_voltage-gated_calcium
    channel_activity
    GO:0005102_(0.23)_receptor_binding
    GO:0042393_(0.20)_histone_binding
    GO:0046872_(0.18)_metal_ion_binding
    GO:0035325_(0.17)_Toll-like_receptor_binding
    GO:0019900_(0.17)_kinase_binding
    GO:0030234_(0.15)_enzyme_regulator_activity
    GO:0051879_(0.12)_Hsp90_protein_binding
    GO:0044822_(0.12)_poly(A)_RNA_binding
    GO:0019904_(0.12)_protein_domain_specific_binding
    GO:0008565_(0.12)_protein_transporter_activity
    GO:0008536_(0.12)_Ran_GTPase_binding
    GO:0008270_(0.12)_zinc_ion_binding
    BP:
    GO:0009987_(0.94)_cellular_process
    GO:0065007_(0.58)_biological_regulation
    GO:0044237_(0.58)_cellular_metabolic_process
    GO:0006796_(0.55)_phosphate-containing_compound
    metabolic_process
    GO:0050794_(0.52)_regulation_of_cellular_process
    GO:0016310_(0.52)_phosphorylation
    GO:0044763_(0.40)_single-organism_cellular_process
    GO:0022402_(0.28)_cell_cycle_process
    GO:0080090_(0.27)_regulation_of_primary_metabolic
    process
    GO:0050896_(0.27)_response_to_stimulus
    GO:0031325_(0.27)_positive_regulation_of_cellular
    metabolic_process
    GO:0010604_(0.27)_positive_regulation_of
    macromolecule_metabolic_process
    GO:0007267_(0.24)_cell-cell_signaling
    GO:0045944_(0.23)_positive_regulation_of
    transcription_from_RNA_polymerase_II_promoter
    GO:0033365_(0.23)_protein_localization_to
    organelle
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0043227_(0.90)_membrane-bounded_organelle
    GO:0005634_(0.85)_nucleus
    GO:0044446_(0.81)_intracellular_organelle_part
    GO:0005737_(0.75)_cytoplasm
    GO:0044428_(0.66)_nuclear_part
    GO:0016020_(0.60)_membrane
    GO:0043234_(0.58)_protein_complex
    GO:0070062_(0.56)_extracellular_exosome
    GO:0044444_(0.56)_cytoplasmic_part
    GO:0005643_(0.54)_nuclear_pore
    GO:0005829_(0.36)_cytosol
    GO:0005654_(0.30)_nucleoplasm
    GO:0044459_(0.24)_plasma_membrane_part
    GO:1902494_(0.23)_catalytic_complex

    UniProt annotation score: ◉◉○○○

    High:
  • cerebellum_(Purkinje_cells)
  • stomach_1_(glandular_cells)
    Medium:
  • stomach_2_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells;
    peripheral_nerve/ganglion)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • caudate_(neuronal_cells)
  • tonsil_(germinal_center_cells;_squamous
    epithelial_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • heart_muscle_(myocytes)
  • pancreas_(exocrine_glandular_cells)
  • cerebral_cortex_(endothelial_cells;_neuronal
    cells;_neuropil)
  • vagina_(squamous_epithelial_cells)
  • lymph_node_(non-germinal_center_cells)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • hippocampus_(neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • skeletal_muscle_(myocytes)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • liver_(bile_duct_cells;_hepatocytes)
  • rectum_(glandular_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • duodenum_(glandular_cells)
  • cerebellum_(cells_in_granular_layer;_cells_in
    molecular_layer)
  • fallopian_tube_(glandular_cells)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(fibroblasts;_peripheral_nerve)
  • skin_2_(epidermal_cells)
  • small_intestine_(glandular_cells)
  • soft_tissue_1_(adipocytes;_fibroblasts;
    peripheral_nerve)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages;_pneumocytes)
  • ovary_(follicle_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    melanocytes)
  • breast_(glandular_cells;_myoepithelial_cells)
    Low:
  • lymph_node_(germinal_center_cells)
  • hippocampus_(glial_cells)
  • caudate_(glial_cells)
  • spleen_(cells_in_red_pulp;_cells_in_white
    pulp)
  • skin_1_(Langerhans)
  • soft_tissue_2_(adipocytes)
  • tonsil_(non-germinal_center_cells)
  • endometrium_1_(cells_in_endometrial_stroma)
  • endometrium_2_(cells_in_endometrial_stroma)
  • breast_(adipocytes)
  • soft_tissue_1_(chondrocytes)
  • ovary_(ovarian_stroma_cells)
  • cerebral_cortex_(glial_cells)
  • kidney_(cells_in_glomeruli)
  • Colon_-_Sigmoid:_57.87
  • Esophagus_-_Muscularis:_57.63
  • Esophagus_-_Gastroesophageal_Junction:_55.70
  • Fallopian_Tube:_48.62
  • Cervix_-_Endocervix:_48.50
  • Uterus:_43.13
  • Prostate:_43.07
  • Nerve_-_Tibial:_41.99
  • Artery_-_Tibial:_39.90
  • Cervix_-_Ectocervix:_39.56
  • Bladder:_39.04
  • Pituitary:_38.66
  • Brain_-_Spinal_cord_(cervical_c-1):_38.15
  • Artery_-_Coronary:_38.02
  • Thyroid:_33.91
  • Vagina:_33.61
  • Artery_-_Aorta:_32.90
  • Muscle_-_Skeletal:_32.63
  • Minor_Salivary_Gland:_31.04
  • Lung:_30.79
  • Cells_-_Transformed_fibroblasts:_29.62
  • Adipose_-_Subcutaneous:_28.40
  • Esophagus_-_Mucosa:_28.32
  • Brain_-_Substantia_nigra:_25.25
  • Breast_-_Mammary_Tissue:_24.50
  • Brain_-_Hypothalamus:_23.76
  • Adrenal_Gland:_23.74
  • Colon_-_Transverse:_23.15
  • Kidney_-_Cortex:_22.78
  • Stomach:_21.86
  • Heart_-_Atrial_Appendage:_21.77
  • Adipose_-_Visceral_(Omentum):_20.26
  • Brain_-_Cerebellum:_19.53
  • Heart_-_Left_Ventricle:_18.29
  • Brain_-_Putamen_(basal_ganglia):_18.21
  • Brain_-_Cerebellar_Hemisphere:_17.83
  • Brain_-_Hippocampus:_17.49
  • Spleen:_17.43
  • Brain_-_Caudate_(basal_ganglia):_17.12
  • Brain_-_Amygdala:_16.70
  • Skin_-_Sun_Exposed_(Lower_leg):_15.48
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_15.37
  • Ovary:_13.84
  • Brain_-_Cortex:_13.81
  • Brain_-_Anterior_cingulate_cortex_(BA24):_12.93
  • Brain_-_Frontal_Cortex_(BA9):_12.70
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_12.39
  • Pancreas:_11.31
  • Small_Intestine_-_Terminal_Ileum:_10.85
  • Whole_Blood:_6.69
  • Testis:_5.17
  • Liver:_3.29
  • Cells_-_EBV-transformed_lymphocytes:_0.42
  • 42>NX_Q8NEP4-1|CQ047_HUMAN Uncharacterized protein C17orf47 GN=C17orf47
    MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSH
    RRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGPETGPRTESSRHS
    SPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSI
    PDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGVRVPRRILSYPKDE
    AVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESET
    GPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYS
    AYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHV
    TVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKP
    SIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPK
    CSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSEV
    PQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFSLLWAHCGSLG
    DGRTGEEWHLCIYRAGSFRR


    chromosome location: 58541587-58544368 (17q22)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:1901363_(0.37)_heterocyclic_compound_binding
    GO:0097159_(0.37)_organic_cyclic_compound_binding
    GO:0003676_(0.35)_nucleic_acid_binding
    GO:0003824_(0.21)_catalytic_activity
    GO:0022892_(0.18)_substrate-specific_transporter
    activity
    GO:0015075_(0.17)_ion_transmembrane_transporter
    activity
    GO:0008324_(0.16)_cation_transmembrane_transporter
    activity
    GO:0005216_(0.16)_ion_channel_activity
    GO:0005261_(0.15)_cation_channel_activity
    GO:0046873_(0.13)_metal_ion_transmembrane
    transporter_activity
    GO:0008092_(0.13)_cytoskeletal_protein_binding
    GO:0022843_(0.12)_voltage-gated_cation_channel
    activity
    GO:0016740_(0.12)_transferase_activity
    GO:0015085_(0.12)_calcium_ion_transmembrane
    transporter_activity
    GO:0005262_(0.11)_calcium_channel_activity
    BP:
    GO:0009987_(0.59)_cellular_process
    GO:0044699_(0.51)_single-organism_process
    GO:0065007_(0.50)_biological_regulation
    GO:0044763_(0.42)_single-organism_cellular_process
    GO:0050789_(0.39)_regulation_of_biological_process
    GO:0050794_(0.38)_regulation_of_cellular_process
    GO:0044767_(0.27)_single-organism_developmental
    process
    GO:0016043_(0.26)_cellular_component_organization
    GO:0065008_(0.25)_regulation_of_biological_quality
    GO:0032501_(0.24)_multicellular_organismal_process
    GO:0008152_(0.22)_metabolic_process
    GO:0071704_(0.21)_organic_substance_metabolic
    process
    GO:0051179_(0.21)_localization
    GO:0044238_(0.21)_primary_metabolic_process
    GO:0044237_(0.21)_cellular_metabolic_process
    CC:
    GO:0044464_(0.97)_cell_part
    GO:0044424_(0.95)_intracellular_part
    GO:0032991_(0.69)_macromolecular_complex
    GO:0043234_(0.68)_protein_complex
    GO:0044444_(0.60)_cytoplasmic_part
    GO:0043226_(0.57)_organelle
    GO:0043229_(0.56)_intracellular_organelle
    GO:0044422_(0.47)_organelle_part
    GO:0044446_(0.45)_intracellular_organelle_part
    GO:0005737_(0.41)_cytoplasm
    GO:0043227_(0.40)_membrane-bounded_organelle
    GO:0043231_(0.38)_intracellular_membrane-bounded
    organelle
    GO:1990234_(0.34)_transferase_complex
    GO:0043232_(0.33)_intracellular_non-membrane-
    bounded_organelle
    GO:0016020_(0.33)_membrane

    UniProt annotation score: ◉○○○○

  • Testis:_14.73
  • Spleen:_0.24
  • Lung:_0.22
  • Thyroid:_0.18
  • Pituitary:_0.13
  • Breast_-_Mammary_Tissue:_0.13
  • Minor_Salivary_Gland:_0.11
  • Bladder:_0.11
  • Prostate:_0.11
  • Cervix_-_Ectocervix:_0.11
  • Cervix_-_Endocervix:_0.09
  • Artery_-_Aorta:_0.09
  • Small_Intestine_-_Terminal_Ileum:_0.08
  • Artery_-_Tibial:_0.08
  • Liver:_0.08
  • Stomach:_0.07
  • Artery_-_Coronary:_0.07
  • Nerve_-_Tibial:_0.07
  • Colon_-_Transverse:_0.07
  • Skin_-_Sun_Exposed_(Lower_leg):_0.06
  • Brain_-_Cerebellum:_0.06
  • Pancreas:_0.06
  • Kidney_-_Cortex:_0.05
  • Fallopian_Tube:_0.05
  • Adipose_-_Subcutaneous:_0.05
  • Ovary:_0.05
  • Adipose_-_Visceral_(Omentum):_0.05
  • Adrenal_Gland:_0.05
  • Brain_-_Cerebellar_Hemisphere:_0.04
  • Uterus:_0.04
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.03
  • Cells_-_Transformed_fibroblasts:_0.03
  • Vagina:_0.03
  • Esophagus_-_Mucosa:_0.02
  • Heart_-_Atrial_Appendage:_0.02
  • 43>NX_Q86X59-1|CQ082_HUMAN Putative uncharacterized protein C17orf82 GN=C17orf82
    MGRPLEGQPLRALDLYPEPAFLRSGKDPKSSPASSPSFAVLGPEVRSTGG
    QAGSRRRPSAPCSQDRAAAEGAPALLGGSPSSGSPGHPPGSAFGVEAGCR
    ALNVSEHARGGFALGLPFGLSGGAYLFLLLDGAGDPKPTPEAPISSADGR
    AWFPSESSWQLPQLPAGSTSGSEPRARPGLGPRQLLTGPRDGAAGQGPGR
    GLTARLGREREIDCGPRQAGHGGTATDTGRAGSGARHRPPRDRGTPGLRT
    H


    chromosome location: 61411751-61413280 (17q23.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0015926_(0.39)_glucosidase_activity
    GO:0003676_(0.34)_nucleic_acid_binding
    BP:
    GO:0009987_(0.69)_cellular_process
    GO:0016043_(0.55)_cellular_component_organization
    GO:0032502_(0.52)_developmental_process
    GO:0044699_(0.49)_single-organism_process
    GO:0048856_(0.48)_anatomical_structure_development
    GO:0051179_(0.45)_localization
    GO:0071704_(0.44)_organic_substance_metabolic
    process
    GO:0006810_(0.44)_transport
    GO:0043170_(0.43)_macromolecule_metabolic_process
    GO:0044238_(0.42)_primary_metabolic_process
    GO:0044237_(0.42)_cellular_metabolic_process
    GO:0043933_(0.42)_macromolecular_complex_subunit
    organization
    GO:0022607_(0.42)_cellular_component_assembly
    GO:0044260_(0.40)_cellular_macromolecule_metabolic
    process
    GO:0065003_(0.39)_macromolecular_complex_assembly
    CC:
    GO:0044464_(0.80)_cell_part
    GO:0044424_(0.65)_intracellular_part
    GO:0005576_(0.53)_extracellular_region
    GO:0016020_(0.48)_membrane
    GO:0005737_(0.44)_cytoplasm
    GO:0032991_(0.41)_macromolecular_complex
    GO:0044444_(0.40)_cytoplasmic_part
    GO:0043234_(0.39)_protein_complex
    GO:0044422_(0.38)_organelle_part
    GO:0044446_(0.36)_intracellular_organelle_part
    GO:0005886_(0.33)_plasma_membrane
    GO:0043226_(0.31)_organelle
    GO:0043229_(0.27)_intracellular_organelle
    GO:0043227_(0.27)_membrane-bounded_organelle
    GO:0005829_(0.27)_cytosol
    UniProt annotation:
    GO:0005515_protein_binding

    UniProt annotation score: ◉○○○○

    NextProt annotation:
    GO:0005515_protein_binding
  • Lung:_3.77
  • Prostate:_3.53
  • Artery_-_Coronary:_2.90
  • Artery_-_Aorta:_2.71
  • Cervix_-_Endocervix:_2.65
  • Bladder:_2.29
  • Nerve_-_Tibial:_2.13
  • Artery_-_Tibial:_2.11
  • Uterus:_1.85
  • Cervix_-_Ectocervix:_1.80
  • Fallopian_Tube:_1.68
  • Esophagus_-_Muscularis:_1.46
  • Minor_Salivary_Gland:_1.36
  • Ovary:_1.34
  • Testis:_1.26
  • Esophagus_-_Gastroesophageal_Junction:_1.25
  • Thyroid:_1.20
  • Cells_-_Transformed_fibroblasts:_1.13
  • Breast_-_Mammary_Tissue:_1.08
  • Adipose_-_Subcutaneous:_1.07
  • Vagina:_1.00
  • Spleen:_0.94
  • Kidney_-_Cortex:_0.92
  • Adrenal_Gland:_0.81
  • Adipose_-_Visceral_(Omentum):_0.69
  • Pituitary:_0.51
  • Esophagus_-_Mucosa:_0.40
  • Small_Intestine_-_Terminal_Ileum:_0.39
  • Stomach:_0.34
  • Heart_-_Atrial_Appendage:_0.34
  • Colon_-_Transverse:_0.32
  • Brain_-_Substantia_nigra:_0.32
  • Skin_-_Sun_Exposed_(Lower_leg):_0.29
  • Colon_-_Sigmoid:_0.27
  • Heart_-_Left_Ventricle:_0.24
  • Brain_-_Hypothalamus:_0.22
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.22
  • Brain_-_Spinal_cord_(cervical_c-1):_0.21
  • Brain_-_Caudate_(basal_ganglia):_0.16
  • Muscle_-_Skeletal:_0.16
  • Brain_-_Putamen_(basal_ganglia):_0.15
  • Brain_-_Hippocampus:_0.13
  • Brain_-_Cortex:_0.13
  • Brain_-_Amygdala:_0.12
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.12
  • Liver:_0.11
  • Brain_-_Frontal_Cortex_(BA9):_0.11
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.10
  • Brain_-_Cerebellum:_0.10
  • Pancreas:_0.08
  • Brain_-_Cerebellar_Hemisphere:_0.08
  • Cells_-_EBV-transformed_lymphocytes:_0.05
  • 44>NX_Q8N7B9-1|EFCB3_HUMAN EF-hand calcium-binding domain-containing protein 3 GN=EFCAB3
    MAVSEIKPKLKLNPLTKVPISHNKRDRDLPGSLQCQLQHKEKKLSASQMA
    AFQDAYNFFYKDKTGCIDFHGLMCTVAKLGMNLTKHDVYNELKCADIDRD
    GKVNFSDFIKVLTDKNLFLKAVVPEKETCLDLAGNPGILLFEILSRLLET
    SALPRKSIIEIVSYFQRKFQHTGPGMLWSPYTMGYGKRTLKPDICTPPSS
    SMAAFANAARIAIMKEKDLFKFLEELKRCNSGSDSPYSKIPIFPLFPNVD
    GVVMGKPFKDMQKLEMLRIKEPLHFFEDYFFHKRDWKTQAANIKSMDPAS
    GYSNNIFTIDQMLKKKQTCTVADATAIKQHVKRATDTYNLGIALEHRKEM
    LNLWQKIRGDLIGMDSRNESFYDTFSTYTWSWNVCQELLSPKDLRLYDAY
    VNRNSSHNSRSSSSSDTSECYTDSGRKRKRKGLKGFQQ


    chromosome location: 62343941-62416479 (17q23.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0043169_(0.74)_cation_binding
    GO:0005509_(0.47)_calcium_ion_binding
    GO:0003824_(0.34)_catalytic_activity
    GO:0004672_(0.28)_protein_kinase_activity
    GO:0009931_(0.27)_calcium-dependent_protein
    serine/threonine_kinase_activity
    GO:0005516_(0.27)_calmodulin_binding
    GO:0004683_(0.27)_calmodulin-dependent_protein
    kinase_activity
    GO:0008092_(0.13)_cytoskeletal_protein_binding
    GO:0005198_(0.10)_structural_molecule_activity
    GO:0003735_(0.07)_structural_constituent_of
    ribosome
    GO:0042803_(0.06)_protein_homodimerization
    activity
    GO:0016787_(0.06)_hydrolase_activity
    GO:0051393_(0.05)_alpha-actinin_binding
    GO:0017166_(0.05)_vinculin_binding
    GO:0098772_(0.04)_molecular_function_regulator
    BP:
    GO:0009987_(0.80)_cellular_process
    GO:0065007_(0.64)_biological_regulation
    GO:0071704_(0.61)_organic_substance_metabolic
    process
    GO:0050789_(0.61)_regulation_of_biological_process
    GO:0044238_(0.60)_primary_metabolic_process
    GO:0043170_(0.59)_macromolecule_metabolic_process
    GO:0019538_(0.58)_protein_metabolic_process
    GO:0050794_(0.56)_regulation_of_cellular_process
    GO:0044237_(0.55)_cellular_metabolic_process
    GO:0044260_(0.53)_cellular_macromolecule_metabolic
    process
    GO:0044267_(0.52)_cellular_protein_metabolic
    process
    GO:0007165_(0.46)_signal_transduction
    GO:0050896_(0.43)_response_to_stimulus
    GO:0035556_(0.43)_intracellular_signal
    transduction
    GO:0006796_(0.42)_phosphate-containing_compound
    metabolic_process
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.99)_intracellular_part
    GO:0043226_(0.91)_organelle
    GO:0043229_(0.87)_intracellular_organelle
    GO:0043227_(0.82)_membrane-bounded_organelle
    GO:0016020_(0.82)_membrane
    GO:0044444_(0.80)_cytoplasmic_part
    GO:0043231_(0.80)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.68)_cytoplasm
    GO:0005886_(0.66)_plasma_membrane
    GO:0044422_(0.64)_organelle_part
    GO:0005634_(0.62)_nucleus
    GO:0044446_(0.59)_intracellular_organelle_part
    GO:0044425_(0.56)_membrane_part
    GO:0043234_(0.45)_protein_complex
    UniProt annotation:
    GO:0005509_calcium_ion_binding
    GO:0046872_metal_ion_binding

    UniProt annotation score: ◉◉○○○

    NextProt annotation:
    GO:0005509_calcium_ion_binding
  • Testis:_6.95
  • Brain_-_Frontal_Cortex_(BA9):_0.01
  • 45>NX_Q96GE4-1|CEP95_HUMAN Centrosomal protein of 95 kDa GN=CEP95
    MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPD
    LIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNL
    LEIFDGLLEYLTERISETSHEKSETEQYFKESDRGERLEEPESTKESKSS
    WKRVSFGRCSLSSEMLGPSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQC
    PNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTETLSVSGIPNA
    RKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTE
    FSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASS
    CNSPFPQRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDH
    KEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSL
    SPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQEN
    IGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLP
    KPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKE
    ACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQR
    LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGL
    NIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQE
    HQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELE
    AERFRSRLQLASFQYSKSPSL


    chromosome location: 64506588-64542461 (17q23.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0035639_(0.32)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.32)_adenyl_ribonucleotide_binding
    GO:0032550_(0.32)_purine_ribonucleoside_binding
    GO:0003676_(0.32)_nucleic_acid_binding
    GO:0003824_(0.29)_catalytic_activity
    BP:
    GO:0009987_(0.71)_cellular_process
    GO:0044699_(0.61)_single-organism_process
    GO:0044763_(0.55)_single-organism_cellular_process
    GO:0016043_(0.38)_cellular_component_organization
    GO:0065007_(0.37)_biological_regulation
    GO:0050789_(0.36)_regulation_of_biological_process
    GO:0050794_(0.35)_regulation_of_cellular_process
    GO:0051179_(0.27)_localization
    GO:0007017_(0.26)_microtubule-based_process
    GO:0032502_(0.25)_developmental_process
    GO:0006928_(0.25)_movement_of_cell_or_subcellular
    component
    GO:0044767_(0.24)_single-organism_developmental
    process
    GO:0008152_(0.23)_metabolic_process
    GO:0006996_(0.23)_organelle_organization
    GO:0071704_(0.22)_organic_substance_metabolic
    process
    CC:
    GO:0005813_(1.00)_centrosome
    GO:0000922_(1.00)_spindle_pole
    UniProt annotation:
    GO:0005813_centrosome
    GO:0000922_spindle_pole
    GO:0005515_protein_binding
    GO:0005815_microtubule_organizing_center
    GO:0005737_cytoplasm
    GO:0005856_cytoskeleton

    UniProt annotation score: ◉◉◉◉○

    NextProt annotation:
    GO:0005515_protein_binding
    High:
  • stomach_2_(glandular_cells)
  • small_intestine_(glandular_cells)
  • epididymis_(glandular_cells)
  • appendix_(glandular_cells)
  • colon_(glandular_cells)
  • ovary_(follicle_cells)
  • urinary_bladder_(urothelial_cells)
  • rectum_(glandular_cells)
  • duodenum_(glandular_cells)
    Medium:
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • lung_(macrophages;_pneumocytes)
  • gallbladder_(glandular_cells)
  • kidney_(cells_in_tubules)
  • testis_(Leydig_cells)
  • tonsil_(squamous_epithelial_cells)
  • endometrium_1_(cells_in_endometrial_stroma;
    glandular_cells)
  • vagina_(squamous_epithelial_cells)
  • salivary_gland_(glandular_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • cerebral_cortex_(endothelial_cells)
  • hippocampus_(neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • breast_(myoepithelial_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • pancreas_(islets_of_Langerhans)
  • cerebellum_(Purkinje_cells)
  • fallopian_tube_(glandular_cells)
  • soft_tissue_1_(fibroblasts)
  • soft_tissue_2_(fibroblasts)
  • nasopharynx_(respiratory_epithelial_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • heart_muscle_(myocytes)
    Low:
  • placenta_(decidual_cells;_trophoblastic_cells)
  • testis_(cells_in_seminiferous_ducts)
  • caudate_(neuronal_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    Langerhans;_melanocytes)
  • tonsil_(non-germinal_center_cells)
  • skeletal_muscle_(myocytes)
  • skin_2_(epidermal_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • colon_(endothelial_cells)
  • breast_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • pancreas_(exocrine_glandular_cells)
  • cerebral_cortex_(neuronal_cells;_neuropil)
  • kidney_(cells_in_glomeruli)
  • liver_(bile_duct_cells)
  • Ovary:_58.72
  • Thyroid:_51.52
  • Cervix_-_Endocervix:_50.88
  • Nerve_-_Tibial:_44.45
  • Brain_-_Cerebellar_Hemisphere:_43.59
  • Testis:_43.59
  • Uterus:_39.58
  • Fallopian_Tube:_38.16
  • Brain_-_Cerebellum:_37.24
  • Cervix_-_Ectocervix:_36.86
  • Prostate:_32.93
  • Colon_-_Sigmoid:_29.49
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_29.06
  • Vagina:_28.59
  • Skin_-_Sun_Exposed_(Lower_leg):_28.48
  • Pituitary:_28.43
  • Bladder:_26.95
  • Breast_-_Mammary_Tissue:_26.51
  • Artery_-_Tibial:_26.31
  • Spleen:_26.30
  • Lung:_26.19
  • Adipose_-_Subcutaneous:_25.83
  • Small_Intestine_-_Terminal_Ileum:_24.34
  • Esophagus_-_Gastroesophageal_Junction:_22.89
  • Artery_-_Aorta:_22.09
  • Cells_-_EBV-transformed_lymphocytes:_21.30
  • Artery_-_Coronary:_21.21
  • Colon_-_Transverse:_21.18
  • Esophagus_-_Muscularis:_20.43
  • Adipose_-_Visceral_(Omentum):_19.90
  • Minor_Salivary_Gland:_19.89
  • Cells_-_Transformed_fibroblasts:_18.24
  • Kidney_-_Cortex:_16.55
  • Stomach:_16.48
  • Esophagus_-_Mucosa:_16.12
  • Brain_-_Spinal_cord_(cervical_c-1):_13.34
  • Adrenal_Gland:_12.04
  • Pancreas:_11.33
  • Brain_-_Frontal_Cortex_(BA9):_9.91
  • Brain_-_Cortex:_9.90
  • Heart_-_Atrial_Appendage:_9.89
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_9.88
  • Brain_-_Hypothalamus:_9.67
  • Brain_-_Caudate_(basal_ganglia):_9.45
  • Liver:_9.38
  • Muscle_-_Skeletal:_8.96
  • Brain_-_Substantia_nigra:_8.68
  • Brain_-_Hippocampus:_8.36
  • Brain_-_Putamen_(basal_ganglia):_8.15
  • Brain_-_Amygdala:_7.86
  • Brain_-_Anterior_cingulate_cortex_(BA24):_7.79
  • Heart_-_Left_Ventricle:_5.88
  • Whole_Blood:_4.27
  • 46>NX_O60309-1|L37A3_HUMAN Leucine-rich repeat-containing protein 37A3 GN=LRRC37A3
    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLT
    SNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQ
    ESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKL
    KKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELR
    VKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLL
    EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
    PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP
    MEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHH
    QTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVE
    PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAA
    EHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG
    FTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
    PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ
    VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL
    PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPD
    LGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA
    QDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ
    RLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
    LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVIT
    ELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLV
    PLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSAC
    LTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINL
    SGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNS
    LAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT
    AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKP
    FSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVH
    SRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSL
    INSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEEN
    VFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNV
    GTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT
    LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTEN
    YINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLC
    LIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP


    chromosome location: 64854312-64919480 (17q24.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0098772_(0.29)_molecular_function_regulator
    GO:0004860_(0.28)_protein_kinase_inhibitor
    activity
    GO:0097367_(0.17)_carbohydrate_derivative_binding
    GO:0005102_(0.17)_receptor_binding
    GO:0004872_(0.16)_receptor_activity
    GO:0005539_(0.15)_glycosaminoglycan_binding
    GO:0008201_(0.14)_heparin_binding
    GO:0048495_(0.13)_Roundabout_binding
    GO:0004871_(0.12)_signal_transducer_activity
    GO:0038023_(0.11)_signaling_receptor_activity
    GO:0003824_(0.10)_catalytic_activity
    GO:0003676_(0.10)_nucleic_acid_binding
    GO:0004888_(0.08)_transmembrane_signaling_receptor
    activity
    GO:0003723_(0.07)_RNA_binding
    GO:0004930_(0.06)_G-protein_coupled_receptor
    activity
    BP:
    GO:0065007_(0.62)_biological_regulation
    GO:0050789_(0.60)_regulation_of_biological_process
    GO:0050794_(0.59)_regulation_of_cellular_process
    GO:0009987_(0.59)_cellular_process
    GO:0044699_(0.54)_single-organism_process
    GO:0044763_(0.48)_single-organism_cellular_process
    GO:0007165_(0.47)_signal_transduction
    GO:0032502_(0.45)_developmental_process
    GO:0044767_(0.44)_single-organism_developmental
    process
    GO:0016043_(0.35)_cellular_component_organization
    GO:0048583_(0.34)_regulation_of_response_to
    stimulus
    GO:0007166_(0.32)_cell_surface_receptor_signaling
    pathway
    GO:0009653_(0.31)_anatomical_structure
    morphogenesis
    GO:0019222_(0.30)_regulation_of_metabolic_process
    GO:0048869_(0.29)_cellular_developmental_process
    CC:
    GO:0044464_(0.77)_cell_part
    GO:0044424_(0.57)_intracellular_part
    GO:0005737_(0.38)_cytoplasm
    GO:0044421_(0.26)_extracellular_region_part
    GO:0044425_(0.20)_membrane_part
    GO:0031012_(0.20)_extracellular_matrix
    GO:0043226_(0.19)_organelle
    GO:0005615_(0.19)_extracellular_space
    GO:0005578_(0.18)_proteinaceous_extracellular
    matrix
    GO:0044459_(0.16)_plasma_membrane_part
    GO:0031224_(0.16)_intrinsic_component_of_membrane
    GO:0016020_(0.16)_membrane
    GO:0043229_(0.15)_intracellular_organelle
    GO:0043227_(0.15)_membrane-bounded_organelle
    GO:0044444_(0.14)_cytoplasmic_part
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    High:
  • testis_(elongated_or_late_spermatids;_round_or
    early_spermatids)
    Low:
  • testis_(pachytene_spermatocytes;_preleptotene
    spermatocytes)
  • Testis:_20.21
  • Pituitary:_14.32
  • Thyroid:_12.72
  • Brain_-_Cerebellar_Hemisphere:_8.97
  • Brain_-_Cerebellum:_8.47
  • Brain_-_Hypothalamus:_5.96
  • Prostate:_5.39
  • Ovary:_4.94
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_4.81
  • Nerve_-_Tibial:_4.79
  • Brain_-_Cortex:_4.58
  • Brain_-_Frontal_Cortex_(BA9):_4.53
  • Fallopian_Tube:_3.95
  • Kidney_-_Cortex:_3.85
  • Brain_-_Anterior_cingulate_cortex_(BA24):_3.71
  • Brain_-_Caudate_(basal_ganglia):_3.62
  • Uterus:_3.45
  • Cervix_-_Endocervix:_3.26
  • Brain_-_Hippocampus:_3.06
  • Brain_-_Amygdala:_3.01
  • Artery_-_Coronary:_2.98
  • Vagina:_2.96
  • Brain_-_Substantia_nigra:_2.85
  • Breast_-_Mammary_Tissue:_2.77
  • Brain_-_Putamen_(basal_ganglia):_2.77
  • Artery_-_Aorta:_2.77
  • Lung:_2.71
  • Artery_-_Tibial:_2.68
  • Brain_-_Spinal_cord_(cervical_c-1):_2.59
  • Cervix_-_Ectocervix:_2.50
  • Spleen:_2.39
  • Adipose_-_Subcutaneous:_2.33
  • Bladder:_2.09
  • Esophagus_-_Gastroesophageal_Junction:_2.08
  • Colon_-_Sigmoid:_2.04
  • Skin_-_Sun_Exposed_(Lower_leg):_1.98
  • Adipose_-_Visceral_(Omentum):_1.87
  • Cells_-_Transformed_fibroblasts:_1.75
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_1.72
  • Esophagus_-_Muscularis:_1.72
  • Adrenal_Gland:_1.65
  • Minor_Salivary_Gland:_1.53
  • Small_Intestine_-_Terminal_Ileum:_1.41
  • Esophagus_-_Mucosa:_1.39
  • Colon_-_Transverse:_1.24
  • Stomach:_0.90
  • Heart_-_Atrial_Appendage:_0.90
  • Pancreas:_0.86
  • Liver:_0.83
  • Whole_Blood:_0.60
  • Muscle_-_Skeletal:_0.46
  • Cells_-_EBV-transformed_lymphocytes:_0.46
  • Heart_-_Left_Ventricle:_0.38
  • 47>NX_Q2M2W7-1|CQ058_HUMAN UPF0450 protein C17orf58 GN=C17orf58
    MNRLYLTPDGFFFRVHMLALDSSSCNKPCPEFKPGSRYIVMGHIYHKRRQ
    LPTALLQVLRGRLRPGDGLLRSSSSYVKRFNRKREGQIQGAIHTQCI


    chromosome location: 67991101-67996431 (17q24.2)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0046872_(0.13)_metal_ion_binding
    GO:0008191_(0.13)_metalloendopeptidase_inhibitor
    activity
    GO:0004252_(0.13)_serine-type_endopeptidase
    activity
    GO:0002020_(0.13)_protease_binding
    GO:0048037_(0.07)_cofactor_binding
    GO:0031715_(0.07)_C5L2_anaphylatoxin_chemotactic
    receptor_binding
    GO:0016504_(0.07)_peptidase_activator_activity
    GO:0008289_(0.07)_lipid_binding
    GO:0008201_(0.07)_heparin_binding
    GO:0008083_(0.07)_growth_factor_activity
    GO:0005518_(0.07)_collagen_binding
    GO:0005125_(0.07)_cytokine_activity
    GO:0001849_(0.07)_complement_component_C1q_binding
    BP:
    GO:0052548_(0.37)_regulation_of_endopeptidase
    activity
    GO:0010466_(0.37)_negative_regulation_of_peptidase
    activity
    CC:
    GO:0044464_(0.80)_cell_part
    GO:0043227_(0.80)_membrane-bounded_organelle
    GO:0005615_(0.67)_extracellular_space
    GO:0005576_(0.67)_extracellular_region
    GO:0031988_(0.60)_membrane-bounded_vesicle
    GO:0070062_(0.53)_extracellular_exosome
    GO:0044424_(0.47)_intracellular_part
    GO:0044446_(0.33)_intracellular_organelle_part
    GO:0043231_(0.33)_intracellular_membrane-bounded
    organelle
    GO:0016020_(0.33)_membrane
    GO:0044444_(0.27)_cytoplasmic_part
    GO:0044425_(0.27)_membrane_part
    GO:0032991_(0.27)_macromolecular_complex
    GO:0031012_(0.27)_extracellular_matrix
    GO:0005886_(0.27)_plasma_membrane

    UniProt annotation score: ◉◉○○○

  • Cervix_-_Endocervix:_27.79
  • Cervix_-_Ectocervix:_25.84
  • Brain_-_Cerebellar_Hemisphere:_20.25
  • Uterus:_18.65
  • Vagina:_17.90
  • Breast_-_Mammary_Tissue:_16.43
  • Brain_-_Cerebellum:_15.99
  • Adipose_-_Subcutaneous:_14.13
  • Cells_-_Transformed_fibroblasts:_13.85
  • Brain_-_Frontal_Cortex_(BA9):_12.89
  • Fallopian_Tube:_12.55
  • Adipose_-_Visceral_(Omentum):_12.51
  • Bladder:_12.12
  • Thyroid:_11.74
  • Brain_-_Anterior_cingulate_cortex_(BA24):_10.80
  • Brain_-_Cortex:_10.39
  • Artery_-_Coronary:_10.17
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_9.74
  • Adrenal_Gland:_9.63
  • Prostate:_9.51
  • Brain_-_Amygdala:_9.28
  • Nerve_-_Tibial:_9.05
  • Brain_-_Caudate_(basal_ganglia):_9.01
  • Esophagus_-_Gastroesophageal_Junction:_8.91
  • Esophagus_-_Mucosa:_8.58
  • Pituitary:_8.50
  • Testis:_8.40
  • Esophagus_-_Muscularis:_8.35
  • Brain_-_Hypothalamus:_8.05
  • Ovary:_7.96
  • Artery_-_Aorta:_7.78
  • Small_Intestine_-_Terminal_Ileum:_7.71
  • Minor_Salivary_Gland:_7.45
  • Colon_-_Transverse:_7.35
  • Brain_-_Hippocampus:_7.30
  • Brain_-_Putamen_(basal_ganglia):_7.27
  • Brain_-_Substantia_nigra:_7.26
  • Brain_-_Spinal_cord_(cervical_c-1):_7.18
  • Lung:_7.14
  • Stomach:_6.96
  • Colon_-_Sigmoid:_6.90
  • Heart_-_Atrial_Appendage:_6.82
  • Spleen:_6.64
  • Skin_-_Sun_Exposed_(Lower_leg):_6.44
  • Liver:_6.31
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_6.16
  • Kidney_-_Cortex:_6.05
  • Artery_-_Tibial:_5.06
  • Pancreas:_4.76
  • Cells_-_EBV-transformed_lymphocytes:_4.39
  • Heart_-_Left_Ventricle:_4.00
  • Muscle_-_Skeletal:_2.57
  • Whole_Blood:_0.83
  • 48>NX_Q969W3-1|F104A_HUMAN FAM104A GN=FAM104A
    MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSV
    PSLRGAAPRSFHPPAAMSERLRPRKRRRNGNEEDNHLPPQTKRSSRNPVF
    QDSWDTESSGSDSGGSSSSSSSSINSPDRASGPEGSLSQTMAGSSPNTPQ
    PVPEQSALCQGLYFHINQTLREAHFHSLQHRGRPLT


    chromosome location: 73207353-73236753 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0042802_(0.13)_identical_protein_binding
    GO:0005086_(0.13)_ARF_guanyl-nucleotide_exchange
    factor_activity
    GO:0035091_(0.07)_phosphatidylinositol_binding
    GO:0034987_(0.07)_immunoglobulin_receptor_binding
    GO:0008017_(0.07)_microtubule_binding
    GO:0005524_(0.07)_ATP_binding
    GO:0005096_(0.07)_GTPase_activator_activity
    GO:0004715_(0.07)_non-membrane_spanning_protein
    tyrosine_kinase_activity
    BP:
    GO:0044260_(0.81)_cellular_macromolecule_metabolic
    process
    GO:0044238_(0.81)_primary_metabolic_process
    GO:0006950_(0.81)_response_to_stress
    GO:0042276_(0.80)_error-prone_translesion
    synthesis
    GO:0043547_(0.11)_positive_regulation_of_GTPase
    activity
    GO:0006897_(0.11)_endocytosis
    GO:2000251_(0.06)_positive_regulation_of_actin
    cytoskeleton_reorganization
    GO:2000145_(0.06)_regulation_of_cell_motility
    GO:0090339_(0.06)_negative_regulation_of_formin-
    nucleated_actin_cable_assembly
    GO:0051297_(0.06)_centrosome_organization
    GO:0051056_(0.06)_regulation_of_small_GTPase
    mediated_signal_transduction
    GO:0045639_(0.06)_positive_regulation_of_myeloid
    cell_differentiation
    GO:0045087_(0.06)_innate_immune_response
    GO:0043304_(0.06)_regulation_of_mast_cell
    degranulation
    GO:0042127_(0.06)_regulation_of_cell_proliferation
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0043229_(0.98)_intracellular_organelle
    GO:0043231_(0.96)_intracellular_membrane-bounded
    organelle
    GO:0044446_(0.90)_intracellular_organelle_part
    GO:0032991_(0.86)_macromolecular_complex
    GO:0043234_(0.85)_protein_complex
    GO:0005634_(0.84)_nucleus
    GO:0044444_(0.82)_cytoplasmic_part
    GO:0061695_(0.81)_transferase_complex,
    transferring_phosphorus-containing_groups
    GO:0016035_(0.80)_zeta_DNA_polymerase_complex
    GO:0005829_(0.68)_cytosol
    GO:0044425_(0.63)_membrane_part
    GO:0016020_(0.57)_membrane
    GO:0005737_(0.57)_cytoplasm
    GO:0031982_(0.51)_vesicle
    UniProt annotation:
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉○○○

    NextProt annotation:
    GO:0005515_protein_binding
  • Testis:_140.40
  • Cells_-_EBV-transformed_lymphocytes:_49.85
  • Cells_-_Transformed_fibroblasts:_34.17
  • Skin_-_Sun_Exposed_(Lower_leg):_23.85
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_23.27
  • Cervix_-_Endocervix:_22.90
  • Cervix_-_Ectocervix:_22.40
  • Adipose_-_Subcutaneous:_21.89
  • Bladder:_21.26
  • Artery_-_Tibial:_21.19
  • Artery_-_Aorta:_20.76
  • Vagina:_20.54
  • Breast_-_Mammary_Tissue:_20.18
  • Pituitary:_19.60
  • Fallopian_Tube:_19.44
  • Artery_-_Coronary:_19.41
  • Esophagus_-_Mucosa:_18.98
  • Lung:_18.66
  • Thyroid:_18.64
  • Uterus:_18.59
  • Prostate:_18.59
  • Nerve_-_Tibial:_18.56
  • Brain_-_Cerebellar_Hemisphere:_18.30
  • Spleen:_18.00
  • Adipose_-_Visceral_(Omentum):_17.68
  • Ovary:_17.42
  • Brain_-_Cerebellum:_16.99
  • Whole_Blood:_16.94
  • Esophagus_-_Muscularis:_15.19
  • Esophagus_-_Gastroesophageal_Junction:_14.83
  • Minor_Salivary_Gland:_14.52
  • Colon_-_Sigmoid:_14.18
  • Small_Intestine_-_Terminal_Ileum:_14.09
  • Stomach:_13.49
  • Colon_-_Transverse:_13.07
  • Adrenal_Gland:_12.63
  • Brain_-_Spinal_cord_(cervical_c-1):_11.38
  • Brain_-_Frontal_Cortex_(BA9):_11.16
  • Brain_-_Cortex:_10.62
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_10.42
  • Muscle_-_Skeletal:_10.10
  • Brain_-_Anterior_cingulate_cortex_(BA24):_8.77
  • Brain_-_Hypothalamus:_8.58
  • Brain_-_Caudate_(basal_ganglia):_8.54
  • Pancreas:_7.97
  • Brain_-_Amygdala:_7.91
  • Kidney_-_Cortex:_7.78
  • Heart_-_Atrial_Appendage:_7.66
  • Brain_-_Substantia_nigra:_7.56
  • Brain_-_Hippocampus:_7.38
  • Brain_-_Putamen_(basal_ganglia):_6.85
  • Liver:_6.04
  • Heart_-_Left_Ventricle:_5.60
  • 49>NX_Q9BSJ5-1|CQ080_HUMAN Uncharacterized protein C17orf80 GN=C17orf80
    MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLP
    RAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGL
    ERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKR
    ELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTT
    SGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVRTLLSNER
    DSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGL
    TLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGER
    PHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDV
    KALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAA
    AGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGE
    RLSQVSLLERSSTHIRSLEPPAGLTTSNFSLMRLLGAVQKGWIRCNTTIR
    KSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTG
    DCRSKTCLD


    chromosome location: 73232233-73248947 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:1901363_(0.43)_heterocyclic_compound_binding
    GO:0097159_(0.43)_organic_cyclic_compound_binding
    GO:0097367_(0.40)_carbohydrate_derivative_binding
    GO:0035639_(0.39)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.39)_adenyl_ribonucleotide_binding
    GO:0032550_(0.39)_purine_ribonucleoside_binding
    GO:0008092_(0.35)_cytoskeletal_protein_binding
    GO:0003676_(0.35)_nucleic_acid_binding
    GO:0003824_(0.34)_catalytic_activity
    GO:0043169_(0.30)_cation_binding
    GO:0005198_(0.20)_structural_molecule_activity
    GO:0005201_(0.16)_extracellular_matrix_structural
    constituent
    GO:0030674_(0.14)_protein_binding,_bridging
    GO:0030507_(0.12)_spectrin_binding
    GO:0008093_(0.12)_cytoskeletal_adaptor_activity
    BP:
    GO:0009987_(0.71)_cellular_process
    GO:0044699_(0.64)_single-organism_process
    GO:0065007_(0.63)_biological_regulation
    GO:0044763_(0.62)_single-organism_cellular_process
    GO:0032501_(0.47)_multicellular_organismal_process
    GO:0044767_(0.46)_single-organism_developmental
    process
    GO:0016043_(0.46)_cellular_component_organization
    GO:0065008_(0.44)_regulation_of_biological_quality
    GO:0050794_(0.42)_regulation_of_cellular_process
    GO:0044707_(0.37)_single-multicellular_organism
    process
    GO:0006996_(0.33)_organelle_organization
    GO:0051239_(0.30)_regulation_of_multicellular
    organismal_process
    GO:0023051_(0.29)_regulation_of_signaling
    GO:0010646_(0.29)_regulation_of_cell_communication
    GO:0003008_(0.29)_system_process
    CC:
    GO:0070062_(0.97)_extracellular_exosome
    GO:0005753_(0.03)_mitochondrial_proton-
    transporting_ATP_synthase_complex
    UniProt annotation:
    GO:0070062_extracellular_exosome
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

  • Testis:_36.04
  • Brain_-_Cerebellar_Hemisphere:_19.23
  • Cervix_-_Endocervix:_18.88
  • Uterus:_18.29
  • Brain_-_Cerebellum:_17.64
  • Ovary:_17.46
  • Thyroid:_16.31
  • Fallopian_Tube:_15.56
  • Colon_-_Sigmoid:_15.52
  • Cells_-_Transformed_fibroblasts:_15.40
  • Pituitary:_15.35
  • Cells_-_EBV-transformed_lymphocytes:_14.82
  • Bladder:_13.84
  • Esophagus_-_Gastroesophageal_Junction:_13.82
  • Nerve_-_Tibial:_13.68
  • Esophagus_-_Muscularis:_13.63
  • Artery_-_Tibial:_13.11
  • Prostate:_13.10
  • Cervix_-_Ectocervix:_12.82
  • Artery_-_Coronary:_12.64
  • Artery_-_Aorta:_12.20
  • Muscle_-_Skeletal:_12.04
  • Spleen:_11.78
  • Vagina:_10.04
  • Adrenal_Gland:_9.94
  • Adipose_-_Subcutaneous:_9.80
  • Lung:_9.57
  • Breast_-_Mammary_Tissue:_9.51
  • Small_Intestine_-_Terminal_Ileum:_9.01
  • Minor_Salivary_Gland:_8.99
  • Colon_-_Transverse:_8.73
  • Adipose_-_Visceral_(Omentum):_8.54
  • Brain_-_Spinal_cord_(cervical_c-1):_8.36
  • Stomach:_8.18
  • Brain_-_Frontal_Cortex_(BA9):_8.13
  • Brain_-_Cortex:_7.97
  • Brain_-_Hypothalamus:_7.47
  • Skin_-_Sun_Exposed_(Lower_leg):_7.12
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_7.05
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_7.03
  • Brain_-_Anterior_cingulate_cortex_(BA24):_6.73
  • Brain_-_Caudate_(basal_ganglia):_6.69
  • Esophagus_-_Mucosa:_6.63
  • Brain_-_Substantia_nigra:_6.52
  • Kidney_-_Cortex:_6.47
  • Heart_-_Atrial_Appendage:_6.21
  • Heart_-_Left_Ventricle:_5.86
  • Brain_-_Hippocampus:_5.61
  • Brain_-_Amygdala:_5.53
  • Brain_-_Putamen_(basal_ganglia):_5.35
  • Pancreas:_4.79
  • Liver:_3.98
  • Whole_Blood:_2.07
  • 50>NX_Q7RTS6-1|OTOP2_HUMAN Otopetrin-2 GN=OTOP2
    MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGG
    AFNKVAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGP
    IWLRGGLVLFGICTLIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQ
    TYFLWVSAKDCVHVHLDLTWCGLMFTLTTNLAIWMAAVVDESVHQSHSYS
    SSHSNASHARLISDQHADNPVGGDSCLCSTAVCQIFQQGYFYLYPFNIEY
    SLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGPVLGLLLF
    VVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIY
    RFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLA
    GLNLTHALLMIAQHTFQNMFIIESLHRGPPGAEPHSTHPKEPCQDLTFTN
    LDALHTLSACPPNPGLVSPSPSDQREAVAIVSTPRSQWRRQCLKDISLFL
    LLCNVILWIMPAFGARPHFSNTVEVDFYGYSLWAVIVNICLPFGIFYRMH
    AVSSLLEVYVLS


    chromosome location: 74924275-74933912 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0046983_(0.55)_protein_dimerization_activity
    GO:0046873_(0.55)_metal_ion_transmembrane
    transporter_activity
    GO:0042802_(0.55)_identical_protein_binding
    GO:0031420_(0.55)_alkali_metal_ion_binding
    GO:0015077_(0.55)_monovalent_inorganic_cation
    transmembrane_transporter_activity
    GO:0009678_(0.39)_hydrogen-translocating
    pyrophosphatase_activity
    GO:0004427_(0.39)_inorganic_diphosphatase_activity
    BP:
    GO:0042472_(1.00)_inner_ear_morphogenesis
    GO:0009590_(0.51)_detection_of_gravity
    GO:0045299_(0.49)_otolith_mineralization
    GO:0032475_(0.49)_otolith_formation
    GO:0098662_(0.41)_inorganic_cation_transmembrane
    transport
    GO:0030001_(0.41)_metal_ion_transport
    GO:0015992_(0.28)_proton_transport
    CC:
    GO:0016020_(0.86)_membrane
    GO:0044464_(0.72)_cell_part
    GO:0016021_(0.61)_integral_component_of_membrane
    GO:0032991_(0.35)_macromolecular_complex
    GO:0005886_(0.35)_plasma_membrane
    GO:0044424_(0.31)_intracellular_part
    GO:0043234_(0.31)_protein_complex
    GO:1902494_(0.27)_catalytic_complex
    GO:0005737_(0.24)_cytoplasm
    GO:0044459_(0.20)_plasma_membrane_part
    GO:0009380_(0.20)_excinuclease_repair_complex
    GO:0044444_(0.13)_cytoplasmic_part
    GO:0098797_(0.10)_plasma_membrane_protein_complex
    GO:0070469_(0.10)_respiratory_chain
    GO:0043226_(0.10)_organelle
    UniProt annotation:
    Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. {ECO:0000250|UniProtKB:Q80SX5}.

    GO:1902600_proton_transmembrane_transport
    GO:0015252_proton_channel_activity
    GO:0005886_plasma_membrane
    GO:0016020_membrane
    GO:0006811_ion_transport
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

  • Colon_-_Transverse:_12.45
  • Testis:_10.48
  • Esophagus_-_Mucosa:_1.68
  • Small_Intestine_-_Terminal_Ileum:_1.53
  • Skin_-_Sun_Exposed_(Lower_leg):_0.39
  • Uterus:_0.30
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.13
  • Vagina:_0.11
  • Brain_-_Cerebellum:_0.07
  • Cervix_-_Ectocervix:_0.06
  • Brain_-_Cerebellar_Hemisphere:_0.06
  • Bladder:_0.05
  • Colon_-_Sigmoid:_0.05
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.03
  • Fallopian_Tube:_0.02
  • Nerve_-_Tibial:_0.02
  • Spleen:_0.02
  • Minor_Salivary_Gland:_0.02
  • Adipose_-_Subcutaneous:_0.02
  • Adrenal_Gland:_0.02
  • Brain_-_Caudate_(basal_ganglia):_0.01
  • Whole_Blood:_0.01
  • 51>NX_Q86X02-1|CDR2L_HUMAN Cerebellar degeneration-related protein 2-like GN=CDR2L
    MRRAAGMEDFSAEEEESWYDQQDLEQDLHLAAELGKTLLERNKELEGSLQ
    QMYSTNEEQVQEIEYLTKQLDTLRHVNEQHAKVYEQLDLTARDLELTNHR
    LVLESKAAQQKIHGLTETIERLQAQVEELQAQVEQLRGLEQLRVLREKRE
    RRRTIHTFPCLKELCTSPRCKDAFRLHSSSLELGPRPLEQENERLQTLVG
    ALRSQVSQERQRKERAEREYTAVLQEYSELERQLCEMEACRLRVQELEAE
    LLELQQMKQAKTYLLGPDDHLAEALLAPLTQAPEADDPQPGRGDDLGAQD
    GVSSPAASPGHVVRKSCSDTALNAIVAKDPASRHAGNLTLHANSVRKRGM
    SILREVDEQYHALLEKYEELLSKCRQHGAGVRHAGVQTSRPISRDSSWRD
    LRGGEEGQGEVKAGEKSLSQHVEAVDKRLEQSQPEYKALFKEIFSRIQKT
    KADINATKVKTHSSK


    chromosome location: 74987632-75005800 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003824_(0.49)_catalytic_activity
    GO:0016787_(0.46)_hydrolase_activity
    GO:0017111_(0.45)_nucleoside-triphosphatase
    activity
    GO:0008092_(0.37)_cytoskeletal_protein_binding
    GO:1901363_(0.35)_heterocyclic_compound_binding
    GO:0097159_(0.35)_organic_cyclic_compound_binding
    GO:0035639_(0.33)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.33)_adenyl_ribonucleotide_binding
    GO:0032550_(0.33)_purine_ribonucleoside_binding
    GO:0016887_(0.19)_ATPase_activity
    GO:0003774_(0.19)_motor_activity
    GO:0003777_(0.16)_microtubule_motor_activity
    GO:0019899_(0.07)_enzyme_binding
    GO:0016740_(0.05)_transferase_activity
    GO:0008574_(0.05)_ATP-dependent_microtubule_motor
    activity,_plus-end-directed
    BP:
    GO:0009987_(0.90)_cellular_process
    GO:0044699_(0.83)_single-organism_process
    GO:0044763_(0.80)_single-organism_cellular_process
    GO:0016043_(0.52)_cellular_component_organization
    GO:0006996_(0.44)_organelle_organization
    GO:0022607_(0.37)_cellular_component_assembly
    GO:0007010_(0.36)_cytoskeleton_organization
    GO:0070925_(0.33)_organelle_assembly
    GO:0043933_(0.31)_macromolecular_complex_subunit
    organization
    GO:0043623_(0.30)_cellular_protein_complex
    assembly
    GO:0065007_(0.29)_biological_regulation
    GO:0031106_(0.28)_septin_ring_organization
    GO:0050789_(0.27)_regulation_of_biological_process
    GO:0007017_(0.27)_microtubule-based_process
    GO:0051179_(0.26)_localization
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.99)_intracellular_part
    GO:0044446_(0.89)_intracellular_organelle_part
    GO:0044430_(0.87)_cytoskeletal_part
    GO:0043226_(0.87)_organelle
    GO:0043229_(0.86)_intracellular_organelle
    GO:0044444_(0.85)_cytoplasmic_part
    GO:0005737_(0.80)_cytoplasm
    GO:0032991_(0.65)_macromolecular_complex
    GO:0043234_(0.64)_protein_complex
    GO:0043232_(0.61)_intracellular_non-membrane-
    bounded_organelle
    GO:0016459_(0.54)_myosin_complex
    GO:0016020_(0.49)_membrane
    GO:0043227_(0.41)_membrane-bounded_organelle
    GO:0043231_(0.40)_intracellular_membrane-bounded
    organelle
    UniProt annotation:
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉◉○○

    NextProt annotation:
    GO:0005515_protein_binding
    High:
  • cerebellum_(cells_in_granular_layer;_Purkinje
    cells)
  • placenta_(decidual_cells)
  • small_intestine_(glandular_cells)
  • tonsil_(germinal_center_cells;_squamous
    epithelial_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • gallbladder_(glandular_cells)
  • stomach_2_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • rectum_(glandular_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • duodenum_(glandular_cells)
    Medium:
  • stomach_1_(glandular_cells)
  • colon_(glandular_cells;_peripheral
    nerve/ganglion)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts)
  • caudate_(neuronal_cells)
  • tonsil_(non-germinal_center_cells)
  • thyroid_gland_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • vagina_(squamous_epithelial_cells)
  • cerebral_cortex_(neuropil)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • placenta_(trophoblastic_cells)
  • hippocampus_(neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • breast_(glandular_cells;_myoepithelial_cells)
  • prostate_(glandular_cells)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
  • cerebellum_(cells_in_molecular_layer)
  • fallopian_tube_(glandular_cells)
  • spleen_(cells_in_red_pulp)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(fibroblasts)
  • soft_tissue_1_(fibroblasts)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(fibroblasts;_keratinocytes;
    melanocytes)
  • skin_2_(epidermal_cells)
    Low:
  • testis_(Leydig_cells)
  • caudate_(glial_cells)
  • spleen_(cells_in_white_pulp)
  • skin_1_(Langerhans)
  • skeletal_muscle_(myocytes)
  • endometrium_1_(cells_in_endometrial_stroma)
  • salivary_gland_(glandular_cells)
  • colon_(endothelial_cells)
  • heart_muscle_(myocytes)
  • smooth_muscle_(smooth_muscle_cells)
  • soft_tissue_1_(adipocytes)
  • seminal_vesicle_(glandular_cells)
  • lung_(pneumocytes)
  • ovary_(ovarian_stroma_cells)
  • cerebral_cortex_(endothelial_cells)
  • kidney_(cells_in_glomeruli)
  • liver_(hepatocytes)
  • Brain_-_Cerebellum:_128.70
  • Brain_-_Cerebellar_Hemisphere:_119.50
  • Brain_-_Spinal_cord_(cervical_c-1):_55.35
  • Cells_-_Transformed_fibroblasts:_30.72
  • Lung:_27.12
  • Artery_-_Aorta:_26.23
  • Cervix_-_Ectocervix:_24.84
  • Uterus:_24.66
  • Artery_-_Tibial:_23.05
  • Cervix_-_Endocervix:_22.42
  • Artery_-_Coronary:_22.34
  • Stomach:_21.27
  • Esophagus_-_Gastroesophageal_Junction:_20.80
  • Brain_-_Substantia_nigra:_20.39
  • Colon_-_Sigmoid:_19.69
  • Testis:_19.44
  • Esophagus_-_Muscularis:_18.70
  • Bladder:_16.37
  • Fallopian_Tube:_16.36
  • Adipose_-_Visceral_(Omentum):_16.01
  • Breast_-_Mammary_Tissue:_15.65
  • Brain_-_Hippocampus:_15.36
  • Prostate:_15.24
  • Vagina:_14.93
  • Nerve_-_Tibial:_14.40
  • Small_Intestine_-_Terminal_Ileum:_14.21
  • Brain_-_Hypothalamus:_13.67
  • Minor_Salivary_Gland:_13.59
  • Adipose_-_Subcutaneous:_13.57
  • Brain_-_Putamen_(basal_ganglia):_12.48
  • Brain_-_Frontal_Cortex_(BA9):_12.43
  • Brain_-_Cortex:_12.40
  • Kidney_-_Cortex:_12.40
  • Pituitary:_11.90
  • Heart_-_Atrial_Appendage:_11.76
  • Heart_-_Left_Ventricle:_11.31
  • Thyroid:_10.75
  • Brain_-_Caudate_(basal_ganglia):_9.86
  • Esophagus_-_Mucosa:_9.73
  • Colon_-_Transverse:_8.81
  • Brain_-_Amygdala:_8.51
  • Skin_-_Sun_Exposed_(Lower_leg):_8.37
  • Adrenal_Gland:_8.00
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_7.06
  • Brain_-_Anterior_cingulate_cortex_(BA24):_7.05
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_6.85
  • Ovary:_6.15
  • Spleen:_3.16
  • Pancreas:_2.93
  • Muscle_-_Skeletal:_1.54
  • Liver:_1.01
  • Whole_Blood:_0.19
  • Cells_-_EBV-transformed_lymphocytes:_0.12
  • 52>NX_Q12767-1|TMM94_HUMAN Transmembrane protein 94 GN=TMEM94
    MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEV
    WRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNAS
    ALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSA
    MYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASL
    RGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPV
    IDNIRWCLDMALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRF
    IFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMS
    KASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHS
    SSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLT
    DGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPY
    SHHKAHGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCD
    YHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTE
    RLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQE
    NHLALYRLPSAETMKETSLGRLSCVTKRRPPLSHMISLFIKDTTTSTEQM
    LSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFA
    YKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSSWS
    SDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIR
    FVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHA
    GSLHDDLNQVSRDDAEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAK
    LPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCL
    GSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSISMAQASDGLS
    PLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQ
    LTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMS
    MATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRD
    RNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISIT
    HVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHF
    GLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKL
    GMNSPF


    chromosome location: 75441159-75500090 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • Human Protein Atlas
  • MF:
    GO:0043492_(0.91)_ATPase_activity,_coupled_to
    movement_of_substances
    GO:0022892_(0.91)_substrate-specific_transporter
    activity
    GO:0019829_(0.74)_cation-transporting_ATPase
    activity
    GO:0022890_(0.61)_inorganic_cation_transmembrane
    transporter_activity
    GO:0015662_(0.61)_ATPase_activity,_coupled_to
    transmembrane_movement_of_ions,_phosphorylative
    mechanism
    GO:0046873_(0.57)_metal_ion_transmembrane
    transporter_activity
    GO:0015077_(0.41)_monovalent_inorganic_cation
    transmembrane_transporter_activity
    GO:0005524_(0.37)_ATP_binding
    GO:0005391_(0.37)_sodium:potassium-exchanging
    ATPase_activity
    GO:0046872_(0.29)_metal_ion_binding
    GO:0031420_(0.28)_alkali_metal_ion_binding
    GO:0019899_(0.28)_enzyme_binding
    GO:0072509_(0.24)_divalent_inorganic_cation
    transmembrane_transporter_activity
    GO:0004012_(0.24)_phospholipid-translocating
    ATPase_activity
    GO:0005388_(0.23)_calcium-transporting_ATPase
    activity
    BP:
    GO:0009987_(0.90)_cellular_process
    GO:0044699_(0.85)_single-organism_process
    GO:0044763_(0.84)_single-organism_cellular_process
    GO:0065007_(0.81)_biological_regulation
    GO:0065008_(0.80)_regulation_of_biological_quality
    GO:0098771_(0.77)_inorganic_ion_homeostasis
    GO:0030003_(0.77)_cellular_cation_homeostasis
    GO:0006875_(0.72)_cellular_metal_ion_homeostasis
    GO:0006810_(0.71)_transport
    GO:0006812_(0.68)_cation_transport
    GO:0034220_(0.66)_ion_transmembrane_transport
    GO:0098662_(0.65)_inorganic_cation_transmembrane
    transport
    GO:1902600_(0.64)_hydrogen_ion_transmembrane
    transport
    GO:0090662_(0.60)_ATP_hydrolysis_coupled
    transmembrane_transport
    GO:0015988_(0.60)_energy_coupled_proton
    transmembrane_transport,_against_electrochemical
    gradient
    CC:
    GO:0005654_(1.00)_nucleoplasm
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

    High:
  • cerebellum_(cells_in_molecular_layer)
  • hippocampus_(glial_cells)
  • liver_(hepatocytes)
  • bronchus_(respiratory_epithelial_cells)
  • urinary_bladder_(urothelial_cells)
  • small_intestine_(glandular_cells)
  • colon_(glandular_cells)
  • gallbladder_(glandular_cells)
  • lung_(macrophages)
  • cerebral_cortex_(glial_cells;_neuropil)
  • kidney_(cells_in_tubules)
  • duodenum_(glandular_cells)
    Medium:
  • cerebellum_(cells_in_granular_layer)
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • caudate_(glial_cells)
  • seminal_vesicle_(glandular_cells)
  • parathyroid_gland_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • appendix_(glandular_cells)
  • heart_muscle_(myocytes)
  • nasopharynx_(respiratory_epithelial_cells)
  • rectum_(glandular_cells)
    Low:
  • placenta_(trophoblastic_cells)
  • testis_(Leydig_cells)
  • caudate_(neuronal_cells)
  • soft_tissue_2_(fibroblasts)
  • tonsil_(non-germinal_center_cells;_squamous
    epithelial_cells)
  • liver_(bile_duct_cells)
  • skeletal_muscle_(myocytes)
  • epididymis_(glandular_cells)
  • colon_(peripheral_nerve/ganglion)
  • cervix,_uterine_(glandular_cells)
  • pancreas_(exocrine_glandular_cells)
  • kidney_(cells_in_glomeruli)
  • breast_(glandular_cells)
  • 53>NX_Q8WXE0-1|CSKI2_HUMAN Caskin-2 GN=CASKIN2
    MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGF
    SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL
    LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKT
    PLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNG
    HREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIR
    NTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
    LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVG
    IPAARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGD
    RNSVGSEGSVGSIRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLP
    GLHPPSLADNLSHRPLANCRSGEQIFTQDVRPEQLLEGKDAQAIHNWLSE
    FQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRKKIASEIAQLS
    IAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE
    IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEG
    LENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQES
    IGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQG
    PPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHS
    LSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA
    RGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGAT
    GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGL
    PFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE
    PLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP
    TPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGT
    APKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQ
    TSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM
    LD


    chromosome location: 75500261-75515583 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003824_(0.44)_catalytic_activity
    GO:0016740_(0.39)_transferase_activity
    GO:0019899_(0.31)_enzyme_binding
    GO:0004842_(0.25)_ubiquitin-protein_transferase
    activity
    GO:0008092_(0.21)_cytoskeletal_protein_binding
    GO:1901363_(0.18)_heterocyclic_compound_binding
    GO:0097159_(0.18)_organic_cyclic_compound_binding
    GO:0031625_(0.18)_ubiquitin_protein_ligase_binding
    GO:0030507_(0.15)_spectrin_binding
    GO:0008093_(0.15)_cytoskeletal_adaptor_activity
    GO:0016773_(0.14)_phosphotransferase_activity,
    alcohol_group_as_acceptor
    GO:0016301_(0.14)_kinase_activity
    GO:0005215_(0.14)_transporter_activity
    GO:0003676_(0.14)_nucleic_acid_binding
    GO:0008324_(0.13)_cation_transmembrane_transporter
    activity
    BP:
    GO:0065007_(0.71)_biological_regulation
    GO:0050789_(0.66)_regulation_of_biological_process
    GO:0050794_(0.65)_regulation_of_cellular_process
    GO:0009987_(0.42)_cellular_process
    GO:0007165_(0.41)_signal_transduction
    GO:0044699_(0.36)_single-organism_process
    GO:0044763_(0.27)_single-organism_cellular_process
    GO:0016043_(0.24)_cellular_component_organization
    GO:0080090_(0.18)_regulation_of_primary_metabolic
    process
    GO:0060255_(0.18)_regulation_of_macromolecule
    metabolic_process
    GO:0051179_(0.18)_localization
    GO:0044767_(0.18)_single-organism_developmental
    process
    GO:0044237_(0.17)_cellular_metabolic_process
    GO:0031323_(0.17)_regulation_of_cellular_metabolic
    process
    GO:0071704_(0.16)_organic_substance_metabolic
    process
    CC:
    GO:0044464_(0.92)_cell_part
    GO:0044424_(0.84)_intracellular_part
    GO:0005737_(0.60)_cytoplasm
    GO:0043226_(0.46)_organelle
    GO:0043229_(0.45)_intracellular_organelle
    GO:0043231_(0.41)_intracellular_membrane-bounded
    organelle
    GO:0005634_(0.36)_nucleus
    GO:0032991_(0.26)_macromolecular_complex
    GO:0043234_(0.24)_protein_complex
    GO:1902494_(0.19)_catalytic_complex
    GO:0044444_(0.19)_cytoplasmic_part
    GO:0016020_(0.18)_membrane
    GO:0000151_(0.18)_ubiquitin_ligase_complex
    GO:0044422_(0.16)_organelle_part
    GO:0044446_(0.12)_intracellular_organelle_part
    UniProt annotation:
    GO:0016020_membrane
    GO:0005737_cytoplasm

    UniProt annotation score: ◉◉◉○○

    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • cerebral_cortex_(endothelial_cells)
  • kidney_(cells_in_glomeruli)
    Medium:
  • colon_(endothelial_cells;_glandular_cells;
    peripheral_nerve/ganglion)
  • gallbladder_(glandular_cells)
  • kidney_(cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • caudate_(glial_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • duodenum_(glandular_cells)
  • cerebral_cortex_(neuronal_cells)
  • placenta_(trophoblastic_cells)
  • hippocampus_(neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • appendix_(glandular_cells)
  • heart_muscle_(myocytes)
  • rectum_(glandular_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • pancreas_(exocrine_glandular_cells)
  • cerebellum_(cells_in_granular_layer;_cells_in
    molecular_layer;_Purkinje_cells)
  • fallopian_tube_(glandular_cells)
  • soft_tissue_1_(fibroblasts)
  • soft_tissue_2_(fibroblasts)
  • small_intestine_(glandular_cells)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(pneumocytes)
  • ovary_(follicle_cells)
    Low:
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • prostate_(glandular_cells)
  • caudate_(neuronal_cells)
  • spleen_(cells_in_white_pulp)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(peripheral_nerve)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • vagina_(squamous_epithelial_cells)
  • appendix_(lymphoid_tissue)
  • skin_1_(keratinocytes)
  • soft_tissue_1_(peripheral_nerve)
  • esophagus_(squamous_epithelial_cells)
  • skin_2_(epidermal_cells)
  • cerebral_cortex_(neuropil)
  • ovary_(ovarian_stroma_cells)
  • cervix,_uterine_(glandular_cells)
  • pancreas_(islets_of_Langerhans)
  • Nerve_-_Tibial:_140.95
  • Lung:_78.05
  • Fallopian_Tube:_61.11
  • Spleen:_55.80
  • Adipose_-_Visceral_(Omentum):_50.51
  • Thyroid:_50.23
  • Breast_-_Mammary_Tissue:_49.02
  • Uterus:_48.01
  • Adipose_-_Subcutaneous:_46.88
  • Artery_-_Coronary:_37.66
  • Cervix_-_Ectocervix:_36.87
  • Esophagus_-_Muscularis:_36.52
  • Cervix_-_Endocervix:_36.51
  • Esophagus_-_Gastroesophageal_Junction:_35.62
  • Artery_-_Aorta:_33.79
  • Artery_-_Tibial:_32.97
  • Bladder:_32.05
  • Colon_-_Sigmoid:_30.59
  • Prostate:_30.14
  • Kidney_-_Cortex:_28.82
  • Adrenal_Gland:_27.68
  • Vagina:_26.42
  • Pituitary:_26.06
  • Brain_-_Cerebellum:_25.31
  • Ovary:_24.10
  • Brain_-_Spinal_cord_(cervical_c-1):_22.36
  • Skin_-_Sun_Exposed_(Lower_leg):_21.50
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_19.77
  • Brain_-_Cerebellar_Hemisphere:_19.59
  • Stomach:_19.05
  • Brain_-_Cortex:_18.64
  • Colon_-_Transverse:_18.52
  • Minor_Salivary_Gland:_18.49
  • Brain_-_Caudate_(basal_ganglia):_17.23
  • Heart_-_Atrial_Appendage:_16.70
  • Brain_-_Amygdala:_16.41
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_16.08
  • Brain_-_Substantia_nigra:_15.97
  • Brain_-_Putamen_(basal_ganglia):_15.55
  • Heart_-_Left_Ventricle:_15.23
  • Small_Intestine_-_Terminal_Ileum:_15.22
  • Esophagus_-_Mucosa:_15.10
  • Brain_-_Hypothalamus:_14.57
  • Testis:_13.60
  • Brain_-_Frontal_Cortex_(BA9):_13.49
  • Brain_-_Anterior_cingulate_cortex_(BA24):_13.34
  • Brain_-_Hippocampus:_13.29
  • Muscle_-_Skeletal:_11.33
  • Cells_-_Transformed_fibroblasts:_7.78
  • Liver:_7.74
  • Pancreas:_7.32
  • Cells_-_EBV-transformed_lymphocytes:_0.38
  • Whole_Blood:_0.24
  • 54>NX_Q71RC9-1|SMIM5_HUMAN Small integral membrane protein 5 GN=SMIM5
    MAATDFVQEMRAVGERLLLKLQRLPQAEPVEIVAFSVIILFTATVLLLLL
    IACSCCCTHCCCPERRGRKVQVQPTPP


    chromosome location: 75633434-75641404 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0051015_(0.33)_actin_filament_binding
    GO:0030274_(0.33)_LIM_domain_binding
    GO:0017166_(0.33)_vinculin_binding
    GO:0005200_(0.33)_structural_constituent_of
    cytoskeleton
    GO:0005178_(0.33)_integrin_binding
    BP:
    GO:0098876_(0.48)_vesicle-mediated_transport_to
    the_plasma_membrane
    GO:0071702_(0.48)_organic_substance_transport
    GO:0051278_(0.48)_fungal-type_cell_wall
    polysaccharide_biosynthetic_process
    GO:0045184_(0.48)_establishment_of_protein
    localization
    GO:0030010_(0.48)_establishment_of_cell_polarity
    GO:0006892_(0.48)_post-Golgi_vesicle-mediated
    transport
    GO:0006038_(0.48)_cell_wall_chitin_biosynthetic
    process
    GO:0000281_(0.48)_mitotic_cytokinesis
    GO:0070527_(0.33)_platelet_aggregation
    GO:0030866_(0.33)_cortical_actin_cytoskeleton
    organization
    GO:0007044_(0.33)_cell-substrate_junction_assembly
    GO:0007016_(0.33)_cytoskeletal_anchoring_at_plasma
    membrane
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0044446_(0.93)_intracellular_organelle_part
    GO:0043229_(0.93)_intracellular_organelle
    GO:0043227_(0.93)_membrane-bounded_organelle
    GO:0016020_(0.93)_membrane
    GO:0044444_(0.60)_cytoplasmic_part
    GO:0043234_(0.60)_protein_complex
    GO:0044431_(0.53)_Golgi_apparatus_part
    GO:0044425_(0.53)_membrane_part
    GO:0005794_(0.53)_Golgi_apparatus
    GO:0031988_(0.47)_membrane-bounded_vesicle
    GO:0005737_(0.47)_cytoplasm
    GO:0070062_(0.40)_extracellular_exosome
    GO:0044430_(0.40)_cytoskeletal_part
    GO:0034044_(0.40)_exomer_complex
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_glomeruli;_cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts;_Leydig
    cells)
  • caudate_(glial_cells;_neuronal_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(cells_in_endometrial_stroma;
    glandular_cells)
  • endometrium_2_(cells_in_endometrial_stroma;
    glandular_cells)
  • salivary_gland_(glandular_cells)
  • smooth_muscle_(smooth_muscle_cells)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
  • cerebral_cortex_(endothelial_cells;_glial
    cells;_neuronal_cells)
  • vagina_(squamous_epithelial_cells)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • placenta_(decidual_cells;_trophoblastic_cells)
  • hippocampus_(glial_cells;_neuronal_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • skeletal_muscle_(myocytes)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • breast_(glandular_cells;_myoepithelial_cells)
  • rectum_(glandular_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • duodenum_(glandular_cells)
  • cerebellum_(cells_in_granular_layer;_cells_in
    molecular_layer;_Purkinje_cells)
  • fallopian_tube_(glandular_cells)
  • spleen_(cells_in_red_pulp;_cells_in_white
    pulp)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(adipocytes;_peripheral_nerve)
  • skin_2_(epidermal_cells)
  • small_intestine_(glandular_cells)
  • soft_tissue_1_(adipocytes;_chondrocytes)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages;_pneumocytes)
  • ovary_(ovarian_stroma_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(keratinocytes;_melanocytes)
  • heart_muscle_(myocytes)
    Medium:
  • soft_tissue_1_(fibroblasts)
  • soft_tissue_2_(fibroblasts)
  • skin_1_(fibroblasts)
  • breast_(adipocytes)
  • liver_(bile_duct_cells;_hepatocytes)
  • Nerve_-_Tibial:_22.75
  • Thyroid:_19.07
  • Esophagus_-_Mucosa:_17.48
  • Kidney_-_Cortex:_13.62
  • Vagina:_11.37
  • Brain_-_Spinal_cord_(cervical_c-1):_10.94
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_10.23
  • Bladder:_9.60
  • Small_Intestine_-_Terminal_Ileum:_9.44
  • Skin_-_Sun_Exposed_(Lower_leg):_9.41
  • Colon_-_Transverse:_6.65
  • Cervix_-_Endocervix:_5.65
  • Stomach:_5.16
  • Fallopian_Tube:_4.81
  • Colon_-_Sigmoid:_4.11
  • Spleen:_4.00
  • Prostate:_3.37
  • Heart_-_Atrial_Appendage:_3.31
  • Heart_-_Left_Ventricle:_3.20
  • Cervix_-_Ectocervix:_3.15
  • Testis:_3.14
  • Minor_Salivary_Gland:_3.06
  • Esophagus_-_Gastroesophageal_Junction:_2.90
  • Whole_Blood:_2.84
  • Lung:_2.80
  • Brain_-_Substantia_nigra:_2.79
  • Esophagus_-_Muscularis:_2.67
  • Brain_-_Hippocampus:_2.29
  • Ovary:_2.23
  • Pituitary:_2.05
  • Brain_-_Hypothalamus:_1.85
  • Uterus:_1.72
  • Brain_-_Cerebellum:_1.22
  • Artery_-_Coronary:_1.16
  • Breast_-_Mammary_Tissue:_1.13
  • Brain_-_Cerebellar_Hemisphere:_1.05
  • Brain_-_Amygdala:_1.02
  • Brain_-_Caudate_(basal_ganglia):_1.00
  • Brain_-_Putamen_(basal_ganglia):_0.93
  • Adipose_-_Subcutaneous:_0.92
  • Adipose_-_Visceral_(Omentum):_0.91
  • Pancreas:_0.88
  • Brain_-_Cortex:_0.81
  • Brain_-_Frontal_Cortex_(BA9):_0.66
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_0.62
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.52
  • Artery_-_Tibial:_0.52
  • Artery_-_Aorta:_0.48
  • Adrenal_Gland:_0.40
  • Liver:_0.40
  • Cells_-_EBV-transformed_lymphocytes:_0.38
  • Cells_-_Transformed_fibroblasts:_0.19
  • Muscle_-_Skeletal:_0.18
  • 55>NX_Q96LD4-1|TRI47_HUMAN Tripartite motif-containing protein 47 GN=TRIM47
    MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGG
    AARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPS
    APSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLAS
    FCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCL
    CEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSR
    RTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRS
    QGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPG
    PGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSE
    ADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVK
    RVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAE
    DFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGV
    CLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSH
    FAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR


    chromosome location: 75874161-75878575 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.79)_catalytic_activity
    GO:0004842_(0.76)_ubiquitin-protein_transferase
    activity
    GO:0061630_(0.31)_ubiquitin_protein_ligase
    activity
    GO:0046872_(0.21)_metal_ion_binding
    GO:0004871_(0.21)_signal_transducer_activity
    GO:0004872_(0.20)_receptor_activity
    GO:0008329_(0.19)_signaling_pattern_recognition
    receptor_activity
    GO:0008270_(0.19)_zinc_ion_binding
    GO:0042802_(0.16)_identical_protein_binding
    GO:0019899_(0.14)_enzyme_binding
    GO:0016787_(0.14)_hydrolase_activity
    GO:0042803_(0.12)_protein_homodimerization
    activity
    GO:0005102_(0.12)_receptor_binding
    GO:0050827_(0.11)_toxin_receptor_binding
    GO:0004222_(0.11)_metalloendopeptidase_activity
    BP:
    GO:0009987_(0.85)_cellular_process
    GO:0065007_(0.84)_biological_regulation
    GO:0050789_(0.69)_regulation_of_biological_process
    GO:0050794_(0.66)_regulation_of_cellular_process
    GO:0071704_(0.60)_organic_substance_metabolic
    process
    GO:0044238_(0.60)_primary_metabolic_process
    GO:0044260_(0.59)_cellular_macromolecule_metabolic
    process
    GO:0031323_(0.54)_regulation_of_cellular_metabolic
    process
    GO:0019538_(0.54)_protein_metabolic_process
    GO:0060255_(0.53)_regulation_of_macromolecule
    metabolic_process
    GO:0080090_(0.52)_regulation_of_primary_metabolic
    process
    GO:0048518_(0.50)_positive_regulation_of
    biological_process
    GO:0006464_(0.50)_cellular_protein_modification
    process
    GO:0032446_(0.48)_protein_modification_by_small
    protein_conjugation
    GO:0048522_(0.47)_positive_regulation_of_cellular
    process
    CC:
    GO:0044464_(0.99)_cell_part
    GO:0044424_(0.97)_intracellular_part
    GO:0043226_(0.63)_organelle
    GO:0043229_(0.59)_intracellular_organelle
    GO:0005737_(0.57)_cytoplasm
    GO:0043227_(0.52)_membrane-bounded_organelle
    GO:0044444_(0.51)_cytoplasmic_part
    GO:0044422_(0.51)_organelle_part
    GO:0044446_(0.50)_intracellular_organelle_part
    GO:0032991_(0.49)_macromolecular_complex
    GO:0043231_(0.46)_intracellular_membrane-bounded
    organelle
    GO:0016020_(0.41)_membrane
    GO:0005634_(0.41)_nucleus
    GO:0005576_(0.41)_extracellular_region
    GO:0043232_(0.38)_intracellular_non-membrane-
    bounded_organelle
    UniProt annotation:
    GO:0005829_cytosol
    GO:0008270_zinc_ion_binding
    GO:0005622_intracellular
    GO:0046872_metal_ion_binding
    GO:0005737_cytoplasm
    GO:0005634_nucleus

    UniProt annotation score: ◉◉◉◉○

    NextProt annotation:
    GO:0008270_zinc_ion_binding
  • Colon_-_Sigmoid:_107.70
  • Esophagus_-_Muscularis:_103.45
  • Uterus:_93.57
  • Artery_-_Coronary:_88.97
  • Artery_-_Aorta:_88.82
  • Nerve_-_Tibial:_85.15
  • Artery_-_Tibial:_85.11
  • Spleen:_83.52
  • Esophagus_-_Gastroesophageal_Junction:_79.69
  • Vagina:_74.13
  • Bladder:_73.08
  • Cervix_-_Ectocervix:_70.08
  • Cervix_-_Endocervix:_69.11
  • Fallopian_Tube:_67.36
  • Adipose_-_Subcutaneous:_66.47
  • Skin_-_Sun_Exposed_(Lower_leg):_65.64
  • Kidney_-_Cortex:_62.55
  • Breast_-_Mammary_Tissue:_59.55
  • Lung:_58.64
  • Minor_Salivary_Gland:_57.92
  • Adipose_-_Visceral_(Omentum):_56.13
  • Colon_-_Transverse:_54.40
  • Prostate:_54.37
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_51.90
  • Thyroid:_46.51
  • Small_Intestine_-_Terminal_Ileum:_44.42
  • Brain_-_Cerebellum:_43.46
  • Esophagus_-_Mucosa:_42.84
  • Brain_-_Cerebellar_Hemisphere:_34.85
  • Stomach:_32.65
  • Brain_-_Substantia_nigra:_31.42
  • Brain_-_Cortex:_30.84
  • Brain_-_Hypothalamus:_26.32
  • Brain_-_Caudate_(basal_ganglia):_26.04
  • Brain_-_Spinal_cord_(cervical_c-1):_25.95
  • Pituitary:_25.65
  • Brain_-_Putamen_(basal_ganglia):_25.08
  • Brain_-_Frontal_Cortex_(BA9):_24.45
  • Brain_-_Amygdala:_24.20
  • Brain_-_Anterior_cingulate_cortex_(BA24):_24.18
  • Testis:_23.26
  • Brain_-_Hippocampus:_22.74
  • Adrenal_Gland:_21.84
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_21.40
  • Ovary:_20.87
  • Heart_-_Atrial_Appendage:_20.63
  • Liver:_17.68
  • Heart_-_Left_Ventricle:_16.83
  • Cells_-_Transformed_fibroblasts:_14.93
  • Pancreas:_12.18
  • Muscle_-_Skeletal:_7.60
  • Cells_-_EBV-transformed_lymphocytes:_2.86
  • Whole_Blood:_1.38
  • 56>NX_Q8IYN6-1|UBAD2_HUMAN UBA-like domain-containing protein 2 GN=UBALD2
    MSVNMDELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQET
    NIPNSHHHHQMMCTPSNTPATPPNFPDALAMFSKLRASEGLQSSNSPMTA
    AACSPPANFSPFWASSPPSHQAPWIPPSSPTTFHHLHRPQPTWPPGAQQG
    GAQQKAMAAMDGQR


    chromosome location: 76265202-76271299 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.65)_catalytic_activity
    GO:1901363_(0.46)_heterocyclic_compound_binding
    GO:0097159_(0.46)_organic_cyclic_compound_binding
    GO:0043169_(0.41)_cation_binding
    GO:0016491_(0.40)_oxidoreductase_activity
    GO:0046906_(0.39)_tetrapyrrole_binding
    GO:0016684_(0.39)_oxidoreductase_activity,_acting
    on_peroxide_as_acceptor
    GO:0016209_(0.39)_antioxidant_activity
    GO:0016772_(0.28)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0016779_(0.26)_nucleotidyltransferase_activity
    GO:0001055_(0.25)_RNA_polymerase_II_activity
    GO:0016787_(0.12)_hydrolase_activity
    GO:0003676_(0.11)_nucleic_acid_binding
    GO:0001104_(0.11)_RNA_polymerase_II_transcription
    cofactor_activity
    GO:0003723_(0.09)_RNA_binding
    BP:
    GO:0009987_(0.81)_cellular_process
    GO:0044699_(0.73)_single-organism_process
    GO:0008152_(0.64)_metabolic_process
    GO:0044237_(0.62)_cellular_metabolic_process
    GO:0044248_(0.53)_cellular_catabolic_process
    GO:0044763_(0.49)_single-organism_cellular_process
    GO:0050896_(0.44)_response_to_stimulus
    GO:0065007_(0.43)_biological_regulation
    GO:0044710_(0.41)_single-organism_metabolic
    process
    GO:0006950_(0.41)_response_to_stress
    GO:1990748_(0.39)_cellular_detoxification
    GO:0050794_(0.39)_regulation_of_cellular_process
    GO:0044238_(0.39)_primary_metabolic_process
    GO:0043170_(0.39)_macromolecule_metabolic_process
    GO:0042743_(0.39)_hydrogen_peroxide_metabolic
    process
    CC:
    GO:0044464_(0.99)_cell_part
    GO:0044424_(0.96)_intracellular_part
    GO:0043226_(0.73)_organelle
    GO:0043227_(0.71)_membrane-bounded_organelle
    GO:0043229_(0.70)_intracellular_organelle
    GO:0043231_(0.67)_intracellular_membrane-bounded
    organelle
    GO:0044444_(0.64)_cytoplasmic_part
    GO:0044422_(0.62)_organelle_part
    GO:0044446_(0.61)_intracellular_organelle_part
    GO:0005576_(0.55)_extracellular_region
    GO:0032991_(0.46)_macromolecular_complex
    GO:0043234_(0.44)_protein_complex
    GO:0005634_(0.43)_nucleus
    GO:0044428_(0.42)_nuclear_part
    GO:0044451_(0.36)_nucleoplasm_part

    UniProt annotation score: ◉◉○○○

  • Whole_Blood:_205.60
  • Cells_-_EBV-transformed_lymphocytes:_187.70
  • Spleen:_82.09
  • Lung:_78.72
  • Esophagus_-_Mucosa:_72.39
  • Muscle_-_Skeletal:_65.42
  • Small_Intestine_-_Terminal_Ileum:_64.23
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_63.97
  • Skin_-_Sun_Exposed_(Lower_leg):_61.47
  • Nerve_-_Tibial:_58.06
  • Minor_Salivary_Gland:_52.82
  • Breast_-_Mammary_Tissue:_48.19
  • Vagina:_47.25
  • Adipose_-_Subcutaneous:_46.07
  • Cells_-_Transformed_fibroblasts:_44.98
  • Colon_-_Transverse:_44.66
  • Fallopian_Tube:_43.82
  • Thyroid:_43.62
  • Prostate:_41.97
  • Bladder:_41.37
  • Adipose_-_Visceral_(Omentum):_40.88
  • Stomach:_40.66
  • Artery_-_Aorta:_37.25
  • Artery_-_Coronary:_36.20
  • Brain_-_Spinal_cord_(cervical_c-1):_33.42
  • Colon_-_Sigmoid:_29.45
  • Artery_-_Tibial:_28.94
  • Esophagus_-_Muscularis:_28.60
  • Esophagus_-_Gastroesophageal_Junction:_28.32
  • Cervix_-_Endocervix:_27.01
  • Uterus:_26.81
  • Cervix_-_Ectocervix:_26.11
  • Kidney_-_Cortex:_26.11
  • Testis:_25.34
  • Pituitary:_23.77
  • Brain_-_Cerebellum:_22.74
  • Brain_-_Substantia_nigra:_22.02
  • Brain_-_Hypothalamus:_21.59
  • Brain_-_Cerebellar_Hemisphere:_21.06
  • Brain_-_Frontal_Cortex_(BA9):_20.79
  • Ovary:_20.72
  • Brain_-_Cortex:_20.50
  • Brain_-_Hippocampus:_18.25
  • Heart_-_Atrial_Appendage:_18.13
  • Pancreas:_17.61
  • Brain_-_Anterior_cingulate_cortex_(BA24):_17.59
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_17.21
  • Brain_-_Amygdala:_16.99
  • Brain_-_Caudate_(basal_ganglia):_16.68
  • Adrenal_Gland:_15.81
  • Brain_-_Putamen_(basal_ganglia):_15.63
  • Heart_-_Left_Ventricle:_15.00
  • Liver:_12.54
  • 57>NX_Q9H0J4-1|QRIC2_HUMAN Glutamine-rich protein 2 GN=QRICH2
    MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTM
    VTWEELEQAITDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQ
    PSIEQALDSASGLGPDRTASGSGGTAHPSDGVSSREQSKVPSGTGRQQQP
    RARDEAGVPRLHQSSTFQFKSDSDRHRSREKLTSTQPRRNARPGPVQQDL
    PLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLS
    MGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLV
    SVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLT
    LPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTE
    QHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGAD
    QRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVD
    QPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGAD
    QSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGA
    DQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGA
    VQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGV
    DQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGI
    GQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGM
    DQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGR
    EQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLST
    GLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGP
    GYLSADQHGQEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLS
    EGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKD
    LDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAK
    VERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQ
    DRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAH
    TLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKA
    KLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQ
    GLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQE
    LVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQL
    RERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGL
    PGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHS
    KMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYS
    TVPRRCGGSHTLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDG
    HIYKGRMDTRLPGILRKDSSGTSKRKSQQPRPHVHRPPSLSSNGQLPSRP
    QSAQISAGNTSER


    chromosome location: 76274049-76307998 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0003824_(0.38)_catalytic_activity
    GO:0016787_(0.29)_hydrolase_activity
    GO:0017111_(0.26)_nucleoside-triphosphatase
    activity
    GO:0016887_(0.25)_ATPase_activity
    GO:0003774_(0.23)_motor_activity
    GO:0003777_(0.21)_microtubule_motor_activity
    GO:0008092_(0.15)_cytoskeletal_protein_binding
    GO:1901363_(0.12)_heterocyclic_compound_binding
    GO:0097159_(0.12)_organic_cyclic_compound_binding
    GO:0019899_(0.11)_enzyme_binding
    GO:0016740_(0.11)_transferase_activity
    GO:0003676_(0.11)_nucleic_acid_binding
    GO:0015631_(0.08)_tubulin_binding
    GO:0005198_(0.08)_structural_molecule_activity
    GO:0016301_(0.07)_kinase_activity
    BP:
    GO:0009987_(0.79)_cellular_process
    GO:0044699_(0.64)_single-organism_process
    GO:0044763_(0.57)_single-organism_cellular_process
    GO:0016043_(0.43)_cellular_component_organization
    GO:0065007_(0.36)_biological_regulation
    GO:0050789_(0.33)_regulation_of_biological_process
    GO:0050794_(0.31)_regulation_of_cellular_process
    GO:0006996_(0.31)_organelle_organization
    GO:0007017_(0.30)_microtubule-based_process
    GO:0051179_(0.29)_localization
    GO:0006928_(0.29)_movement_of_cell_or_subcellular
    component
    GO:0032502_(0.28)_developmental_process
    GO:0044767_(0.27)_single-organism_developmental
    process
    GO:0051234_(0.26)_establishment_of_localization
    GO:0051641_(0.22)_cellular_localization
    CC:
    GO:0044464_(0.92)_cell_part
    GO:0044424_(0.87)_intracellular_part
    GO:0044422_(0.61)_organelle_part
    GO:0044446_(0.59)_intracellular_organelle_part
    GO:0043226_(0.45)_organelle
    GO:0043229_(0.42)_intracellular_organelle
    GO:0044430_(0.40)_cytoskeletal_part
    GO:0032991_(0.39)_macromolecular_complex
    GO:0044444_(0.36)_cytoplasmic_part
    GO:0043234_(0.36)_protein_complex
    GO:0043227_(0.26)_membrane-bounded_organelle
    GO:0043232_(0.24)_intracellular_non-membrane-
    bounded_organelle
    GO:0043231_(0.23)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.20)_cytoplasm
    GO:0044428_(0.17)_nuclear_part

    UniProt annotation score: ◉◉◉○○

    High:
  • testis_(cells_in_seminiferous_ducts)
  • Testis:_51.16
  • Brain_-_Cerebellum:_13.10
  • Brain_-_Cerebellar_Hemisphere:_12.40
  • Thyroid:_12.03
  • Nerve_-_Tibial:_5.78
  • Minor_Salivary_Gland:_5.09
  • Cervix_-_Endocervix:_4.52
  • Prostate:_4.47
  • Brain_-_Cortex:_4.36
  • Vagina:_4.11
  • Brain_-_Frontal_Cortex_(BA9):_4.02
  • Cervix_-_Ectocervix:_3.98
  • Uterus:_3.77
  • Brain_-_Hypothalamus:_3.75
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_3.67
  • Pituitary:_3.63
  • Fallopian_Tube:_3.61
  • Lung:_3.56
  • Artery_-_Aorta:_3.55
  • Brain_-_Caudate_(basal_ganglia):_3.39
  • Esophagus_-_Mucosa:_3.38
  • Brain_-_Spinal_cord_(cervical_c-1):_3.37
  • Colon_-_Sigmoid:_3.07
  • Artery_-_Coronary:_3.02
  • Ovary:_2.95
  • Brain_-_Putamen_(basal_ganglia):_2.84
  • Brain_-_Anterior_cingulate_cortex_(BA24):_2.79
  • Breast_-_Mammary_Tissue:_2.44
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_2.44
  • Brain_-_Substantia_nigra:_2.34
  • Skin_-_Sun_Exposed_(Lower_leg):_2.24
  • Brain_-_Hippocampus:_2.20
  • Esophagus_-_Gastroesophageal_Junction:_2.17
  • Spleen:_2.13
  • Esophagus_-_Muscularis:_2.13
  • Brain_-_Amygdala:_2.06
  • Colon_-_Transverse:_2.03
  • Bladder:_1.97
  • Small_Intestine_-_Terminal_Ileum:_1.96
  • Artery_-_Tibial:_1.95
  • Cells_-_Transformed_fibroblasts:_1.90
  • Adipose_-_Visceral_(Omentum):_1.70
  • Adipose_-_Subcutaneous:_1.62
  • Liver:_1.61
  • Stomach:_1.51
  • Kidney_-_Cortex:_1.42
  • Pancreas:_1.21
  • Heart_-_Atrial_Appendage:_1.15
  • Adrenal_Gland:_1.04
  • Muscle_-_Skeletal:_0.94
  • Heart_-_Left_Ventricle:_0.84
  • Whole_Blood:_0.58
  • Cells_-_EBV-transformed_lymphocytes:_0.53
  • 58>NX_P84157-1|MXRA7_HUMAN Matrix-remodeling-associated protein 7 GN=MXRA7
    MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEA
    TGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAA
    APAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRG
    NQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKETFGEMSDGDVQEQLR
    LYDM


    chromosome location: 76672551-76711016 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003676_(0.40)_nucleic_acid_binding
    GO:0005198_(0.29)_structural_molecule_activity
    GO:0003824_(0.21)_catalytic_activity
    GO:0003700_(0.12)_transcription_factor_activity,
    sequence-specific_DNA_binding
    GO:0003677_(0.12)_DNA_binding
    GO:0097157_(0.10)_pre-mRNA_intronic_binding
    GO:0030623_(0.10)_U5_snRNA_binding
    GO:0030620_(0.10)_U2_snRNA_binding
    GO:0030619_(0.10)_U1_snRNA_binding
    GO:0017070_(0.10)_U6_snRNA_binding
    GO:0000386_(0.10)_second_spliceosomal
    transesterification_activity
    GO:0005543_(0.09)_phospholipid_binding
    GO:0008324_(0.08)_cation_transmembrane_transporter
    activity
    GO:0004702_(0.07)_receptor_signaling_protein
    serine/threonine_kinase_activity
    GO:0016787_(0.06)_hydrolase_activity
    BP:
    GO:0009987_(0.84)_cellular_process
    GO:0050896_(0.43)_response_to_stimulus
    GO:0051716_(0.37)_cellular_response_to_stimulus
    GO:0006950_(0.31)_response_to_stress
    GO:0044699_(0.30)_single-organism_process
    GO:0044238_(0.30)_primary_metabolic_process
    GO:0043170_(0.30)_macromolecule_metabolic_process
    GO:0016043_(0.29)_cellular_component_organization
    GO:0090304_(0.28)_nucleic_acid_metabolic_process
    GO:0044260_(0.28)_cellular_macromolecule_metabolic
    process
    GO:0044763_(0.27)_single-organism_cellular_process
    GO:0016070_(0.25)_RNA_metabolic_process
    GO:0006979_(0.24)_response_to_oxidative_stress
    GO:0065007_(0.23)_biological_regulation
    GO:0071470_(0.22)_cellular_response_to_osmotic
    stress
    CC:
    GO:0044464_(0.99)_cell_part
    GO:0044424_(0.85)_intracellular_part
    GO:0043227_(0.71)_membrane-bounded_organelle
    GO:0043229_(0.68)_intracellular_organelle
    GO:0043231_(0.67)_intracellular_membrane-bounded
    organelle
    GO:0005634_(0.59)_nucleus
    GO:0044446_(0.55)_intracellular_organelle_part
    GO:0044428_(0.53)_nuclear_part
    GO:0032991_(0.45)_macromolecular_complex
    GO:0009986_(0.30)_cell_surface
    GO:0044444_(0.26)_cytoplasmic_part
    GO:0016020_(0.24)_membrane
    GO:0071013_(0.23)_catalytic_step_2_spliceosome
    GO:0043234_(0.23)_protein_complex
    GO:0005737_(0.23)_cytoplasm
    UniProt annotation:
    GO:0031012_extracellular_matrix
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

  • Artery_-_Aorta:_150.00
  • Artery_-_Tibial:_143.10
  • Artery_-_Coronary:_121.90
  • Colon_-_Sigmoid:_114.40
  • Esophagus_-_Gastroesophageal_Junction:_112.00
  • Esophagus_-_Muscularis:_106.80
  • Uterus:_99.08
  • Fallopian_Tube:_81.21
  • Thyroid:_79.62
  • Cells_-_Transformed_fibroblasts:_78.86
  • Bladder:_75.66
  • Nerve_-_Tibial:_73.11
  • Heart_-_Atrial_Appendage:_71.21
  • Cervix_-_Endocervix:_67.54
  • Adipose_-_Subcutaneous:_65.00
  • Adrenal_Gland:_61.58
  • Ovary:_60.34
  • Cervix_-_Ectocervix:_56.46
  • Adipose_-_Visceral_(Omentum):_49.83
  • Lung:_48.97
  • Prostate:_47.98
  • Breast_-_Mammary_Tissue:_45.38
  • Vagina:_42.71
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_41.77
  • Brain_-_Caudate_(basal_ganglia):_40.85
  • Testis:_40.68
  • Heart_-_Left_Ventricle:_35.09
  • Brain_-_Cerebellar_Hemisphere:_34.34
  • Colon_-_Transverse:_33.58
  • Brain_-_Putamen_(basal_ganglia):_33.32
  • Spleen:_33.21
  • Brain_-_Cerebellum:_31.47
  • Brain_-_Frontal_Cortex_(BA9):_28.18
  • Brain_-_Cortex:_26.57
  • Brain_-_Spinal_cord_(cervical_c-1):_26.43
  • Brain_-_Anterior_cingulate_cortex_(BA24):_22.67
  • Skin_-_Sun_Exposed_(Lower_leg):_22.63
  • Brain_-_Hypothalamus:_22.33
  • Brain_-_Substantia_nigra:_20.81
  • Minor_Salivary_Gland:_18.30
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_17.53
  • Brain_-_Hippocampus:_17.48
  • Brain_-_Amygdala:_16.18
  • Stomach:_15.66
  • Pituitary:_15.53
  • Esophagus_-_Mucosa:_15.24
  • Small_Intestine_-_Terminal_Ileum:_14.31
  • Kidney_-_Cortex:_12.26
  • Muscle_-_Skeletal:_9.52
  • Pancreas:_8.53
  • Whole_Blood:_3.13
  • Liver:_2.96
  • Cells_-_EBV-transformed_lymphocytes:_0.35
  • 59>NX_O43934-1|MFS11_HUMAN UNC93-like protein MFSD11 GN=MFSD11
    MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNRTDFHGSGYT
    SMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWS
    FYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFG
    NLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLG
    EDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTG
    LELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLS
    KNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSS
    KEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAA
    VAFFYSNYLLLHWQLLVMVIFGFFGTISFFTVEWEAAAFVARGSDYRSI


    chromosome location: 76735865-76781449 (17q25.1)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0005215_(0.85)_transporter_activity
    GO:0022857_(0.84)_transmembrane_transporter
    activity
    GO:0022892_(0.78)_substrate-specific_transporter
    activity
    GO:0022891_(0.77)_substrate-specific_transmembrane
    transporter_activity
    GO:0051119_(0.74)_sugar_transmembrane_transporter
    activity
    GO:0015145_(0.72)_monosaccharide_transmembrane
    transporter_activity
    GO:0015149_(0.71)_hexose_transmembrane_transporter
    activity
    GO:0005355_(0.70)_glucose_transmembrane
    transporter_activity
    GO:0008324_(0.67)_cation_transmembrane_transporter
    activity
    GO:0005351_(0.66)_sugar:proton_symporter_activity
    GO:0051183_(0.34)_vitamin_transporter_activity
    GO:0048029_(0.33)_monosaccharide_binding
    GO:0015146_(0.33)_pentose_transmembrane
    transporter_activity
    GO:0015148_(0.32)_D-xylose_transmembrane
    transporter_activity
    GO:0009679_(0.27)_hexose:proton_symporter_activity
    BP:
    GO:0006810_(0.82)_transport
    GO:0044699_(0.74)_single-organism_process
    GO:0071702_(0.70)_organic_substance_transport
    GO:0055085_(0.69)_transmembrane_transport
    GO:0008643_(0.68)_carbohydrate_transport
    GO:0015749_(0.67)_monosaccharide_transport
    GO:0008645_(0.66)_hexose_transport
    GO:0015758_(0.64)_glucose_transport
    GO:0034219_(0.61)_carbohydrate_transmembrane
    transport
    GO:0035428_(0.60)_hexose_transmembrane_transport
    GO:0046323_(0.47)_glucose_import
    GO:0065007_(0.38)_biological_regulation
    GO:0050896_(0.38)_response_to_stimulus
    GO:0006820_(0.38)_anion_transport
    GO:0051716_(0.35)_cellular_response_to_stimulus
    CC:
    GO:0016021_(1.00)_integral_component_of_membrane
    GO:0016020_(1.00)_membrane
    GO:0044464_(0.95)_cell_part
    GO:0005887_(0.77)_integral_component_of_plasma
    membrane
    GO:0005886_(0.70)_plasma_membrane
    GO:0044424_(0.20)_intracellular_part
    GO:0044444_(0.19)_cytoplasmic_part
    GO:0043226_(0.18)_organelle
    GO:0044422_(0.17)_organelle_part
    GO:0043227_(0.17)_membrane-bounded_organelle
    GO:0098590_(0.16)_plasma_membrane_region
    GO:0016324_(0.15)_apical_plasma_membrane
    GO:0043229_(0.13)_intracellular_organelle
    GO:0044446_(0.12)_intracellular_organelle_part
    GO:0043231_(0.12)_intracellular_membrane-bounded
    organelle
    UniProt annotation:
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉◉○○

  • Testis:_20.45
  • Vagina:_16.40
  • Pituitary:_15.56
  • Cervix_-_Endocervix:_15.05
  • Cervix_-_Ectocervix:_14.95
  • Artery_-_Aorta:_14.94
  • Uterus:_13.99
  • Nerve_-_Tibial:_13.55
  • Skin_-_Sun_Exposed_(Lower_leg):_13.54
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_13.50
  • Thyroid:_13.34
  • Lung:_13.32
  • Artery_-_Coronary:_12.76
  • Esophagus_-_Mucosa:_12.60
  • Spleen:_11.89
  • Bladder:_11.68
  • Adipose_-_Subcutaneous:_11.65
  • Minor_Salivary_Gland:_11.48
  • Artery_-_Tibial:_11.30
  • Breast_-_Mammary_Tissue:_11.17
  • Fallopian_Tube:_11.10
  • Small_Intestine_-_Terminal_Ileum:_10.34
  • Adipose_-_Visceral_(Omentum):_10.30
  • Prostate:_10.28
  • Ovary:_10.28
  • Colon_-_Transverse:_10.26
  • Adrenal_Gland:_9.65
  • Cells_-_Transformed_fibroblasts:_9.58
  • Colon_-_Sigmoid:_9.47
  • Brain_-_Cerebellar_Hemisphere:_9.22
  • Stomach:_8.79
  • Esophagus_-_Gastroesophageal_Junction:_8.75
  • Brain_-_Cerebellum:_8.53
  • Cells_-_EBV-transformed_lymphocytes:_8.32
  • Esophagus_-_Muscularis:_7.81
  • Heart_-_Atrial_Appendage:_7.68
  • Muscle_-_Skeletal:_7.39
  • Brain_-_Hypothalamus:_5.84
  • Brain_-_Frontal_Cortex_(BA9):_5.68
  • Brain_-_Spinal_cord_(cervical_c-1):_5.61
  • Heart_-_Left_Ventricle:_5.41
  • Brain_-_Cortex:_4.77
  • Liver:_4.76
  • Whole_Blood:_4.71
  • Brain_-_Substantia_nigra:_4.66
  • Kidney_-_Cortex:_4.51
  • Pancreas:_4.34
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_4.15
  • Brain_-_Anterior_cingulate_cortex_(BA24):_4.02
  • Brain_-_Caudate_(basal_ganglia):_4.00
  • Brain_-_Hippocampus:_3.88
  • Brain_-_Amygdala:_3.54
  • Brain_-_Putamen_(basal_ganglia):_3.28
  • 60>NX_Q6UX52-1|CQ099_HUMAN Uncharacterized protein C17orf99 GN=C17orf99
    MGLPGLFCLAVLAASSFSKAREEEITPVVSIAYKVLEVFPKGRWVLITCC
    APQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFC
    WASSTSGAHVDSARLQMHWELWSKPVSELRANFTLQDRGAGPRVEMICQA
    SSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSDWFWCQAANN
    ANVQHSALTVVPPGGDQKMEDWQGPLESPILALPLYRSTRRLSEEEFGGF
    RIGNGEVRGRKAAAM


    chromosome location: 78146353-78166177 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0004872_(0.63)_receptor_activity
    GO:0004888_(0.56)_transmembrane_signaling_receptor
    activity
    GO:0003824_(0.54)_catalytic_activity
    GO:0004672_(0.53)_protein_kinase_activity
    GO:0019199_(0.50)_transmembrane_receptor_protein
    kinase_activity
    GO:0097367_(0.49)_carbohydrate_derivative_binding
    GO:0035639_(0.47)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.47)_adenyl_ribonucleotide_binding
    GO:0032550_(0.47)_purine_ribonucleoside_binding
    GO:0046983_(0.39)_protein_dimerization_activity
    GO:0072341_(0.25)_modified_amino_acid_binding
    GO:0005543_(0.25)_phospholipid_binding
    GO:0042802_(0.24)_identical_protein_binding
    GO:0005102_(0.21)_receptor_binding
    GO:0042803_(0.18)_protein_homodimerization
    activity
    BP:
    GO:0044699_(0.79)_single-organism_process
    GO:0009987_(0.76)_cellular_process
    GO:0044763_(0.75)_single-organism_cellular_process
    GO:0032502_(0.68)_developmental_process
    GO:0044767_(0.67)_single-organism_developmental
    process
    GO:0048869_(0.61)_cellular_developmental_process
    GO:0016043_(0.61)_cellular_component_organization
    GO:0009653_(0.60)_anatomical_structure
    morphogenesis
    GO:0006928_(0.58)_movement_of_cell_or_subcellular
    component
    GO:0065007_(0.56)_biological_regulation
    GO:0050789_(0.55)_regulation_of_biological_process
    GO:0048856_(0.54)_anatomical_structure_development
    GO:0030030_(0.54)_cell_projection_organization
    GO:0050794_(0.53)_regulation_of_cellular_process
    GO:0032989_(0.53)_cellular_component_morphogenesis
    CC:
    GO:0031224_(1.00)_intrinsic_component_of_membrane
    GO:0016020_(1.00)_membrane
    GO:0044464_(0.98)_cell_part
    GO:0016021_(0.95)_integral_component_of_membrane
    GO:0005886_(0.90)_plasma_membrane
    GO:0044459_(0.75)_plasma_membrane_part
    GO:0005887_(0.63)_integral_component_of_plasma
    membrane
    GO:0043226_(0.50)_organelle
    GO:0043227_(0.49)_membrane-bounded_organelle
    GO:0031982_(0.42)_vesicle
    GO:0097458_(0.41)_neuron_part
    GO:0044424_(0.41)_intracellular_part
    GO:0042995_(0.40)_cell_projection
    GO:0031988_(0.38)_membrane-bounded_vesicle
    GO:0009986_(0.38)_cell_surface
    UniProt annotation:
    GO:0002313_mature_B_cell_differentiation_involved
    in_immune_response
    GO:0005615_extracellular_space
    GO:2000558_positive_regulation_of_immunoglobulin
    production_in_mucosal_tissue
    GO:0005576_extracellular_region

    UniProt annotation score: ◉◉○○○

  • Cells_-_EBV-transformed_lymphocytes:_3.62
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_0.37
  • Whole_Blood:_0.36
  • Skin_-_Sun_Exposed_(Lower_leg):_0.32
  • Spleen:_0.20
  • Vagina:_0.20
  • Esophagus_-_Mucosa:_0.15
  • Fallopian_Tube:_0.11
  • Nerve_-_Tibial:_0.11
  • Ovary:_0.10
  • Lung:_0.10
  • Minor_Salivary_Gland:_0.09
  • Testis:_0.08
  • Small_Intestine_-_Terminal_Ileum:_0.08
  • Bladder:_0.07
  • Prostate:_0.06
  • Adipose_-_Subcutaneous:_0.05
  • Breast_-_Mammary_Tissue:_0.05
  • Uterus:_0.04
  • Cervix_-_Ectocervix:_0.04
  • Colon_-_Transverse:_0.04
  • Adipose_-_Visceral_(Omentum):_0.03
  • Esophagus_-_Gastroesophageal_Junction:_0.03
  • Brain_-_Spinal_cord_(cervical_c-1):_0.02
  • Colon_-_Sigmoid:_0.02
  • Brain_-_Substantia_nigra:_0.02
  • Esophagus_-_Muscularis:_0.02
  • Pituitary:_0.02
  • Kidney_-_Cortex:_0.02
  • Brain_-_Putamen_(basal_ganglia):_0.01
  • Brain_-_Caudate_(basal_ganglia):_0.01
  • Brain_-_Hypothalamus:_0.01
  • Liver:_0.01
  • Brain_-_Hippocampus:_0.01
  • Brain_-_Anterior_cingulate_cortex_(BA24):_0.01
  • Pancreas:_0.01
  • 61>NX_O43760-1|SNG2_HUMAN Synaptogyrin-2 GN=SYNGR2
    MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSN
    AHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATD
    RKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKDVLVGADSVRAAIT
    FSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYASYPGASV
    DNYQQPPFTQNAETTEGYQPPPVY


    chromosome location: 78168558-78173527 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0043169_(0.37)_cation_binding
    GO:0047485_(0.23)_protein_N-terminus_binding
    GO:0042169_(0.23)_SH2_domain_binding
    GO:0016462_(0.22)_pyrophosphatase_activity
    GO:0015405_(0.22)_P-P-bond-hydrolysis-driven
    transmembrane_transporter_activity
    BP:
    GO:0006810_(0.66)_transport
    GO:0051649_(0.64)_establishment_of_localization_in
    cell
    GO:0051641_(0.64)_cellular_localization
    GO:0006605_(0.52)_protein_targeting
    GO:0065007_(0.51)_biological_regulation
    GO:0050789_(0.51)_regulation_of_biological_process
    GO:0051049_(0.31)_regulation_of_transport
    GO:0032411_(0.26)_positive_regulation_of
    transporter_activity
    GO:0050794_(0.25)_regulation_of_cellular_process
    GO:0044699_(0.25)_single-organism_process
    GO:0048168_(0.20)_regulation_of_neuronal_synaptic
    plasticity
    GO:0048172_(0.19)_regulation_of_short-term
    neuronal_synaptic_plasticity
    GO:0048169_(0.19)_regulation_of_long-term_neuronal
    synaptic_plasticity
    GO:0044765_(0.16)_single-organism_transport
    GO:0048489_(0.12)_synaptic_vesicle_transport
    CC:
    GO:0031594_(1.00)_neuromuscular_junction
    GO:0030672_(1.00)_synaptic_vesicle_membrane
    GO:0031988_(0.13)_membrane-bounded_vesicle
    GO:0008021_(0.10)_synaptic_vesicle
    GO:0070062_(0.06)_extracellular_exosome
    GO:0016021_(0.06)_integral_component_of_membrane
    GO:0043195_(0.01)_terminal_bouton
    UniProt annotation:
    May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane. {ECO:0000250|UniProtKB:O54980}. (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication. {ECO:0000269|PubMed:27226560}.

    GO:0030672_synaptic_vesicle_membrane
    GO:0005515_protein_binding
    GO:0070062_extracellular_exosome
    GO:0016021_integral_component_of_membrane
    GO:0048499_synaptic_vesicle_membrane_organization
    GO:0045055_regulated_exocytosis
    GO:0031594_neuromuscular_junction
    GO:0030054_cell_junction
    GO:0005811_lipid_droplet
    GO:0031410_cytoplasmic_vesicle
    GO:0045202_synapse
    GO:0016020_membrane
    GO:0008021_synaptic_vesicle
    GO:0030659_cytoplasmic_vesicle_membrane

    UniProt annotation score: ◉◉◉◉◉

    NextProt annotation:
    (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication.

    GO:0045055_regulated_exocytosis
    GO:0048499_synaptic_vesicle_membrane_organization
    GO:0005515_protein_binding
    High:
  • prostate_(glandular_cells)
    Medium:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • colon_(glandular_cells)
  • gallbladder_(glandular_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells;_squamous_epithelial_cells)
  • thyroid_gland_(glandular_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_2_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • duodenum_(glandular_cells)
  • cerebral_cortex_(endothelial_cells)
  • lymph_node_(germinal_center_cells;_non-
    germinal_center_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • small_intestine_(glandular_cells)
  • breast_(glandular_cells)
  • rectum_(glandular_cells)
  • pancreas_(exocrine_glandular_cells)
  • placenta_(trophoblastic_cells)
  • fallopian_tube_(glandular_cells)
  • spleen_(cells_in_red_pulp;_cells_in_white
    pulp)
  • appendix_(glandular_cells;_lymphoid_tissue)
  • nasopharynx_(respiratory_epithelial_cells)
  • lung_(macrophages)
  • skin_2_(epidermal_cells)
    Low:
  • kidney_(cells_in_tubules)
  • bone_marrow_(hematopoietic_cells)
  • skin_1_(keratinocytes;_melanocytes)
  • endometrium_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • breast_(myoepithelial_cells)
  • esophagus_(squamous_epithelial_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • cerebral_cortex_(glial_cells)
  • cervix,_uterine_(squamous_epithelial_cells)
  • Cells_-_EBV-transformed_lymphocytes:_348.30
  • Lung:_133.40
  • Spleen:_112.15
  • Minor_Salivary_Gland:_107.80
  • Prostate:_105.60
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_100.60
  • Skin_-_Sun_Exposed_(Lower_leg):_100.50
  • Artery_-_Aorta:_90.22
  • Muscle_-_Skeletal:_89.39
  • Artery_-_Coronary:_80.53
  • Esophagus_-_Gastroesophageal_Junction:_78.02
  • Brain_-_Spinal_cord_(cervical_c-1):_75.15
  • Small_Intestine_-_Terminal_Ileum:_75.04
  • Esophagus_-_Mucosa:_74.43
  • Esophagus_-_Muscularis:_74.11
  • Pituitary:_73.59
  • Whole_Blood:_71.61
  • Stomach:_70.48
  • Breast_-_Mammary_Tissue:_69.88
  • Colon_-_Transverse:_67.47
  • Vagina:_64.60
  • Nerve_-_Tibial:_64.31
  • Artery_-_Tibial:_62.90
  • Bladder:_62.57
  • Adipose_-_Subcutaneous:_62.42
  • Thyroid:_61.09
  • Fallopian_Tube:_57.39
  • Cervix_-_Endocervix:_53.84
  • Adipose_-_Visceral_(Omentum):_53.40
  • Pancreas:_51.82
  • Uterus:_50.29
  • Cervix_-_Ectocervix:_48.41
  • Kidney_-_Cortex:_39.12
  • Ovary:_37.52
  • Heart_-_Left_Ventricle:_37.21
  • Heart_-_Atrial_Appendage:_34.36
  • Adrenal_Gland:_32.48
  • Testis:_29.67
  • Brain_-_Cerebellum:_29.67
  • Colon_-_Sigmoid:_29.24
  • Brain_-_Cerebellar_Hemisphere:_28.91
  • Liver:_26.21
  • Brain_-_Substantia_nigra:_24.15
  • Brain_-_Hippocampus:_19.41
  • Brain_-_Hypothalamus:_17.94
  • Brain_-_Putamen_(basal_ganglia):_14.90
  • Brain_-_Caudate_(basal_ganglia):_13.72
  • Brain_-_Amygdala:_12.79
  • Brain_-_Cortex:_12.24
  • Brain_-_Frontal_Cortex_(BA9):_11.28
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_11.27
  • Brain_-_Anterior_cingulate_cortex_(BA24):_8.62
  • Cells_-_Transformed_fibroblasts:_8.35
  • 62>NX_Q96MC4-1|C295L_HUMAN CEP295 N-terminal-like protein GN=CEP295NL
    MCSGWSSSVIWRHTQFAVERCGFCGSSGPGAPLEPSTLGSKHLPWEAVSA
    GFADRNRNMDGAMWLSLCPDNEDLLWRKKHKLLQARGKGDLALQRRADAK
    LWKNYQLQRLAEELRRGYQEAQHLHVGGLDRLQSARLLGWGGGRARENEP
    DSQGPIQRRSARPPRAKEKHRAALSEERSCREELGQQHPRHSRPRKTAAS
    PEKPQTTKATGRMNSHLAPPEKRKGRPEPSTKSGGGRCAIHPRRSKGADL
    ERSNPLVAAVGEIGLVEEKEKGTARAGRRQLGKGAVCFVPALTSRSQGQS
    LEGKLRDLGQLWPADSSCRREAVSPASQCTLREKNKWQKELELAFEELFN
    INRKLKKHLCLYLALKPRMDQRPGEGHAFSEMQECGAGTPRGKKMADPEM
    LPAGEPRSPAEEEAQQAASKTDLKTFMGKAQNQKYQGTVKPTFRNGSQTL
    SPEAGIFINKEDSLLYSTESGQETPKLGTLAEGSLQLHLQDQADRVGSTA
    SRQRQKAEMEQRRQKQLESLEQMEHPDMSLEIHYKAELEKERREQRRARL
    AHLKSSSTRAQERERGSELSTTSPSGTSLADDDRHSQMIRDQQQQILQQN
    RLHKQFLEEARKCLREFQNIC


    chromosome location: 78870910-78903217 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • MF:
    GO:0003824_(0.63)_catalytic_activity
    GO:0016740_(0.50)_transferase_activity
    GO:0036094_(0.45)_small_molecule_binding
    GO:1901981_(0.44)_phosphatidylinositol_phosphate
    binding
    GO:0030234_(0.44)_enzyme_regulator_activity
    GO:0033218_(0.43)_amide_binding
    GO:0030246_(0.43)_carbohydrate_binding
    GO:0010485_(0.43)_H4_histone_acetyltransferase
    activity
    GO:0008375_(0.43)_acetylglucosaminyltransferase
    activity
    GO:0016787_(0.21)_hydrolase_activity
    GO:0017111_(0.20)_nucleoside-triphosphatase
    activity
    GO:0016887_(0.19)_ATPase_activity
    GO:0003774_(0.16)_motor_activity
    GO:0005198_(0.12)_structural_molecule_activity
    GO:0003777_(0.12)_microtubule_motor_activity
    BP:
    GO:0065007_(0.75)_biological_regulation
    GO:0050789_(0.72)_regulation_of_biological_process
    GO:0009987_(0.72)_cellular_process
    GO:0050794_(0.71)_regulation_of_cellular_process
    GO:0044699_(0.67)_single-organism_process
    GO:0044763_(0.65)_single-organism_cellular_process
    GO:0051128_(0.64)_regulation_of_cellular_component
    organization
    GO:0048518_(0.63)_positive_regulation_of
    biological_process
    GO:0048522_(0.62)_positive_regulation_of_cellular
    process
    GO:0033043_(0.61)_regulation_of_organelle
    organization
    GO:0010638_(0.58)_positive_regulation_of_organelle
    organization
    GO:0016043_(0.55)_cellular_component_organization
    GO:0032502_(0.51)_developmental_process
    GO:0044767_(0.49)_single-organism_developmental
    process
    GO:0051179_(0.48)_localization
    CC:
    GO:0044464_(1.00)_cell_part
    GO:0044424_(0.97)_intracellular_part
    GO:0044444_(0.83)_cytoplasmic_part
    GO:0043226_(0.83)_organelle
    GO:0044422_(0.81)_organelle_part
    GO:0044446_(0.80)_intracellular_organelle_part
    GO:0043229_(0.74)_intracellular_organelle
    GO:0043234_(0.63)_protein_complex
    GO:0043227_(0.59)_membrane-bounded_organelle
    GO:0044430_(0.58)_cytoskeletal_part
    GO:0043231_(0.57)_intracellular_membrane-bounded
    organelle
    GO:0005737_(0.53)_cytoplasm
    GO:0016020_(0.44)_membrane
    GO:0005829_(0.43)_cytosol
    GO:0043232_(0.42)_intracellular_non-membrane-
    bounded_organelle
    UniProt annotation:
    GO:0005929_cilium
    GO:0042995_cell_projection

    UniProt annotation score: ◉◉○○○

    63>NX_Q96N21-1|AP4AT_HUMAN AP-4 complex accessory subunit Tepsin GN=TEPSIN
    MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSS
    QCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQE
    AAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLGTPPA
    TGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNS
    SQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLV
    RTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRA
    LCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEA
    SCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVS
    SRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIP
    GGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAP
    QTSSQRTAAKEPPGSEPSAFAFLNA


    chromosome location: 81228277-81239091 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • MF:
    GO:0003824_(0.47)_catalytic_activity
    GO:0043167_(0.43)_ion_binding
    GO:0043169_(0.42)_cation_binding
    GO:0016740_(0.15)_transferase_activity
    GO:0016787_(0.11)_hydrolase_activity
    GO:0005198_(0.11)_structural_molecule_activity
    GO:1901363_(0.10)_heterocyclic_compound_binding
    GO:0097159_(0.10)_organic_cyclic_compound_binding
    GO:0016772_(0.09)_transferase_activity,
    transferring_phosphorus-containing_groups
    GO:0044877_(0.08)_macromolecular_complex_binding
    GO:0003676_(0.08)_nucleic_acid_binding
    GO:0098772_(0.07)_molecular_function_regulator
    GO:0005215_(0.07)_transporter_activity
    GO:0004872_(0.07)_receptor_activity
    GO:0001104_(0.07)_RNA_polymerase_II_transcription
    cofactor_activity
    BP:
    GO:0009987_(0.61)_cellular_process
    GO:0044699_(0.53)_single-organism_process
    GO:0065007_(0.52)_biological_regulation
    GO:0050789_(0.44)_regulation_of_biological_process
    GO:0050794_(0.42)_regulation_of_cellular_process
    GO:0044763_(0.41)_single-organism_cellular_process
    GO:0044767_(0.27)_single-organism_developmental
    process
    GO:0071704_(0.25)_organic_substance_metabolic
    process
    GO:0016043_(0.25)_cellular_component_organization
    GO:0044238_(0.24)_primary_metabolic_process
    GO:0044237_(0.24)_cellular_metabolic_process
    GO:0051179_(0.23)_localization
    GO:0044260_(0.22)_cellular_macromolecule_metabolic
    process
    GO:0007165_(0.22)_signal_transduction
    GO:0006810_(0.22)_transport
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0032991_(0.64)_macromolecular_complex
    GO:0043234_(0.63)_protein_complex
    GO:0043226_(0.63)_organelle
    GO:0043229_(0.61)_intracellular_organelle
    GO:0005737_(0.60)_cytoplasm
    GO:0044422_(0.49)_organelle_part
    GO:0044446_(0.48)_intracellular_organelle_part
    GO:0043227_(0.45)_membrane-bounded_organelle
    GO:0044444_(0.44)_cytoplasmic_part
    GO:0043231_(0.42)_intracellular_membrane-bounded
    organelle
    GO:0016020_(0.41)_membrane
    GO:0044428_(0.38)_nuclear_part
    GO:0043232_(0.33)_intracellular_non-membrane-
    bounded_organelle
    GO:1902494_(0.32)_catalytic_complex
    UniProt annotation:
    Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. {ECO:0000305|PubMed:22472443, ECO:0000305|PubMed:26542808}.

    GO:0030124_AP-4_adaptor_complex
    GO:0005794_Golgi_apparatus
    GO:0030662_coated_vesicle_membrane
    GO:0032588_trans-Golgi_network_membrane
    GO:0031312_extrinsic_component_of_organelle
    membrane
    GO:0005515_protein_binding
    GO:0005737_cytoplasm
    GO:0031965_nuclear_membrane
    GO:0016607_nuclear_speck
    GO:0031410_cytoplasmic_vesicle
    GO:0016020_membrane
    GO:0005829_cytosol

    UniProt annotation score: ◉◉◉◉◉

    NextProt annotation:
    Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.

    GO:0005515_protein_binding
    64>NX_Q5BKU9-1|OXLD1_HUMAN Oxidoreductase-like domain-containing protein 1 GN=OXLD1
    MLLRRVVEGGRAVAAAVRGSGARRFSSPDCCQRLPGGGSFLQRHHPGAQA
    PDGRRKFGTDHVEVGSQAGADGTRPPKASLPPELQPPTNCCMSGCPNCVW
    VEYADRLLQHFQDGGERALAALEEHVADENLKAFLRMEIRLHTRCGG


    chromosome location: 81665036-81666635 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0003824_(0.94)_catalytic_activity
    GO:0016491_(0.87)_oxidoreductase_activity
    GO:0000166_(0.82)_nucleotide_binding
    GO:0071949_(0.73)_FAD_binding
    GO:0004128_(0.73)_cytochrome-b5_reductase
    activity,_acting_on_NAD(P)H
    GO:0016211_(0.52)_ammonia_ligase_activity
    GO:0035639_(0.33)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.33)_adenyl_ribonucleotide_binding
    GO:0032550_(0.33)_purine_ribonucleoside_binding
    GO:0030586_(0.14)_[methionine_synthase]_reductase
    activity
    BP:
    GO:0015701_(0.90)_bicarbonate_transport
    GO:0009084_(0.53)_glutamine_family_amino_acid
    biosynthetic_process
    GO:0008652_(0.53)_cellular_amino_acid_biosynthetic
    process
    GO:0006541_(0.53)_glutamine_metabolic_process
    GO:0071941_(0.34)_nitrogen_cycle_metabolic_process
    CC:
    GO:0043231_(1.00)_intracellular_membrane-bounded
    organelle
    GO:0044444_(0.94)_cytoplasmic_part
    GO:0005739_(0.90)_mitochondrion
    GO:0005737_(0.66)_cytoplasm
    GO:0016020_(0.19)_membrane
    GO:0005634_(0.18)_nucleus
    GO:0005886_(0.16)_plasma_membrane
    GO:0005829_(0.12)_cytosol
    GO:0044428_(0.11)_nuclear_part
    GO:0043234_(0.08)_protein_complex
    GO:0005654_(0.08)_nucleoplasm
    GO:0070062_(0.04)_extracellular_exosome
    GO:0045202_(0.04)_synapse
    GO:0043197_(0.04)_dendritic_spine
    GO:0034399_(0.04)_nuclear_periphery

    UniProt annotation score: ◉○○○○

  • Testis:_62.40
  • Spleen:_58.87
  • Cells_-_EBV-transformed_lymphocytes:_51.45
  • Prostate:_48.01
  • Cells_-_Transformed_fibroblasts:_42.18
  • Thyroid:_41.66
  • Skin_-_Sun_Exposed_(Lower_leg):_41.25
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_39.93
  • Pituitary:_37.22
  • Adrenal_Gland:_34.71
  • Nerve_-_Tibial:_34.24
  • Fallopian_Tube:_34.19
  • Bladder:_33.59
  • Breast_-_Mammary_Tissue:_32.95
  • Uterus:_32.84
  • Lung:_32.09
  • Small_Intestine_-_Terminal_Ileum:_31.68
  • Stomach:_30.27
  • Vagina:_29.77
  • Esophagus_-_Mucosa:_29.77
  • Brain_-_Cerebellar_Hemisphere:_29.26
  • Cervix_-_Ectocervix:_29.11
  • Artery_-_Coronary:_28.88
  • Minor_Salivary_Gland:_28.60
  • Kidney_-_Cortex:_28.34
  • Esophagus_-_Muscularis:_28.12
  • Adipose_-_Subcutaneous:_28.09
  • Esophagus_-_Gastroesophageal_Junction:_27.69
  • Brain_-_Cerebellum:_27.46
  • Colon_-_Sigmoid:_27.39
  • Cervix_-_Endocervix:_27.35
  • Ovary:_27.22
  • Artery_-_Aorta:_26.48
  • Colon_-_Transverse:_26.32
  • Brain_-_Frontal_Cortex_(BA9):_24.69
  • Brain_-_Spinal_cord_(cervical_c-1):_23.95
  • Brain_-_Hypothalamus:_23.11
  • Brain_-_Cortex:_22.87
  • Adipose_-_Visceral_(Omentum):_22.49
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_22.42
  • Artery_-_Tibial:_21.57
  • Brain_-_Caudate_(basal_ganglia):_20.83
  • Brain_-_Substantia_nigra:_20.35
  • Brain_-_Putamen_(basal_ganglia):_20.14
  • Brain_-_Anterior_cingulate_cortex_(BA24):_20.13
  • Brain_-_Hippocampus:_19.09
  • Brain_-_Amygdala:_18.07
  • Liver:_16.45
  • Whole_Blood:_16.03
  • Heart_-_Atrial_Appendage:_14.65
  • Pancreas:_13.57
  • Muscle_-_Skeletal:_11.88
  • Heart_-_Left_Ventricle:_11.73
  • 65>NX_Q2TAC2-1|CCD57_HUMAN Coiled-coil domain-containing protein 57 GN=CCDC57
    MLPLGSEPALNELLLRKEEEWRALQAHRTQLQEAALQDTRSQLEEAQGKL
    RCLQEDFVYNLQVLEERDLELERYDAAFAQAREWEEARRAEVSELKIEAA
    KLRQALAREARKVEELQQQQQLAFQEHRLELERVHSDKNGEIDHHREQYE
    NLKWTLERKLEELDGELALQRQELLLEFESKMRKREHEFRLQADNMSNTA
    LSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQ
    DLEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLV
    AVKGAHVEQLQELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAID
    QLREDASTVKSAWDAQIAQLSKEMVSRDLQIQTLQEEEVKLKAQVARSQQ
    DIERYKQQLSLAVERERSLERDQVQLGLDWQRRCDDIERDQIQKSEALIQ
    GLSMAKSQVAAKLQETEQALQEQEVVLKAVTLERDQAVQALRMHGLPRPG
    AQMLLRQHEEEISKDFPSSEIQRLREQNTSLRNAIAQMRKEMEALSHQIP
    PPIQTAAESTDANQPDPEAGGDAATPDYVLALEAEIRTLKHKFKTLEKHL
    EDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSVQAGQAGGSVQ
    AGPVSSGLALRKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVD
    QVHLEVLELRKQVAELGKHLRIAQHGGAEPSGRKQPPASDAVALGREQDA
    KSAEDEAPSRHLGKHQPRSAQVGSRLDALQGPKTQHSIHTVTCKSPRQKE
    DRSPKPPQAPQHPEEHGRQSHSSSSFASGTLQDMWRLLDLGSSPSGVTSQ
    GDSTPELPAPPAADRRPVKMQAGIATPGMKTAAQAKAKTTGASRSHPAKA
    KGCQRPPKIRNYNIMD


    chromosome location: 82101460-82212830 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • Human Protein Atlas
  • MF:
    GO:0097367_(0.44)_carbohydrate_derivative_binding
    GO:0035639_(0.41)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.41)_adenyl_ribonucleotide_binding
    GO:0032550_(0.41)_purine_ribonucleoside_binding
    GO:0052813_(0.31)_phosphatidylinositol
    bisphosphate_kinase_activity
    GO:0052742_(0.31)_phosphatidylinositol_kinase
    activity
    GO:0035004_(0.31)_phosphatidylinositol_3-kinase
    activity
    GO:0016307_(0.31)_phosphatidylinositol_phosphate
    kinase_activity
    GO:0004872_(0.08)_receptor_activity
    GO:0008201_(0.05)_heparin_binding
    BP:
    GO:0009987_(0.91)_cellular_process
    GO:0044699_(0.81)_single-organism_process
    GO:0044763_(0.77)_single-organism_cellular_process
    GO:0065007_(0.61)_biological_regulation
    GO:0050794_(0.59)_regulation_of_cellular_process
    GO:0016043_(0.56)_cellular_component_organization
    GO:0048518_(0.50)_positive_regulation_of
    biological_process
    GO:0060255_(0.48)_regulation_of_macromolecule
    metabolic_process
    GO:0010604_(0.46)_positive_regulation_of
    macromolecule_metabolic_process
    GO:0035556_(0.43)_intracellular_signal
    transduction
    GO:0010468_(0.43)_regulation_of_gene_expression
    GO:0048017_(0.41)_inositol_lipid-mediated
    signaling
    GO:0071704_(0.40)_organic_substance_metabolic
    process
    GO:0044238_(0.40)_primary_metabolic_process
    GO:0044237_(0.40)_cellular_metabolic_process
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0016020_(1.00)_membrane
    GO:0043234_(0.90)_protein_complex
    GO:0044425_(0.86)_membrane_part
    GO:0005942_(0.85)_phosphatidylinositol_3-kinase
    complex
    GO:0043226_(0.77)_organelle
    GO:0044444_(0.76)_cytoplasmic_part
    GO:0043229_(0.75)_intracellular_organelle
    GO:0005737_(0.74)_cytoplasm
    GO:0044446_(0.72)_intracellular_organelle_part
    GO:0005886_(0.69)_plasma_membrane
    GO:0043227_(0.67)_membrane-bounded_organelle
    GO:0043231_(0.66)_intracellular_membrane-bounded
    organelle
    GO:0005829_(0.60)_cytosol
    GO:0044430_(0.47)_cytoskeletal_part
    UniProt annotation:
    GO:0005515_protein_binding

    UniProt annotation score: ◉◉◉◉◉

    NextProt annotation:
    GO:0005515_protein_binding
    High:
  • stomach_2_(glandular_cells)
  • stomach_1_(glandular_cells)
  • seminal_vesicle_(glandular_cells)
  • colon_(endothelial_cells;_glandular_cells)
  • gallbladder_(glandular_cells)
  • esophagus_(squamous_epithelial_cells)
  • kidney_(cells_in_glomeruli;_cells_in_tubules)
  • testis_(cells_in_seminiferous_ducts)
  • tonsil_(squamous_epithelial_cells)
  • vagina_(squamous_epithelial_cells)
  • epididymis_(glandular_cells)
  • adrenal_gland_(glandular_cells)
  • endometrium_1_(glandular_cells)
  • thyroid_gland_(glandular_cells)
  • salivary_gland_(glandular_cells)
  • heart_muscle_(myocytes)
  • cerebral_cortex_(neuronal_cells)
  • lymph_node_(non-germinal_center_cells)
  • placenta_(trophoblastic_cells)
  • bronchus_(respiratory_epithelial_cells)
  • parathyroid_gland_(glandular_cells)
  • urinary_bladder_(urothelial_cells)
  • appendix_(glandular_cells)
  • liver_(bile_duct_cells)
  • rectum_(glandular_cells)
  • prostate_(glandular_cells)
  • cervix,_uterine_(glandular_cells;_squamous
    epithelial_cells)
  • duodenum_(glandular_cells)
  • cerebellum_(cells_in_molecular_layer;_Purkinje
    cells)
  • fallopian_tube_(glandular_cells)
  • skin_2_(epidermal_cells)
  • small_intestine_(glandular_cells)
  • nasopharynx_(respiratory_epithelial_cells)
  • oral_mucosa_(squamous_epithelial_cells)
  • skin_1_(keratinocytes;_melanocytes)
  • breast_(glandular_cells;_myoepithelial_cells)
    Medium:
  • colon_(peripheral_nerve/ganglion)
  • smooth_muscle_(smooth_muscle_cells)
  • testis_(Leydig_cells)
  • caudate_(neuronal_cells)
  • tonsil_(germinal_center_cells;_non-germinal
    center_cells)
  • endometrium_1_(cells_in_endometrial_stroma)
  • endometrium_2_(cells_in_endometrial_stroma;
    glandular_cells)
  • cerebral_cortex_(endothelial_cells)
  • lymph_node_(germinal_center_cells)
  • hippocampus_(neuronal_cells)
  • skeletal_muscle_(myocytes)
  • appendix_(lymphoid_tissue)
  • breast_(adipocytes)
  • pancreas_(exocrine_glandular_cells;_islets_of
    Langerhans)
  • spleen_(cells_in_white_pulp)
  • bone_marrow_(hematopoietic_cells)
  • soft_tissue_2_(adipocytes;_fibroblasts)
  • soft_tissue_1_(adipocytes;_fibroblasts;
    peripheral_nerve)
  • lung_(macrophages;_pneumocytes)
  • ovary_(ovarian_stroma_cells)
  • skin_1_(fibroblasts;_Langerhans)
  • liver_(hepatocytes)
    Low:
  • cerebellum_(cells_in_granular_layer)
  • hippocampus_(glial_cells)
  • caudate_(glial_cells)
  • spleen_(cells_in_red_pulp)
  • soft_tissue_1_(chondrocytes)
  • soft_tissue_2_(peripheral_nerve)
  • ovary_(follicle_cells)
  • cerebral_cortex_(glial_cells)
  • Thyroid:_27.31
  • Brain_-_Cerebellum:_23.59
  • Pituitary:_22.78
  • Testis:_21.43
  • Brain_-_Cerebellar_Hemisphere:_20.41
  • Prostate:_19.98
  • Ovary:_19.02
  • Uterus:_18.12
  • Fallopian_Tube:_17.73
  • Cervix_-_Endocervix:_13.96
  • Lung:_13.74
  • Cervix_-_Ectocervix:_13.68
  • Nerve_-_Tibial:_13.09
  • Minor_Salivary_Gland:_12.21
  • Bladder:_12.18
  • Breast_-_Mammary_Tissue:_11.65
  • Colon_-_Sigmoid:_10.78
  • Vagina:_9.88
  • Spleen:_9.00
  • Cells_-_Transformed_fibroblasts:_8.94
  • Small_Intestine_-_Terminal_Ileum:_8.89
  • Adrenal_Gland:_8.88
  • Kidney_-_Cortex:_8.82
  • Stomach:_8.39
  • Esophagus_-_Muscularis:_7.86
  • Esophagus_-_Gastroesophageal_Junction:_7.77
  • Colon_-_Transverse:_7.59
  • Adipose_-_Subcutaneous:_7.51
  • Brain_-_Cortex:_7.32
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_7.03
  • Skin_-_Sun_Exposed_(Lower_leg):_6.98
  • Artery_-_Coronary:_6.81
  • Artery_-_Aorta:_6.55
  • Adipose_-_Visceral_(Omentum):_6.44
  • Brain_-_Frontal_Cortex_(BA9):_5.85
  • Cells_-_EBV-transformed_lymphocytes:_5.77
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_5.52
  • Pancreas:_5.45
  • Whole_Blood:_5.44
  • Artery_-_Tibial:_5.33
  • Brain_-_Caudate_(basal_ganglia):_4.99
  • Esophagus_-_Mucosa:_4.31
  • Brain_-_Hypothalamus:_4.23
  • Brain_-_Anterior_cingulate_cortex_(BA24):_4.18
  • Brain_-_Putamen_(basal_ganglia):_4.11
  • Liver:_3.67
  • Brain_-_Hippocampus:_3.26
  • Brain_-_Amygdala:_3.04
  • Brain_-_Spinal_cord_(cervical_c-1):_3.03
  • Heart_-_Atrial_Appendage:_2.95
  • Brain_-_Substantia_nigra:_2.35
  • Muscle_-_Skeletal:_2.22
  • Heart_-_Left_Ventricle:_1.47
  • 66>NX_Q9BQA9-1|CQ062_HUMAN Uncharacterized protein C17orf62 GN=C17orf62
    MYLQVETRTSSRLHLKRAPGIRSWSLLVGILSIGLAAAYYSGDSLGWKLF
    YVTGCLFVAVQNLEDWEEAIFDKSTGKVVLKTFSLYKKLLTLFRAGHDQV
    VVLLHDVRDVSVEEEKVRYFGKGYMVVLRLATGFSHPLTQSAVMGHRSDV
    EAIAKLITSFLELHCLESPTELSQSSDSEAGDPASQS


    chromosome location: 82442589-82450829 (17q25.3)

    Database cross references:
  • UniProt
  • NextProt
  • QuickGO
  • GTEx Portal
  • MF:
    GO:0035639_(0.57)_purine_ribonucleoside
    triphosphate_binding
    GO:0032559_(0.57)_adenyl_ribonucleotide_binding
    GO:0032550_(0.57)_purine_ribonucleoside_binding
    GO:0051427_(0.37)_hormone_receptor_binding
    GO:0031701_(0.37)_angiotensin_receptor_binding
    GO:0005126_(0.37)_cytokine_receptor_binding
    GO:0004672_(0.37)_protein_kinase_activity
    BP:
    GO:0044351_(0.83)_macropinocytosis
    GO:0048870_(0.32)_cell_motility
    GO:0048869_(0.32)_cellular_developmental_process
    GO:0046777_(0.32)_protein_autophosphorylation
    GO:0018108_(0.32)_peptidyl-tyrosine
    phosphorylation
    GO:0008283_(0.32)_cell_proliferation
    GO:0007165_(0.32)_signal_transduction
    GO:0006955_(0.32)_immune_response
    GO:0006952_(0.32)_defense_response
    CC:
    GO:0044424_(1.00)_intracellular_part
    GO:0044446_(0.95)_intracellular_organelle_part
    GO:0043226_(0.95)_organelle
    GO:0043229_(0.89)_intracellular_organelle
    GO:0044444_(0.84)_cytoplasmic_part
    GO:0043232_(0.79)_intracellular_non-membrane-
    bounded_organelle
    GO:0044430_(0.74)_cytoskeletal_part
    GO:0043227_(0.74)_membrane-bounded_organelle
    GO:0005856_(0.74)_cytoskeleton
    GO:0005737_(0.74)_cytoplasm
    GO:0043231_(0.68)_intracellular_membrane-bounded
    organelle
    GO:0005874_(0.68)_microtubule
    GO:0005829_(0.68)_cytosol
    GO:0005871_(0.63)_kinesin_complex
    GO:0016020_(0.53)_membrane
    UniProt annotation:
    GO:0005515_protein_binding
    GO:0016020_membrane
    GO:0016021_integral_component_of_membrane

    UniProt annotation score: ◉◉○○○

    NextProt annotation:
    GO:0005515_protein_binding
  • Whole_Blood:_173.20
  • Spleen:_169.90
  • Cells_-_EBV-transformed_lymphocytes:_118.10
  • Cervix_-_Endocervix:_65.07
  • Lung:_59.58
  • Prostate:_58.26
  • Nerve_-_Tibial:_57.70
  • Fallopian_Tube:_52.90
  • Uterus:_49.19
  • Bladder:_48.54
  • Small_Intestine_-_Terminal_Ileum:_48.16
  • Ovary:_46.64
  • Thyroid:_43.98
  • Adipose_-_Subcutaneous:_43.76
  • Cervix_-_Ectocervix:_43.38
  • Artery_-_Aorta:_42.93
  • Artery_-_Coronary:_42.37
  • Breast_-_Mammary_Tissue:_42.05
  • Pituitary:_41.88
  • Cells_-_Transformed_fibroblasts:_41.58
  • Adipose_-_Visceral_(Omentum):_39.31
  • Brain_-_Spinal_cord_(cervical_c-1):_37.67
  • Vagina:_37.64
  • Minor_Salivary_Gland:_33.43
  • Artery_-_Tibial:_33.41
  • Colon_-_Transverse:_32.48
  • Adrenal_Gland:_31.39
  • Esophagus_-_Muscularis:_31.15
  • Colon_-_Sigmoid:_30.67
  • Kidney_-_Cortex:_30.40
  • Esophagus_-_Gastroesophageal_Junction:_30.18
  • Stomach:_30.14
  • Skin_-_Sun_Exposed_(Lower_leg):_29.32
  • Esophagus_-_Mucosa:_28.81
  • Liver:_27.49
  • Skin_-_Not_Sun_Exposed_(Suprapubic):_27.34
  • Testis:_27.24
  • Brain_-_Cerebellum:_26.85
  • Brain_-_Cerebellar_Hemisphere:_23.45
  • Brain_-_Substantia_nigra:_21.93
  • Brain_-_Hypothalamus:_20.80
  • Brain_-_Cortex:_20.49
  • Brain_-_Nucleus_accumbens_(basal_ganglia):_20.29
  • Brain_-_Caudate_(basal_ganglia):_19.67
  • Brain_-_Putamen_(basal_ganglia):_18.18
  • Brain_-_Frontal_Cortex_(BA9):_18.09
  • Pancreas:_17.96
  • Brain_-_Amygdala:_16.34
  • Brain_-_Hippocampus:_16.02
  • Brain_-_Anterior_cingulate_cortex_(BA24):_13.66
  • Heart_-_Atrial_Appendage:_13.43
  • Heart_-_Left_Ventricle:_8.99
  • Muscle_-_Skeletal:_6.51