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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide Y receptor type 5
Species	Mus musculus (Mouse)
Gene	Npy5r
Synonym	food intake receptor neuropeptide Y receptor type 5 NPY-Y5 receptor NPY5-R NPYY5-R Y5 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
UniProt	O70342
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3802
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1956848
Molecular formula	C19H21N3O4S
IUPAC name	5-ethylsulfonyl-N-(4-morpholin-4-ylphenyl)-1,3-benzoxazol-2-amine
Molecular weight	387.454
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.0
Synonyms	BDBM50365425
Inchi Key	MDPFEFWECSNFRH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21N3O4S/c1-2-27(23,24)16-7-8-18-17(13-16)21-19(26-18)20-14-3-5-15(6-4-14)22-9-11-25-12-10-22/h3-8,13H,2,9-12H2,1H3,(H,20,21)
PubChem CID	57391274
ChEMBL	CHEMBL1956848
IUPHAR	N/A
BindingDB	50365425
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	219.0 nM	PMID22300657	BindingDB,ChEMBL

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