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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide Y receptor type 5
Species	Mus musculus (Mouse)
Gene	Npy5r
Synonym	food intake receptor neuropeptide Y receptor type 5 NPY-Y5 receptor NPY5-R NPYY5-R Y5 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
UniProt	O70342
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3802
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1956845
Molecular formula	C16H13F3N2O3S
IUPAC name	5-ethylsulfonyl-N-[2-(trifluoromethyl)phenyl]-1,3-benzoxazol-2-amine
Molecular weight	370.346
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.1
Synonyms	ZINC12540713 1088166-92-0 MolPort-009-215-960 AKOS034448304 5-(ethanesulfonyl)-N-[2-(trifluoromethyl)phenyl]-1,3-benzoxazol-2-amine Z55889539 BDBM50365421 MCULE-8422810881 [ Show all ]
Inchi Key	BTWIYBIENHHQGR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H13F3N2O3S/c1-2-25(22,23)10-7-8-14-13(9-10)21-15(24-14)20-12-6-4-3-5-11(12)16(17,18)19/h3-9H,2H2,1H3,(H,20,21)
PubChem CID	25346017
ChEMBL	CHEMBL1956845
IUPHAR	N/A
BindingDB	50365421
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<10000.0 nM	PMID22300657	BindingDB,ChEMBL

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