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GPCR

NameDelta-type opioid receptor
SpeciesMus musculus (Mouse)
GeneOprd1
SynonymOP1
MSL-2
K56
DOR-1
DOR
[ Show all ]
DiseaseN/A for non-human GPCRs
Length372
Amino acid sequenceMELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
UniProtP32300
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3222
IUPHAR317
DrugBankN/A

Ligand

Name(2E,4E)-N-isobutyltetradeca-2,4-dienamide
Molecular formulaC18H33NO
IUPAC name(2E,4E)-N-(2-methylpropyl)tetradeca-2,4-dienamide
Molecular weight279.468
Hydrogen bond acceptor1
Hydrogen bond donor1
XlogP6.6
SynonymsN-(2-Methylpropyl)-2,4-tetradecadienamide
2,4-Tetradecadienamide, N-(2-methylpropyl)-, (E,E)-
N-Isobutyl-(2E,4E)-tetradecadienamide
(E,E)-N-(2-Methylpropyl)-2,4-tetradecadienamide
N-isobutyl-(2E,4E)-2,4-tetradecadienamide
[ Show all ]
Inchi KeyAGJAUFUNZWHLKE-SQIWNDBBSA-N
Inchi IDInChI=1S/C18H33NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-18(20)19-16-17(2)3/h12-15,17H,4-11,16H2,1-3H3,(H,19,20)/b13-12+,15-14+
PubChem CID10731388
ChEMBLCHEMBL2442640
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
Ki22500.0 nMPMID24095014ChEMBL

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