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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Proteinase-activated receptor 4
Species	Homo sapiens (Human)
Gene	F2RL3
Synonym	protease-activated receptor 4 PAR4 PAR-4 F2R like thrombin/trypsin receptor 3 coagulation factor II receptor-like 3 coagulation factor II (thrombin) receptor-like 3 Thrombin receptor-like 3 [ Show all ]
Disease	N/A
Length	385
Amino acid sequence	MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ
UniProt	Q96RI0
Protein Data Bank	N/A
GPCR-HGmod model	Q96RI0
3D structure model	This predicted structure model is from GPCR-EXP Q96RI0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4691
IUPHAR	350
DrugBank	N/A

Ligand

Name	CHEMBL3732045
Molecular formula	C27H21N3O5S
IUPAC name	2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)-4-[(3-phenylmethoxyphenyl)methoxy]-1-benzofuran-6-ol
Molecular weight	499.541
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.8
Synonyms	4-((3-(Benzyloxy)benzyl)oxy)-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-6-ol BQMUKADQEJFADT-UHFFFAOYSA-N SCHEMBL15359262
Inchi Key	BQMUKADQEJFADT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H21N3O5S/c1-32-27-29-30-14-22(28-26(30)36-27)25-13-21-23(11-19(31)12-24(21)35-25)34-16-18-8-5-9-20(10-18)33-15-17-6-3-2-4-7-17/h2-14,31H,15-16H2,1H3
PubChem CID	72202432
ChEMBL	CHEMBL3732045
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	7.79 nM	None	ChEMBL

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