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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Somatostatin receptor type 4
Species	Homo sapiens (Human)
Gene	SSTR4
Synonym	SS4R SS4-R SS-4-R SRIF2B SST4 receptor
Disease	N/A
Length	388
Amino acid sequence	MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
UniProt	P31391
Protein Data Bank	N/A
GPCR-HGmod model	P31391
3D structure model	This predicted structure model is from GPCR-EXP P31391.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1853
IUPHAR	358
DrugBank	BE0009273

Ligand

Name	CHEMBL3780496
Molecular formula	C24H24ClNO2
IUPAC name	8-(3-aminopropyl)-6-chloro-2-(2-naphthalen-1-ylethyl)-2,3-dihydrochromen-4-one
Molecular weight	393.911
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50155309
Inchi Key	CDZZBXHFECBHBX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24ClNO2/c25-19-13-18(8-4-12-26)24-22(14-19)23(27)15-20(28-24)11-10-17-7-3-6-16-5-1-2-9-21(16)17/h1-3,5-7,9,13-14,20H,4,8,10-12,15,26H2
PubChem CID	127032865
ChEMBL	CHEMBL3780496
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	7090.0 nM	PMID26974375	ChEMBL

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