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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Trace amine-associated receptor 1
Species	Mus musculus (Mouse)
Gene	Taar1
Synonym	TA1 receptor TaR-1 TAR1 trace amine receptor 1 TRAR1
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
UniProt	Q923Y8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4908
IUPHAR	364
DrugBank	N/A

Ligand

Name	SCHEMBL1991690
Molecular formula	C16H16ClN3O
IUPAC name	4-chloro-N-(6-pyrrolidin-3-ylpyridin-3-yl)benzamide
Molecular weight	301.774
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.1
Synonyms	ABRIYQXZDGDZAN-UHFFFAOYSA-N 1312561-45-7 US9452980, 140 BDBM250230 CHEMBL3912684 Benzamide, 4-chloro-N-[6-(3-pyrrolidinyl)-3-pyridinyl]- (RS)-4-chloro-N-(6-pyrrolidin-3-yl-pyridin-3-yl)-benzamide [ Show all ]
Inchi Key	ABRIYQXZDGDZAN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H16ClN3O/c17-13-3-1-11(2-4-13)16(21)20-14-5-6-15(19-10-14)12-7-8-18-9-12/h1-6,10,12,18H,7-9H2,(H,20,21)
PubChem CID	67239828
ChEMBL	CHEMBL3912684
IUPHAR	N/A
BindingDB	250230
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	245.2 nM	, None	BindingDB,ChEMBL

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