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Name | Apelin receptor |
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Species | Homo sapiens (Human) |
Gene | APLNR |
Synonym | msr/apj GPCR34 G-protein coupled receptor HG11 G-protein coupled receptor APJ AGTRL1 [ Show all ] |
Disease | N/A |
Length | 380 |
Amino acid sequence | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQETLVVD |
UniProt | P35414 |
Protein Data Bank | 5vbl |
GPCR-HGmod model | P35414 |
3D structure model | This structure is from PDB ID 5vbl. |
BioLiP | BL0380094, BL0380093 |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1628481 |
IUPHAR | 36 |
DrugBank | N/A |
Name | MLS000772464 |
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Molecular formula | C13H7F2N3OS |
IUPAC name | N-(4,6-difluoro-1,3-benzothiazol-2-yl)pyridine-2-carboxamide |
Molecular weight | 291.276 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | 3.0 |
Synonyms | AKOS032603388 KUC108601N SCHEMBL16919783 CHEMBL1505604 N-(4,6-difluoro-1,3-benzothiazol-2-yl)-2-pyridinecarboxamide [ Show all ] |
Inchi Key | DGGAJGHSEZTQRX-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C13H7F2N3OS/c14-7-5-8(15)11-10(6-7)20-13(17-11)18-12(19)9-3-1-2-4-16-9/h1-6H,(H,17,18,19) |
PubChem CID | 2474590 |
ChEMBL | CHEMBL1505604 |
IUPHAR | N/A |
BindingDB | 60259 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 5880.0 nM | N/A | BindingDB |
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