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Name | 5-hydroxytryptamine receptor 1F |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Htr1f |
Synonym | HTR1EL 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 5-HT6 5-HT1F receptor 5-HT1F [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 366 |
Amino acid sequence | MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINCLVITAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQGLCDLWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGITITTVWVISVFISVPPLFWRHQGNSRDDQCIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVLLESGEKSIKLVSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNICEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRN |
UniProt | P30940 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4646 |
IUPHAR | 5 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
26576 | Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
124413 | CHEMBL104985 | C14H18ClN3O | 279.768 | 4 / 0 | 3.4 | Yes |
174893 | methysergide | C21H27N3O2 | 353.466 | 3 / 2 | 2.3 | Yes |
175666 | sumatriptan | C14H21N3O2S | 295.401 | 4 / 2 | 0.9 | Yes |
244526 | A-131701 | C24H24N4O3S | 448.541 | 6 / 1 | 3.2 | Yes |
290323 | serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
299045 | methiothepin | C20H24N2S2 | 356.546 | 4 / 0 | 4.2 | Yes |
375971 | 5-Carboxamidotryptamine | C11H13N3O | 203.245 | 2 / 3 | -0.6 | Yes |
386150 | metergoline | C25H29N3O2 | 403.526 | 3 / 1 | 3.8 | Yes |
388286 | ERGOTAMINE | C33H35N5O5 | 581.673 | 6 / 3 | 2.0 | No |
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