You can:
| Name | 5-hydroxytryptamine receptor 5A |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Htr5a |
| Synonym | MR22 Htr5 5HT5- 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 5-HT5alpha [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 357 |
| Amino acid sequence | MDLPVNLTSFSLSTPSSLEPNRSLDTEVLRPSRPFLSAFRVLVLTLLGFLAAATFTWNLLVLATILKVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRTRKRVSNVMILLTWALSTVISLAPLLFGWGETYSEPSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYRAAKFRMGSRKTNSVSPVPEAVEVKNATQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDVPAIWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ |
| UniProt | P30966 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3597 |
| IUPHAR | 10 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 11715 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12459 |  CHEMBL338696 | C22H25FN2O | 352.453 | 3 / 1 | 3.6 | Yes |
| 13667 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 14105 |  CHEMBL126724 | C20H21FN2O | 324.399 | 3 / 1 | 4.1 | Yes |
| 20404 |  CHEMBL338095 | C21H22ClFN2O | 372.868 | 3 / 0 | 4.7 | Yes |
| 21855 |  CHEMBL126737 | C21H22ClFN2O | 372.868 | 3 / 0 | 4.7 | Yes |
| 26577 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 30832 |  CHEMBL129230 | C22H23FN2O | 350.437 | 3 / 0 | 3.7 | Yes |
| 39053 |  CHEMBL126823 | C21H24N2O | 320.436 | 2 / 0 | 3.9 | Yes |
| 40966 |  16502-01-5 | C11H12N2 | 172.231 | 1 / 2 | 1.5 | Yes |
| 62218 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 83874 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 112555 |  CHEMBL338081 | C22H26N2O | 334.463 | 2 / 0 | 3.6 | Yes |
| 117099 |  CHEMBL128184 | C22H25FN2O2 | 368.452 | 4 / 0 | 4.0 | Yes |
| 131935 |  CHEMBL129472 | C22H26N2 | 318.464 | 1 / 0 | 4.6 | Yes |
| 134528 |  CHEMBL126188 | C25H26N2O | 370.496 | 2 / 0 | 5.2 | No |
| 143842 |  CHEMBL126438 | C20H22N2O | 306.409 | 2 / 1 | 4.0 | Yes |
| 146035 |  CHEMBL96504 | C21H23FN2O | 338.426 | 3 / 0 | 4.0 | Yes |
| 150832 |  CHEMBL338091 | C21H21FN2O | 336.41 | 3 / 1 | 3.7 | Yes |
| 554083 |  ritanserin | C27H25F2N3OS | 477.574 | 6 / 0 | 5.2 | No |
| 163959 |  pindolol | C14H20N2O2 | 248.326 | 3 / 3 | 1.8 | Yes |
| 167663 |  CHEMBL424258 | C20H22N2O | 306.409 | 2 / 1 | 4.0 | Yes |
| 171172 |  15532-75-9 | C11H13F3N2 | 230.234 | 5 / 1 | 2.3 | Yes |
| 174865 |  methysergide | C21H27N3O2 | 353.466 | 3 / 2 | 2.3 | Yes |
| 175660 |  sumatriptan | C14H21N3O2S | 295.401 | 4 / 2 | 0.9 | Yes |
| 176690 |  RU 24969 | C14H16N2O | 228.295 | 2 / 2 | 1.8 | Yes |
| 184671 |  CHEMBL340511 | C25H26N2O | 370.496 | 2 / 0 | 5.2 | No |
| 195197 |  CHEMBL92879 | C12H14N2 | 186.258 | 1 / 1 | 1.4 | Yes |
| 208302 |  CHEMBL97518 | C22H29N3O2 | 367.493 | 3 / 3 | 2.9 | Yes |
| 239074 |  CHEMBL125361 | C24H30N2 | 346.518 | 1 / 0 | 5.7 | No |
| 250672 |  CHEMBL125417 | C23H28N2 | 332.491 | 1 / 0 | 5.1 | No |
| 270075 |  CHEMBL129476 | C22H24N2O | 332.447 | 2 / 0 | 3.6 | Yes |
| 271521 |  CHEMBL126574 | C21H24N2 | 304.437 | 1 / 0 | 4.2 | Yes |
| 290292 |  serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
| 566372 |  clozapine | C18H19ClN4 | 326.828 | 3 / 1 | 3.1 | Yes |
| 294505 |  CHEMBL126021 | C15H20N2O | 244.338 | 2 / 1 | 1.6 | Yes |
| 299041 |  methiothepin | C20H24N2S2 | 356.546 | 4 / 0 | 4.2 | Yes |
| 313012 |  dl-Arterenol | C8H11NO3 | 169.18 | 4 / 4 | -1.2 | Yes |
| 316150 |  CHEMBL129163 | C21H22N2O | 318.42 | 2 / 1 | 3.6 | Yes |
| 319887 |  CHEMBL128099 | C22H26N2O | 334.463 | 2 / 0 | 4.2 | Yes |
| 323292 |  CHEMBL129774 | C23H24N2 | 328.459 | 1 / 0 | 4.4 | Yes |
| 326926 |  CHEMBL128945 | C23H28N2O | 348.49 | 2 / 0 | 4.5 | Yes |
| 331235 |  CHEMBL2111848 | C23H26N2 | 330.475 | 1 / 0 | 4.6 | Yes |
| 331236 |  CHEMBL446356 | C23H26N2 | 330.475 | 1 / 0 | 4.6 | Yes |
| 337094 |  CHEMBL128848 | C21H24N2O | 320.436 | 2 / 0 | 3.9 | Yes |
| 341840 |  1011-17-2 | C10H14N2O | 178.235 | 3 / 2 | 1.0 | Yes |
| 355124 |  1-(3-Chlorophenyl)piperazine | C10H13ClN2 | 196.678 | 2 / 1 | 1.7 | Yes |
| 357411 |  2-Bromolysergic acid diethylamide | C20H24BrN3O | 402.336 | 2 / 1 | 4.0 | Yes |
| 359491 |  1-(1-Naphthyl)piperazine | C14H16N2 | 212.296 | 2 / 1 | 2.6 | Yes |
| 364106 |  Bufotenine | C12H16N2O | 204.273 | 2 / 2 | 1.2 | Yes |
| 367172 |  dopamine | C8H11NO2 | 153.181 | 3 / 3 | -1.0 | Yes |
| 375952 |  5-Carboxamidotryptamine | C11H13N3O | 203.245 | 2 / 3 | -0.6 | Yes |
| 385800 |  2-Methyl-5-hydroxytryptamine | C11H14N2O | 190.246 | 2 / 3 | 1.4 | Yes |
| 386748 |  CHEMBL341506 | C22H25FN2 | 336.454 | 2 / 0 | 4.7 | Yes |
| 388277 |  ERGOTAMINE | C33H35N5O5 | 581.673 | 6 / 3 | 2.0 | No |
| 399375 |  quipazine | C13H15N3 | 213.284 | 3 / 1 | 1.5 | Yes |
| 415602 |  CHEMBL130586 | C27H28N2O | 396.534 | 2 / 0 | 5.5 | No |
| 555391 |  D-Lysergic acid | C16H16N2O2 | 268.316 | 3 / 2 | 0.0 | Yes |
| 423608 |  D-Lysergic acid | C16H16N2O2 | 268.316 | 3 / 2 | 0.0 | Yes |
| 429677 |  CHEMBL128185 | C22H25FN2O2 | 368.452 | 4 / 0 | 4.0 | Yes |
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