You can:
| Name | Prostaglandin E2 receptor EP2 subtype |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | PTGER2 |
| Synonym | PGE receptor EP2 subtype PGE2 receptor EP2 subtype prostaglandin E receptor 2 (subtype EP2), 53kDa Prostanoid EP2 receptor Ptger-ep2 [ Show all ] |
| Disease | Osteoporosis Pulmonary arterial hypertension Miscarriage Medical abortion Immune disorder [ Show all ] |
| Length | 358 |
| Amino acid sequence | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL |
| UniProt | P43116 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P43116 |
| 3D structure model | This predicted structure model is from GPCR-EXP P43116. |
| BioLiP | N/A |
| Therapeutic Target Database | T38529 |
| ChEMBL | CHEMBL1881 |
| IUPHAR | 341 |
| DrugBank | BE0000368 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 555479 |  SCHEMBL17472597 | C27H27N3O5S2 | 537.649 | 9 / 2 | 4.9 | No |
| 430 |  CHEMBL2164612 | C40H43BF4N2O4 | 702.598 | 10 / 1 | N/A | No |
| 852 |  CHEMBL180742 | C26H22Cl2O4 | 469.358 | 4 / 2 | 6.4 | No |
| 535933 |  CHEMBL3904946 | C24H25FO4 | 396.458 | 5 / 2 | 3.9 | Yes |
| 1595 |  CHEMBL207203 | C23H24ClNO5S | 461.957 | 5 / 2 | 3.0 | Yes |
| 1630 |  CHEMBL3264203 | C22H23FN2O | 350.437 | 2 / 1 | 4.6 | Yes |
| 1821 |  CHEMBL314533 | C38H34N2O4S | 614.76 | 4 / 1 | 7.6 | No |
| 3051 |  CHEMBL3115074 | C23H28N2O4 | 396.487 | 5 / 2 | 1.3 | Yes |
| 3424 |  CHEMBL3264220 | C23H28N2O4 | 396.487 | 4 / 1 | 3.5 | Yes |
| 517335 |  CHEMBL3955120 | C24H24FNO3 | 393.458 | 5 / 2 | 5.8 | No |
| 536047 |  SCHEMBL2012413 | C24H36O4 | 388.548 | 4 / 2 | 5.1 | No |
| 4547 |  CHEMBL430124 | C20H27NO4S | 377.499 | 5 / 2 | 2.4 | Yes |
| 521598 |  CHEMBL3793009 | C20H22ClNO6 | 407.847 | 7 / 2 | 3.2 | Yes |
| 517344 |  CHEMBL3893847 | C28H35F2NO4S | 519.648 | 7 / 2 | 6.8 | No |
| 517346 |  CHEMBL3968443 | C28H35F2NO4S | 519.648 | 7 / 2 | 6.8 | No |
| 536085 |  CHEMBL354419 | C20H18N6O2 | 374.404 | 7 / 1 | 1.8 | Yes |
| 6658 |  CHEMBL313266 | C27H27NO4S4 | 557.756 | 7 / 1 | 6.5 | No |
| 517356 |  CHEMBL1202209 | C21H25FN2 | 324.443 | 3 / 0 | 4.5 | Yes |
| 7183 |  CHEMBL3286709 | C24H30N4O | 390.531 | 3 / 1 | 3.0 | Yes |
| 521661 |  CHEMBL3806076 | C19H20FNO5S | 393.429 | 8 / 2 | 2.9 | Yes |
| 517362 |  CHEMBL3971730 | C21H15F4NO4 | 421.348 | 9 / 3 | 4.6 | Yes |
| 8448 |  CHEMBL417171 | C21H26F3NO4 | 413.437 | 7 / 2 | 3.1 | Yes |
| 536212 |  SCHEMBL5208850 | C21H29ClO3 | 364.91 | 3 / 2 | 5.1 | No |
| 9199 |  CHEMBL123844 | C27H22O3 | 394.47 | 3 / 1 | 5.3 | No |
| 536224 |  SCHEMBL5205658 | C27H39ClO4 | 463.055 | 4 / 2 | 5.5 | No |
| 10346 |  CID 52944193 | C52H48O6 | 768.95 | 6 / 2 | N/A | No |
| 464233 |  CHEMBL3586319 | C26H25NO3S | 431.55 | 5 / 0 | 5.6 | No |
| 11635 |  AH 6809 | C17H14O5 | 298.294 | 5 / 1 | 3.9 | Yes |
| 12369 |  BDBM50370468 | C25H22O4 | 386.447 | 4 / 2 | 5.5 | No |
| 12777 |  CID 53394056 | C22H30O5 | 374.477 | 5 / 3 | 2.1 | Yes |
| 13137 |  CHEMBL275245 | C23H33NO5 | 403.519 | 5 / 2 | 2.2 | Yes |
| 13418 |  CHEMBL3286714 | C19H17FN4O | 336.37 | 3 / 2 | 3.3 | Yes |
| 13565 |  CHEMBL125110 | C26H22O3S | 414.519 | 4 / 1 | 6.1 | No |
| 464549 |  CHEMBL3586353 | C23H19ClN2OS | 406.928 | 4 / 0 | 5.2 | No |
| 13897 |  CHEMBL181035 | C24H20O3 | 356.421 | 3 / 1 | 5.6 | No |
| 555540 |  SCHEMBL17472643 | C29H28N4O4S | 528.627 | 8 / 2 | 4.9 | No |
| 14342 |  CHEMBL251294 | C20H27NO4 | 345.439 | 4 / 2 | 2.8 | Yes |
| 14359 |  CHEMBL3264208 | C22H24N2O3 | 364.445 | 3 / 2 | 4.1 | Yes |
| 442246 |  [(5Z,8R,9S,11R,12R,13E,15S)-9,11,15-Trihydroxy-1-norprosta-5,13-diene-2-yl]phosphinic acid | C19H35O5P | 374.458 | 5 / 4 | 1.9 | Yes |
| 15304 |  CHEMBL180089 | C26H23FO3 | 402.465 | 4 / 1 | 6.4 | No |
| 16333 |  CHEMBL90491 | C37H32N2O4S | 600.733 | 4 / 1 | 7.3 | No |
| 17050 |  CHEMBL87797 | C28H28N2O5S2 | 536.661 | 6 / 2 | 6.0 | No |
| 17939 |  CHEMBL3286635 | C22H27N3O | 349.478 | 2 / 1 | 4.2 | Yes |
| 18201 |  CHEMBL251710 | C20H25NO3 | 327.424 | 3 / 1 | 3.9 | Yes |
| 18631 |  CHEMBL3286645 | C19H19N3O2 | 321.38 | 2 / 2 | 2.2 | Yes |
| 536453 |  SCHEMBL1310801 | C21H25NO5 | 371.433 | 5 / 1 | 3.4 | Yes |
| 557887 |  SCHEMBL18357252 | C30H29ClFNO4 | 522.013 | 5 / 2 | 5.7 | No |
| 536483 |  SCHEMBL2011904 | C24H34O4 | 386.532 | 4 / 2 | 4.4 | Yes |
| 536538 |  SCHEMBL5203473 | C24H37ClO4 | 425.006 | 4 / 2 | 5.4 | No |
| 22149 |  DG-041 | C23H15Cl4FN2O3S2 | 592.302 | 5 / 1 | 7.8 | No |
| 522130 |  CHEMBL3775436 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 522175 |  CHEMBL3775769 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 536548 |  CHEMBL3896035 | C27H36F4N4O5S | 604.662 | 11 / 2 | 5.6 | No |
| 22805 |  CHEMBL601299 | C20H14Cl3NO3S | 454.746 | 4 / 2 | 6.4 | No |
| 23018 |  CHEMBL3286673 | C20H23N3O | 321.424 | 2 / 2 | 2.6 | Yes |
| 23033 |  CHEMBL46395 | C22H30F3NO4 | 429.48 | 7 / 2 | 3.9 | Yes |
| 459421 |  SCHEMBL2194130 | C24H32O5 | 400.515 | 5 / 3 | 3.0 | Yes |
| 553376 |  prostaglandin D2 | C20H32O5 | 352.471 | 5 / 3 | 2.6 | Yes |
| 517454 |  CHEMBL1202203 | C19H23N3 | 293.414 | 3 / 0 | 2.9 | Yes |
| 555574 |  SCHEMBL17472566 | C28H28N4O5S | 532.615 | 9 / 2 | 4.2 | No |
| 465994 |  CHEMBL3586309 | C24H22N2O2S | 402.512 | 5 / 0 | 4.5 | Yes |
| 536645 |  SCHEMBL671511 | C29H38F4N4O5S | 630.7 | 11 / 2 | 6.2 | No |
| 536660 |  SCHEMBL2014800 | C25H32O4S | 428.587 | 5 / 2 | 5.5 | No |
| 536672 |  SCHEMBL1309617 | C21H25NO4S | 387.494 | 5 / 1 | 4.0 | Yes |
| 26661 |  CHEMBL3286718 | C23H25N3O2 | 375.472 | 3 / 2 | 3.5 | Yes |
| 26672 |  MLS000553986 | C22H17ClFN5O5S3 | 582.036 | 11 / 3 | 5.3 | No |
| 536685 |  SCHEMBL2010315 | C24H36O4 | 388.548 | 4 / 2 | 5.1 | No |
| 466238 |  CHEMBL3586326 | C24H22N2O2S | 402.512 | 5 / 0 | 4.6 | Yes |
| 27563 |  CID 52945421 | C50H44O6 | 740.896 | 6 / 2 | N/A | No |
| 466281 |  CHEMBL3586333 | C22H21ClN2O2 | 380.872 | 4 / 0 | 4.2 | Yes |
| 517460 |  CHEMBL3910551 | C22H15F3N2O3 | 412.368 | 8 / 2 | 4.6 | Yes |
| 28271 |  CHEMBL3286669 | C18H19N3O3S | 357.428 | 4 / 2 | 1.9 | Yes |
| 517467 |  CHEMBL3903635 | C23H22FNO4 | 395.43 | 6 / 3 | 5.1 | No |
| 28689 |  CHEMBL45008 | C22H28F3NO4 | 427.464 | 7 / 2 | 3.4 | Yes |
| 522424 |  CHEMBL3793911 | C23H28N2O4 | 396.487 | 5 / 1 | 1.1 | Yes |
| 522430 |  CHEMBL3794185 | C21H23ClO5S | 422.92 | 6 / 2 | 4.4 | Yes |
| 31007 |  CHEMBL208260 | C21H18ClF2NO2 | 389.827 | 4 / 1 | 4.9 | Yes |
| 32543 |  CHEMBL223744 | C22H31NO4 | 373.493 | 4 / 2 | 3.8 | Yes |
| 33558 |  CHEMBL3264209 | C23H24F2N2O4 | 430.452 | 6 / 2 | 4.2 | Yes |
| 34237 |  CHEMBL3286655 | C23H27FN4O | 394.494 | 4 / 1 | 3.3 | Yes |
| 522567 |  CHEMBL3794585 | C20H22ClNO6S | 439.907 | 8 / 2 | 3.4 | Yes |
| 34376 |  CHEMBL434247 | C29H26O3 | 422.524 | 3 / 1 | 7.0 | No |
| 34827 |  UNII-86KF5VSV88 | C27H21F3N2O3 | 478.471 | 6 / 2 | 5.1 | No |
| 38273 |  CHEMBL428524 | C19H35NO4 | 341.492 | 4 / 2 | 3.4 | Yes |
| 38279 |  CHEMBL14286 | C19H35NO4 | 341.492 | 4 / 2 | 3.4 | Yes |
| 38289 |  64054-40-6 | C19H35NO4 | 341.492 | 4 / 2 | 3.4 | Yes |
| 38454 |  CHEMBL314200 | C30H31NO5S2 | 549.7 | 6 / 1 | 7.1 | No |
| 38592 |  CHEMBL425681 | C22H34O6 | 394.508 | 6 / 4 | 3.2 | Yes |
| 39102 |  CHEMBL197319 | C26H25NO5 | 431.488 | 5 / 1 | 5.4 | No |
| 537028 |  SCHEMBL5208834 | C22H31ClO4 | 394.936 | 4 / 3 | 4.0 | Yes |
| 41248 |  CHEMBL258332 | C23H24ClNO4 | 413.898 | 4 / 2 | 3.5 | Yes |
| 41347 |  indomethacin | C19H16ClNO4 | 357.79 | 4 / 1 | 4.3 | Yes |
| 41821 |  CHEMBL3260419 | C19H16O4 | 308.333 | 4 / 1 | 4.3 | Yes |
| 41881 |  CHEMBL173299 | C22H34O5S | 410.569 | 6 / 4 | 3.8 | Yes |
| 558545 |  SCHEMBL18357227 | C28H28ClNO4S | 510.045 | 5 / 2 | 5.4 | No |
| 558557 |  SCHEMBL16092614 | C25H37NO4 | 415.574 | 4 / 2 | 4.2 | Yes |
| 44514 |  CHEMBL599051 | C21H18ClNO3S | 399.889 | 4 / 2 | 4.9 | Yes |
| 517530 |  CHEMBL3964577 | C23H21F2NO3 | 397.422 | 6 / 2 | 5.5 | No |
| 45560 |  CHEMBL3286703 | C23H27N3O | 361.489 | 2 / 2 | 4.7 | Yes |
| 46215 |  SCHEMBL1566198 | C23H18FN3O4 | 419.412 | 5 / 4 | 3.1 | Yes |
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