You can:
| Name | C-X-C chemokine receptor type 4 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | CXCR4 |
| Synonym | LESTR LESTR {ECO:0000303|PubMed:8276799} Stromal cell-derived factor 1 receptor LCR1 LAP-3 [ Show all ] |
| Disease | N/A |
| Length | 352 |
| Amino acid sequence | MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS |
| UniProt | P61073 |
| Protein Data Bank | 3oe9, 3oe8, 3oe6, 3odu |
| GPCR-HGmod model | P61073 |
| 3D structure model | This structure is from PDB ID 3oe9. |
| BioLiP | BL0187218, BL0187262,BL0187263, BL0187259,BL0187260,BL0187261, BL0187197,BL0187198 |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2107 |
| IUPHAR | 71 |
| DrugBank | BE0000919 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 535928 |  CHEMBL3972873 | C27H32N6O | 456.594 | 5 / 2 | 2.2 | Yes |
| 535929 |  CHEMBL3981053 | C27H32N6O | 456.594 | 5 / 2 | 2.2 | Yes |
| 1801 |  CHEMBL536302 | C14H21IN6 | 400.268 | 2 / 5 | N/A | N/A |
| 2038 |  CHEMBL218806 | C37H49N11O6 | 743.87 | 8 / 9 | 0.2 | No |
| 2039 |  CHEMBL374421 | C37H49N11O6 | 743.87 | 8 / 9 | 0.2 | No |
| 547933 |  CHEMBL3933958 | C26H36N8O2S | 524.688 | 5 / 4 | 0.8 | No |
| 547934 |  CHEMBL3897010 | C26H36N8O2S | 524.688 | 5 / 4 | 0.8 | No |
| 3716 |  CHEMBL2031828 | C39H42FN7O2 | 659.81 | 6 / 4 | 4.7 | No |
| 3717 |  CHEMBL2031696 | C39H42FN7O2 | 659.81 | 6 / 4 | 4.7 | No |
| 547943 |  CHEMBL3969980 | C19H17F2N3 | 325.363 | 5 / 2 | 4.1 | Yes |
| 5566 |  CHEMBL2180085 | C37H46F3N9O8 | 801.825 | 13 / 10 | N/A | No |
| 7028 |  CHEMBL1956255 | C36H47N11O5 | 713.844 | 7 / 9 | 0.4 | No |
| 7980 |  CHEMBL460483 | C20H30N2S | 330.534 | 2 / 1 | 5.7 | No |
| 536234 |  CHEMBL3958178 | C24H27N5 | 385.515 | 4 / 2 | 2.3 | Yes |
| 536245 |  CHEMBL3946745 | C27H31N5 | 425.58 | 4 / 2 | 3.7 | Yes |
| 536247 |  CHEMBL3935318 | C28H36N6 | 456.638 | 5 / 2 | 2.5 | Yes |
| 536248 |  CHEMBL3911032 | C28H36N6 | 456.638 | 5 / 2 | 2.5 | Yes |
| 536254 |  CHEMBL3974711 | C31H39N5O2 | 513.686 | 6 / 1 | 4.2 | No |
| 10756 |  CHEMBL1682855 | C20H28N4 | 324.472 | 4 / 1 | 2.1 | Yes |
| 11468 |  SCHEMBL6012808 | C23H35N3O2 | 385.552 | 3 / 1 | 3.7 | Yes |
| 536302 |  CHEMBL3925646 | C34H44N6O2 | 568.766 | 7 / 1 | 4.1 | No |
| 12760 |  CID 56647929 | C98H134N24O22 | 2000.3 | 28 / 23 | -5.8 | No |
| 12804 |  CHEMBL462588 | C23H38N4S2 | 434.705 | 4 / 1 | 5.3 | No |
| 13274 |  Spermidine tris-PheG | C28H37N9 | 499.667 | 3 / 5 | 2.9 | Yes |
| 548029 |  CHEMBL3941019 | C23H27N3 | 345.49 | 3 / 2 | 5.5 | No |
| 14347 |  BDBM50363969 | C77H98N18O14 | 1499.74 | 16 / 16 | 2.1 | No |
| 14571 |  CHEMBL2029608 | C37H48N10O5 | 712.856 | 7 / 9 | 1.2 | No |
| 464763 |  CHEMBL3581265 | C39H51N11O6 | 769.908 | 8 / 9 | 0.7 | No |
| 464766 |  CHEMBL3581273 | C39H51N11O6 | 769.908 | 8 / 9 | 0.7 | No |
| 464768 |  CHEMBL3581264 | C39H51N11O6 | 769.908 | 8 / 9 | 0.7 | No |
| 464769 |  CHEMBL3581271 | C39H51N11O6 | 769.908 | 8 / 9 | 0.7 | No |
| 464772 |  CHEMBL3581272 | C39H51N11O6 | 769.908 | 8 / 9 | 0.7 | No |
| 464773 |  CHEMBL3581270 | C39H51N11O6 | 769.908 | 8 / 9 | 0.7 | No |
| 16719 |  CHEMBL1682990 | C18H26N4 | 298.434 | 4 / 1 | 1.7 | Yes |
| 548089 |  CHEMBL3902257 | C26H36N8O2S | 524.688 | 5 / 4 | 0.7 | No |
| 21342 |  CHEMBL3091682 | C26H38N4 | 406.618 | 4 / 2 | 3.8 | Yes |
| 536519 |  CHEMBL3901600 | C27H33N5 | 427.596 | 4 / 2 | 4.1 | Yes |
| 536520 |  CHEMBL3944558 | C27H33N5 | 427.596 | 4 / 2 | 4.1 | Yes |
| 442543 |  CHEMBL2031832 | C40H42FN7O3 | 687.82 | 6 / 4 | 4.9 | No |
| 22673 |  CHEMBL2031701 | C40H42FN7O3 | 687.82 | 6 / 4 | 4.9 | No |
| 23489 |  CHEMBL3091690 | C29H37N5 | 455.65 | 5 / 1 | 3.3 | Yes |
| 25413 |  CHEMBL1682864 | C22H32N4 | 352.526 | 4 / 1 | 2.9 | Yes |
| 536670 |  CHEMBL3976878 | C31H34N6 | 490.655 | 5 / 2 | 4.2 | Yes |
| 536718 |  CHEMBL3947926 | C31H38N6O2S | 558.745 | 7 / 1 | 1.6 | No |
| 536722 |  CHEMBL434161 | C20H25N3O2S | 371.499 | 5 / 1 | 3.9 | Yes |
| 29267 |  CHEMBL235309 | C24H22N2 | 338.454 | 2 / 2 | 6.1 | No |
| 536739 |  CHEMBL3947569 | C36H37N5O2 | 571.725 | 5 / 0 | 5.7 | No |
| 30010 |  CHEMBL2370126 | C80H135N33O18S2 | 1911.29 | 28 / 30 | -11.2 | No |
| 30111 |  1,4-benzenedimethanamine, 2,3,5,6-tetramethyl- | C12H20N2 | 192.306 | 2 / 2 | 1.1 | Yes |
| 30391 |  CHEMBL2031838 | C41H46FN7O2 | 687.864 | 6 / 4 | 5.7 | No |
| 30392 |  CHEMBL2031821 | C41H46FN7O2 | 687.864 | 6 / 4 | 5.7 | No |
| 30602 |  AC1LA88L | C37H43N5O4 | 621.782 | 5 / 2 | 5.7 | No |
| 536826 |  CHEMBL3897039 | C21H23N3 | 317.436 | 3 / 2 | 4.6 | Yes |
| 32251 |  m-Terephthalanisidide | C22H20N2O4 | 376.412 | 4 / 2 | 3.5 | Yes |
| 466877 |  CHEMBL3581285 | C30H47N11O6 | 657.777 | 8 / 8 | -1.9 | No |
| 33742 |  CHEMBL2370132 | C90H140N32O19S2 | 2038.44 | 28 / 30 | -8.0 | No |
| 548311 |  CHEMBL3923084 | C139H221N45O31S2 | 3082.7 | 43 / 50 | -7.0 | No |
| 36447 |  CHEMBL105659 | C34H40N4O2 | 536.72 | 4 / 0 | 6.7 | No |
| 36525 |  CHEMBL2434978 | C32H36N4O4S | 572.724 | 7 / 1 | 2.1 | No |
| 467452 |  CHEMBL3187346 | C27H35N3O5 | 481.593 | 6 / 2 | 4.0 | Yes |
| 37006 |  CHEMBL2170444 | C26H46N4 | 414.682 | 4 / 2 | 4.0 | Yes |
| 37007 |  CHEMBL2170299 | C26H46N4 | 414.682 | 4 / 2 | 4.0 | Yes |
| 37008 |  CHEMBL2170443 | C26H46N4 | 414.682 | 4 / 2 | 4.0 | Yes |
| 38617 |  CHEMBL2031837 | C40H44FN7O2 | 673.837 | 6 / 4 | 5.2 | No |
| 38618 |  CHEMBL2031820 | C40H44FN7O2 | 673.837 | 6 / 4 | 5.2 | No |
| 39800 |  CHEMBL2031835 | C39H40FN7O3 | 673.793 | 6 / 4 | 4.4 | No |
| 39801 |  CHEMBL2031818 | C39H40FN7O3 | 673.793 | 6 / 4 | 4.4 | No |
| 41254 |  CHEMBL2180078 | C32H38N8O6 | 630.706 | 7 / 8 | 0.8 | No |
| 41781 |  CHEMBL480114 | C27H34N10O2 | 530.637 | 4 / 7 | 0.0 | No |
| 42529 |  CHEMBL2372996 | C89H137N31O20S2 | 2025.39 | 28 / 30 | -8.0 | No |
| 522800 |  CHEMBL3828236 | C29H35N3 | 425.62 | 3 / 0 | 5.0 | Yes |
| 43637 |  CHEMBL2180077 | C38H48F3N11O8 | 843.866 | 13 / 11 | N/A | No |
| 43638 |  CHEMBL2180076 | C38H48F3N11O8 | 843.866 | 13 / 11 | N/A | No |
| 522811 |  CHEMBL3827585 | C24H26F2N2 | 380.483 | 4 / 0 | 4.8 | Yes |
| 548393 |  CHEMBL3914095 | C136H215N43O31S2 | 3012.61 | 43 / 48 | -7.9 | No |
| 443497 |  CHEMBL3357471 | C27H39N7O | 477.657 | 3 / 4 | 2.4 | Yes |
| 46432 |  CHEMBL1682860 | C19H27N5 | 325.46 | 5 / 2 | 1.4 | Yes |
| 47791 |  CHEMBL516480 | C20H28N4S2 | 388.592 | 4 / 1 | 4.0 | Yes |
| 48581 |  CHEMBL1092629 | C21H25N5O | 363.465 | 4 / 2 | 1.4 | Yes |
| 522956 |  CHEMBL3827508 | C15H23N3O2 | 277.368 | 5 / 0 | -0.2 | Yes |
| 48721 |  CHEMBL450815 | C30H40N10O2 | 572.718 | 4 / 7 | 2.0 | No |
| 48722 |  CHEMBL501494 | C30H40N10O2 | 572.718 | 4 / 7 | 2.0 | No |
| 48723 |  CHEMBL450041 | C30H40N10O2 | 572.718 | 4 / 7 | 2.0 | No |
| 48968 |  CHEMBL1802280 | C18H16F2N4 | 326.351 | 6 / 2 | 3.6 | Yes |
| 49070 |  CHEMBL545063 | C30H57BrN6 | 581.732 | 6 / 5 | N/A | No |
| 49332 |  CHEMBL3091692 | C29H41N5O2 | 491.68 | 6 / 1 | 2.1 | Yes |
| 49607 |  CHEMBL1802283 | C18H18N4 | 290.37 | 4 / 2 | 3.5 | Yes |
| 469074 |  CHEMBL3188149 | C27H35N3O6 | 497.592 | 7 / 2 | 3.6 | Yes |
| 50313 |  CHEMBL2370134 | C87H134N30O18S2 | 1952.34 | 27 / 28 | -7.1 | No |
| 50978 |  CHEMBL1088916 | C23H31N5 | 377.536 | 4 / 2 | 3.1 | Yes |
| 537259 |  CHEMBL3957139 | C31H40N6O | 512.702 | 6 / 1 | 2.8 | No |
| 537260 |  CHEMBL3975192 | C31H40N6O | 512.702 | 6 / 1 | 2.8 | No |
| 537265 |  CHEMBL3918137 | C33H31N5O2 | 529.644 | 5 / 0 | 4.3 | No |
| 537275 |  CHEMBL3965697 | C19H17N5O4 | 379.376 | 7 / 2 | 3.5 | Yes |
| 52109 |  NSC 66832 | C10H16Cl2N8 | 319.194 | 4 / 6 | N/A | No |
| 52140 |  AMD 3465 | C24H38N6 | 410.61 | 6 / 4 | 0.8 | Yes |
| 53240 |  PharmaGSID_48521 | C31H49N5O4 | 555.764 | 7 / 0 | 4.1 | No |
| 54309 |  CHEMBL545532 | C28H51ClN4O4 | 543.19 | 8 / 3 | N/A | No |
| 469637 |  CHEMBL3627799 | C26H37N5O2 | 451.615 | 6 / 2 | 2.1 | Yes |
| 54824 |  BDBM50363983 | C103H142N26O24 | 2128.43 | 30 / 23 | -8.0 | No |
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