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Name | G-protein coupled bile acid receptor 1 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Gpbar1 |
Synonym | BG37 Membrane-type receptor for bile acids M-BAR hGPCR19 GPR131 [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 329 |
Amino acid sequence | MMSHNTTELSAIPRGVQELSLVLASLIVIANLLLALGIVLDRHLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNRSHQGYWSCLLLHLAPNFCFLSLLANLLLVHGERYMAVLQPLRPHGSVRLALFLTWISSLLFASLPALGWNHWSPGANCSSQAIFPAPYLYLEVYGLLLPAVGATALLSVRVLATAHHQLREIRRLERAVCRDAPSTLARALTWRQARAQAGATLLFLLCWGPYVATLLLSVLAYERRPPLGPVTLLSLISLGSASAAVVPVAMGLGDQRYTAPWRTAAQRWLQVLRGRPKRANPGPSTAYHSSSQCSTDLDLN |
UniProt | Q80T02 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075223 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
35138 | CHEMBL2331646 | C22H29N5O2 | 395.507 | 5 / 2 | 2.5 | Yes |
132791 | TGR5 Receptor Agonist | C18H14Cl2N2O2 | 361.222 | 3 / 0 | 4.7 | Yes |
380671 | CHEMBL576138 | C19H16Cl2N2O2 | 375.249 | 3 / 0 | 5.1 | No |
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