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| Name | D(1A) dopamine receptor |
|---|---|
| Species | Bos taurus (Bovine) |
| Gene | DRD1 |
| Synonym | Dopamine D1 receptor |
| Disease | N/A for non-human GPCRs |
| Length | 446 |
| Amino acid sequence | MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT |
| UniProt | Q95136 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2967 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 2100 |  CHEMBL558838 | C21H28N6O | 380.496 | 6 / 1 | 2.9 | Yes |
| 4223 |  CHEMBL25984 | C15H23NO | 233.355 | 2 / 0 | 3.8 | Yes |
| 4686 |  Moperone | C22H26FNO2 | 355.453 | 4 / 1 | 3.0 | Yes |
| 4972 |  CHEMBL50188 | C25H36N2O4 | 428.573 | 5 / 0 | 4.2 | Yes |
| 5547 |  CHEMBL50722 | C25H36N2O5 | 444.572 | 6 / 0 | 4.3 | Yes |
| 5915 |  CHEMBL50722 | C27H38N2O9 | 534.606 | 10 / 2 | N/A | No |
| 9146 |  CHEMBL144114 | C16H25N | 231.383 | 1 / 0 | 4.1 | Yes |
| 10529 |  CHEMBL341825 | C16H25N | 231.383 | 1 / 0 | 4.1 | Yes |
| 11195 |  CHEMBL2113718 | C16H18N4 | 266.348 | 3 / 1 | 2.2 | Yes |
| 11723 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 11770 |  CHEMBL554692 | C20H24ClN5 | 369.897 | 4 / 0 | 4.4 | Yes |
| 11811 |  CHEMBL54266 | C23H32N2O4S | 432.579 | 6 / 1 | 4.3 | Yes |
| 13130 |  CHEMBL107529 | C19H21N3O | 307.397 | 3 / 0 | 2.7 | Yes |
| 13619 |  ADTN | C10H13NO2 | 179.219 | 3 / 3 | 1.4 | Yes |
| 13679 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 16792 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 17769 |  CHEMBL160396 | C19H21ClN4O | 356.854 | 4 / 1 | 2.2 | Yes |
| 17929 |  CHEMBL492042 | C19H20BrClN4 | 419.751 | 3 / 1 | 4.7 | Yes |
| 20197 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 20617 |  CHEMBL318924 | C14H24N2 | 220.36 | 1 / 0 | 2.9 | Yes |
| 23339 |  Levosulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 23364 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 25087 |  CHEMBL544711 | C14H21N | 203.329 | 1 / 0 | 3.4 | Yes |
| 25513 |  Teflutixol | C23H26F4N2OS | 454.528 | 8 / 1 | 4.6 | Yes |
| 25527 |  UNII-NGJ1K8EOK1 | C21H26N4 | 334.467 | 3 / 1 | 2.9 | Yes |
| 25531 |  CHEMBL352925 | C21H26N4 | 334.467 | 3 / 1 | 2.9 | Yes |
| 26772 |  CHEMBL328925 | C19H21ClN4O | 356.854 | 4 / 1 | 2.2 | Yes |
| 29989 |  CHEMBL561123 | C22H28N6O2 | 408.506 | 5 / 1 | 1.1 | Yes |
| 33032 |  CHEMBL104201 | C20H20N4 | 316.408 | 3 / 0 | 2.7 | Yes |
| 33953 |  Clebopride | C20H24ClN3O2 | 373.881 | 4 / 2 | 3.2 | Yes |
| 38972 |  UNII-F52O5YF6CA | C24H25F4NOS | 451.524 | 7 / 1 | 5.9 | No |
| 38974 |  cis-Piflutixol | C24H25F4NOS | 451.524 | 7 / 1 | 5.9 | No |
| 40516 |  CHEMBL165022 | C17H25N | 243.394 | 1 / 0 | 4.2 | Yes |
| 41059 |  CHEMBL267853 | C17H18ClN5 | 327.816 | 4 / 0 | 3.2 | Yes |
| 42902 |  CHEMBL559868 | C18H19ClN4 | 326.828 | 3 / 1 | 3.4 | Yes |
| 43790 |  CHEMBL483864 | C19H21ClN4 | 340.855 | 3 / 1 | 4.0 | Yes |
| 45898 |  CHEMBL325818 | C24H25BrN2O2 | 453.38 | 3 / 1 | 5.0 | Yes |
| 46016 |  CHEMBL325104 | C18H20N2 | 264.372 | 1 / 0 | 2.9 | Yes |
| 50874 |  CHEMBL520019 | C17H19ClN6 | 342.831 | 5 / 1 | 2.6 | Yes |
| 55358 |  CHEMBL109472 | C31H28N2O2 | 460.577 | 3 / 1 | 6.2 | No |
| 56254 |  CHEMBL294394 | C15H19N3 | 241.338 | 2 / 1 | 2.2 | Yes |
| 56419 |  CHEMBL326454 | C21H26ClN3O2 | 387.908 | 4 / 2 | 3.9 | Yes |
| 56423 |  CHEMBL111749 | C21H26ClN3O2 | 387.908 | 4 / 2 | 3.9 | Yes |
| 56694 |  cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
| 56957 |  CHEMBL544961 | C15H29N | 223.404 | 1 / 0 | 4.9 | Yes |
| 57408 |  CHEMBL298534 | C24H31FN2O3 | 414.521 | 5 / 1 | 4.7 | Yes |
| 62240 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 62319 |  CHEMBL51888 | C22H30N2O4S | 418.552 | 6 / 1 | 3.9 | Yes |
| 62507 |  CHEMBL52438 | C19H25NO | 283.415 | 2 / 0 | 5.1 | No |
| 62702 |  CHEMBL168571 | C21H24N4O | 348.45 | 4 / 1 | 2.3 | Yes |
| 62704 |  CHEMBL168541 | C21H24N4O | 348.45 | 4 / 1 | 2.3 | Yes |
| 63082 |  CHEMBL11592 | C26H38N2O4 | 442.6 | 5 / 0 | 4.6 | Yes |
| 64189 |  CHEMBL550392 | C20H25N5 | 335.455 | 4 / 0 | 3.8 | Yes |
| 64671 |  PD-168077 | C20H22N4O | 334.423 | 4 / 1 | 3.0 | Yes |
| 64763 |  CHEMBL338119 | C16H23N3O2 | 289.379 | 3 / 2 | 2.5 | Yes |
| 65588 |  CHEMBL510055 | C20H23ClN4O | 370.881 | 4 / 1 | 4.0 | Yes |
| 66337 |  CHEMBL483247 | C19H20Cl2N4 | 375.297 | 3 / 1 | 4.6 | Yes |
| 66641 |  CHEMBL131186 | C18H29N3O2 | 319.449 | 3 / 2 | 2.4 | Yes |
| 67226 |  CHEMBL62601 | C27H28BrN3O2 | 506.444 | 5 / 1 | 5.2 | No |
| 67842 |  CHEMBL553258 | C15H23N | 217.356 | 1 / 0 | 3.8 | Yes |
| 68623 |  FAUC 213 | C18H19ClN4 | 326.828 | 3 / 0 | 3.2 | Yes |
| 68931 |  CHEMBL268558 | C22H21ClN4 | 376.888 | 3 / 0 | 4.4 | Yes |
| 68946 |  CHEMBL301060 | C28H40N2O8 | 532.634 | 9 / 2 | N/A | No |
| 70162 |  CHEMBL165171 | C29H33N | 395.59 | 1 / 0 | 7.8 | No |
| 71866 |  1-(1-Benzylpiperidin-4-yl)-1H-pyrrole-2-carbaldehyde | C17H20N2O | 268.36 | 2 / 0 | 2.4 | Yes |
| 73752 |  pramipexole | C10H17N3S | 211.327 | 4 / 2 | 1.9 | Yes |
| 73773 |  ch56 | C19H19N5 | 317.396 | 4 / 1 | 2.2 | Yes |
| 75442 |  CHEMBL550920 | C20H25N5O | 351.454 | 5 / 0 | 3.3 | Yes |
| 75808 |  CHEMBL131120 | C14H22N4 | 246.358 | 3 / 1 | 3.1 | Yes |
| 76091 |  BENPERIDOL | C22H24FN3O2 | 381.451 | 4 / 1 | 3.7 | Yes |
| 76581 |  (R)-zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
| 77555 |  CHEMBL99291 | C15H26N2O | 250.386 | 2 / 1 | 2.1 | Yes |
| 77559 |  CHEMBL95230 | C15H26N2O | 250.386 | 2 / 1 | 2.1 | Yes |
| 77923 |  CHEMBL177031 | C23H28ClN3O | 397.947 | 3 / 1 | 4.0 | Yes |
| 78115 |  CHEMBL164950 | C15H23N3 | 245.37 | 3 / 0 | 2.9 | Yes |
| 78188 |  domperidone | C22H24ClN5O2 | 425.917 | 3 / 2 | 3.9 | Yes |
| 82330 |  CHEMBL293956 | C19H19N5 | 317.396 | 4 / 1 | 2.3 | Yes |
| 82456 |  CHEMBL485499 | C19H21BrN4 | 385.309 | 3 / 1 | 4.1 | Yes |
| 83878 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 84014 |  CHEMBL424575 | C24H32ClN3O2 | 429.989 | 4 / 2 | 5.0 | Yes |
| 84018 |  CHEMBL168274 | C24H32ClN3O2 | 429.989 | 4 / 2 | 5.0 | Yes |
| 84020 |  CHEMBL168611 | C24H32ClN3O2 | 429.989 | 4 / 2 | 5.0 | Yes |
| 84027 |  CHEMBL168544 | C24H32ClN3O2 | 429.989 | 4 / 2 | 5.0 | Yes |
| 87033 |  (A+/-)-Quinpirole dihydrochloride | C13H21N3 | 219.332 | 2 / 1 | 2.3 | Yes |
| 87077 |  QUINPIROLE | C13H21N3 | 219.332 | 2 / 1 | 2.3 | Yes |
| 87856 |  CHEMBL353087 | C22H26ClN3O3 | 415.918 | 4 / 2 | 2.9 | Yes |
| 87863 |  CHEMBL167032 | C22H26ClN3O3 | 415.918 | 4 / 2 | 2.9 | Yes |
| 88080 |  CHEMBL296395 | C22H24N2O4 | 380.444 | 5 / 1 | 2.9 | Yes |
| 88269 |  CHEMBL50993 | C25H36N2O3 | 412.574 | 4 / 0 | 4.6 | Yes |
| 88408 |  CHEMBL156369 | C19H21ClN4 | 340.855 | 3 / 0 | 3.5 | Yes |
| 90083 |  CHEMBL2092872 | C16H26ClN | 267.841 | 1 / 1 | N/A | N/A |
| 90085 |  CHEMBL1788303 | C16H26ClN | 267.841 | 1 / 1 | N/A | N/A |
| 90088 |  3-(3,4-Dimethylphenyl)-1-propyl-piperidine hydrochloride | C16H26ClN | 267.841 | 1 / 1 | N/A | N/A |
| 90507 |  CHEMBL64139 | C23H26BrN3OS | 472.445 | 5 / 1 | 4.6 | Yes |
| 90509 |  CHEMBL2111528 | C23H26BrN3OS | 472.445 | 5 / 1 | 4.6 | Yes |
| 92989 |  CHEMBL300735 | C24H34N2O4S | 446.606 | 6 / 1 | 4.6 | Yes |
| 94511 |  D-Lysergic acid amide | C16H18N3O+ | 268.34 | 1 / 3 | 1.6 | Yes |
| 94904 |  thiothixene | C23H29N3O2S2 | 443.624 | 6 / 0 | 3.8 | Yes |
| 95232 |  CHEMBL354210 | C23H29N3O | 363.505 | 3 / 1 | 3.3 | Yes |
| 97244 |  Cogentinol | C21H25NO | 307.437 | 2 / 0 | 4.5 | Yes |
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