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| Name | P2Y purinoceptor 14 |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | P2ry14 |
| Synonym | G protein-coupled receptor 105 G-protein coupled receptor 105 GPR105 G protein coupled receptor for UDP-glucose P2Y purinoceptor 14 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 338 |
| Amino acid sequence | MNNSTTTDPPNQPCSWNTLITKQIIPVLYGMVFITGLLLNGISGWIFFYVPSSKSFIIYLKNIVVADFLMGLTFPFKVLGDSGLGPWQVNVFVCRVSAVIFYVNMYVSIVFFGLISFDRYYKIVKPLLTSIVQSVNYSKLLSVLVWMLMLLLAVPNIILTNQGVKEVTKIQCMELKNELGRKWHKASNYIFVSIFWVVFLLLIVFYTAITRKIFKSHLKSRKNSTSVKRKSSRNIFSIVLVFVVCFVPYHIARIPYTKSQTEGHYSCRTKETLLYAKEFTLLLSAANVCLDPIIYFFLCQPFREVLNKKLHMSLKVQNDLEVSKTKRENAIHESTDTL |
| UniProt | Q9ESG6 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL1770046 |
| IUPHAR | 330 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 14862 |  CHEMBL1771244 | C28H26FN5O | 467.548 | 5 / 1 | 4.1 | Yes |
| 27412 |  CHEMBL1771241 | C29H27N5O | 461.569 | 4 / 1 | 4.5 | Yes |
| 32451 |  CHEMBL1771450 | C30H27N5O | 473.58 | 4 / 1 | 5.2 | No |
| 36778 |  CHEMBL1774892 | C24H19FO3S | 406.471 | 5 / 1 | 6.3 | No |
| 37556 |  CHEMBL1771449 | C30H27F3N4O | 516.568 | 6 / 1 | 6.3 | No |
| 49418 |  CHEMBL1771248 | C27H24FN5O | 453.521 | 5 / 1 | 4.1 | Yes |
| 63441 |  CHEMBL1771456 | C30H28N4O3 | 492.579 | 5 / 1 | 5.3 | No |
| 78480 |  CHEMBL1774898 | C23H15F3O4S2 | 476.484 | 8 / 1 | 5.8 | No |
| 80591 |  CHEMBL1771454 | C33H30N4O | 498.63 | 3 / 1 | 6.7 | No |
| 97398 |  CHEMBL1771230 | C26H23N5O | 421.504 | 4 / 1 | 3.6 | Yes |
| 98606 |  CHEMBL1774893 | C22H13F3O3S | 414.398 | 7 / 1 | 6.8 | No |
| 101286 |  CHEMBL1771237 | C27H25N5O | 435.531 | 4 / 1 | 3.9 | Yes |
| 101960 |  CHEMBL1771443 | C28H27N5O | 449.558 | 4 / 1 | 4.4 | Yes |
| 104008 |  CHEMBL1771234 | C27H25N5O2 | 451.53 | 5 / 1 | 3.5 | Yes |
| 553818 |  Udp-glucuronic acid | C15H22N2O18P2 | 580.285 | 18 / 9 | -6.4 | No |
| 116074 |  CHEMBL1774887 | C26H22O3 | 382.459 | 3 / 1 | 6.5 | No |
| 553894 |  Udp galactose | C15H24N2O17P2 | 566.302 | 17 / 9 | -6.3 | No |
| 553900 |  UDP-glucose | C15H24N2O17P2 | 566.302 | 17 / 9 | -6.3 | No |
| 127003 |  CHEMBL1771438 | C28H27N5O2 | 465.557 | 5 / 2 | 3.1 | Yes |
| 128371 |  CHEMBL1774885 | C25H18O5 | 398.414 | 5 / 2 | 5.3 | No |
| 139814 |  CHEMBL1771235 | C28H27N5O2 | 465.557 | 5 / 1 | 3.9 | Yes |
| 140477 |  CHEMBL1771441 | C27H23Cl2N5O | 504.415 | 4 / 1 | 5.3 | No |
| 153764 |  CHEMBL1771439 | C29H29N5O | 463.585 | 4 / 1 | 4.7 | Yes |
| 158058 |  CHEMBL1774895 | C22H13F3O4S | 430.397 | 8 / 2 | 7.0 | No |
| 160088 |  CHEMBL1771460 | C28H29N5O2 | 467.573 | 5 / 1 | 4.7 | Yes |
| 173275 |  CHEMBL1771231 | C26H22ClN5O | 455.946 | 4 / 1 | 4.2 | Yes |
| 179980 |  CHEMBL1771238 | C28H27N5O | 449.558 | 4 / 1 | 4.4 | Yes |
| 180606 |  CHEMBL1771251 | C29H29N5O | 463.585 | 4 / 1 | 4.8 | Yes |
| 554208 |  UDP-N-acetylglucosamine | C17H27N3O17P2 | 607.355 | 17 / 9 | -6.6 | No |
| 186741 |  CHEMBL1771249 | C27H24ClN5O | 469.973 | 4 / 1 | 4.6 | Yes |
| 191100 |  CHEMBL1771447 | C30H30N4O | 462.597 | 3 / 1 | 5.8 | No |
| 194352 |  CHEMBL1771246 | C28H26ClN5O | 484.0 | 4 / 1 | 5.0 | Yes |
| 197851 |  CHEMBL1774897 | C23H15F3O5S2 | 492.483 | 9 / 1 | 6.1 | No |
| 203733 |  CHEMBL1774899 | C25H17F3O4S | 470.462 | 7 / 1 | 6.1 | No |
| 212348 |  CHEMBL1771452 | C29H27FN4O | 466.56 | 4 / 1 | 5.5 | No |
| 249215 |  CHEMBL1774886 | C24H16Cl2O3 | 423.289 | 3 / 1 | 7.0 | No |
| 259907 |  CHEMBL1771457 | C29H26N6O | 474.568 | 5 / 1 | 4.1 | Yes |
| 260125 |  CHEMBL1771232 | C26H22ClN5O | 455.946 | 4 / 1 | 4.2 | Yes |
| 262760 |  CHEMBL1774903 | C26H17F5O3 | 472.411 | 8 / 2 | 6.8 | No |
| 269470 |  CHEMBL1771459 | C28H25N7O | 475.556 | 6 / 1 | 3.8 | Yes |
| 273558 |  CHEMBL1774888 | C26H22O3 | 382.459 | 3 / 1 | 6.5 | No |
| 274959 |  CHEMBL1771245 | C28H25F2N5O | 485.539 | 6 / 1 | 4.4 | Yes |
| 277308 |  CHEMBL1774896 | C25H13F9O4S | 580.421 | 14 / 2 | 8.0 | No |
| 279347 |  CHEMBL1771247 | C27H24ClN5O | 469.973 | 4 / 1 | 4.6 | Yes |
| 290378 |  CHEMBL1771445 | C29H28N4O | 448.57 | 3 / 1 | 5.4 | No |
| 290768 |  CHEMBL1771455 | C32H29N5O | 499.618 | 4 / 1 | 5.7 | No |
| 299457 |  CHEMBL1771446 | C30H30N4O | 462.597 | 3 / 1 | 5.8 | No |
| 566963 |  CHEMBL1771437 | C27H25N5O2 | 451.53 | 5 / 2 | 3.7 | Yes |
| 330790 |  CHEMBL1771436 | C28H27N5O2 | 465.557 | 5 / 1 | 4.0 | Yes |
| 332936 |  CHEMBL1774890 | C27H24O4 | 412.485 | 4 / 1 | 6.4 | No |
| 333806 |  CHEMBL1774894 | C22H12F4O3S | 432.389 | 8 / 1 | 6.9 | No |
| 338629 |  CHEMBL1774882 | C24H18O3 | 354.405 | 3 / 1 | 5.8 | No |
| 339552 |  CHEMBL1771451 | C30H27N5O | 473.58 | 4 / 1 | 5.2 | No |
| 339596 |  CHEMBL1771444 | C28H27N5O | 449.558 | 4 / 1 | 4.4 | Yes |
| 339868 |  CHEMBL1771442 | C28H27N5O2 | 465.557 | 4 / 1 | 3.4 | Yes |
| 341501 |  CHEMBL1771242 | C28H25N5O2 | 463.541 | 5 / 1 | 3.3 | Yes |
| 345526 |  CHEMBL1774901 | C26H16F6O3 | 490.401 | 9 / 2 | 7.1 | No |
| 345527 |  CHEMBL1774902 | C26H16F6O3 | 490.401 | 9 / 2 | 7.1 | No |
| 345528 |  CHEMBL1774900 | C26H16F6O3 | 490.401 | 9 / 2 | 7.1 | No |
| 359880 |  CHEMBL1774889 | C20H18O3 | 306.361 | 3 / 1 | 4.9 | Yes |
| 361860 |  CHEMBL1774891 | C24H20O3S | 388.481 | 4 / 1 | 6.2 | No |
| 369212 |  CHEMBL1771458 | C27H26N6O | 450.546 | 5 / 1 | 3.7 | Yes |
| 371040 |  CHEMBL1771250 | C28H26ClN5O | 484.0 | 4 / 1 | 5.0 | Yes |
| 372521 |  CHEMBL1771240 | C28H25N5O | 447.542 | 4 / 1 | 4.3 | Yes |
| 378610 |  CHEMBL1771236 | C27H25N5OS | 467.591 | 5 / 1 | 4.1 | Yes |
| 393750 |  CHEMBL1771239 | C29H29N5O | 463.585 | 4 / 1 | 4.9 | Yes |
| 396410 |  CHEMBL1771453 | C29H27FN4O | 466.56 | 4 / 1 | 5.5 | No |
| 414913 |  CHEMBL1771243 | C28H27N5O2 | 465.557 | 5 / 2 | 3.1 | Yes |
| 420927 |  CHEMBL1771233 | C26H22ClN5O | 455.946 | 4 / 1 | 4.2 | Yes |
| 428041 |  CHEMBL1774884 | C23H16O3 | 340.378 | 3 / 1 | 5.9 | No |
| 429010 |  CHEMBL1771448 | C32H34N4O | 490.651 | 3 / 1 | 6.6 | No |
| 433553 |  CHEMBL1771440 | C28H26ClN5O | 484.0 | 4 / 1 | 5.0 | Yes |
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