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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001164598
Molecular formula	C26H28N4O5
IUPAC name	N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)furan-2-yl]-3-oxoprop-1-en-2-yl]-4-methylbenzamide
Molecular weight	476.533
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.0
Synonyms	AC1M1VW9 MolPort-000-433-360 ST50048244 N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)furan-2-yl]-3-oxidanylidene-prop-1-en-2-yl]-4-methyl-benzamide (2Z)-N-[3-(dimethylamino)propyl]-2-[(4-methylphenyl)carbonylamino]-3-[5-(2-nit rophenyl)(2-furyl)]prop-2-enamide HMS2852K24 N-{1-({[3-(dimethylamino)propyl]amino}carbonyl)-2-[5-(2-nitrophenyl)-2-furyl]vinyl}-4-methylbenzamide AKOS002167761 N-[(Z)-1-[3-(dimethylamino)propylcarbamoyl]-2-[5-(2-nitrophenyl)-2-furyl]vinyl]-4-methyl-benzamide STK794348 CHEMBL1315054 N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)furan-2-yl]-3-oxoprop-1-en-2-yl]-4-methylbenzamide 384369-45-3 SMR000539729 BDBM53105 N-[(Z)-3-[3-(dimethylamino)propylamino]-1-[5-(2-nitrophenyl)-2-furanyl]-3-oxoprop-1-en-2-yl]-4-methylbenzamide ZINC12732673 cid_2131982 N-{(1Z)-3-{[3-(dimethylamino)propyl]amino}-1-[5-(2-nitrophenyl)furan-2-yl]-3-oxoprop-1-en-2-yl}-4-methylbenzamide [ Show all ]
Inchi Key	AAVOXWIZJYSGEP-XLNRJJMWSA-N
Inchi ID	InChI=1S/C26H28N4O5/c1-18-9-11-19(12-10-18)25(31)28-22(26(32)27-15-6-16-29(2)3)17-20-13-14-24(35-20)21-7-4-5-8-23(21)30(33)34/h4-5,7-14,17H,6,15-16H2,1-3H3,(H,27,32)(H,28,31)/b22-17-
PubChem CID	2131982
ChEMBL	CHEMBL1315054
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
572	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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