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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001204131
Molecular formula	C19H11F3N2O2S2
IUPAC name	2-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-2-phenylacetic acid
Molecular weight	420.424
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.0
Synonyms	2-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-2-phenyl-ethanoic acid AKOS000666049 2-[[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)-2-pyridinyl]thio]-2-phenylacetic acid RSC000311 ABUKUMWSIDVZJQ-UHFFFAOYSA-N HMS2835N04 STK539226 2-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-2-phenylacetic acid BAS 06899988 MolPort-000-706-131 2-{[3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl]sulfanyl}-2-phenylacetic acid CHEMBL1895167 SCHEMBL14596752 (3-Cyano-6-thiophen-2-yl-4-trifluoromethyl-pyridin-2-ylsulfanyl)-phenyl-acetic acid AC1MKBWX MCULE-7929962857 {[3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}(phenyl)acetic acid 2-[[3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridyl]thio]-2-phenyl-acetic acid BDBM96481 racemic 2-((3-cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)-pyridin-2-yl)thio)-2-phenylacetic acid 354555-65-0 cid_3154832 SMR000523835 [ Show all ]
Inchi Key	ABUKUMWSIDVZJQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H11F3N2O2S2/c20-19(21,22)13-9-14(15-7-4-8-27-15)24-17(12(13)10-23)28-16(18(25)26)11-5-2-1-3-6-11/h1-9,16H,(H,25,26)
PubChem CID	3154832
ChEMBL	CHEMBL1895167
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1192	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463105	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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