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Ligand

NameCHEMBL188511
Molecular formulaC15H14F3NO5
IUPAC name(1R,2R,3R,5R,6R)-2-amino-3-[(2,4-difluorophenyl)methoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight345.274
Hydrogen bond acceptor9
Hydrogen bond donor3
XlogP-1.7
Synonyms(1R,2R,3R,5R,6R)-2-Amino-3-(2,4-difluoro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
BDBM50151471
Inchi KeyACALBGGRLIEDFO-YUVXLREMSA-N
Inchi IDInChI=1S/C15H14F3NO5/c16-7-2-1-6(9(17)3-7)5-24-10-4-8-11(14(8,18)12(20)21)15(10,19)13(22)23/h1-3,8,10-11H,4-5,19H2,(H,20,21)(H,22,23)/t8-,10-,11+,14-,15+/m1/s1
PubChem CID11290903
ChEMBLCHEMBL188511
IUPHARN/A
BindingDB50151471
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1358Metabotropic glutamate receptor 2P31421Grm2Rattus norvegicus (Rat)872
557342Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872

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