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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1186493
Molecular formula	C23H27ClN4
IUPAC name	N'-[2-[(E)-2-(4-chlorophenyl)ethenyl]-5-methylquinazolin-4-yl]hexane-1,6-diamine
Molecular weight	394.947
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.6
Synonyms	4-aminoquinazoline derivative, 7b N-(6-aminohexyl)-2-[(E)-2-(4-chlorophenyl)ethenyl]-5-methylquinazolin-4-amine BDBM26959
Inchi Key	ACPNQYXVIVYUHR-SDNWHVSQSA-N
Inchi ID	InChI=1S/C23H27ClN4/c1-17-7-6-8-20-22(17)23(26-16-5-3-2-4-15-25)28-21(27-20)14-11-18-9-12-19(24)13-10-18/h6-14H,2-5,15-16,25H2,1H3,(H,26,27,28)/b14-11+
PubChem CID	21100419
ChEMBL	N/A
IUPHAR	N/A
BindingDB	26959
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1767	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
1768	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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