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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	meso-dihydroguaiaretic acid
Molecular formula	C20H26O4
IUPAC name	4-[(2S,3R)-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol
Molecular weight	330.424
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.0
Synonyms	4,4'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol) AC1Q7ADL Guaiacol, 4,4'-(2,3-dimethyltetramethylene)di-, meso- Phenol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis(2-methoxy-, (R,S)- ZINC15052537 4-[(2r,3s)-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol REL-4,4'-((2R,3S)-2,3-dimethyl-1,4-butanediyl)bis(2-methoxyphenol) 66322-34-7 Dihydroguaiaretic acid MLS002473306 SMR001397390 4-[(2r,3s)-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2-methylbutyl]-2-methoxyphenol AKOS028109653 HMS2202B04 Phenol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis[2-methoxy-, (R,S)- 4-[(2S,3R)-4-(4-hydroxy-3-methoxy-phenyl)-2,3-dimethyl-butyl]-2-methoxy-phenol CHEMBL430464 Meso-Dihyroguaiareticacid S81Z40PSJ4 4,4'-dihydroxy-3,3'-dimethoxylignan AC1L9VQV Dihydroguaiaretic acid, meso- Phenol, 4,4'-((2R,3S)-2,3-dimethyl-1,4-butanediyl)bis(2-methoxy-, rel- UNII-S81Z40PSJ4 4-[(2r,3s)-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-met Hoxyphenol CHEBI:68169 meso-1,4-Bis-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutane Phenol,4,4'-(2,3-dimethyl-1,4-butanediyl)bis[2-methoxy- 4-[(2S,3R)-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol CTK4H6503 Mesodihydroguaiaretic Acid SCHEMBL974725 [ Show all ]
Inchi Key	ADFOLUXMYYCTRR-OKILXGFUSA-N
Inchi ID	InChI=1S/C20H26O4/c1-13(9-15-5-7-17(21)19(11-15)23-3)14(2)10-16-6-8-18(22)20(12-16)24-4/h5-8,11-14,21-22H,9-10H2,1-4H3/t13-,14+
PubChem CID	476856
ChEMBL	CHEMBL430464
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2228	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463205	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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