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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Genostrychnine
Molecular formula	C21H22N2O3
IUPAC name	(4aR,5aS,8aS,13aS,15aS,15bR)-6-oxido-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-6-ium-14-one
Molecular weight	350.418
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	1.4
Synonyms	(1S,11S,18S,20R,21R,22S)-12-oxa-8,17-diazaheptacyclo[15.5.2.0(1,18).0(2,7).0(8,22).0(11,21).0(15,20)]tetracosa-2,4,6,14-tetraen-9-one 17-oxide BRN 0102320 N-Oxystrychnine Strychnidin-10-one, 19-oxide Strychnine, N(sup 6)-oxide 7248-28-4 CHEMBL138585 NSC-127569 strychnine N(6)-oxide Strychnine, Nb-oxide AC1Q225V LS-147145 NSC24951 STRYCHNINE SALTS UNII-774C760V46 (4bs,7as,8ar,12as,12br,12cs)-6,7,7a,8,8a,11,12a,12b,12c,13-decahydro-5h,14h-7,9-methano-12-oxa-7,14a-diazacyclohepta[1,2,3-cd]cyclopenta[g]fluoranthen-14-one 7-oxide CHEBI:132703 NSC 127569 Strychnin-N6-oxide Strychnine, N-oxide 774C760V46 EINECS 230-656-5 NSC-24951 Strychnine N-oxide Strychnine-N-oxide ALKALOIDS, N.O.S. MLS000738032 SMR000393707 Strychnine, 19-oxide ZINC4214344 2-27-00-00739 (Beilstein Handbook Reference) NSC 24951 strychnine 19-oxide Strychnine, N6-oxide AC1L2JS1 NSC127569 Strychnine N6-oxide Strychnine_N_Oxide [ Show all ]
Inchi Key	ADTDBAKUQAKBGZ-VXJIXCKJSA-N
Inchi ID	InChI=1S/C21H22N2O3/c24-18-10-16-19-13-9-17-21(6-7-23(17,25)11-12(13)5-8-26-16)14-3-1-2-4-15(14)22(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+,23?/m0/s1
PubChem CID	73393
ChEMBL	CHEMBL138585
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3063	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
3065	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
3064	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
3062	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479

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