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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Oprea1_600257
Molecular formula	C18H20N4O3S2
IUPAC name	2-(6,7-dimethoxy-3-methylquinolin-2-yl)sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
Molecular weight	404.503
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	3.9
Synonyms	SR-01000339491 HMS3361C15 AKOS000698659 Oprea1_645725 CHEMBL1703845 SR-01000339491-1 MLS000692939 ASN 04371040 SMR000285656 HMS2636H03 ZINC928254 [ Show all ]
Inchi Key	ADYCPFWQGVQJBG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20N4O3S2/c1-5-16-21-22-18(27-16)20-15(23)9-26-17-10(2)6-11-7-13(24-3)14(25-4)8-12(11)19-17/h6-8H,5,9H2,1-4H3,(H,20,22,23)
PubChem CID	1171910
ChEMBL	CHEMBL1703845
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3214	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463271	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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