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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000107691
Molecular formula	C22H17FN4O3
IUPAC name	5-[(3-fluorobenzoyl)amino]-N-(furan-2-ylmethyl)-1-phenylpyrazole-4-carboxamide
Molecular weight	404.401
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.6
Synonyms	CBKinase1_001518 MLS000111771 5-[(3-fluorobenzoyl)amino]-N-(furan-2-ylmethyl)-1-phenylpyrazole-4-carboxamide CCG-14815 Oprea1_162525 BIM-0016070.P001 HMS2417C14 CBKinase1_013918 MLS002540490 AC1LLJ7B BRD-K10637864-001-01-5 MCULE-5179246556 5-[(3-fluorobenzoyl)amino]-N-(2-furylmethyl)-1-phenyl-1H-pyrazole-4-carboxamide CBMicro_016287 MolPort-002-190-940 AP-064/14765100 CHEMBL1362135 ZINC752785 [ Show all ]
Inchi Key	AEJPPJWLDYNVNO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H17FN4O3/c23-16-7-4-6-15(12-16)21(28)26-20-19(22(29)24-13-18-10-5-11-30-18)14-25-27(20)17-8-2-1-3-9-17/h1-12,14H,13H2,(H,24,29)(H,26,28)
PubChem CID	1068291
ChEMBL	CHEMBL1362135
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3541	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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