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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL277167
Molecular formula	C23H28N2O7S
IUPAC name	(Z)-6-[(2S,4S,5R)-2-[2-(4-methyl-2-nitrophenoxy)propan-2-yl]-4-(1,3-thiazol-5-yl)-1,3-dioxan-5-yl]hex-4-enoic acid
Molecular weight	476.544
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50280074 (Z)-6-{(2S,4S,5R)-2-[1-Methyl-1-(4-methyl-2-nitro-phenoxy)-ethyl]-4-thiazol-5-yl-[1,3]dioxan-5-yl}-hex-4-enoic acid
Inchi Key	AEMOPCLSCUUOFI-IVWCHCLBSA-N
Inchi ID	InChI=1S/C23H28N2O7S/c1-15-9-10-18(17(11-15)25(28)29)32-23(2,3)22-30-13-16(7-5-4-6-8-20(26)27)21(31-22)19-12-24-14-33-19/h4-5,9-12,14,16,21-22H,6-8,13H2,1-3H3,(H,26,27)/b5-4-/t16-,21+,22+/m1/s1
PubChem CID	9869582
ChEMBL	CHEMBL277167
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3642	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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