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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1514877
Molecular formula	C19H17F3N4O3S2
IUPAC name	2-(2,1,3-benzothiadiazol-4-ylsulfonyl)-1-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone
Molecular weight	470.485
Hydrogen bond acceptor	10
Hydrogen bond donor	0
XlogP	3.0
Synonyms	HMS1900I03 4-[(2-oxo-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)sulfonyl]-2,1,3-benzothiadiazole NCGC00135074-01 MCULE-6287619581 AKOS002070857 ZINC8600682 G845-0079 MolPort-007-887-312 [ Show all ]
Inchi Key	AFHXRHPOGDFLEA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17F3N4O3S2/c20-19(21,22)13-3-1-4-14(11-13)25-7-9-26(10-8-25)17(27)12-31(28,29)16-6-2-5-15-18(16)24-30-23-15/h1-6,11H,7-10,12H2
PubChem CID	16031491
ChEMBL	CHEMBL1514877
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4166	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463393	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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