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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1,3-dimethyl-6-[(3-methylbutyl)amino]pyrimidine-2,4(1H,3H)-dione
Molecular formula	C11H19N3O2
IUPAC name	1,3-dimethyl-6-(3-methylbutylamino)pyrimidine-2,4-dione
Molecular weight	225.292
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.3
Synonyms	AKOS000715300 HMS2166H08 ST50240298 1,3-dimethyl-6-[(3-methylbutyl)amino]-1,3-dihydropyrimidine-2,4-dione MLS000108211 6-(isopentylamino)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione EU-0071400 Oprea1_265514 1,3-Dimethyl-6-(3-methyl-butylamino)-1H-pyrimidine-2,4-dione BAS 00792899 HMS3323F18 STK177260 CHEMBL1362431 MolPort-001-946-849 AC1LFFIM HMS1370A12 SMR000104172 1,3-dimethyl-6-(3-methylbutylamino)pyrimidine-2,4-dione CCG-106510 MCULE-1621738506 ZINC267677 5770-47-8 ChemDiv2_000364 Oprea1_244948 [ Show all ]
Inchi Key	AFRSVCWIBCSISD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H19N3O2/c1-8(2)5-6-12-9-7-10(15)14(4)11(16)13(9)3/h7-8,12H,5-6H2,1-4H3
PubChem CID	777240
ChEMBL	CHEMBL1362431
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4419	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
4420	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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