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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1554845
Molecular formula	C16H17ClN4O3
IUPAC name	methyl 4-chloro-2-[(2-methyl-6,7-dihydro-5H-pyrazolo[1,5-a]pyrimidine-4-carbonyl)amino]benzoate
Molecular weight	348.787
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.8
Synonyms	AKOS001940334 ZINC8598245 E988-0043 methyl 4-chloro-2-{[(2-methyl-6,7-dihydropyrazolo[1,5-a]pyrimidin-4(5H)-yl)carbonyl]amino}benzoate HMS1878P08 NCGC00127404-01 MCULE-1779747345 [ Show all ]
Inchi Key	AFTAEEALTPFSDY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17ClN4O3/c1-10-8-14-20(6-3-7-21(14)19-10)16(23)18-13-9-11(17)4-5-12(13)15(22)24-2/h4-5,8-9H,3,6-7H2,1-2H3,(H,18,23)
PubChem CID	16024370
ChEMBL	CHEMBL1554845
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463430	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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