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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000674515
Molecular formula	C16H20N4O4S2
IUPAC name	ethyl 2-[2-[[2-[(5-ethyl-4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]amino]-1,3-thiazol-5-yl]acetate
Molecular weight	396.48
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	1.9
Synonyms	AC1O441R HMS2654N22 CHEMBL1385045 SMR000313717 ethyl [2-({[(5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}amino)-1,3-thiazol-5-yl]acetate AKOS001747598 MCULE-7483170132 ethyl 2-[2-({2-[(5-ethyl-4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetyl}amino)-1,3-thiazol-5-yl]acetate STK685642 A3745/0158710 ethyl [2-({[(5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]acetyl}amino)-1,3-thiazol-5-yl]acetate ethyl 2-[2-[[2-[(5-ethyl-6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]amino]-1,3-thiazol-5-yl]acetate ZINC18088335 [ Show all ]
Inchi Key	AGHDTIKGIINQCK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H20N4O4S2/c1-4-11-9(3)18-16(20-14(11)23)25-8-12(21)19-15-17-7-10(26-15)6-13(22)24-5-2/h7H,4-6,8H2,1-3H3,(H,17,19,21)(H,18,20,23)
PubChem CID	135472806
ChEMBL	CHEMBL1385045
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4872	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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