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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL144128
Molecular formula	C28H38N6O2
IUPAC name	2-[5-[2-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]ethyl]piperazin-1-yl]ethoxy]-1H-indol-3-yl]ethanamine
Molecular weight	490.652
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	2.3
Synonyms	5,5'-[(Piperazine-1,4-diyl)bis(ethyleneoxy)]bis[1H-indole-3-(ethanamine)] 2-{5-[2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethyl}-piperazin-1-yl)-ethoxy]-1H-indol-3-yl}-ethylamine BDBM50054979
Inchi Key	AIESARVMTCGTRZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H38N6O2/c29-7-5-21-19-31-27-3-1-23(17-25(21)27)35-15-13-33-9-11-34(12-10-33)14-16-36-24-2-4-28-26(18-24)22(6-8-30)20-32-28/h1-4,17-20,31-32H,5-16,29-30H2
PubChem CID	10791244
ChEMBL	CHEMBL144128
IUPHAR	N/A
BindingDB	50054979
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6143	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
6142	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
6141	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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