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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
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Ligand

Name	propranolol
Molecular formula	C16H21NO2
IUPAC name	1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
Molecular weight	259.349
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.0
Synonyms	525P666 Inderal AC1Q1QBV KB-123971 Anapriline KBioGR_001347 b-Propranolol LS-122410 Betachron BRD-A10070317-003-17-6 (1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol CCRIS 3082 1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane D08443 1-(naphthalen-1-yloxy)-3-(propan-2-ylamino)propan-2-ol DTXSID6023525 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)- (9CI) FE-0204 Spectrum5_000751 NSC 91523 (Salt/Mix) PDSP1_001608 Prestwick3_000952 propranololo Reducor SPBio_001658 AB00053537-10 Inderex AKOS016050338 KBio2_005083 Avlocardyl KBioSS_002523 Bedranol Migrastat Bio1_000367 C07407 CHEMBL27 1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol DivK1c_000023 1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol EINECS 235-867-6 2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)- hemangiol Sumial NCGC00015798-08 Obsidan (Salt/Mix) PDSP2_001592 Propanolol Propranolol Hcl Intensol Propranololum [INN-Latin] SBI-0050871.P003 Spectrum2_001699 ICI 45520 (Salt/Mix) AB0108847 Inderol AN-45556 KBio3_001902 AY 64043 L000679 Beta-Tablinen NCGC00015798-05 BPBio1_001040 (+/-)-Propranolol-D7 (ring-D7) solution, 100 mug/mL in methanol with 5% 1 M HCl, ampule of 1 mL, certified reference material CBDivE_006180 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol CTK8I6896 1-(Isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol Dociton 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)- (9CI) Euprovasin 3-[(methylethyl)amino]-1-naphthyloxypropan-2-ol [2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine NCGC00024690-03 PDSP1_000767 Prestwick1_000952 Propanolol,(+/-) PROPRANOLOL,(+) Racemic propranolol Servanolol Spectrum4_000974 Inderal (Salt/Mix) AC1Q1QC0 KBio1_000023 AQHHHDLHHXJYJD-UHFFFAOYSA-N KBioGR_001684 BBL023437 LS-184129 Betadren BSPBio_000944 (A+/-)-Propranolol hydrochloride CHEBI:8499 1-(alpha-naphthoxy)-3-(iso-propylamino)-2-propanol 1-Isopropylamino-3-(1-naphthyloxy)-2-propanol Efektolol 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)- FT-0700657 ST024757 NSC91523 PDSP2_000755 Propanalol Propranolol (INN) Propranololo [DCIT] Reducor line SPBio_003093 HMS2090L21 AB00053537_11 INDERIDE-40/25 ALBB-023324 KBio2_007651 Avlocardyl (Salt/Mix) Kemi S Berkolol MolPort-001-794-623 Bio1_000856 C16H21NO2 .beta.-Propranolol cMAP_000071 1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol dl-propranolol 13013-17-7 EN300-40731 T7896 NCGC00015798-09 Obzidan Pranolol Propanolol [INN-Spanish] Propranolol [INN:BAN] Proprasylyt SCHEMBL12264958 Spectrum3_000883 IDI1_000023 AC1L1JA4 Intermigran Anaprilin KBio3_002993 AY-20694 Lopac0_000896 Beta-Timelets NCGC00015798-06 BRD-A10070317-003-06-9 (.+/-.)-Propranolol CCG-103643 1-((1-Methylethyl)amino)-3-(1-naphthyloxy)-2-propanol D,L-Propranolol 1-(isopropylamino)-3-naphthalen-1-yloxy-propan-2-ol Dociton (Salt/Mix) 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)- F0001-3681 525-66-6 Spectrum4_001222 NINDS_000023 PDSP1_001607 Prestwick2_000952 Propranalol PROPRANOLOL,(-) racemic-Propranolol SPBio_001361 AB00053537 Inderal hydrochloride AKOS000588816 KBio2_002515 ARONIS27011 KBioGR_002515 BDBM25761 MCULE-7804628650 Betalong BSPBio_002682 (S)-(-)-PROPRANOLOL 1-(alpha-naphthoxy)-3-(isopropylamino)-2-propanol DB00571 1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol EINECS 208-378-0 2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, (+-)- GTPL564 STK735510 NCGC00015798-07 Obsidan PDSP2_001591 Propanix Propranolol (TN) Propranololum Sawatal Spectrum2_001301 HMS3428G03 AB00053537_12 INDERIDE-80/25 AN-18866 KBio3_001766 AY 20694 KS-00002WT3 beta-Propranolol NCGC00015798-04 Bio1_001345 (+-)-Propranolol Caridolol 1(-alpha-naphthoxy)-3-(iso-propylamino)-2-propanol Corpendol 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol DL-Propranolol hydrochloride 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)- etalong 3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol W-109550 NCGC00024690-02 Oprea1_304193 Prestwick0_000952 PROPANOLOL(-) PROPRANOLOL, d R,S-Propranolol Hydrochloride SCHEMBL3955 Spectrum3_001071 [ Show all ]
Inchi Key	AQHHHDLHHXJYJD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
PubChem CID	4946
ChEMBL	CHEMBL27
IUPHAR	564
BindingDB	25761
DrugBank	DB00571
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11724	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
11736	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
11717	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
11738	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
11744	5-hydroxytryptamine receptor 1B	O08892	HTR1B	Cavia porcellus (Guinea pig)	389
11725	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
11734	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
11721	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
11732	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
555525	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
11729	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
11714	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
11731	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
11715	5-hydroxytryptamine receptor 5A	P30966	Htr5a	Mus musculus (Mouse)	357
11743	5-hydroxytryptamine receptor 5B	P31387	Htr5b	Mus musculus (Mouse)	370
11727	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
11745	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
521775	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
555524	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
521776	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412