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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL492375
Molecular formula	C25H26N4O3S
IUPAC name	1-methylsulfonyl-N-(3-pyridin-4-ylphenyl)spiro[2H-indole-3,4'-piperidine]-1'-carboxamide
Molecular weight	462.568
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.8
Synonyms	1-(methylsulfonyl)-N-(3-(pyridin-4-yl)phenyl)spiro[indoline-3,4''-piperidine]-1''-carboxamide BDBM50258051 1-(Methylsulfonyl)-N-[3-(pyridin-4-yl)phenyl]-1,2-dihydro-1''H-spiro[indole-3,4''-piperidine]-1''-carboxamide
Inchi Key	BBAUNXQABIGIPM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N4O3S/c1-33(31,32)29-18-25(22-7-2-3-8-23(22)29)11-15-28(16-12-25)24(30)27-21-6-4-5-20(17-21)19-9-13-26-14-10-19/h2-10,13-14,17H,11-12,15-16,18H2,1H3,(H,27,30)
PubChem CID	44573614
ChEMBL	CHEMBL492375
IUPHAR	N/A
BindingDB	50258051
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19347	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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