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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL297224
Molecular formula	C25H33N5O2
IUPAC name	11-[2-[2-(diethylaminomethyl)piperidin-1-yl]acetyl]-8-methyl-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Molecular weight	435.572
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.3
Synonyms	11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]5,11-dihydro-8-methyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one BBXUFVFKSJHXJC-UHFFFAOYSA-N BDBM50018292 11-[2-(2-Diethylaminomethyl-piperidin-1-yl)-acetyl]-8-methyl-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one SCHEMBL10391173 8-Methyl-11-[[2-[(diethylamino)methyl]piperidin-1-yl]acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6(11H)-one [ Show all ]
Inchi Key	BBXUFVFKSJHXJC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H33N5O2/c1-4-28(5-2)16-19-9-6-7-14-29(19)17-23(31)30-22-12-11-18(3)15-20(22)25(32)27-21-10-8-13-26-24(21)30/h8,10-13,15,19H,4-7,9,14,16-17H2,1-3H3,(H,27,32)
PubChem CID	10094518
ChEMBL	CHEMBL297224
IUPHAR	N/A
BindingDB	50018292
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19929	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
19930	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589

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