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Ligand

NameAQ-RA 741
Molecular formulaC27H37N5O2
IUPAC name11-[2-[4-[4-(diethylamino)butyl]piperidin-1-yl]acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Molecular weight463.626
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP3.1
Synonyms11-[[4-[4-(DIETHYLAMINO)BUTYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
AJ-45632
BN0714
CTK4B3549
MolPort-003-983-884
[ Show all ]
Inchi KeyBCUGCHZRMKTPMU-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H37N5O2/c1-3-30(4-2)17-8-7-10-21-14-18-31(19-15-21)20-25(33)32-24-13-6-5-11-22(24)27(34)29-23-12-9-16-28-26(23)32/h5-6,9,11-13,16,21H,3-4,7-8,10,14-15,17-20H2,1-2H3,(H,29,34)
PubChem CID129989
ChEMBLCHEMBL43383
IUPHAR8584
BindingDB81900
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
20537Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
20539Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
20540Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466
20541Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466
20544Muscarinic acetylcholine receptor M3P20309CHRM3Homo sapiens (Human)590
20545Muscarinic acetylcholine receptor M3P08483Chrm3Rattus norvegicus (Rat)589
20538Muscarinic acetylcholine receptor M4P08485Chrm4Rattus norvegicus (Rat)478
20543Muscarinic acetylcholine receptor M4P08173CHRM4Homo sapiens (Human)479
20542Muscarinic acetylcholine receptor M5P08912CHRM5Homo sapiens (Human)532

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