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Ligand

NameCHEMBL2179631
Molecular formulaC28H27NO5
IUPAC name3-[3-[(2-cyclopentyl-1-oxo-3H-isoindol-5-yl)oxymethyl]phenyl]-4-methoxybenzoic acid
Molecular weight457.526
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP4.8
SynonymsBDBM50398743
3'-((2-Cyclopentyl-1-oxoisoindolin-5-yloxy)methyl)-6-methoxybiphenyl-3-carboxylic acid
BUZSAAKSFZMGDU-UHFFFAOYSA-N
SCHEMBL787526
Inchi KeyBUZSAAKSFZMGDU-UHFFFAOYSA-N
Inchi IDInChI=1S/C28H27NO5/c1-33-26-12-9-20(28(31)32)15-25(26)19-6-4-5-18(13-19)17-34-23-10-11-24-21(14-23)16-29(27(24)30)22-7-2-3-8-22/h4-6,9-15,22H,2-3,7-8,16-17H2,1H3,(H,31,32)
PubChem CID66799669
ChEMBLCHEMBL2179631
IUPHARN/A
BindingDB50398743
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
33517Metabotropic glutamate receptor 1P23385Grm1Rattus norvegicus (Rat)1199
33519Metabotropic glutamate receptor 2P31421Grm2Rattus norvegicus (Rat)872
558297Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
33521Metabotropic glutamate receptor 4P31423Grm4Rattus norvegicus (Rat)912
33522Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
33520Metabotropic glutamate receptor 6P35349Grm6Rattus norvegicus (Rat)871
33518Metabotropic glutamate receptor 7P35400Grm7Rattus norvegicus (Rat)915
33523Metabotropic glutamate receptor 8P70579Grm8Rattus norvegicus (Rat)908

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