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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL328866
Molecular formula	C23H26ClN3O3
IUPAC name	N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
Molecular weight	427.929
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.2
Synonyms	SCHEMBL6215657 YM-43611 BDBM50052180 N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
Inchi Key	CPVZPPFHQBIJNB-KRWDZBQOSA-N
Inchi ID	InChI=1S/C23H26ClN3O3/c1-30-21-12-20(26-22(28)16-7-8-16)19(24)11-18(21)23(29)25-17-9-10-27(14-17)13-15-5-3-2-4-6-15/h2-6,11-12,16-17H,7-10,13-14H2,1H3,(H,25,29)(H,26,28)/t17-/m0/s1
PubChem CID	9802631
ChEMBL	CHEMBL328866
IUPHAR	N/A
BindingDB	50052180
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47748	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
47741	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
47739	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
47745	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
47743	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
47744	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
47747	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
47742	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
47746	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
47740	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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