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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL561391
Molecular formula	C20H16ClNO2
IUPAC name	(E)-3-(2-chloro-7-methylquinolin-3-yl)-1-(4-methoxyphenyl)prop-2-en-1-one
Molecular weight	337.803
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.3
Synonyms	ST50879089 (2E)-3-(2-chloro-7-methyl(3-quinolyl))-1-(4-methoxyphenyl)prop-2-en-1-one BAS 00308659 3-(2-Chloro-7-methyl-quinolin-3-yl)-1-(4-methoxy-phenyl)-propenone STK387525 AC1NXFMB (2E)-3-(2-chloro-7-methylquinolin-3-yl)-1-(4-methoxyphenyl)prop-2-en-1-one BDBM50296664 MolPort-001-922-642 3-(2-chloro-7-methylquinolin-3-yl)-1-(4-methoxyphenyl)prop-2-en-1-one ZINC4178956 AKOS000639370 (E)-3-(2-chloro-7-methylquinolin-3-yl)-1-(4-methoxyphenyl)prop-2-en-1-one [ Show all ]
Inchi Key	CUUBGNVRGLJXDQ-JXMROGBWSA-N
Inchi ID	InChI=1S/C20H16ClNO2/c1-13-3-4-15-12-16(20(21)22-18(15)11-13)7-10-19(23)14-5-8-17(24-2)9-6-14/h3-12H,1-2H3/b10-7+
PubChem CID	5752613
ChEMBL	CHEMBL561391
IUPHAR	N/A
BindingDB	50296664
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51122	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
51123	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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