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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BAY 36-7620
Molecular formula	C19H18O2
IUPAC name	(3aS,6aS)-5-methylidene-3a-(naphthalen-2-ylmethyl)-1,4,6,6a-tetrahydrocyclopenta[c]furan-3-one
Molecular weight	278.351
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.9
Synonyms	(3aS,6aS)-Hexahydro-5-methylene-6a-(2-naphthalenylmethyl)-1H-cyclopenta[c]furan-1-one CHEMBL254372 UNII-0P934RSF8B 1H-Cyclopenta(C)furan-1-one, hexahydro-5-methylene-6a-(2-naphthalenylmethyl)-, (3aS,6aS)- BAY-367620 HMS3269K21 (3aS,6aS)-5-methylidene-3a-(naphthalen-2-ylmethyl)-1,4,6,6a-tetrahydrocyclopenta[c]furan-3-one AKOS024457135 BRD-K54704028-001-01-3 PDSP2_001303 0P934RSF8B BAY 367620 D0EI9B ZINC3981060 232605-26-4 BAY36-7620 LS-57768 (3as,6as)-6a-naphtalen-2-ylmethyl-5-methyliden-hexahydro-cyclopenta[c]furan-1-on B5309 SCHEMBL186260 BAY-36-7620 GTPL1381 (3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-hexahydrocyclopenta[c]furan-1-one BDBM50212323 MolPort-023-276-458 [ Show all ]
Inchi Key	CVIRWLJKDBYYOG-MJGOQNOKSA-N
Inchi ID	InChI=1S/C19H18O2/c1-13-8-17-12-21-18(20)19(17,10-13)11-14-6-7-15-4-2-3-5-16(15)9-14/h2-7,9,17H,1,8,10-12H2/t17-,19+/m1/s1
PubChem CID	9903757
ChEMBL	CHEMBL254372
IUPHAR	1381
BindingDB	50212323
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
51480	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
553493	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
555668	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
555667	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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