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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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Ligand

NameAprofene
Molecular formulaC21H27NO2
IUPAC name2-(diethylamino)ethyl 2,2-diphenylpropanoate
Molecular weight325.452
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP3.8
SynonymsTox21_111979
.alpha.,.alpha.-Diphenylpropionic acid .beta.-diethylaminoethyl ester
2-(Diethylamino)ethyl 2,2-diphenylpropanoate #
AKOS003658410
Aprofeno
[ Show all ]
Inchi KeyDIDYGLSKVUKRRP-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H27NO2/c1-4-22(5-2)16-17-24-20(23)21(3,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15H,4-5,16-17H2,1-3H3
PubChem CID71128
ChEMBLCHEMBL26505
IUPHARN/A
BindingDB50005685
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
60655Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
60659Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
60653Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466
60657Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466
60654Muscarinic acetylcholine receptor M3P08483Chrm3Rattus norvegicus (Rat)589
60660Muscarinic acetylcholine receptor M3P20309CHRM3Homo sapiens (Human)590
60656Muscarinic acetylcholine receptor M4P08173CHRM4Homo sapiens (Human)479
60658Muscarinic acetylcholine receptor M4P17200CHRM4Gallus gallus (Chicken)490

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