Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL392419
Molecular formula	C11H14NO5P
IUPAC name	2-amino-2-[(1S,2S,3R)-2-phenyl-3-phosphonocyclopropyl]acetic acid
Molecular weight	271.209
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-3.3
Synonyms	BDBM50207813 (2S,1''S,2''R,3''S)-2-(2''-phosphono-3''-phenylcyclopropyl)glycine
Inchi Key	DLDXPEVIBANPLO-URJDPWSZSA-N
Inchi ID	InChI=1S/C11H14NO5P/c12-9(11(13)14)8-7(10(8)18(15,16)17)6-4-2-1-3-5-6/h1-5,7-10H,12H2,(H,13,14)(H2,15,16,17)/t7-,8+,9?,10-/m1/s1
PubChem CID	44429217
ChEMBL	CHEMBL392419
IUPHAR	N/A
BindingDB	50207813
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62852	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
62853	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
62851	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
62855	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
62854	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
62856	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218