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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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Ligand

NameCHEMBL222424
Molecular formulaC27H27F2N3O
IUPAC name1-(1-benzylpiperidin-4-yl)-4,4-bis(4-fluorophenyl)imidazolidin-2-one
Molecular weight447.53
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.6
SynonymsBDBM50208001
3-(1-benzyl-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one
Inchi KeyDLFIQCGXPLUMEB-UHFFFAOYSA-N
Inchi IDInChI=1S/C27H27F2N3O/c28-23-10-6-21(7-11-23)27(22-8-12-24(29)13-9-22)19-32(26(33)30-27)25-14-16-31(17-15-25)18-20-4-2-1-3-5-20/h1-13,25H,14-19H2,(H,30,33)
PubChem CID16125372
ChEMBLCHEMBL222424
IUPHARN/A
BindingDB50208001
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
62893Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466
62891Muscarinic acetylcholine receptor M3P20309CHRM3Homo sapiens (Human)590
62892Muscarinic acetylcholine receptor M3P08483Chrm3Rattus norvegicus (Rat)589

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