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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1926745
Molecular formula	C21H29N3O3
IUPAC name	2-[4-(3,4-dihydro-2H-chromen-2-ylmethylamino)butyl]-6,7,8,8a-tetrahydro-3H-pyrrolo[1,2-a]pyrazine-1,4-dione
Molecular weight	371.481
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.0
Synonyms	BDBM50359419 SCHEMBL14088270 CHEMBL1962804
Inchi Key	DSCQYJWJCPNZPX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H29N3O3/c25-20-15-23(21(26)18-7-5-13-24(18)20)12-4-3-11-22-14-17-10-9-16-6-1-2-8-19(16)27-17/h1-2,6,8,17-18,22H,3-5,7,9-15H2
PubChem CID	56850658
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50359419
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
67468	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
67472	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
67470	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
67473	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
67471	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
67469	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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