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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SNAP-7915
Molecular formula	C25H28F3N3O3
IUPAC name	(4S,5S)-4-(3,4-difluorophenyl)-N-[3-[4-(4-fluorophenyl)piperidin-1-yl]propyl]-5-methyl-2-oxo-1,3-oxazolidine-3-carboxamide
Molecular weight	475.512
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.0
Synonyms	(4S,5S)-4-(3,4-Difluorophenyl)-N-[3-[4-(4-fluorophenyl)-1-piperidinyl]propyl]-5-methyl-2-oxo-3-oxazolidine carboxamide SCHEMBL7658901 BDBM50090647 (4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide D0D8GV 4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide (4S,5S)-4-(3,4-difluorophenyl)-N-(3-(4-(4-fluorophenyl)piperidin-1-yl)propyl)-5-methyl-2-oxooxazolidine-3-carboxamide DTYAFBJXWWLRMA-QMHKHESXSA-N SNAP7915 CHEMBL96467 [ Show all ]
Inchi Key	DTYAFBJXWWLRMA-QMHKHESXSA-N
Inchi ID	InChI=1S/C25H28F3N3O3/c1-16-23(19-5-8-21(27)22(28)15-19)31(25(33)34-16)24(32)29-11-2-12-30-13-9-18(10-14-30)17-3-6-20(26)7-4-17/h3-8,15-16,18,23H,2,9-14H2,1H3,(H,29,32)/t16-,23+/m0/s1
PubChem CID	9830741
ChEMBL	CHEMBL96467
IUPHAR	N/A
BindingDB	50090647
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68781	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
68789	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
68793	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
68791	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
68784	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
68787	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
68786	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
68795	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
68785	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
68788	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
68790	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
68782	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
68792	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
68783	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
68794	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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