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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(R)-zacopride
Molecular formula	C15H20ClN3O2
IUPAC name	4-amino-N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-5-chloro-2-methoxybenzamide
Molecular weight	309.794
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.7
Synonyms	38126EQF7A CHEMBL27846 UNII-9GN3OT4156 component FEROPKNOYKURCJ-ZDUSSCGKSA-N 4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxy-benzamide PDSP1_001700 ZINC848 (R)ZACOPRIDE BDBM50031475 SCHEMBL5387843 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((R)-methoxy)-benzamide D0AJ3C Zacopride, (R)- (R)-(+)-Zacopride 4-amino-N-[(8R)-1-azabicyclo[2.2.2]octan-8-yl]-5-chloro-2-methoxybenzamide PDSP2_001683 123441-85-0 UNII-38126EQF7A 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide GTPL2288 ZACOPRIDE,S r-zacopride [ Show all ]
Inchi Key	FEROPKNOYKURCJ-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m0/s1
PubChem CID	9819593
ChEMBL	CHEMBL27846
IUPHAR	N/A
BindingDB	50031475
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
76588	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
76584	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
76582	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
76586	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
76589	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
76590	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
76581	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
76587	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
76583	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
76585	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

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