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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL571537
Molecular formula	C33H42N4O5S2
IUPAC name	N-[(4R)-4-[7-(4-cyclobutylpiperazin-1-yl)-3-oxo-1H-isoindol-2-yl]-4-(3,4-dimethoxyphenyl)butyl]-N-methylthiophene-2-sulfonamide
Molecular weight	638.842
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50302266 SCHEMBL2343959 (R)-N-(4-(4-(4-cyclobutylpiperazin-1-yl)-1-oxoisoindolin-2-yl)-4-(3,4-dimethoxyphenyl)butyl)-N-methylthiophene-2-sulfonamide
Inchi Key	OALICVBQMFNIMZ-MUUNZHRXSA-N
Inchi ID	InChI=1S/C33H42N4O5S2/c1-34(44(39,40)32-13-7-21-43-32)16-6-12-28(24-14-15-30(41-2)31(22-24)42-3)37-23-27-26(33(37)38)10-5-11-29(27)36-19-17-35(18-20-36)25-8-4-9-25/h5,7,10-11,13-15,21-22,25,28H,4,6,8-9,12,16-20,23H2,1-3H3/t28-/m1/s1
PubChem CID	25127072
ChEMBL	CHEMBL571537
IUPHAR	N/A
BindingDB	50302266
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
236454	Urotensin-2 receptor	P49684	Uts2r	Rattus norvegicus (Rat)	386
236455	Urotensin-2 receptor	Q9UKP6	UTS2R	Homo sapiens (Human)	389

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