i-TASSER Ab initio FM
Posted: Tue Apr 02, 2024 8:31 am
Dear Zhang Lab,
I have a protein with quite low coverage of template, and I want to predict its 3D structe with good quality. It has a good coverage only at the domain side, and PDB proteins that cover the domain does not cover the whole protein. Therefore, the rest of it has no template to fold according to.
I was wondering if i-TASSER does TBM to this domain side and ab initio FM to the rest of the protein at the same time? If so, how can I do it? Also, how to do only ab initio FM at i-TASSER?
I have a protein with quite low coverage of template, and I want to predict its 3D structe with good quality. It has a good coverage only at the domain side, and PDB proteins that cover the domain does not cover the whole protein. Therefore, the rest of it has no template to fold according to.
I was wondering if i-TASSER does TBM to this domain side and ab initio FM to the rest of the protein at the same time? If so, how can I do it? Also, how to do only ab initio FM at i-TASSER?