I-tasser showing different secondary structure in 3D model

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Humayun Arshad
Posts: 1
Joined: Tue Apr 27, 2021 10:44 am

I-tasser showing different secondary structure in 3D model

Post by Humayun Arshad »

I submitted a job at i-tasser. The predicted 3D models do not have same secondary structure elements as listed under "Predicted Secondary Structure."
I am unable to understand this discrepancy. Can you please help me in this regard. The link of the job is given below.
https://zhanglab.dcmb.med.umich.edu/I-T ... t/S609759/
xiaogenz
Posts: 14
Joined: Sun Apr 25, 2021 12:02 am

Re: I-tasser showing different secondary structure in 3D model

Post by xiaogenz »

I think this is normal because the predicted secondary structure is not completely correct. The simulation will correct some unreasonable regions according to the template information and the energy, which reults in the secondary structure in the final model is different from the predicted one.
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