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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	diclofenac
Molecular formula	C14H11Cl2NO2
IUPAC name	2-[2-(2,6-dichloroanilino)phenyl]acetic acid
Molecular weight	296.147
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.4
Synonyms	SCHEMBL2799 Spectrum3_000385 TC-110178 Voltaren-XR [2-(2,6-dichloro-phenylamino)-phenyl]-acetic acid Prestwick1_000594 NINDS_000272 dichlofenac Diclofenac acid 15307-86-5 Diclofenamic acid 2-[(2,6-dichlorophenyl)amino]-phenyl-acetic acid DivK1c_000402 2-[2-(2,6-dichlorophenylamino)phenyl]-acetic acid Effekton AC-27673 HMS2090C10 Apo-Diclo KBio1_000272 Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)- (9CI) KBio3_001389 BSPBio_002169 Lopac0_000441 CS-2862 Solaraze (TN) Spectrum_000930 Voldal Z57664869 [2-(2,6-Dichloroanilino)phenyl]acetic acid # Primofenac D0TG1H Novo-Difenac Diclo-Puren Diclofenac [USAN:INN:BAN] 2-(2-((2,6-Dichlorophenyl)amino)phenyl)acetic acid Diclord 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID Duravolten 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid F0722-0745 ACMC-209d8r HY-15036 BCP09087 KBio2_002306 BPBio1_000516 KBioGR_002306 CGP-45840B MCULE-1824024270 SPBio_002687 ST51039044 Voltaren Rapide Zorvolex Pennsaid SBI-0051341.P003 NCGC00021125-01 DB00586 o-(2,6-dichloroanilino)phenylacetic acid Diclofenac (sodium matrix patch, pain) 144O8QL0L1 Diclofenacum 2-[(2,6-dichlorophenyl)-amino]-phenyl-acetic acid DIF 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid EC 239-348-5 AB01275502_02 GP-45840 AKOS001579542 IDI1_000402 Benfofen KBio2_006546 BRN 2146636 KS-000001OB CHEMBL139 SMR001550371 Spectrum4_000506 UNII-144O8QL0L1 Voltarol [2-(2,6-Dichloroanilino)phenyl]-acetic acid; 2-[2-(2,6-Dichlorophenyl)aminophenyl]ethanoic acid Prestwick2_000594 CTK8B0851 NINDS_000402 Dichlofenal Diclofenac resinate 2-((2,6-Dichlorophenyl)amino)benzeneacetic acid Diclonate P 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid Dolobasan 2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetic acid EINECS 239-348-5 AC1L1F0T HMS501E04 Assaren KBio1_000402 Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]- KBio3_002786 C01690 LS-11575 Solaraze T SR-01000003041-3 Voltaren ZINC1281 [o-(2,6-dichloro-anilino)-phenyl]-acetic acid Olfen ProSorb-D D30801 Novo-Difenac SR Diclobenin 056D694 Diclofenaco 2-(2-(2,6-dichlorophenylamino)phenyl)acetic acid Dicloreum 2-[2-(2,6-dichloroanilino)phenyl]acetic acid Dyloject 2b17 FT-0624731 AJ-07992 I14-7739 BCP13860 KBio2_003978 BRD-K08252256-236-05-6 KBioSS_001410 CHEBI:47381 MLS006011795 Spectrum2_000991 STK984493 Voltaren SR Zorvolex (TN) Prestwick0_000594 SC-16284 NCGC00021125-02 DCOPUUMXTXDBNB-UHFFFAOYSA-N Diclofenac (USAN/INN) 15307-81-0 (mono-potassium salt) Diclofenacum [INN-Latin] 2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid DivK1c_000272 2-[2-(2,6-dichlorophenylamino)-phenyl]-acetic acid Ecofenac AB1009343 GTPL2714 ANW-21433 ISV-205 Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)- KBio2_007442 BSPBio_000468 KS-1258 cMAP_000014 Solaraze Spectrum5_000867 UNM000001216103 Xenid [2-(2,6-Dichloroanilino)phenyl]acetic acid Prestwick3_000594 D07816 Novapirina Diclo-Phlogont Diclofenac [INN:BAN] 2-(2,6-Dichloroanilino)phenylacetic Acid Diclophenac 2-[(2,6-dichlorophenyl)amino]phenylacetic acid DTXSID6022923 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetic Acid (Diclofenac) Epitope ID:116873 ACETIC ACID, (o-(2,6-DICHLOROANILINO)PHENYL)- HSDB 7234 BC208012 KBio2_001410 BIDD:GT0380 KBioGR_001051 Cataflam M-7482 SPBio_001081 SR-38 Voltaren Ophtha Zorovolex {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid Oprea1_011155 Rhumalgan MolPort-000-003-072 D3748 Nu-Diclo Diclofenaco [INN-Spanish] 2-[(2,6-dichlorophenyl)-amino]-benzeneacetic acid Dicrofenac 2-[2-(2,6-dichloroanilino)phenyl]acetic acid. EBD50236 AB01275502-01 GP-45,840 AK-75694 IDI1_000272 BDBM13066 KBio2_004874 BRD-K08252256-236-17-1 KBioSS_002308 [ Show all ]
Inchi Key	DCOPUUMXTXDBNB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
PubChem CID	3033
ChEMBL	CHEMBL139
IUPHAR	N/A
BindingDB	13066
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
56539	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350

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