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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1946780
Molecular formula	C28H32N2O2
IUPAC name	1-[(5,5-diphenyloxolan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Molecular weight	428.576
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50419718 CHEMBL1962870 1-(5,5-Diphenyltetrahydrofuran-2-ylmethyl)-4-(2-methoxyphenyl)piperazine J3.595.106G
Inchi Key	DKZVZJLNJPUMKG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H32N2O2/c1-31-27-15-9-8-14-26(27)30-20-18-29(19-21-30)22-25-16-17-28(32-25,23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15,25H,16-22H2,1H3
PubChem CID	56946573
ChEMBL	CHEMBL1962870
IUPHAR	N/A
BindingDB	50419718
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62766	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
62768	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
62767	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
62765	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
523363	Trace amine-associated receptor 1	Q923Y8	Taar1	Mus musculus (Mouse)	332
523362	Trace amine-associated receptor 5	Q5QD14	Taar5	Mus musculus (Mouse)	337

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