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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL226124
Molecular formula	C34H44F2N4
IUPAC name	1-[1-(4-fluorophenyl)-2-[4-[3-(4-fluoro-2-phenylphenyl)propyl]piperazin-1-yl]ethyl]-4-propan-2-ylpiperazine
Molecular weight	546.751
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.4
Synonyms	BDBM50202934 (+/-)-1-[3-(5-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-4-isopropylpiperazin-1-yl)ethyl]piperazine
Inchi Key	DRSLEYLXVNRDKA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H44F2N4/c1-27(2)39-21-23-40(24-22-39)34(30-11-13-31(35)14-12-30)26-38-19-17-37(18-20-38)16-6-9-29-10-15-32(36)25-33(29)28-7-4-3-5-8-28/h3-5,7-8,10-15,25,27,34H,6,9,16-24,26H2,1-2H3
PubChem CID	44423455
ChEMBL	CHEMBL226124
IUPHAR	N/A
BindingDB	50202934
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
67263	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
67266	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
67264	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
67265	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
67262	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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