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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1165432
Molecular formula	C29H26FN5O4
IUPAC name	N-[4-[3-[(3-amino-2,2-dimethylpropyl)carbamoyl]phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Molecular weight	527.556
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	4.2
Synonyms	N-[4-{3-[(3-Amino-2,2-dimethylpropyl)carbamoyl]-phenyl}-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]-furan-2-carboxamide SCHEMBL13801716 BDBM50320823
Inchi Key	FNXVBWFYIVIMIU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H26FN5O4/c1-29(2,15-32)16-33-27(37)18-6-3-5-17(11-18)21-13-23(20-9-8-19(30)12-24(20)36)34-26(22(21)14-31)35-28(38)25-7-4-10-39-25/h3-13,36H,15-16,32H2,1-2H3,(H,33,37)(H,34,35,38)
PubChem CID	136016412
ChEMBL	CHEMBL1165432
IUPHAR	N/A
BindingDB	50320823
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
559877	KiSS-1 receptor	Q969F8	KISS1R	Homo sapiens (Human)	398

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